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โ€œ๐—Ÿ๐—ฎ๐˜€๐˜ ๐—ป๐—ฎ๐—บ๐—ฒ ๐—š๐—ฎ๐˜€๐˜€๐—ฒ๐˜๐˜ ๐—ณ๐—ผ๐—ฟ ๐—ฎ ๐—ฟ๐—ฒ๐—ฎ๐˜€๐—ผ๐—ป, ๐—œ ๐—ฐ๐—ผ๐—บ๐—ฒ ๐˜„๐—ถ๐˜๐—ต ๐—ด๐—ฎ๐˜€. ๐—œ ๐—ฑ๐—ผ๐—ปโ€™๐˜ ๐—ด๐—ฒ๐˜ ๐˜๐—ถ๐—ฟ๐—ฒ๐—ฑ.โ€ Jamari Gassett was unguardable in the 24-23 win vs. Norfolk State, catching 8 passes for 110 yards and two touchdowns. #FAMU | #Rattlers | #RELOAD | #REPEAT

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@FAMUAthletics @AlisonPosey14 @3peatgee @RyanLKelly @sydney_wicker @FAMU_1887 @JamariGassett18 @NCAA_FCS @LightOnSports ๐Ÿ”ฅ๐Ÿ”ฅ๐Ÿ”ฅ๐Ÿ”ฅ๐Ÿ”ฅ๐Ÿ๐Ÿ๐Ÿ๐Ÿˆ๐Ÿˆ๐Ÿˆ

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๐Ÿšจ New games alert! ๐Ÿšจ The latest titles from Boldplay are just around the corner! ๐ŸŽฐ Dive in, grab your daily bits, and get ready to play. Big fun and rewards await! ๐Ÿ’ฅ ๐Ÿ‘‰ Donโ€™t miss outโ€”start playing today! #BoldPlay #Kickr #NewGames #DailyBonus

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8th Anniversary for 2nd and 26 Eight years ago today, on January 8, 2018, Tua Tagovailoa connected with DeVonta Smith for a stunning 41-yard touchdown pass in overtime, securing a victory against the Georgia Bulldogs. This dramatic play clinched a walk-off championship for the Crimson Tide, marking Nick Saban's 5th national title in Tuscaloosa and the 17th national title in school history. Alabama beat UGA 26-23 in OT Do you believe that the 2nd and 26 play is the greatest play in Alabama history? Saban made a bold decision at halftime by benching Jalen Hurts after a challenging first half. Tua Tagovailoa proved to be the spark the Crimson Tide needed, catching Georgia off guard with his unique style of play. When I reflect on this game, I think about two players, Christian Miller and Terrell Lewis, who suffered injuries in the first game of the season against Florida State. These injuries were initially considered season-ending, but thanks to their hard work and dedication to extra rehab, both players managed to return in time for the National Championship. They played vital roles for the Crimson Tide during the Championship game, with Lewis making a crucial play in overtime that forced Georgia to kick a field goal. This gave Alabama the opportunity to score a touchdown and win the game. In the second half, Tua Tagovailoa had 14 completions on 24 attempts for 165 yards, with 3 touchdowns and 1 interception. In the first half, Jalen Hurts was 3 for 8 with 21 yards, 0 touchdowns, 0 interceptions, and had 47 yards rushing. Najee Harris contributed with 6 carries for 47 yards, and DeVonta Smith had 1 reception for 41 yards, which was the winning touchdown. Roll Tide to group a special group of players.

Ryan C. Fowler

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SD Mines accepted an invite to play Division 1 Drake on Thursday night (8/27/26) to kick off the season, and not only did they leave Des Moines with a nice payday, but also left with a 38-35 victory. Despite falling behind 10-0 in the 1st Quarter, the Hardrockers responded with a heavy dose of Dawson Dunbar, who scored the next two touchdowns on a 58 yard screen pass and a 49 yard run down the Bulldogsโ€™ throats to take a 17-13 lead into halftime. In the 3rd Quarter, Gage Baker found former high school teammate Joshua Morales and tight end Blake Borchers for touchdown passes of 44 yards and 36 yards respectively. When momentum turned in Drakeโ€™s favor in the 4th quarter, the Hardrockers displayed the grit and perseverance we have all come to expect from a Coach Flohr team. With 7:45 remaining in the game, the Hardrockers went on a 15 play 79 yard drive that ate up 5:55 off the clock and ended with Dawson Dunbar refusing to go down until he ran it in from 3 yards out for the go ahead touchdown. While Drake had the ball with 1:50 remaining, SD Mines put the nail in the coffin with a huge interception by Senior Linebacker Charlie Johnson. Leading SD Mines to the win were: ๐Ÿˆ Gage Baker, 19 Cmps on 31 Atts for 306 Yds & 3 TDs; ๐Ÿˆ Dawson Dunbar, 17 Carries for 120 Yds and 2 rushing TDs & 3 Recs for 94 Yds and 1 receiving TD; ๐Ÿˆ Ty Harris, 23 Carries for 108 Yds; ๐Ÿˆ Joshua Morales, 4 Recs for 84 Yds & 1 TD; ๐Ÿˆ Charlie Johnson, 12 Tackles (5 Solo & 7 Ast) with 1 TFL & 1 INT; & ๐Ÿˆ Jarin Allen, 8 Tackles (7 Solo & 1 Ast). SD Mines will welcome Southwest Baptist to Rapid City next weekend as they attempt to built off the momentum from Thursdayโ€™s win. Here are a few Hardrockersโ€™ highlights from Thursdayโ€™s victory: #RMAC #RMACfb #SDMinesFB #RiseOfTheRockers

RMAC Insider

31,140 Aufrufe โ€ข vor 1 Monat

๐—•๐—ฒ๐—ฟ๐—น๐—ถ๐—ป ๐—ฟ๐—ฒ๐—ฐ๐—ฎ๐—ฝ. ๐Ÿงต This weekend, I flew from Rabat to Berlin for Founders Eve by Arbitrum & DeFi Founders Club. 24 hours of travel. Straight into one of the most stacked rooms of builders I've been in this year. ๐—ง๐—ต๐—ฒ ๐—ฏ๐—ฒ๐˜€๐˜ ๐—ฝ๐—ฎ๐—ฟ๐˜ ๐˜„๐—ฎ๐˜€๐—ปโ€™๐˜ ๐˜๐—ต๐—ฒ ๐—ฐ๐—ผ๐—บ๐—ฝ๐—ฒ๐˜๐—ถ๐˜๐—ถ๐—ผ๐—ป. It was the people. Every team I met was building something ambitious! No ๐Ÿงข. No tourists. No noise. Just founders obsessed with their mission. I pitched Didn't win. And honestly, that's okay ๐Ÿ™‚โ€โ†•๏ธ A 2-minute pitch was never enough to explain everything Iโ€™ve spent years building: โ†’ 11+ AI agents working together โ†’ Gasless UX โ†’ Account abstraction โ†’ Arbitrum-powered rails โ†’ Fully automated workflows โ†’ AI-native financial infrastructure But that's part of the game. ๐—ฆ๐—ผ๐—บ๐—ฒ๐˜๐—ถ๐—บ๐—ฒ๐˜€ ๐˜†๐—ผ๐˜‚ ๐˜„๐—ถ๐—ป ๐˜๐—ต๐—ฒ ๐—ฝ๐—ฟ๐—ถ๐˜‡๐—ฒ. ๐—ฆ๐—ผ๐—บ๐—ฒ๐˜๐—ถ๐—บ๐—ฒ๐˜€ ๐˜†๐—ผ๐˜‚ ๐˜„๐—ถ๐—ป ๐˜๐—ต๐—ฒ ๐—ฐ๐—น๐—ฎ๐—ฟ๐—ถ๐˜๐˜†. What surprised me most happened after the pitch. I got feedback from founders, VCs, and ecosystem leaders. The kind of advice that can save months of building. One word kept coming up: ๐—™๐—ผ๐—ฐ๐˜‚๐˜€. So Iโ€™m acting on it. TogetherFi is now doubling down on: โ†’ CreatorFi โ†’ GameFi โ†’ SocialFi Building the infrastructure layer for the programmable economy powered by AI. And here's the interesting part: Several VCs reached out directly after the event. Not because we wonโ€ฆ Because they understood the vision. ๐—” ๐—ฝ๐—ถ๐˜๐—ฐ๐—ต ๐—ฟ๐—ฒ๐˜€๐˜‚๐—น๐˜ ๐—ฑ๐—ผ๐—ฒ๐˜€๐—ปโ€™๐˜ ๐—ฑ๐—ฒ๐—ณ๐—ถ๐—ป๐—ฒ ๐—ฎ ๐—ฐ๐—ผ๐—บ๐—ฝ๐—ฎ๐—ป๐˜†. Execution does. After the Arbitrum Founders eve, the night kept going. Shoutout to CHAINFLIP for the invite, then another event, and later an amazing rooftop with the LUKSO team. โ–ซ๏ธMet incredible people. โ–ซ๏ธExchanged contacts. โ–ซ๏ธReconnected with friends I first met in Cannes and Paris. ๐—ง๐—ต๐—ฎ๐˜โ€™๐˜€ ๐˜„๐—ต๐—ฎ๐˜ ๐—บ๐—ฎ๐—ธ๐—ฒ๐˜€ ๐˜๐—ต๐—ถ๐˜€ ๐˜€๐—ฝ๐—ฎ๐—ฐ๐—ฒ ๐˜€๐—ฝ๐—ฒ๐—ฐ๐—ถ๐—ฎ๐—น. The events last a few hours. The relationships last years. By Tuesday morning, I was already back on the road. Berlin โ†’ Paris โ†’ Rabat. Back to my family. Back to building. Back to executing. Didn't leave Berlin with a trophy. ๐—œ ๐—น๐—ฒ๐—ณ๐˜ ๐˜„๐—ถ๐˜๐—ต: โ†’ New relationships โ†’ Better focus โ†’ Valuable feedback โ†’ Stronger conviction Sometimes that's the bigger win. We're just getting started. ๐Ÿ’™๐Ÿงก #Arbitrum #BerlinBlockchainWeek #TogetherFi

