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๐๐๐. ๐๐๐ง๐ง๐๐๐ฒ ๐ฌ๐๐ฒ๐ฌ ๐ญ๐ก๐๐ญ ๐ญ๐ก๐ ๐ ๐๐ ๐ข๐ฌ ๐ ๐จ๐ข๐ง๐ ๐ญ๐จ ๐๐๐๐๐ฅ๐๐ซ๐๐ญ๐ ๐๐ซ๐ฎ๐ ๐๐ฉ๐ฉ๐ซ๐จ๐ฏ๐๐ฅ๐ฌ ๐ฐ๐ข๐ญ๐ก ๐๐ ๐๐ฒ ๐ฌ๐ค๐ข๐ฉ๐ฉ๐ข๐ง๐ ๐๐ง๐ข๐ฆ๐๐ฅ ๐ญ๐ซ๐ข๐๐ฅ๐ฌ Iโve watched the entire Tucker Carlson interview with RFK Jr. I was already familiar with most of the information presented there. RFK Jr. has been repeating this info for a while... show more
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2/4 So essentially RFK Jr. is talking about skipping animal trials, and replacing them with AI models. The importance of animal trials with drugs and other medical interventions is that you can perform intrusive exams on these animals (including autopsies) and actually see what were the effects of the drug being tested. It gives insights that you cannot get through human trials or AI models. Removing animal trials from the process will prevent us from getting that insight and, possibly, moving ahead with a drug that is dangerous. For example, an animal trial on rats about the lipid nano particles that were used in the Covid mRNA shots (the particle carrying the mRNA itself) showed that these particles get into every organ in the body, and doesnโt stay localized to the place of the injection (as was later claimed by Pfizer). This study should have been enough to prevent human trials, but was ignored. โ

3/4 According to Grok, one of the ways AI can be used to drug approvals is by doing In Silico Modeling and Simulation: AI can create advanced computational models to simulate drug interactions with biological systems, often referred to as โin silicoโ trials. These models use machine learning (ML) to predict how drugs will behave in the human body, reducing the need for traditional animal testing or early-phase human trials. Or AI-driven simulations can predict pharmacokinetics (how a drug moves through the body), pharmacodynamics (drug effects), and toxicity profiles. For example, physiologically based pharmacokinetic (PBPK) models enhanced by AI can simulate drug responses across diverse populations. The main problem with these simulations is that they assume that science is already familiar with all the variables that have an effect on these complex systems. It is too much hubris to pretend that we do. In other words, a model based on an incomplete set of variables will result in wrong or incomplete results: Garbage In - Garbage Out โผ๏ธ โ

4/4 Also according to Grok: Companies like Simulations Plus use AI-driven PBPK models to predict drug safety, which the FDA accepts as part of regulatory submissions. RFK Jr.โs mention of bypassing animal models aligns with this trend, as AI can simulate outcomes that traditionally required primate or rodent studies. RFK Jr. is a very well read guy and has spent decades reading and studying peer reviewed papers, publications and clinical trials, but he is clearly not a scientist, and he is not well versed in the scientific method. But he has placed many respected scientists in leadership positions within his agency. Thus, it is perplexing to me hearing that he is taking this approach to clinical trials. Either he has been convinced that this is โgood scienceโ, or he is under pressure somehow from Big Pharma interests. And how come these other scientists in top positions have said nothing about this and went along with it? I hope that we will get a more clear answers in the coming monthsโฆ โ

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We don't need Quickly...This is Madness.And BTW.Why would anybody trust these people ever again?

Open air lab All of you

@RobertKennedyJr This is BS. WTF is wrong with you? Screw up your job and endure that the Kennedy name is sh*t.

Tbt I m good with no animal testings. Theyโre obsolete and sadistic. Thereโs nothing more to glean from it either.

I donโt see that short clip as being bad. Heโs talking about looking at the vaers data. Comparing 3 types of diabetes drugs and looking at the results and seeing which drug had the best results. What has been done in the past 20 years to improve healthcare.
