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Wrapping up the week by visualizing the crazy axonal growth of dorsal root ganglia neurons in vitro using the SPY650-FastAct probe from Spirochrome! 🤩 Capturing one image every 10 minutes.

Alexandre Dumoulin @axonsalex.bsky.social

1,346 subscribers

50,654 views • 2 years ago •via X (Twitter)

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10 Comments

Augusto Escalante2 years ago

@spirochrome Beautiful, Alex! DRG explant? Mouse or chick?

Alexandre Dumoulin @axonsalex.bsky.social2 years ago

@spirochrome thanks Augusto! E5 chick DRG explants plated on PLL-laminin substrate 😉

Luc Reym⌬nd2 years ago

@spirochrome Absolutely mind-blowing, congratulations! Is there some chemoattractant in the upper-left quadrant to direct the growth?

Alexandre Dumoulin @axonsalex.bsky.social2 years ago

@spirochrome Thanks! No, there is no chemoattractant gradient, just NGF in the medium. DRG axons sprouting out of an explant grow "naturally" outward in a radial manner.

Danielle Beckman2 years ago

@spirochrome Perfect #FluorescenceFriday!

Karen Muller Smith2 years ago

@spirochrome This is just fire! I love it!

Cankay Koryak2 years ago

@spirochrome Wow

vero_mb2 years ago

@spirochrome I love it 😍

Matteo Ruggiu, PhD 🇺🇦2 years ago

@spirochrome That's insane!

Manasi Agrawal, Ph.D.2 years ago

@spirochrome That is stunning!!

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