Alpha

16,462 Aufrufe โ€ข vor 3 Monaten

๐—ง๐—ต๐—ฒ $NWBO ๐——๐—–๐—ฉ๐—ฎ๐˜…-๐—Ÿ ๐˜๐—ฟ๐—ถ๐—ฎ๐—น ๐—ถ๐˜€ ๐—ฎ๐—น๐—ฟ๐—ฒ๐—ฎ๐—ฑ๐˜† ๐—ฑ๐—ผ๐—ป๐—ฒ. ๐—ง๐—ต๐—ฒ ๐—™๐——๐—” ๐—ต๐—ฎ๐˜€ ๐—ฎ๐—น๐—ฟ๐—ฒ๐—ฎ๐—ฑ๐˜† ๐˜„๐—ฟ๐—ถ๐˜๐˜๐—ฒ๐—ป ๐˜๐—ต๐—ฒ ๐—ฝ๐—น๐—ฎ๐˜‚๐˜€๐—ถ๐—ฏ๐—น๐—ฒ ๐—บ๐—ฒ๐—ฐ๐—ต๐—ฎ๐—ป๐—ถ๐˜€๐—บ ๐—ฝ๐—ฎ๐˜๐—ต๐˜„๐—ฎ๐˜†. ๐—ช๐—ต๐—ฎ๐˜ ๐—ถ๐˜€ ๐—น๐—ฒ๐—ณ๐˜ ๐—ถ๐˜€ ๐˜๐—ผ ๐—ฎ๐˜€๐˜€๐—ฒ๐—บ๐—ฏ๐—น๐—ฒ ๐—ถ๐˜ ๐—ฎ๐—ป๐—ฑ ๐—ณ๐—ถ๐—น๐—ฒ. #DCVax-L is a vaccine made for each patient from their own dendritic cells, the immune cells that teach the rest of the immune system what to attack, loaded with their own tumor. It treats #glioblastoma, the deadliest brain cancer. An American company developed it, yet Americans have to go to Europe to get it. #DCVaxForBraelyn The FDA has spent the past year writing down how it wants to judge treatments like this one. The core evidence it asks for already exists. One question decides this: can the FDA evaluate DCVax-L for approval under the plausible mechanism framework, on the evidence already generated? Read against every document the agency has published on the framework, the answer is yes. ๐—ง๐—ต๐—ฒ ๐—ฝ๐—น๐—ฎ๐—ป ๐—ถ๐—ป ๐˜๐—ต๐—ฟ๐—ฒ๐—ฒ ๐˜€๐˜๐—ฒ๐—ฝ๐˜€ 1. File the biologics license application (BLA) and ask the FDA's biologics center (CBER) for review under the plausible mechanism framework. A BLA is not another trial. It is the dossier the FDA decides on, and the framework changes what counts as sufficient inside it. The framework itself needs no new statute and no special designation. A sponsor asks for it. 2. Ask for full approval on survival, with no new randomized trial. The completed phase 3 is the pivotal study. Mechanism, a related product, a related stage of the disease and independent natural history are the confirmatory evidence. A registry of every treated patient supplies the follow-up. 3. Open access alongside the filing. An expanded access treatment protocol does not have to wait for the BLA; it can begin 30 days after the FDA receives it. Filing the BLA satisfies Right to Try's application condition. ๐—ช๐—ต๐—ฎ๐˜ ๐˜๐—ต๐—ฒ ๐—™๐——๐—” ๐—ต๐—ฎ๐˜€ ๐˜„๐—ฟ๐—ถ๐˜๐˜๐—ฒ๐—ป ๐—ฑ๐—ผ๐˜„๐—ป Nov 2025, NEJM, Prasad and Makary: the plausible mechanism framework. Five questions. Built for cell and gene therapies first, and available for common diseases, particularly those "for which there are no proven alternative treatments." Feb 2026, NEJM: one adequate and well-controlled study plus confirmatory evidence is the FDA's default basis for approval. Feb 2026 draft guidance: an externally controlled study against a well-characterized natural history can be the pivotal study. Confirmatory evidence includes mechanism, target engagement and "exposure-response on biomarkers and clinical outcomes." The product can target "a well-characterized downstream or compensatory mechanism with a clear mechanistic rationale." June 2026 draft guidance: six conditions under which an external control supports effectiveness. The plausible mechanism framework named as an example of FDA regulatory flexibility in critical settings. "Even small effects may be clinically meaningful when the effect is on survival or irreversible morbidity." Why it exists: to bring regulatory flexibility to individualized therapies where the conventional model does not fit. The guidance names gene and RNA therapies, then says "the general concepts may apply to other types of individualized therapies": therapies that target "a specific pathophysiologic abnormality serving as the root cause of a disease." The FDA's own announcement: the guidance "leaves open the potential that this framework may apply to additional tailored therapeutics provided they directly address the underlying specific cause of the disease." The framework is not a new approval standard. It is how the FDA reads evidence under the standard that already exists. That is exactly why it can be asked for today. ๐—ช๐—ต๐˜† ๐—ด๐—น๐—ถ๐—ผ๐—ฏ๐—น๐—ฎ๐˜€๐˜๐—ผ๐—บ๐—ฎ ๐—ถ๐˜€ ๐˜๐—ต๐—ฒ ๐—ฐ๐—ฎ๐˜€๐—ฒ ๐—ถ๐˜ ๐˜„๐—ฎ๐˜€ ๐˜„๐—ฟ๐—ถ๐˜๐˜๐—ฒ๐—ป ๐—ณ๐—ผ๐—ฟ No proven alternative: recurrent GBM has no established standard of care. Of 400+ trials since 2005, only one phase 3 in newly diagnosed and none in recurrent disease had shown a survival benefit. High and predictable mortality: the exact case FDA regulations name for historical controls, "certain malignancies." Life-threatening in the regulation's own terms: a disease "where the end point of clinical trial analysis is survival." Individualized: a different product for every patient, made from their own cells and their own tumor, aimed at the root cause, the broken instruction layer. Orphan designation in the US and Europe. ๐—ง๐—ต๐—ฒ ๐—ฝ๐—ถ๐˜ƒ๐—ผ๐˜๐—ฎ๐—น ๐˜€๐˜๐˜‚๐—ฑ๐˜† ๐—ถ๐˜€ ๐—ฐ๐—ผ๐—บ๐—ฝ๐—น๐—ฒ๐˜๐—ฒ 331 patients, 94 sites, randomized, double blind. 64 of 99 placebo patients crossed over at recurrence, so survival was measured against 2,006 contemporaneous matched control patients from 15 randomized trials. Newly diagnosed: 19.3 vs 16.5 months, HR 0.80, p=.002. Alive at 5 years: 13.0% vs 5.7%. Recurrent: 13.2 vs 7.8 months, HR 0.58, p<.001. That is a 42% lower risk of death. The benefit widened over time, and it was largest in the patients who fare worst. Why no second trial? The completed trial, the crossover and the survival evidence make the case, and the FDA's June guidance names the ethical stake: after "a substantial decrease in mortality," a second trial "would generally present significant ethical concerns." ๐—ง๐—ต๐—ฒ ๐Ÿฎ๐Ÿฌ๐Ÿฎ๐Ÿฒ ๐—ฟ๐—ฒ๐—ฎ๐—ป๐—ฎ๐—น๐˜†๐˜€๐—ถ๐˜€ The phase 3 paper named its own limitation: without patient-level control data, "propensity score matching could not be performed." The critics named the missing methods: "propensity score matching or inverse probability weighting." In 2026 Northwest obtained individual patient data from three independent randomized trials and had independent statisticians run exactly those two methods. Propensity score matching pairs each DCVax-L patient with control patients who had the same prognostic profile, so like is compared with like. Presented at BNOS in July 2026; peer-reviewed publication is the next step. Propensity score matching: HR 0.69 to 0.77. Median survival +3.4 to +6.3 months. p .004 to .027. The original cohort-level analysis showed +2.8. When the matching got finer, the benefit got bigger. The survival advantage held under both patient-level methods and was larger than the original cohort-level estimate. Northwest reports sensitivity analyses for hidden confounding; the published paper should give the values. The method has been tested in this exact disease. In May 2026, the INSIGhT investigators replaced their own randomized control arm with propensity-matched external controls. For three drugs that had failed randomized testing, the method also found no benefit: HR 1.00, 0.93, 0.88. "Carefully matched external controls" produced "treatment effect estimates that were similar" to the randomized analyses. The method did not invent a benefit. Applied to DCVax-L, it found one. And the authorship closes the loop. In 2023, Dana-Farber statisticians Rahman, Ventz and Trippa wrote that they were "not aware of independent validations of these analytic methods in a GBM trial context." Rahman and Trippa are the senior authors of the 2026 INSIGhT validation. The critics asked for patient-level data and a validated method. By 2026 both existed. That supports the method the DCVax-L reanalysis used; publishing that analysis in full is step one. And it is the form a BLA requires: FDA guidance says applications "must include" patient-level data for the external control arm. ๐—ง๐—ต๐—ฒ ๐—™๐——๐—”'๐˜€ ๐˜€๐—ถ๐˜… ๐˜๐—ฒ๐˜€๐˜๐˜€ ๐—ณ๐—ผ๐—ฟ ๐—ฎ๐—ป ๐—ฒ๐˜…๐˜๐—ฒ๐—ฟ๐—ป๐—ฎ๐—น ๐—ฐ๐—ผ๐—ป๐˜๐—ฟ๐—ผ๐—น, ๐—ฎ๐—ป๐˜€๐˜„๐—ฒ๐—ฟ๐—ฒ๐—ฑ 1. Well-defined natural history: 2,006 controls from 15 randomized trials. 2. Very similar populations: 14 prespecified criteria, chosen by an independent firm, validated against all 15 source trials, now matched patient by patient. 3. Similar treatments: in newly diagnosed disease, surgery, radiation and temozolomide in both groups. 4. Objective endpoint: death. 5. Comparable start: survival from randomization after radiotherapy in both groups. Drop the two control trials that admitted early progressors: HR still 0.80. 6. An effect too large to be bias: five-year survival more than doubled, HR 0.58 at recurrence, and the effect grew when matching tightened. ๐—ง๐—ต๐—ฒ ๐—ฝ๐—น๐—ฎ๐˜‚๐˜€๐—ถ๐—ฏ๐—น๐—ฒ ๐—บ๐—ฒ๐—ฐ๐—ต๐—ฎ๐—ป๐—ถ๐˜€๐—บ ๐—ฐ๐—ฟ๐—ถ๐˜๐—ฒ๐—ฟ๐—ถ๐—ฎ, ๐˜„๐—ผ๐—ฟ๐—ฑ ๐—ณ๐—ผ๐—ฟ ๐˜„๐—ผ๐—ฟ๐—ฑ The FDA's five elements, quoted exactly from its February 2026 draft guidance ( lines 26 to 32), each answered: 1. "Identifying a specific genetic, cellular, or molecular abnormality with a clear connection between specific alteration and disease indication." (line 26) โœ“ Met: in GBM, the dendritic cells that should teach T cells what to attack are overridden by suppressive immune cells. A tumor never presented for attack grows unopposed. 2. "Developing a therapy that targets the underlying or proximate pathogenic biological alterations." (line 28) โœ“ Met: DCVax-L supplies the patient's own dendritic cells, loaded with their own tumor and prepared outside the suppressive tumor environment, to restore tumor-directed T-cell instruction. 3. "Relying on a well-characterized natural history of the disease in an untreated population." (line 30) โœ“ Met: 2,006 controls from 15 randomized trials, patient-level data from three more, no time-trend in survival 2012 to 2022. 4. "Confirming that the target was successfully drugged or edited or both." (line 31) โœ“ Platform evidence documented; product-specific bridge required. After DC vaccination, cytotoxic T cells increased inside the tumor, and infiltration correlated with survival (P = 0.047); T cell infiltration in the UCLA vaccine-first arm. The FDA is open to confirmation "for a subset of patients"; the BLA should supply DCVax-L's own immune-monitoring results and the bridge to these studies. 5. "Demonstrating improvement in clinical outcomes or course." (line 32) โœ“ Met: longer survival, five-year survival more than doubled, a bigger benefit under patient-level matching. The eight considerations attached, each answered: 1. An individualized therapy aimed at "a specific pathophysiologic abnormality" 2. A "compensatory mechanism with a clear mechanistic rationale" 3. Substantial evidence from "a single adequate and well-controlled clinical investigation with confirmatory evidence" 4. A natural history that lets the effect be "reasonably distinguished from natural variability" 5. An improvement not attributable to "alternative treatments or natural variability" 6. Prespecified analysis plans 7. A reason a new RCT is not feasible 8. A product that "can be manufactured to regulatory quality standards," made for every phase 3 patient: manufacturing experience documented, US CMC review required 13 of 13, every one in the FDA's own words, every one answered from the record, every open step named. ๐—ง๐—ต๐—ฒ ๐—ฐ๐—ผ๐—ป๐—ณ๐—ถ๐—ฟ๐—บ๐—ฎ๐˜๐—ผ๐—ฟ๐˜† ๐—ฒ๐˜ƒ๐—ถ๐—ฑ๐—ฒ๐—ป๐—ฐ๐—ฒ, ๐—ถ๐—ป ๐˜๐—ต๐—ฒ ๐—™๐——๐—”'๐˜€ ๐—ผ๐˜„๐—ป ๐—ฐ๐—ฎ๐˜๐—ฒ๐—ด๐—ผ๐—ฟ๐—ถ๐—ฒ๐˜€ Mechanism: in the DCVax-Direct phase 1 (a different product: activated dendritic cells injected into diverse solid tumors), more IL-8 and IL-12p40 from each patient's cells went with longer survival, p=0.023 and 0.024. Exposure-response, in the FDA's words. Related product: UCLA's 46-patient randomized phase 1 trial of its own tumor lysate DC vaccine, at EANO this Friday. Both arms got the vaccine; the order was randomized. Vaccine first, 555 days. Checkpoint first, 271. HR 0.32. The order matters: priming before checkpoint release more than doubled median survival. Across the class, a 2024 meta-analysis of seven dendritic cell vaccine trials, 3,619 patients, found HR 0.71 for survival, "indicating a true-positive result." Related indication: the FDA's own example is "a different stage of the same disease." DCVax-L worked at both stages. Independent natural history: national cancer registries, separate from the trial controls, as the guidance requires. Real-world data is expressly allowed. ๐—ง๐—ต๐—ฒ ๐—ฝ๐˜‚๐—ฏ๐—น๐—ถ๐˜€๐—ต๐—ฒ๐—ฑ ๐—ฐ๐—ฟ๐—ถ๐˜๐—ถ๐—ฐ๐—ถ๐˜€๐—บ๐˜€, ๐—ฎ๐—ป๐˜€๐˜„๐—ฒ๐—ฟ๐—ฒ๐—ฑ Three published critiques set out the case against the trial. Each point, answered from the record: Endpoint switched to survival? Progression could not be read: 256 of 494 scans needed adjudication. The critics agree: progression-free survival "is not an adequate endpoint for immunotherapy studies because of the phenomenon of pseudoprogression." Survival is the "gold standard," in their words. Cohort-level controls? The critics named the fix: propensity score matching or inverse probability weighting on patient-level data. That is exactly what 2026 did, and the benefit grew. Never validated in GBM? Two of the critics who raised it led the 2026 study showing patient-level external controls reproduce randomized results. Selection? Dropping the control trials that admitted early progressors changed nothing, as above. The benefit was larger in patients with more residual tumor, the opposite of what selection would produce. IDH, a tumor mutation linked to longer survival? Tested centrally in every DCVax-L patient. The gap is in the older control trials. Chosen after the fact? An independent firm, prespecified criteria, validation as above. Then a larger effect against different trials at the patient level. Company author? Data held by independent CROs, analyzed by independent statisticians. Run another trial? The completed program, crossover and survival evidence make a repeat unnecessary; the FDA's guidance names the ethical concern; the BLA documents why a new randomized design is not feasible or ethical. ๐— ๐—ฎ๐—ป๐˜‚๐—ณ๐—ฎ๐—ฐ๐˜๐˜‚๐—ฟ๐—ถ๐—ป๐—ด The framework also requires that the product "can be manufactured to regulatory quality standards." DCVax-L was made for every patient in a 94-site phase 3, and in 2023 the UK regulator licensed the Sawston facility for commercial manufacturing, with products that "may be exported globally." A UK license is not US approval: FDA inspection and the potency assay go on the table at the pre-BLA meeting. ๐—•๐—ฒ๐—ป๐—ฒ๐—ณ๐—ถ๐˜ ๐—ฎ๐—ป๐—ฑ ๐—ฟ๐—ถ๐˜€๐—ธ Longer survival in a disease with no proven alternative at recurrence. 2,151 doses, 5 serious events even possibly related, no autoimmunity, no cytokine storm. It is the patient's own immune system, with one broken link rebuilt. A repair, judged the way a repair should be judged. ๐—ง๐—ฟ๐—ฒ๐—ฎ๐˜๐—ถ๐—ป๐—ด ๐—ฝ๐—ฎ๐˜๐—ถ๐—ฒ๐—ป๐˜๐˜€ ๐˜„๐—ต๐—ถ๐—น๐—ฒ ๐˜๐—ต๐—ฒ ๐—™๐——๐—” ๐—ฟ๐—ฒ๐˜ƒ๐—ถ๐—ฒ๐˜„๐˜€ Right to Try covers a product that has completed phase 1, is in active development and not on hold, and has an application on file. Filing the BLA satisfies the application condition; the others must still hold at that time. Patients must have a life-threatening disease, have exhausted approved treatments, be unable to join a trial and consent, and the manufacturer must choose to provide it. No separate FDA approval of each case. Build the program before filing. An expanded access treatment protocol (21 CFR 312.320) requires completed trials, active pursuit of approval and phase 3 evidence. The trials are complete and the phase 3 is published, so it does not have to wait for the BLA. Treatment can begin 30 days after the FDA receives the protocol, absent a hold. The usual reason a manufacturer holds back is risk: a serious event in a very sick patient gets blamed on the product. The FDA answered that in its April 2026 guidance: it "does not intend to deny, delay, or refuse to approve" a BLA "based solely on an adverse event occurring in the context of expanded access use," and "is not aware of any instances" where one prevented approval. Access is the bridge. Approval is the destination. This is not new for DCVax-L: it has been provided under Germany's hospital exemption and the UK Specials pathway. ๐—ฆ๐—ฒ๐—ฒ๐—ธ ๐˜๐—ฟ๐—ฎ๐—ฑ๐—ถ๐˜๐—ถ๐—ผ๐—ป๐—ฎ๐—น ๐—ฎ๐—ฝ๐—ฝ๐—ฟ๐—ผ๐˜ƒ๐—ฎ๐—น, ๐˜„๐—ถ๐˜๐—ต ๐—ฎ ๐—ฝ๐—ฟ๐—ผ๐˜€๐—ฝ๐—ฒ๐—ฐ๐˜๐—ถ๐˜ƒ๐—ฒ๐—น๐˜† ๐—ฑ๐—ฒ๐˜€๐—ถ๐—ด๐—ป๐—ฒ๐—ฑ ๐—ฟ๐—ฒ๐—ด๐—ถ๐˜€๐˜๐—ฟ๐˜† The framework's guidance: approval is traditional or accelerated "depending on the endpoints used." Survival is the endpoint, so the request is traditional, full approval, with no confirmatory-trial requirement. The FDA can still require postmarketing studies, and the framework's authors named the tool: "collecting real-world evidence to confirm continued preservation of efficacy." A registry of every treated patient, designed before approval. If accelerated approval becomes the route, the regenerative medicine advanced therapy (RMAT) statute lets post-approval requirements be met through registries and "postapproval monitoring of all patients treated with such therapy prior to approval." Every patient treated under Right to Try or expanded access counts. ๐—ช๐—ต๐—ฎ๐˜ ๐—ต๐—ฎ๐—ฝ๐—ฝ๐—ฒ๐—ป๐˜€ ๐—ป๐—ฒ๐˜…๐˜ Northwest has pursued the UK first. Its application there has been under review since late 2023, and in July 2026 the UK regulator confirmed it "remains under its initial regulatory review, has not been refused." The US filing is the step that remains. 1. Publish the patient-level reanalysis. 2. Lock in the patient-level control data rights the FDA requires. 3. Report the central IDH results and publish the phase 3 immune data. 4. Request RMAT designation now. FDA must answer within 60 days. 5. File the treatment protocol and build the Right to Try program. 6. Pre-BLA meeting with CBER: plausible mechanism review, six external-control tests answered, manufacturing and potency package. 7. File the BLA with priority review. 8. Build the registry. Approving DCVax-L this way would be the framework's proof beyond genetic disease: an individualized cell therapy, aimed at the root cause of the deadliest brain cancer, carried by a completed phase 3. A win for patients first. ๐—ง๐—ต๐—ฒ ๐˜๐—ฟ๐—ถ๐—ฎ๐—น ๐—ถ๐˜€ ๐—ฑ๐—ผ๐—ป๐—ฒ. ๐—ง๐—ต๐—ฒ ๐—ณ๐—ฟ๐—ฎ๐—บ๐—ฒ๐˜„๐—ผ๐—ฟ๐—ธ ๐—ถ๐˜€ ๐˜„๐—ฟ๐—ถ๐˜๐˜๐—ฒ๐—ป. ๐—ง๐—ต๐—ฒ ๐—ฝ๐—ฎ๐˜๐—ถ๐—ฒ๐—ป๐˜๐˜€ ๐—ฎ๐—ฟ๐—ฒ ๐˜„๐—ฎ๐—ถ๐˜๐—ถ๐—ป๐—ด. ๐—ช๐—ต๐—ฎ๐˜ ๐—ถ๐˜€ ๐—น๐—ฒ๐—ณ๐˜ ๐—ถ๐˜€ ๐˜๐—ผ ๐—ฎ๐˜€๐˜€๐—ฒ๐—บ๐—ฏ๐—น๐—ฒ ๐—ถ๐˜ ๐—ฎ๐—ป๐—ฑ ๐—ณ๐—ถ๐—น๐—ฒ. Disclosure: long $NWBO. Commentary on published and presented data and public FDA documents. Not medical, legal, regulatory or investment advice. DCVax-L is investigational and not approved in the US. Regulatory strategy is the sponsor's decision.

Andrew Caravello, DO

49,800 Aufrufe โ€ข vor 15 Tagen

Donald J. Trump You are just another puppet for the globalist Zionist Rothschild bankers who control America, just like the other presidents before you. You are just another war criminal and traitor to humanity. You don't care about America; you care more about the elite and Israel than you do about American citizens. You're nothing but a con man. You're the most pro-Israel president there ever was. If you win this election, youโ€™re going to keep simping for Israel just like the other presidents before you. Youโ€™re not America first; youโ€™re Israel first and the New World Order first. Trump, you go on about how you're for freedom of speech, but you recently said you will deport anti-Israel protesters if elected, which is super unconstitutional. Plus, when youโ€™re in office, you will push to go to war with Iran because your masters will tell you to, so you can help them take Iranโ€™s central bank and make their Greater Israel project. You will continue the genocide against Palestinians, which needs to stop, and push for war with China. Youโ€™ll continue the red scare propaganda and all that other nonsense. Not to mention, youโ€™re a massive shill for Big Pharma. Also, one of the Supreme Court justices you appointed ruled that presidents have immunity from prosecution for official acts in office, marking the biggest government power grab since the Act of 1913, transforming America from a corporate empire to a corporate empire monarchy. So much for being America First ๐Ÿ‘‡ Things Trump did that prove he's just another puppet to the elite: 1. Gave Fauci a Presidential Commendation Award 12 hours before he left office. 2. Operation Warp Speed that killed so many people. 3. Printed $8T in one term. 4. Signed CISA into law, which created the government backdoor censorship infrastructure into social media. 5. He's the most pro-Israel president ever. 6. Lockdowns that cost America $16T. 7. Never locked up Hillary. 8. Brought the swamp into the White House: Pompeo, Bolton, Kushner, etc. 9. Made sure 600 billionaires increased their wealth by $2.3T during the โ€œpandemic.โ€ 10. Zero liability for pharma. 11. Didn't fire Fauci. 12. Jeff Sessions. 13. FBI Director Wray. 14. Appointed war criminal John Bolton as the National Security Director. 15. Section 230 immunity. 16. Continued Israel's genocide against Palestinians. 17. Killed Soleimani and wanted to go to war with Iran. 18. Wanted to invade Venezuela. 19. Did nothing to end the Federal Reserve. 20. Armed the neo-Nazis in Ukraine, just like other presidents did. 21. Recognized Israelโ€™s sovereignty over the occupied Golan Heights, which it captured from Syria in 1967. Israel annexed the Golan in 1981 in a move not recognized internationally, but Trump pretty much gave Israel the Golan Heights. 22. Appointed a Big Pharma executive connected to Bill Gates to head vaccine developments. 23. Imposed unlawful sanctions on countries, which killed a lot of people, just like other presidents did. 24. Organized a coup in Bolivia and wanted to send the military to Venezuela. 25. In just 3 years of his presidency, Trump dropped 72,000 bombs, following in his predecessors' footsteps. 26. In 2020, Trump launched more airstrikes on Somalia than Bush & Obama combined. 27. Said in 2023 that he would use โ€œSection 212(f) of the Immigration and Nationality Actโ€ to โ€œorder my government to deny entry to all communists and Marxists,โ€ which is unconstitutional. 28. In just the first 9 months of his presidency, he dropped more bombs on civilians than Obama and Bush. 29. Dropped the mother of non-nuclear bombs on Afghanistan. 99 Times Trump Supported the Evil State of Israel ๐Ÿ‘‡๐Ÿ‘‡ 1. President Trump recognized Jerusalem as the capital of Israel. 2. President Trump moved the American Embassy to Israel from Tel Aviv to Jerusalem. 3. President Trump closed the Jerusalem consulate and made it an Embassy branch. 4. President Trump has never publicly criticized Israel. 5. President Trump pulled America out of the Iran deal. 6. President Trump raised military aid to Israel by $400 million. 7. President Trump imposed sanctions on Iran as soon as he pulled out of the deal. 8. President Trump recognized Israel's sovereignty over the Golan Heights. 9. President Trump designated the IRGC (Iranian special forces) as a foreign terrorist group. 10. President Trump banned BDS head Omar Barghouti from America. 11. President Trump banned the head of the ICC and its staff from coming to America. 12. President Trump backed Israelโ€™s right to self-defense in Gaza. 13. President Trump left the United Nations Human Rights Council. 14. President Trump cut off all aid to the Palestinian Authority. 15. President Trump closed the PLO office in Washington, D.C. 16. President Trump was the first president to visit the Western Wall as President. 17. President Trump sent the first official American visit to the Western Wall with an Israeli Prime Minister. 18. President Trump allowed consulate and Embassy staff to meet with Jews of Judea and Samaria. 19. President Trump allowed consulate and Embassy staff to visit Jews living in Judea and Samaria. 20. President Trump announced that America would not support Israeli soldiers being tried at the ICC. 21. President Trump called out the anti-Israel antisemitism of Ilhan Omar. 22. President Trump flew to Israel on his first foreign trip. 23. President Trump issued no waivers on increased sanctions against Iran. 24. President Trump offered a $10 million reward for information on Hamas and Hezbollah financial networks. 25. The Trump administration wrote op-eds blaming Hamas and the Palestinians for the Israeli-Palestinian conflict. 26. President Trump stopped the lame-duck last-minute Kerry and Obama $221 million payment to the Palestinian Authority on January 20, 2017. 27. President Trump signed the Taylor Force Act. 28. President Trump supported Israel in the May 2019 flare-up with Gaza. 29. President Trump refused a visa to Israel hater Hanan Ashrawi to America. 30. President Trump sanctioned three leading members of Hezbollah in July 2019. 31. The Trump administration blocked an attempt to get the UN Security Council to issue a formal condemnation of Israelโ€™s demolition of Palestinian homes on the edge of Jerusalem in July 2019. 32. President Trump sanctioned Iranian Foreign Minister Mohammad Javad Zarif. 33. Ambassador Friedman refused to advocate for a two-state solution unfavorable to Israel. 34. President Trump removed โ€œPalestineโ€ from the list of countries on the State Department list of nations. 35. President Trump stopped a French $15 billion credit line to Iran. 36. President Trump stopped a UN Security Council statement on tensions between Israel and Hezbollah that did not single out violence by the Lebanese terror group. 37. President Trump cut $120 million from aid to Lebanon to ensure it didnโ€™t get to Hezbollah. 38. President Trump sanctioned 9 Iranians in November 2019. 39. President Trump supported Israel after rocket fire in its skirmish with Islamic Jihad. 40. President Trump said nothing about Israel limiting retaliation. 41. President Trump and America were the only countries besides Israel to vote against all 8 UN 4th committee resolutions in November 2019. 42. President Trump declared that Jewish towns in Judea and Samaria (โ€œsettlementsโ€) arenโ€™t illegal under international law. 43. President Trump hasnโ€™t supported a two-state solution as the only solution in the Israeli-Palestinian conflict. 44. Vice President Pence visited Israel during his first year in office. 45. Secretary Pompeo wrote a letter to Congress clarifying that Jewish towns in Judea and Samaria have traditionally enjoyed bipartisan support. 46. Secretary Pompeo says that claims that Jewish towns in Judea and Samaria have impeded peace are foolish. 47. President Trump didnโ€™t comment when Defense Minister Bennet green-lighted a new Jewish neighborhood in Hebron. 48. Secretary Pompeo announced that Iran is behind all the unrest in the Middle East. 49. President Trump blamed Iran for Lebanon protests. 50. President Trumpโ€™s US deputy national security adviser Victoria Coates reportedly met with envoys from UAE, Oman, Morocco, Bahrain to gauge willingness for Israeli-Arab non-belligerence agreements. 51. President Trump denounced Iran's brutal crackdown on protesters. 52. New US Ambassador to the United Nations Kelly Craft said sheโ€™ll defend Israel. In her first United Nations press conference, Kelly Craft also warned Iran that Washington has โ€˜other toolsโ€™ if Tehran continues its bad behavior. 53. President Trump regaled an Israeli-American group with tales of his pro-Israel moves, retelling an extensive account of the embassy move and telling the Israeli American Council that heโ€™s Israelโ€™s best friend in the White House. 54. President Trump signed an executive order on anti-Semitism that protects Jewish students on college campuses. The order includes anti-Israel activity. 55. Robert Oโ€™Brien told Meir Ben-Shabbat that โ€˜common interests between Israel and Arab statesโ€ฆ have made new regional partnerships possible to counter Iran.โ€™ 56. The Trump administration denounced Iranian human rights abuses and imposed sanctions on Iranian judges. 57. After President Abbas hailed the ICC declaration that it will investigate Israel as a historic day for Palestinians, Secretary Pompeo said the US โ€˜firmly opposesโ€™ the ICC announcement on alleged Israeli war crimes. He said the International Criminal Courtโ€™s move โ€˜unfairly targetsโ€™ the Jewish state and called for direct negotiations between Israel and the Palestinians. 58. The Trump administration announced seven joint US-Israeli clean energy projects โ€” including an energy-storing system for electric cars and a hydrogen-powered drone that takes off vertically โ€” have received $6.4 million in funding from the US-Israel Binational Research and Development Program for energy. 59. America struck an Iranian-backed militia in Iraq; 19 reported killed. Israeli Air Force chief said, โ€˜US strike on Iran-backed Iraqi militia is a โ€˜potential turning point.โ€™ 60. President Trump ordered a deadly strike on Iranโ€™s Soleimani. 61. President Trump said new Iran sanctions have been imposed; they are strong and powerful. 62. President Trump said โ€˜Iran will never have nuclear weapons.โ€™ 63. Vice President Pence and PM Netanyahu met in Jerusalem. 64. President Trump and PM Netanyahu announced that heโ€™ll reveal the Middle East peace plan next week. 65. Trumpโ€™s Middle East Peace Plan favors Israel. 66. PM Netanyahu to US President Donald Trump in the Oval Office: โ€œYour Deal of the Century is the opportunity of the century.โ€ 67. President Trump, in the White Houseโ€™s East Room, said Israel is taking a โ€˜giant step toward peace.โ€™ 68. President Trump unveiled his Middle East peace plan, saying that Israel will keep Jerusalem, while the Palestinians will have their capital in eastern Jerusalem. 69. President Trump lauded Netanyahu for backing the deal, and it โ€˜demonstrates the enormous progress weโ€™ve made.โ€™ 70. President Trump said, โ€˜We will not allow a return to the days of bloodshed, bus bombings, nightclubs.โ€™ 71. President Trump said the US will recognize all existing Israeli towns in Judea and Samaria. 72. President Trump released a map of Israelโ€™s future borders under his peace plan. 73. President Trump said, โ€˜We are asking the Palestinians to meet the challenges of peaceful coexistence.โ€™ 74. US Ambassador to Israel David Friedman said Jewish settlements in Judea and Samaria are part of Israel. 75. President Trumpโ€™s Middle East Peace Plan reportedly green-lighted an arms sale to the United Arab Emirates. 76. President Trump hosted the signing ceremony for Israel to normalize relations with UAE and Bahrain. 77. President Trump hosted the Israeli Prime Minister and Foreign Ministers of the United Arab Emirates and Bahrain at the signing of the Abraham Accords. 78. President Trump tweeted, โ€˜More countries will come into the tent!โ€™ 79. President Trump praised Sudan for agreeing to a peace deal with Israel. 80. President Trump announced that the US lifted Sudanโ€™s state sponsor of terrorism designation. 81. The Trump administration secretly moved large quantities of arms to Israel just after the 1973 Middle East War, well beyond what was being sent through official channels. 82. President Trump said, โ€˜There are five more countries that want to sign onto peace deals with Israel.โ€™ 83. President Trump brokered a peace deal between Israel and Sudan. 84. President Trump signed legislation to create a fund to encourage collaboration between the US and Israel in creating cutting-edge defense technologies. 85. President Trumpโ€™s administration announced that any goods made in Israeli communities in the West Bank and exported to the United States should be labeled as โ€˜Made in Israelโ€™ or โ€˜Product of Israel.โ€™ 86. President Trumpโ€™s administration imposed more sanctions on Iran. 87. President Trumpโ€™s administration added an Iran-aligned Bahraini group to its terrorist blacklist. 88. President Trump said, โ€˜Israel and Morocco have agreed to full diplomatic relations โ€“ a massive breakthrough for peace in the Middle East!โ€™ 89. President Trump issued an order allowing American citizens born in Jerusalem to have Israel listed on their passports. 90. President Trumpโ€™s administration sold 50 F-35 fighter jets to the United Arab Emirates. 91. President Trumpโ€™s administration signed an agreement with Israel to protect each otherโ€™s technology and intelligence from Chinese influence. 92. President Trump brokered a peace deal between Israel and Morocco. 93. The Trump administration sold Israel 50 F-35 fighter jets. 94. President Trump announced that Israel and Bhutan agreed to establish diplomatic relations. 95. President Trumpโ€™s administration provided $12 million to enhance Israelโ€™s missile defense systems. 96. President Trumpโ€™s administration imposed new sanctions on Iran in a last-minute push aimed at Iran. 97. President Trumpโ€™s administration negotiated a normalization of relations between Israel and Morocco. 98. President Trump said it was an honor to broker a peace deal between Israel and Morocco. 99. President Trump delivered a Middle East Peace Plan that favored Israel. It does not matter who you vote for, whether it's Trump or Biden. America is occupied territory, and the only way the country can change is if it has a true reset, free from the bankers, lobbyists, and Zionist globalist elites that have controlled America since 1871. #DonaldTrump #Trumpisaconman #FreePalestine #Zionism #TrumpCrimeFamily #Israel

Welsh Republic Podcast

61,945 Aufrufe โ€ข vor 2 Jahren

dave meltzer: youtube enthusiast ๐Ÿ’€ perfect. now we can stop pretending this was ever complicated. the real story is not that wwe is afraid of aew. the real story is not that โ€œhigh level wwe officialsโ€ are whispering scary things to dave meltzer. the real story is not even that tony khan got asked a planted question on a media call with very little distribution about the possibility of aew soon having very little distribution, although that sentence is so stupidly perfect it should be bronzed and placed outside the wrestling observer newsletter office like a war memorial for people who died pretending this was journalism. the real story is that aew is going to lose its wbd distribution deal. either it ends at the expiration of the three-year term in 2027, or it ends earlier if paramount closes wbd and decides aew has no strategic place inside the new company. and based on the board as it exists right now, the most likely landing spot for aew in 2027 is google / youtube. that is the story. everything else is laundering. tony khan wants the story to be: โ€œwhy would wwe say this about us?โ€ that is the whole operation. take my public analysis. run it through dave meltzer. assign it to wwe / tko. then let tony khan answer a canned question on a media call with very little distribution about potentially having very little distribution. a media call for a lightly viewed roh show. a planted story. a planted messenger. a rehearsed answer. a pr flack probably wrote it. tony khan performs hurt. tony khan says โ€œi donโ€™t know why wwe wouldโ€ฆโ€ tony khan denies the obvious. tony khan keeps me minimized. tony khan removes me from the public conversation about the exact thing i have repeatedly said is going to happen to aew. everyone is supposed to pretend this is organic. it is not. it is the most bubble wrapped, manufactured, artificial environment possible. aew is heading toward youtube because the domestic media rights board is closing around them. not as a troll. not as a bit. not as โ€œpr spin.โ€ as a business conclusion. aew is not leverage. wwe is not afraid of aew. the $185 million number was bullshit. the buyer universe was shrinking. paramount / skydance was coming for wbd. wbd was not going to be some permanent aew safe house. youtube was only ever a real โ€œoptionโ€ if someone at google was actually cutting a media rights check and underwriting production. not because every divorced mom with a ring light and a gmail account can upload video to the same platform. that was always the distinction. that is still the distinction. Nick LoPiccolo โ€” February 28, 2025 โ€œYouTube is an option the same way you or I could start a YT channel tomorrow. Is Jon Cruz cutting AEW a media rights check or underwriting a production budget? Hell no. Just the reality. It isnโ€™t the model. Jon is global head of sports over there.โ€ that was february, not last week. not after dave meltzer suddenly discovered youtube prelim numbers like columbus finding the new world. it is becoming inevitable now. Nick LoPiccolo โ€” April 30, 2026 โ€” 11:26 AM โ€” 251.2K Views โ€œto every journalist and every podcast who interviews tony khan from this day forward: please ask tony if wbd told him back in august they would not be renewing aew. wbd told him in august. i confirmed it directly and triple sourced it. please ask why tony has been acting like nothing is wrong for the last 8 months, and then please ask tony what his actual distribution plan is. because the only distributor left that will take aew is google/youtube. the myaew app is not realistic. the my aewapp is a death sentence in 2026 if youtube doesnโ€™t make an mg deal for aew. they started building it too late and there is no realistic way to scale it. also, who is going to sell ads for the platform? kiswe is not the best. they built the myaew app. they are new to the game. hold tonyโ€™s feet to the fire. Paramount is not real for aew. WBD passed back in August. CW/Roku is now off the table. Amazon and Fox do not want AEW. ask Tony why he's been lying to you and to the locker room and to the fans, acting like things are all great with the network? i am sure a lot of people would love to hear his answer.โ€ april 30. 251.2k views. not whispered. not hidden. not vague. not โ€œhigh level wwe officials.โ€ i said it publicly and directly: wbd passed back in august. paramount is not real for aew. cw / roku is off the table. amazon and fox do not want aew. the myaew app is not realistic. google / youtube is the only distributor left on the board that makes sense. that is the actual story tony khan does not want to answer. not โ€œwhy would wwe say this?โ€ ask tony khan if wbd told him in august that wbd would not be renewing aew. ask what his actual distribution plan is. ask who is selling ads for the myaew app. ask how a platform built this late scales in 2026. ask whether youtube is an actual rights partner with an mg, or just the place you go when the real buyers are gone. that is the question. not the fake question dave meltzer laundered into โ€œhigh level wwe officials.โ€ the real question. Nick LoPiccolo โ€” July 9, 2025 โ€” 10:51 AM โ€” 9,565 Views โ€œNo one in Hollywood believes the $185 million number.โ€ Nick LoPiccolo โ€” July 9, 2025 โ€” 11:35 AM โ€” 7,470 Views โ€œThe $185 million figure is inflated. Varietyโ€™s October 2, 2024 article was likely updated after a publicist called on AEWโ€™s behalf, as early reports placed the deal between $140 and $150 million per year. Tony Khan was also included in Varietyโ€™s Dealmakers 2024 list, which, while not officially pay to play, strongly favors those spending significant advertising dollars with the outlet. No one in Hollywood seriously believes WBD, which is in junk bond status, is paying AEW $185 million per year. Clear enough?โ€ clear enough? the number was never clean. the number was never real in the way aew fans and wrestling media pretended it was real. and when the $185 million number started getting laughed out of adult rooms, the number magically became $178 million. that is where the shell game gets funny. because $178 million was not some sacred sourced number either. it was brandon thurston taking the median between $170 million, reported by sports business journal, and $185 million, reported by variety and others. that is literally what wrestlenomics said. Wrestlenomics โ€” October 4, 2024 โ€œWhy use $178 million here for AEWโ€™s new deal when some outlets are reporting the average annual value is $185 million?โ€ Wrestlenomics โ€” October 4, 2024 โ€œI used $178 million here because it is simply the median of $170 million, as reported by Sports Business Journal, and $185 million, reported by Variety and others.โ€ there it is. arithmetic. not an all-cash rights fee. not a clean license number. not proof wbd valued aew like raw. not a finance-department document from warner bros. discovery. a midpoint between conflicting public reports. then wrestling media treated that midpoint like scripture because they needed the story to be โ€œaew is valued like raw,โ€ not โ€œaew pr inflated a number no serious person in hollywood believed.โ€ and by the way, $170 million was not the clean all-cash number either. that is the scam. float the number. repeat the number. launder the number. defend the number with people who do not understand the difference between cash rights fees, in-kind services, equity, marketing commitments, platform value, make-goods, ad inventory, and press release math. then when the number collapses, pretend the next number was always the number. that is not reporting. that is aew state news. Nick LoPiccolo โ€” July 10, 2025 โ€” 5:53 AM โ€” 12.6K Views โ€œAEW isnโ€™t leverage. Itโ€™s not competition. Itโ€™s a niche product with loud fans and limited reach.โ€ Nick LoPiccolo โ€” July 10, 2025 โ€” 8:56 AM โ€” 1,018 Views โ€œWe handle wrestling deals too, but thinking we need AEW for leverage is myopic. The landscape is changing and the game Iโ€™m playing is different.โ€ Nick LoPiccolo โ€” July 15, 2025 โ€” 25.7K Views โ€œAEW isnโ€™t leverage.โ€ that was never emotional. that was never tribal. that was never โ€œi hate aew.โ€ it was market structure. wwe did not need aew as leverage because real leverage was never โ€œanother wrestling show exists.โ€ real leverage is architecture, scale, subscriber churn, platform strategy, sports adjacency, global rights, advertising, sponsorship, live inventory, library value, data, brand safety, executive relationships, and the actual buyer universe of maybe 18-20 companies in the united states that matter for live sports rights. aew fans thought this was a wrestling argument. it was never a wrestling argument. it was a board. and the board was already moving. Nick LoPiccolo โ€” August 11, 2025 โ€” 482 Views โ€œI wasnโ€™t viewing the above in that context (TKO vs AEW counter programming), it was more of this is what Iโ€™m hearing after 2 weeks of big media deals rolling out (Skydance closing, South Park library moving) etc. Which have all been in the works for awhile.โ€ Nick LoPiccolo โ€” August 11, 2025 โ€” 388 Views โ€œBut if you were to look at it from a counter programming perspective (and I donโ€™t think this was a factor in UFC deal) - there are only so many players for these big media rights deals. PARA is likely off the board (via TKO deal) & then what if they acquire WB in 2026/27?โ€ Nick LoPiccolo โ€” August 11, 2025 โ€” 535 Views โ€œYes, of course, that wouldnโ€™t mean the end for AEW. It would make navigating their media rights deal more challenging, I would guess. But this is a hypothetical scenario & I do not believe anyone is paying $7.7b for UFC or a $40b valuation for WB w/ how do we fuck AEW, either.โ€ Nick LoPiccolo โ€” August 11, 2025 โ€œAnd hearing all weekend Paramount is still interested in WBD.โ€ Nick LoPiccolo โ€” August 11, 2025 โ€” 1.3K Views โ€œI think more interesting for what it could mean as the dominoes keep falling in terms of the still evolving landscape. The deals are massive & the number of major players at the top are shrinking as still big push for consolidation & scale.โ€ Nick LoPiccolo โ€” August 11, 2025 โ€” 12:11 PM โ€” 2,588 Views โ€œAnd Iโ€™d view AAA on Google/YouTube as directly competitive. It targets both the CMLL collab & the audience that used to watch AEW Dark on YouTube, & WWE is able to send well known stars to AAA events with an eye towards converting more of the younger, YouTube demo of viewers who donโ€™t watch streamers.โ€ again: august 11. not yesterday. not after dave meltzer tweeted a netflix prelim number. not after anyone had to retrofit the argument. the point was already there: the major players at the top were shrinking, paramount was still interested in wbd, paramount was likely off the board for aew because of the tko deal, google / youtube was becoming directly competitive for the exact audience aew used to reach through dark, and the buyer universe was consolidating around deals much bigger than tony khanโ€™s feelings. this was not mysticism. this was not inside baseball for the sake of sounding smart. this was the board. Nick LoPiccolo โ€” August 24, 2025 โ€œThis isnโ€™t fair. I misread your question. AEW will exist but likely on the Discovery Global app (if it ever launches, I would bet that it doesnโ€™t) and it will continue to do consistent ratings. If Paramount/Skydance buys WBD in a yearโ€ฆโ€ Nick LoPiccolo โ€” September 4, 2025 โ€” 76 Views โ€œNo, thatโ€™s the WBD network division (cable, news, sports) that was already announced as being spun off under Discovery Global. The article youโ€™re citing is about them selling a minority equity stake in that unit to cut debt and boost valuation ahead of the 2026 split.โ€ Nick LoPiccolo โ€” September 16, 2025 โ€” 3.6K Views โ€œThis is not just about Hollywood scale. It is the foundation of a conservative aligned media infrastructure. A Paramount/WBD merger would fold CBS, CNN, HBO, and Warner Bros IP into Ellisonโ€™s orbit under Trumpโ€™s regulatory umbrella.โ€ Nick LoPiccolo โ€” September 16, 2025 โ€” 11K Views โ€œWithin 48 hours of the rumor, WBD stock surged ~55% and Paramount Skydance rose ~24%. That market response itself boxed David Zaslav in; his board, Wall Street, and his own contract now expect movement.โ€ Nick LoPiccolo โ€” September 27, 2025 โ€” 12:16 PM โ€” 3,516 Views โ€œNah homie. Enjoy watching the show on YouTube after Ellison buys WBD and Ari who is advising Ellison and used to represent Trump and runs TKO makes the call.โ€ Nick LoPiccolo โ€” September 28, 2025 โ€” 174 Views โ€œI believe if and when Paramount acquires WBD, TKO will push to lock down a monopoly on combat sports. The long knives are already out for competitors, and the rights deals have likely been spread around town precisely to keep rivals from signing with those streamers.โ€ none of that was random. paramount / skydance, ellison, ari, tko, wbd linear assets, youtube, aaa, the tko deal, the wbd split, the shrinking rights buyer universe โ€” all of it was one connected domestic rights architecture. that is why this conversation was always over the heads of the people screaming โ€œcopeโ€ in my replies. they were arguing like fans. i was reading the cap table. Nick LoPiccolo โ€” December 6, 2025 โ€” 3:07 PM โ€” 41.4K Views โ€œYes, I always believed Paramount would walk away with WBD. I was one of the first to talk about it on here, even if I wasnโ€™t the first to hear it. The Paramount Skydance acquisition closed on August 7. I posted this on August 11, about 1 month before the The Wall Street Journal first broke the news on September 12 that Paramount Skydance was preparing a bid for WBD.โ€ Nick LoPiccolo โ€” December 6, 2025 โ€” 3:07 PM โ€” 41.4K Views โ€œThe bid was always going to be hostile. We are only in this process because it was a hostile bid. Most people in Hollywood believed Ellison long coveted WB and Jack Warnerโ€™s chair. WB was not for sale when Skydance acquired Paramount, which is much smaller in scale.โ€ Nick LoPiccolo โ€” December 6, 2025 โ€” 3:07 PM โ€” 41.4K Views โ€œNearly everyone in town assumed an Ellison acquisition of WBD was inevitable until the Netflix bid shocked everyone. Signs were there for the last two weeks, which is also when I stopped posting about what might happen. Of course, its not over yet. Paramount still has paths to winning this acquisition. The one thing thatโ€™s for certain though is an Ellison-led acquisition of WBD is no longer inevitable.โ€ Nick LoPiccolo โ€” December 8, 2025 โ€œEND CREDITSโ€ space jam is a warner bros. movie. that was the joke. and the joke was the same thing i had been saying the whole time: paramount was winning the bid, for those who did not understand. Nick LoPiccolo โ€” December 19, 2025 โ€” 4:30 PM โ€” 828 Views โ€œHere is another reference to it. So tell me how exactly is Paramount the better outcome for Daveโ€™s argument? Netflix doesnโ€™t touch the WBD linear assets. Gunnar keeps his SpinCo.โ€ Puck excerpt โ€” December 19, 2025 โ€œMany industry insiders are also skeptical about Paramountโ€™s seven-year, $7.7 billion deal for exclusive UFC rights in the U.S. Yes, it can be read as a signal that Ellison came to play. But some people see it more as Ari Emanuel having his way with the person to whom he is ostensibly an (unpaid) advisorโ€ฆโ€ that is the board. that is the relationship map. that is the thing wrestling media either does not understand or pretends not to understand, because understanding it means admitting the story is not โ€œaew has leverage.โ€ the story is that aew is sitting in the middle of a consolidating rights marketplace where the people with leverage are doing much bigger things than worrying about tony khanโ€™s feelings. Nick LoPiccolo โ€” January 21, 2026 โ€” 4:22 PM โ€” 870 Views โ€œi mean get ready to learn youtube buddyโ€ Nick LoPiccolo โ€” February 19, 2026 โ€” 2.8K Views โ€œParamount was always my bet to acquire Warner Bros. Never wavered.โ€ Nick LoPiccolo โ€” February 28, 2026 โ€” 1:27 PM โ€” 118 Views โ€œyou donโ€™t need to look under a hood I AM SAYING THE QUIET PART OUT LOUD ๐Ÿšจ๐Ÿšจ๐Ÿšจ๐Ÿšจ๐Ÿšจ I BEEN SAYING IT SINCE JULY / AUGUST ๐Ÿšจ๐Ÿšจ๐Ÿšจ๐Ÿšจ๐Ÿšจ PARAMOUNT IS COMING FOR WBD AEW WILL LOSE A TV DEAL ๐Ÿšจ๐Ÿšจ๐Ÿšจ๐Ÿšจ๐Ÿšจ GUESS WHO WAS RIGHT ๐Ÿ’€โ€ so no, this is not hindsight. this is not showing up after the fact with a flashlight and pretending i discovered the body. this is a paper trail. february: youtube is not a real rights model unless google is cutting the check. april: wbd passed back in august, the myaew app is not realistic, paramount is not real for aew, cw / roku is off the table, amazon and fox do not want aew, and google / youtube is the only distributor left that makes sense. july: the $185 million number is inflated and aew is not leverage. august: the buyer board is shrinking, paramount is still interested in wbd, and google / youtube becomes directly competitive. september: paramount / wbd folds the board into ellisonโ€™s orbit, and if ellison buys wbd, enjoy youtube. december: paramount was always the bet, the bid was always going to be hostile, and netflix does not solve dave meltzerโ€™s argument because netflix does not touch the linear assets. january: get ready to learn youtube. february: paramount is coming for wbd and aew will lose a tv deal. same board. same thesis. same answer. now here is the part tony khan and dave meltzer do not want to say out loud. tony khan and dave meltzer do not mention me publicly for a reason. because the second they say my name out loud, they admit where this conversation has actually been coming from. not wwe. not some anonymous โ€œhigh level official.โ€ not some shadowy tko whisper campaign. me. that is the problem for them. behind the scenes, ask any real insider what happens when my name comes up around this subject. there is a reaction. not because iโ€™m magic. not because iโ€™m some internet boogeyman. because they know exactly who is saying it, why iโ€™m saying it, what rooms i have been in, what companies i have dealt with, what executives i have spoken to, and why the analysis keeps landing. that is why they keep trying to non-person me publicly while reacting to me privately. they want the argument. they want the benefit of responding to the argument. they just do not want to admit whose argument it is. when i said wbd told aew back in august 2025 they were not exercising the option for the fourth year, tony khan blew up behind the scenes and forced john mcmullen to revise / update his article 2-3 weeks ago after i tweeted it. which is hilarious because that should not even be crazy or damaging โ€œnews.โ€ that is how this business works. when a distributor is not continuing, they tell you early enough so you have time to find a new home. that is not sabotage. that is not wwe. that is not nick lopiccolo hiding inside david zaslavโ€™s air vents with a clipboard. that is corporate courtesy. wbd execs privately whisper and shake their heads at tony khanโ€™s behavior because their view is very simple: why does tony khan act like everything is great and rainbows and sunshine with the studio? we told tony khan as a courtesy so tony khan would have time to find a new home. and no, this has zero to do with paramount looming as an excuse. paramount did not even make its first hostile bid for wbd until september 11 or 12. that was after tony khan was already told there would not be a wbd renewal. so what did tony khan do? tony khan turned the truth into a wrestling angle. tony khan, or one of tony khanโ€™s minions, gets dave meltzer to drop a story assigning my claims and what i have been publicly posting about tony khan to โ€œhigh level wwe officials.โ€ why? because it gives tony khan a safer enemy. tony khan does not want the story to be the actual timeline. because the actual timeline is brutal. on february 28, i said youtube was not a real media rights model unless google was actually cutting the check and underwriting production. on april 30, i said wbd passed in august, the myaew app was not realistic, paramount was not real for aew, cw / roku was off the table, amazon and fox did not want aew, and the only distributor left that made sense was google / youtube. on july 9, i said no one in hollywood believed the $185 million number. on july 10, i said aew was not leverage. on august 11, i said the major players at the top were shrinking, paramount was still interested in wbd, and google / youtube was becoming a directly competitive lane. on september 16, i said a paramount / wbd merger would fold cbs, cnn, hbo, and warner bros. ip into ellisonโ€™s orbit. on september 27, i said enjoy the show on youtube after ellison buys wbd. on september 28, i said if paramount acquires wbd, tko would push to lock down a monopoly on combat sports. on december 6, i said paramount skydance was preparing a bid for wbd long before most people admitted the obvious. on february 19, i said paramount was always my bet to acquire warner bros. and on february 28, i said it in all caps: paramount is coming for wbd. aew will lose a tv deal. that is the part tony khan cannot answer directly, because the direct answer means admitting this was never โ€œwwe is scared of us.โ€ it was always the board closing. tony khan wants the story to be: why would wwe say this about us? that is the laundering operation. take my public analysis. run it through dave meltzer. assign it to wwe / tko. then let tony khan answer a canned question on a media call with very little distribution about potentially having very little distribution. a media call for a show with very little distribution answering a canned question about aew potentially having very little distribution. based on a planted story, from a planted messenger, with a rehearsed answer, after an roh show maybe 8-15k people watched. a pr flack probably wrote it. tony khan performs hurt. tony khan says โ€œi donโ€™t know why wwe wouldโ€ฆโ€ tony khan denies the obvious. tony khan keeps me minimized. tony khan removes me from the public conversation about the very thing i have repeatedly said is going to happen to aew. everyone is supposed to pretend this is organic. it is the most bubble wrapped, manufactured, artificial environment possible. a canned and rehearsed answer at an roh media scrum about a planted dave meltzer story based on my very real and very public analysis of the media rights board. but make no mistake. tony khan was responding to my words. tony khan just laundered them through dave meltzer and assigned them to wwe / tko so tony khan could keep lying about it publicly without ever saying my name. and now, voila. dave meltzer is posting about youtube viewers and prelims. Dave Meltzer โ€” May 16, 2026 โ€œAt this moment there are 340,000 people watching prelims for Netflix on YouTube. Itโ€™s a good number.โ€ yes, dave meltzer. youtube can have good numbers. nobody said youtube cannot have good numbers. that was never the issue. the issue is whether youtube is being used as a funnel into a premium rights ecosystem or as a substitute because the premium rights ecosystem rejected you. that is the difference. that has always been the difference. netflix using youtube prelims as audience acquisition is not the same thing as aew trying to spin youtube as a media rights home because the real buyers are gone. ufc using youtube as a funnel is not the same thing as aew using youtube as a life raft. wwe sending stars to aaa on youtube to convert a younger demo is not the same thing as aew retreating to youtube after the traditional buyer board closes. and the fact that dave meltzer is now suddenly tweeting like the mayor of youtube is the punchline. because the same people who mocked the youtube outcome are now going to spend the next several months explaining why youtube is actually good. of course it can be good. for the right use case. for the right property. inside the right architecture. with the right check attached. but when you spend two years telling everyone you were valued like raw and your next stop is โ€œplease subscribe and smash that bell,โ€ maybe stop pretending this is victory formation? i told yโ€™all where this was going. the record is right there. iโ€™m still right. and tony and dave: you guys are see through translucent. thatโ€™s it for ye ๐ŸŽค๐ŸŽค๐ŸŽค

Nick LoPiccolo

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๐Ÿ”Š CHURCH: The Feast of Trumpets begins TOMORROW, FRIDAY 9/11โ€“SUNDAY 9/13โ€”and LOOK at the convergence surrounding it this year! Israel at the center. The nations focused on dividing the land. Iran and its bow bending, ready to break! War expanding. Earthquakes. Intense volcanic activity. Signs in the heavens. And all of it converging as the appointed time of the TRUMPET arrives this year on a Sabbathโ€”A DAY OF REST! ALL THE SIGNS ARE NOT QUIETING DOWNโ€”THEY ARE INTENSIFYING! KEEP LOOKING UP!!! ๐ŸŽบQUICKLY FIRST โ€” WHAT IS THE FEAST OF TRUMPETS? The Feast of Trumpetsโ€”Yom Teruahin the Bibleโ€”is one of the LORD's seven appointed feasts. It begins on 1 Tishrei, the first day of the seventh month, and God commanded it to be a day of rest, holy assembly, and trumpet blasts: ๐Ÿ“–โ€œIn the seventh month, on the first day of the month, you shall have a sabbath-rest, a memorial of blowing of trumpets, a holy convocation.โ€ Lev 23:24 ๐Ÿ‘‰๐ŸผThe trumpet was used in Scripture to call God's people together, announce movement of the camps, sound an alarm, and proclaim important occasions. And this year is extra special! ๐ŸŽบTrumpets begins this Friday at sunset September 11, 2026, and 1 Tishrei falls on a Sabbathโ€”God's day of REST. That isn't extremely rare, but the fact that the appointed time of the trumpet falls on the day of rest immediately makes me think of this verse, Isaiah 26:20: But look at what comes BEFORE: ๐Ÿ“– โ€œYour dead shall live... Awake and sing, you who dwell in dust... And the earth shall cast out the dead.โ€ Is 26:19 Then AFTER: ๐Ÿ“– โ€œCome, my people, enter your chambers, and shut your doors behind you; hide yourself, as it were, for a little moment, until the indignation is past.โ€ Is 26:20 And the next verse tells us why: ๐Ÿ“– โ€œFor behold, the LORD comes out of His place to punish the inhabitants of the earth for their iniquity...โ€ Is 26:21 ๐Ÿ”—So, look at the prophetic sequence here: FIRST, resurrection. THEN, โ€œCome, My peopleโ€โ€”enter the chambers, hide, and rest. And AFTER that comes the indignation upon the earth. THIS MAKES US THINK ABOUT PAUL: ๐Ÿ“– โ€œFor the Lord Himself will descend from heaven with a shout, with the voice of an archangel, and with the trumpet of God. And the dead in Christ will rise first. Then we who are alive and remain shall be caught up together with them in the clouds to meet the Lord in the air.โ€ 1 Thes 4:16โ€“17 Remember originally there were no chapter breaksโ€”so after saying this Paul points directly to the Day of the Lord: ๐Ÿ“– โ€œBut concerning the times and the seasons, brethren... you yourselves know perfectly that the Day of the LORD so comes as a thief in the night.โ€ 1 Thes 5:1โ€“2 Look at Paul's train of thought: ๐Ÿ‘‰๐ŸผTrumpet of God ๐Ÿ‘‰๐Ÿผ Dead in Christ rise ๐Ÿ‘‰๐ŸผChurch caught up ๐Ÿ‘‰๐ŸผThen Paul immediately turns to the Day of the LORD And centuries before Paul, look again at Isaiah's picture: ๐Ÿ‘‰๐ŸผThe dead arise ๐Ÿ‘‰๐Ÿผโ€œCome, My peopleโ€ ๐Ÿ‘‰๐ŸผEnter your chambers ๐Ÿ‘‰๐Ÿผ Hide until the indignation passes ๐Ÿ‘‰๐Ÿผ The LORD comes to punish the inhabitants of the earth THE PARALLEL IS AMAZING! And this yearโ€”coincidentallyโ€” 1 Tishrei, the first full day of Trumpetsโ€”falls on the Sabbath, which is THE DAY OF REST!! I LOVE IT!! NOW โ€” LOOK AT THE WORLD INTO WHICH THIS FEAST IS ARRIVING. This is where things get really interesting!! Because Trumpets 2026 is not arriving in a quiet world by any stretch of the imagination. It is arriving while the convergence we have already been watching seems to be getting LOUDER! ๐Ÿ—“๏ธI posted last week about Joel already, so I'm gonna try to not repeat my self. But remember what Peter said in his inaugural message to the Church at Pentecost, when he pointed directly back to Joel: ๐Ÿ“– โ€œAnd I will show wonders in heaven above and signs in the earth beneath: blood and fire and vapor of smoke. The sun shall be turned into darkness, and the moon into blood, BEFORE the coming of the great and awesome day of the LORD.โ€ Acts 2:19โ€“20 ๐Ÿ””A QUICK NOTE HERE: Some understand the Day of the LORD as referring only to Armageddon at the end of the Tribulation. I understand it as the 7 year tribulation period of judgment associated with Danielโ€™s 70th Weekโ€”not only its final battle. ๐Ÿ‘‰๐ŸผPaul says the Day of the LORD comes โ€œas a thief in the night,โ€ when people are saying โ€œPeace and safety!โ€ and then โ€œsudden destructionโ€ comes upon them (1 Thes 5:2โ€“3). After seven years of catastrophic judgment, nobody will be saying "peace and safety" as preparing for Armageddon. Back to what I was saying: since I wrote that post last week, the signs havenโ€™t gotten quieterโ€ฆ THEY JUST KEEP PILING ON!!! โš ๏ธWeโ€™re not looking at one volcano and saying, โ€œTHIS IS JOEL.โ€ Weโ€™re not looking at one earthquake, one war, one eclipse, or one column of smoke and saying, โ€œPROPHECY FULFILLED.โ€ WEโ€™RE JUST LOOKING AT THE CLUSTER. WE ARE LOOKING AT THE CONVERGENCE AND THE PROPHETIC RESEMBLANCE! And look at what has been added to that picture just as we approach Trumpets: ๐ŸŒ‹ ANAK KRAKATAU โ€” INDONESIA A continuous eruptive episode lasting approximately 25 hours. Ash sent 50,000 feet into the atmosphere. Jakarta's international airport was forced to close. Nearly 3,000 flights disrupted. 341,000 passengers stranded. When I saw those towering plumes rising, I immediately thought of Joelโ€™s language: โ€œPillars of smoke.โ€ Fire. Ash. Towering plumesโ€”so massive they were captured from space in NASA satellite imagery. ๐Ÿ”ฅ AND LOOK AT WHAT IS HAPPENING IN INDONESIA AT THE SAME TIME. From September 1โ€“7 alone, Indonesia's wildfire emissions reached 19.7 MILLION metric tons of COโ‚‚โ€”more than ONE-THIRD of the entire world's wildfire emissions during that period and 273% ABOVE the seasonal average. Authorities are calling this Indonesia's most intense wildfire season in 11 years, with massive haze now affecting millions of people. THE MIDDLE EAST IS NOT CALMING DOWN EITHER: ISRAEL โ€” IRAN โ€” AND NOW THE CONFLICT IS WIDENING: Last Thursday Prime Minister Netanyahu said: ๐ŸŽ™๏ธโ€œThe achievements are immense, but there is still more to complete. I mean, first and foremost, the toppling of the regime. This regime in Iran โ€” its end is near. It is weak, it is fighting for its life, it is faltering.โ€ ๐Ÿ””Remember what we're watching and waiting for. We're watching for that Jeremiah 49 โ€œbow of Elamโ€ to be broken, potentially opening a window of peace and security for Israel that could set the stage for Ezekiel 38. And as of September 10, the conflict is spreading even further. Iran reports attacks on ships near the Strait of Hormuz, while Houthi advances and attacks are putting the chokepoint Bab el-Mandeb at risk. Think about the geography: โš ๏ธ STRAIT OF HORMUZ โ€” The worldโ€™s #1 oil chokepoint: DISRUPTED โš ๏ธ BAB EL-MANDEB โ€” A critical global shipping chokepoint: AT RISK โš ๏ธ IRAN โ€” ISRAEL โ€” U.S. โ€” HOUTHIS โ€” SAUDI ARABIA THE WAR IS NOT CONTRACTING, IT IS WIDENING! AND THERE IS SOMETHING EVEN BIGGER HAPPENING AROUND ISRAEL RIGHT NOW. ๐Ÿ—ก๏ธAs we approach Trumpets, two days ago, Sep 8th. international pressure for a TWO-STATE SOLUTION is intensifying again. The UK, France and Canada have announced new measures to protect that outcomeโ€”and they plan to take that effort directly to the UNITED NATIONS GENERAL ASSEMBLY later this month. And THAT immediately brings us back to Joel once again. Because Joel doesn't only speak about blood, fire, pillars of smoke and signs in the heavens. He also tells us what happens when the NATIONS gather concerning ISRAEL: ๐Ÿ“– โ€œI will also gather all nationsโ€ฆ on account of My people, My heritage Israelโ€ฆ THEY HAVE ALSO DIVIDED UP MY LAND.โ€ Joel 3:2 ๐Ÿ‘‰๐ŸผTHAT is the part of the convergence I don't want us to miss. Israel is not somewhere on the sidelines of this pictureโ€”ISRAEL IS AT THE CENTER. What makes this Trumpets season so extraordinary is THESE PARTICULAR PIECES coming together clearly at the same time. And THEN, on top of that geopolitical picture, look at what has been happening in the earth and the heavens. LET'S ZOOM OUT FOR A SECOND HERE. In just the last four weeks we have watched: ๐ŸŒŽ Major earthquakes โ€” Colombia, Indonesia and Peru โšซAugust 12 โ€” Total solar eclipse ๐Ÿ”ดAugust 27โ€“28 โ€” Deep partial lunar eclipse ๐Ÿ”ฅ September 1โ€“7 โ€” Indonesia wildfire emissions running 273% above the seasonal average ๐ŸŒ‹ September 4โ€“6 โ€” Anak Krakatauโ€™s extraordinary 25-hour eruptive episode ๐Ÿ‡ฎ๐Ÿ‡ฑ September 8th: Growing international pressure for a TWO-STATE SOLUTION involving Israelโ€™s land โš”๏ธ September 10th: Israel-Iran conflict continuing to widen across the region THIS IS THE VERY TIGHT CLUSTER WEโ€™RE LOOKING AT!! And now, right as we arrive at TRUMPETS, listen to what Joel says: ๐Ÿ“–โ€œBlow the trumpet in Zion, and sound an alarm in My holy mountain! Let all the inhabitants of the land tremble; for the day of the LORD is coming, for it is at hand.โ€ Joel 2:1 ๐Ÿ“œTHE SAME PROPHET who spoke of blood, fire, pillars of smoke, the darkened sun and the blood moon ALSO CRIES: BLOW THE TRUMPET AND SOUND THE ALARM!! ๐Ÿ‘‰๐Ÿผ Againโ€”earthquakes happen, volcanoes erupt, fires burn, wars happenโ€ฆ ONE EVENT IS NOT OUR POINTโ€”THE CONVERGENCE IS! We are not declaring Joel fulfilled. We are WATCHING, just as Scripture tells us to watch. We are watching the birth pains Jesus described while also seeing striking echoes of Joelโ€™s prophetic languageโ€”and THAT is INCREDIBLY fascinating and worth paying attention to!!! ๐Ÿ”ŠChurch: The Feast of Trumpets is here! Trumpets CALLED THE ASSEMBLY. Trumpets SIGNALED THE CAMP TO MOVE. Trumpets SOUNDED THE ALARM. And now the appointed time of the TRUMPET has arrived while the convergence we have been watching is not getting quieterโ€ฆ IT IS GETTING LOUDER! Earthquakes. Fire. Bloodshed. Pillars of smoke. Signs in the heavens. THE PRESSURE OF NATIONS WANTING TO DIVIDE ISRAEL. And the โ€œbow of Elamโ€ looking closer than ever to breaking! Scripture never told us to sleep through the signsโ€”it told us to WATCH!!! So letโ€™s KEEP WATCHING, KEEP PRAYING, KEEP PREACHING THE GOSPEL!! SOON WE WILL HEAR THE TRUMPET OF GOD, ENTER OUR CHAMBERS, AND FINALLY ENTER OUR DAY OF REST!! KEEP LOOKING UP!! Maranatha! ๐Ÿค Come, Lord Jesus, COME!!!

Maranatha777

62,051 Aufrufe โ€ข vor 28 Tagen

People have been asking how I'm generating my product videos. Here's a prompt my agent wrote so you can copy its process: # Prompt: make product videos with code and AI agents Copy everything below the line into a coding agent (Claude Code, Codex, etc.). Fill in the `{{โ€ฆ}}` placeholders first. It describes how Inbox Zero produced its landing-page hero, launch films and about 15 docs and app walkthroughs, each costing well under $1 in API calls. --- You are producing product videos for **{{PRODUCT}}** ({{ONE-LINE DESCRIPTION}}). The videos are a landing-page hero (~55s), short launch films (25โ€“40s) and feature walkthroughs (45โ€“110s) for the app and docs. They are made entirely with code: there's no screen recording and no video editor. Quality matters far more than cost. The product's source code is at `{{APP_REPO_PATH}}` and its docs are at `{{DOCS_PATH}}`. The founder or reviewer is {{REVIEWER}}. They give taste feedback, and you turn that feedback into written rules. ## 1. Core idea Every video is an **HTML/CSS/JS page whose every frame is a pure function of time `t`**. Headless Chrome screenshots each frame, and ffmpeg encodes them. This gives you: - Exact, repeatable renders: a copy change means a cheap re-render, not a re-edit. - Parallel rendering, because nothing carries over from one frame to the next. - Real product UI, because the "footage" is real DOM captured from the running app. Don't use Remotion or any other video framework; a ~200-line engine is enough. Don't screen-record: recordings can't be re-timed, re-worded or kept pixel-perfect. ## 2. Set up a private video repo Create a **private** repo (e.g. `{{ORG}}/demo-video`) separate from the product repo. Its layout: ``` AGENTS.md # read-first notes for every agent: pipeline, taste rules, mistakes made README.md # catalog: every video, its branch, length, status, where it's used BRIEF.md # product truths, fictional cast, kit API, end-card and taste rules EXPLAINER.md # brief for the walkthrough format LAUNCH.md # brief for launch films MUX.md # hosting IDs for every published video engine.js # renderAt(t), addScene, spring/easing helpers, word-by-word captions render.mjs # parallel Playwright frame renderer โ†’ ffmpeg # voice + music mix with ducking and loudness normalisation judge.mjs # audio judge (picks the best TTS take) vjudge.mjs # video judge (reviews a whole render) # contact sheet from sampled frames kit/app/ # REAL app screens captured as DOM snapshots (see ยง3) kit/explainer.js # overlays: step captions, callouts, highlights, camera, cursor, typing, toasts, # and mocks of third-party UIs (Gmail, Outlook, Slack, โ€ฆ) kit/endcard.js # shared end card music/ # shared music bed(s) tools/ # upload scripts (hosting), helpers ``` **One branch and one git worktree per video** (`git worktree add -b explainer-foo ../demo-explainer-foo main`). `main` holds only shared things: the kit, the briefs and the tools. Merge `main` into a video branch to pick up kit fixes. Put kit fixes found while making a video in a separate commit so they can be cherry-picked to `main`. Commit each video's web encode, poster, `.vtt` captions and a `VARIANT.md`. That file holds the script, the timings, chapter markers, the claim checks, and any docs-vs-UI discrepancies found. Git-ignore masters and intermediate files. Keep `AGENTS.md` alive. Every time the reviewer gives feedback, or an agent makes a mistake, add a one-line rule there. This file is what makes the tenth video good on the first try. ## 3. Capture the real UI kit 1. Run the app locally with a **seeded database of fictional data**: one consistent cast (a main user plus 4โ€“5 contacts and a fictional company), and realistic but fake emails, events and numbers. Use local emulators for third-party APIs where possible. 2. Write a capture script (Playwright) that visits each screen and state the videos need. It saves the **rendered DOM plus inlined CSS** as a standalone HTML snapshot, plus a PNG for reference. Inbox Zero ended up with ~140 states. 3. Missing states can be **derived** from the nearest snapshot by editing the DOM to match the real component's source (text, classes), never invented. 4. **Audit every snapshot for leaks** before committing: real names, emails, avatars, API keys, and the capture machine's **timezone and locale**. A real city name once leaked through a timezone picker. 5. Document the states, selectors and how to recapture in `kit/app/README.md`. ## 4. Write the script (accuracy first) - Read the docs page and **the app source** for the feature. Every label, button and step on screen must match the product. Where the docs and the UI disagree, the UI wins; log the discrepancy in `VARIANT.md` and fix the docs afterwards. (This produced a steady stream of real docs fixes and bug reports.) - Check claims in code, not just in the docs. For example, does feature X actually use data Y? - Keep a list of **product truths** in `BRIEF.md`: supported platforms ("always say Gmail *and* Outlook"), trial terms, and what is early-access. - A walkthrough has a 1โ€“2s product payoff up front, then numbered steps (one caption each), one result shot, and a minimal end card. - **Intro messaging** (hero and launch) must say what the product *is* in the first line. Write several candidate openers and let the reviewer pick. ## 5. Build the timeline - `engine.js`: scenes are DOM subtrees shown and hidden with `display:none` (not `visibility`, because visible children leak through a hidden parent). All motion is computed from `t` with springs and easing. - **Render purity is mandatory**: no ` no randomness without a seed, no state carried between frames. Workers start mid-timeline. - Camera moves are CSS transforms on the snapshot, and so are cursor paths, typing and highlights. - Preview live with `npx serve .`, using `?t=17` to start at 17s. ### Taste rules (start with these; add your reviewer's) - **Openers:** light and product-native. No dark gradients, glossy fake app icons with red badges, or captions over blurred clutter. Reach the product payoff within ~2s. - **No recaps:** never repeat earlier points in words or as a montage at the end. - **End cards:** neat and centred, with a logo lockup, one line and a quiet URL. Landing cuts can carry one CTA (e.g. "Try free for 7 days") plus small platform marks. Never "ยท"-joined copy, and never a button stuffed with text. - **Legibility:** body text โ‰ฅ 20px at 1080p, no wide shot of unreadable UI for more than ~1s, no words sliced at frame edges, and captions fully settled โ‰ฅ 0.4s before the click they describe. - **Transitions:** no long crossfades between two busy UIs (the double exposure looks muddy). Use a cut, a camera push or a short blur-through. ## 6. Audio - **Voiceover:** a strong TTS model with style instructions (Inbox Zero used Gemini Flash TTS through OpenRouter). Pick one voice per format. Generate **2โ€“3 takes per line** and pick the best with an audio-capable model (`judge.mjs`): it scores pacing, mispronunciations, odd stresses and clipped endings. - **Music:** generate one shared bed per format (Inbox Zero used Lyria). Models ignore the requested length, so detect the beat grid (librosa) and cut or loop at phrase boundaries. - **Mix (` duck the music under the voice with a sidechain, then do two loudnorm passes to โˆ’14 LUFS and โˆ’1.2 dBTP. - Agents can't listen. Flag music endings and loop points for a human ear-check. ## 7. Render - `render.mjs` splits frames across N Playwright workers. Each one loads the page, sets `t` and screenshots. ffmpeg then encodes a high-quality master (CRF ~12) and a web copy (CRF ~20). - Add a screenshot timeout and retry (e.g. 120s, 5 tries); long renders hit flaky frames. - Support env vars to render a sub-range or a single segment, so fixes don't need a full render. - **On a shared machine:** cap workers (e.g. 3 per agent) and only stop your own processes by PID. Never `pkill -f render.mjs`: it kills other agents' jobs. ## 8. Review before showing anyone - Sample frames into 2ร—2 contact sheets and **look at them yourself**, zooming in on captions, edges and data. This is the main review. - Use a video-capable model (`vjudge.mjs`, Gemini Flash) for whole-video checks like timing and caption order, but **treat its output as hints**. Video and audio judges hallucinate problems, so verify every claim against frames. - Check: claims match the code, the fictional cast only, no leaks, the legibility rules, the end card. - Show the reviewer the finished mp4s (open the folder for them) along with the `VARIANT.md` discrepancy list. ## 9. Work in parallel with subagents - Once the kit and briefs exist, give **one subagent per video**. Each gets its own worktree and branch, the brief, the relevant docs page, and the instruction to read `AGENTS.md` first. - Each subagent writes the script, builds, renders, reviews and reports back with the mp4 path and the discrepancies found. - The coordinator merges kit fixes into `main`, uploads, and integrates the videos into the app and docs. ## 10. Publish - **Hosting:** use Mux (or similar) rather than YouTube embeds. You get a clean player, no recommendations and auto-subtitles. The upload script sets a public playback policy and generated English captions, and records each ID in `MUX.md`. Pass API tokens via env vars and never commit them. - **In the app:** a feature-page video button or dismissible card. **Lazy-load the player** (`next/dynamic`, `ssr:false`) so it only loads when the dialog opens and adds nothing to the page bundle. - **Docs:** a lazy ` ` at 16:9. - **Landing hero:** track `video clicked / started / progress / completed / closed` with a `video_id`. Don't A/B test the hero video: only the ~10% who click can be affected, so overall-sign-up tests are underpowered. Ship the better cut and compare cuts on watch-through and viewer โ†’ sign-up by `video_id`. - **YouTube:** the API locks uploads from unaudited projects to private, so upload in Studio and schedule one video every ~2 days. If an agent automates Studio, set text with `execCommand('insertText')`, type dates with real keystrokes, and **read every value back before clicking Schedule**. - If the product repo is public, keep commit and PR text free of private details. If it mounts private submodules, grep them before removing any shared component. ## 11. Mistakes we already made (don't repeat them) - Invented UI in v1, where the reviewer's first note was "show real UI". โ†’ Real DOM snapshots only. - Claims the product doesn't make (e.g. "important emails move to the top" when they're actually labelled). โ†’ Check in code. - Taglines the company doesn't use. โ†’ Offer options and let the reviewer pick, then record the pick. - A real timezone leaked in a snapshot and was committed to history. โ†’ Audit before committing. - Agents killed each other's renders with `pkill`. โ†’ Stop processes only by your own PID. - A judge model "found" skips and glitches that weren't there. โ†’ Verify against frames. - Removing a shared component broke production through a private submodule. โ†’ Grep it first. - A free hosting plan capped the asset count, and the upload script swallowed the error. โ†’ Scripts must surface API errors. ## Deliverables per video - [ ] `out/ -web.mp4`, poster, `.vtt`, and chapter markers - [ ] `VARIANT.md`: script, timings, claim checks, docs/UI discrepancies - [ ] An entry in the `README.md` catalog, and its hosting ID in `MUX.md` - [ ] Any new rules learned are added to `AGENTS.md`

Elie Steinbock

19,696 Aufrufe โ€ข vor 3 Tagen

๐Ÿšจ๐Ÿ‡บ๐Ÿ‡ฆ INTERVIEW: THE FALL OF POKROVSK - UKRAINEโ€™S BIGGEST LOSS OF THE WAR Ukraineโ€™s strongest fortress in the east is about to fall In the meantime, Ukraine is running out of Patriot missiles, struggling to get Tomahawks, while Russia continues to incrementally gain territory Will Trump and the EU turn things around? Denys Davydov, one of Ukraineโ€™s most trusted military voices, doesnโ€™t think soโ€ฆ We discuss: โ€ขโ  โ How Russian glide bombs and drone swarms wiped out entire brigades โ€ขโ  โ Why Ukraineโ€™s Patriot systems are nearly empty and running on scraps โ€ขโ  โ How U.S. Tomahawks can help but wonโ€™t turn the tide โ€ขโ  โ And what happens next if the West doesnโ€™t escalate support immediately Captain Deny warns the fall of Pokrovsk is a turning point, and the next few months will decide whether Ukraine stands or falls. 01:10 โ€“ Why glide bombs are changing the battlefield 01:32 โ€“ Pokrovskโ€™s fall could make Donbas indefensible 02:10 โ€“ Why Russia wants Ukraine as a pro-Russian puppet state 03:00 โ€“ The fight for Pokrovsk and whatโ€™s at stake 04:15 โ€“ 80% of Pokrovsk now infiltrated by Russian infantry 06:20 โ€“ Why Ukrainian evacuation came too late 07:35 โ€“ Special forces landed, but impact minimal 08:05 โ€“ Pokrovskโ€™s fall would cripple Ukraineโ€™s economy and supply lines 09:30 โ€“ Ukraine counterattacking in the north, holding back collapse 10:15 โ€“ Why Putin wonโ€™t accept any U.S.-brokered peace deal 11:22 โ€“ Trumpโ€™s proposal for Ukraine to give up Donbas and freeze the war 12:25 โ€“ Why Ukraine refuses to surrender territory 13:10 โ€“ Could European peacekeepers change the equation 14:25 โ€“ The front line is too vast to control 15:10 โ€“ Ukraineโ€™s limited resources and fading options 16:15 โ€“ Why Davydov says Ukraine canโ€™t retake Crimea or Donbas 17:20 โ€“ โ€œOnly a Russian collapse can end this warโ€ 18:05 โ€“ Casualties rising on both sides 19:00 โ€“ Ukraine now conscripting civilians from the streets 19:45 โ€“ Russiaโ€™s manpower advantage 8-to-1 20:05 โ€“ How Ukraine still holds despite being outnumbered 21:40 โ€“ Ukraine fighting to preserve identity, not just land 22:40 โ€“ Why surrender would erase Ukrainian culture 23:05 โ€“ Can Tomahawks or new U.S. weapons change the war 23:50 โ€“ Davydov says Tomahawks are โ€œmostly political theaterโ€ 24:45 โ€“ Sanctions hurt but are short-lived without enforcement 25:25 โ€“ Flamingo vs Neptune: Ukraineโ€™s missile problem 27:00 โ€“ Why Russia has no incentive to freeze the lines 28:10 โ€“ Keeping 800,000 soldiers busy keeps Putinโ€™s regime stable 29:10 โ€“ War fatigue in Russia isnโ€™t enough to stop the Kremlin 30:05 โ€“ Russiaโ€™s economy built to survive sanctions 31:35 โ€“ China and Turkey keeping Russiaโ€™s trade alive 33:05 โ€“ Trumpโ€™s new sanctions on Rosneft and Lukoil 34:10 โ€“ Davydov warns sanctions will be bypassed within months 34:55 โ€“ โ€œCheap oil is financially addictiveโ€ 35:40 โ€“ What Ukraine needs now: guarantees, not promises 36:25 โ€“ The limits of Western aid and the illusion of support 37:45 โ€“ Why Europe still buys Russian energy 38:30 โ€“ Davydov says Ukraineโ€™s only hope is time and attrition 39:55 โ€“ The Black Swan scenario: another Prigozhin moment 40:40 โ€“ Why Putin fears his soldiers returning home more than NATO 42:15 โ€“ Western societies value life, Russia values endurance 43:30 โ€“ The roots of the war: invasion, NATO, and broken promises 45:15 โ€“ Crimea was seized while Ukraine was neutral 47:00 โ€“ Why Davydov says NATO is weaker than people think 48:30 โ€“ NATOโ€™s hesitation vs. Russiaโ€™s aggression 49:55 โ€“ โ€œPutin used NATO as an excuse to attackโ€ 50:35 โ€“ Russiaโ€™s justification: โ€œprotecting Donbasโ€ 52:20 โ€“ Why Ukraine can never be neutral 53:05 โ€“ The Monroe Doctrine argument and U.S. hypocrisy 54:00 โ€“ Denys: NATO threat to Russia was zero 55:00 โ€“ Why Russiaโ€™s war is ideological, not defensive 56:45 โ€“ China says it will never let Russia lose 57:50 โ€“ Beijingโ€™s fear of a U.S. victory 58:20 โ€“ Trumpโ€™s opportunity: make China and Russia compete 59:30 โ€“ The U.S. still holding back military power 01:00:25 โ€“ Europe funding both sides of the war 01:01:20 โ€“ How fast Ukraine can train F-16 and A-10 pilots 01:02:00 โ€“ Why Ukraine needs 300 fighter jets to win air superiority 01:03:00 โ€“ Patriot systems nearly depleted 01:04:45 โ€“ โ€œWithout air defense, every village can be erasedโ€ 01:06:20 โ€“ Closing thoughts: no peace without pressure, no survival without support

Mario Nawfal

1,828,232 Aufrufe โ€ข vor 11 Monaten

*** Test Your 9/11 Knowledge: The Explosive Evidence at the 3 WTC Towers The 50 Questions NIST Should Have Asked 20 Years Ago! WTC Building 7 Free-fall 1. How is it possible that 47-story Building 7 fell suddenly, symmetrically in free-fall acceleration, without any resistance from any of its 81 columns? 2. Why did NIST deny its free-fall for 7 years, only to be proven wrong and be forced to officially admit that it did collapse in free-fall? Symmetry 3. How, if Building 7 was damaged asymmetrically in the north-east corner on floor twelve, as per the NIST report, could it fall symmetrically downward? Shouldnโ€™t the building have tilted toward its damaged side โ€“ and not fall straight down through the path of what was the greatest resistance? Fires 4. How could a few, small, and scattered ordinary office fires have brought this Type-1 fire-protected steel-frame skyscraper down, when several dozen examples of much hotter, much larger, and longer-lasting fires have never in history brought down such a building? 5. How could normal office fires take out all the columns in the building sequentially floor by floor, in 7 seconds? 6. Why did NIST claim that the fires were still burning, up until the time of the collapse, when the photos show that they were burnt out more than an hour before the collapse? 7. Why arenโ€™t all the firefighters concerned, in the wake of the NIST report during the last 24 years, that such ordinary fightable fires can now bring skyscrapers down on top of them, and on top of the public who are told to โ€œdefend in placeโ€ in the building (and not obstruct access by firefighters)? 8. Why are many of these same firefighters calling for a new investigation of the NIST report itself? Controlled Demolition 9. Since the collapse of Building 7 looks exactly like a controlled demolition, why did NIST avoid any serious consideration of this hypothesis? 10. How could a 40,000-ton moment-resisting and X-braced structural steel frame collapse like a house of cards in 7 seconds, with most of its columns and beams severed โ€“ one from another? 11. Why does WTC 7 have all of the key features of typical controlled demolition, and none of the features of collapse by fire? Explosions 12. Why didnโ€™t NIST include in its report on WTC 7 the half-dozen witnesses of explosions prior to its collapse, and even claim that there were no witnesses? 13. What could have caused an elevator cab to be โ€œblown 30 feet out of its hoistway,โ€ as Deputy Director of NY-Office of Emergency Management, Richard Rotanz, reported at Noon, when the building didnโ€™t collapse for another 5 hours. 14. What caused Barry Jennings and Michael Hess to be injured by explosions and subsequently trapped in the building before either Twin Tower collapsed? Foreknowledge 15. Why did Fire Chief Nick Visconti declare, โ€œWeโ€™re moving the command post over this way, that buildingโ€™s coming down!โ€? 16. How could Fire Chief Haydenโ€™s engineer declare, upon being asked, โ€œhow long until the building comes down?โ€ โ€“ then accurately state, โ€œIn its current state you have about 5 hours,โ€ when no steel-frame fire-protected high-rise had ever come down due to fire alone? 17. Why did construction workers, while walking away from Building 7 and upon hearing an explosion from the building, look straight into the CNN camera saying, โ€œYou hear that? Keep your eye on that building. That thingโ€™s coming down. The building is about to blow up, flame and debris coming downโ€? 18. Why did former Air Force medic Kevin McPadden hear a โ€œ3-2-1โ€ countdown on the radio, and subsequently hear explosions before Building 7 collapsed? 19. How could the BBC have announced, live on TV, the collapse of WTC 7 20 minutes before it collapsed? 20. Why did CNN announce, 7 hours early, the 10:45 AM collapse of a 50-story building (obviously referring to Building 7)? Expert Statements 21. Why have more than 3,600 Architects & Engineers signed onto the petition at demanding a new 9/11 WTC investigation? 22. Why are dozens of structural engineers making statements such as: โ€œA localized failure in a steel-framed building like WTC 7 cannot cause a catastrophic collapse like a house of cards, without a simultaneous and patterned loss of several of its columns at key locations within the buildingโ€? 23. Why did the top European controlled demolition expert declare: โ€œThat is controlled demolition. Itโ€™s been imploded. Itโ€™s a hired job. A team of experts did this? 24. Why did top forensic structural engineer, Prof. Leroy Hulsey from the University of Alaska, following a 4-year study of WTC 7, declare: โ€œThe collapse of WTC 7 was a global failure involving the near-simultaneous failure of all columns in the building and not a progressive collapse, as claimed by NIST. Extreme Heat Molten Metal 25. What does it mean that FEMA, in its 2002 Report, including a metallurgical examination of the WTC 7 steel, revealed โ€œa phenomenon never before observed in building firesโ€ฆ.a liquid eutectic mixture containing primarily iron, oxygen, and sulfur formed during this hot corrosion attack on the steel...โ€ Why did NIST eliminate this metallurgical report from their final report? 26. Did Fire Protection Engineer Jonathan Barnett know, when he said, โ€œsteel members in the debris pile that appear to have been partly evaporated,โ€ that it takes 4,000ยฐF to evaporate steel? And that jet fuel and office fires donโ€™t even rise to a third of that temperature? 27. Why is there bright yellow molten steel or iron pouring out of the crab claw excavators in the WTC pit? And out of the South Tower just minutes before its collapse. 28. Why did the first responders in the pit report, โ€œyou get down in the pile, and you see molten steel โ€“ flowing down the channel rails, like lava from a volcanoโ€? Did they know that it takes 3,000ยฐF to melt steel, and that office fires and jet fuel can only achieve half of this temperature? 29. What can explain the well-documented 3,000ยฐF temperatures that are well-documented in the WTC Twin Towers collapse aftermath? Why is there evidence of ignited thermite found by so many first responders in the WTC pile? Previously Molten Iron Microspheres 30. What does it mean that the US Geological Survey and RJ Lee Group independently documented billions of previously molten iron-rich microspheres in ALL of the WTC dust samples? Where would the required 3,000ยฐF come from? Could the ignited thermite have created those molten iron microspheres? 31. Why is bright yellow molten steel or iron pouring out of the South Tower just minutes prior to its collapse? 32. What explains the 2009 peer-reviewed findings from the Niels Harrit research team of dual-layered red-gray chips of nano-thermite in all the independently-collected dust samples they analyzed? Why do they ignite at the same temperature as military grade โ€œsuper-thermiteโ€? Why do they produce molten iron-rich microspheres when ignited? 33. What does it mean that Harritโ€™s international research team found that the โ€œred layer of the red/gray chips in all of their WTC dust samples is active unreacted thermitic material, incorporating nanotechnology, and is a highly energetic pyrotechnic or explosive materialโ€? The Twin Towers Official Explanation 34. How can the official explanation of the Twin Towersโ€™ collapse be true (that an intact top section drove down the rest of the building after weakening of some of the structural steel in the impact zone) when this top section had already been destroyed in the first 3 seconds of the collapse (telescoping in on itself) and so was not even available to drive anything down to the ground? NIST claims that the top part of the building drove the rest of the building down to the ground. Why then do none of the photos or videos show such a top part driving anything down? And why didnโ€™t that top โ€œpile driverโ€ drive down the 800-foot-tall group of columns standing for 6 seconds after the overall collapse? 35. Why did Zdenek Bazant, in his calculations for his controversial paper submitted to the Journal of Engineering Mechanics on 9/13/01( only two days after 9/11) use twice the actual mass of the upper section of the North Tower above the impact floors and only one third of the actual column strength of the larger building section beneath it in his support for NIST collapse theory? a. Why is this paper still today the key theoretical basis of NISTโ€™s column failure theory? 36. Why does the destruction of the towers look more like a volcanic eruption (than a straight-down gravitational collapse) with upward and outward arching streamers, a geometry of fireworks, freely flying solid molten objects trailing thick white smoke clouds? Witnesses of Explosions 37. Why are there 156 First Responder witnesses of explosions โ€“ seeing, hearing, and feeling explosions โ€“ many of them BEFORE the towers ever came down? 38. Why did NIST claim that there were โ€œno witnesses of explosionsโ€ when there were as many as 200 publicly recorded testimonies โ€“ many before the collapse? What could explain Fire Chief Frank Cruthersโ€™ testimony that, โ€œโ€ฆ an explosionโ€ฆ appeared at the very top, simultaneously from all four sides, materials shot out horizontally. And then there seemed to be a momentary delay, before you could see the beginning of the collapseโ€? 39. Why did 36 reporters on the day of 9/11 report the WTC destruction as an explosion-based event, most of them actual witnesses of explosions? a. Why did the mainstream national media change the story the next day from explosion-based collapses to โ€œfire-induced collapsesโ€? 40. Why did the FBI, NYPD, and FDNY on the day of 9/11 all state that they suspected that explosives were used to bring down the towers, but change their story in the following week to fire-induced collapse? Seismic Evidence 41. Why did the Richter Scale recordings from Lamont Doherty Earth Observatory document significant seismic events for both towers, more than a dozen seconds before the planes hit either tower โ€“ corroborating the explosive testimony of William Rodriguez and others of massive explosions in the basement prior to the plane hitting the buildings? 42. Why did the seismic evidence from Lamont Doherty Earth Observatory document significant seismic events, in the North Tower, 5 seconds before the heaviest debris from each tower struck the ground? And in the South Tower, 7 seconds before any debris struck the ground? Wouldnโ€™t this seismic evidence corroborate the testimony of the first responders that saw, heard, and/or felt explosions before the towers fell? 43. Why did at least 3 of the tripod-mounted cameras (two on the ground and one on the rooftop) โ€œshakeโ€ 3 to 10 seconds before each of the towers fell? Would the camera evidence corroborate the seismic evidence and the first responder's explosive testimony? Explosive Evidence 44. Since the damage from the planes and fires was so asymmetrical, why was the destruction itself so precisely symmetrical โ€“ all the way down each face of each tower? Why do the videos show precise rows of individual explosions progressing down the towers โ€“ floor by floor? 45. Why do we see in the videos isolated pin-point explosive ejections occurring 20, 40, and even 60 stories down below the downward-traveling zone of destruction in each tower? Descent Profile and Speed 46. Why did the top sections of each tower descend suddenly, smoothly, down with no stoppage or โ€œjoltโ€ upon impact with the cold, hard, intact steel columns below the floors of the plane impacts? 47. How was it possible that the top section of each Tower descended without slowing at all, but instead accelerated, as if 80,000 tons of steel beneath wasnโ€™t even there? What happened to the steel? Lateral Ejection of Steel 48. Why do we see in the videos the lateral ejection out of both of the Towers of hundreds of freely flying structural steel sections each weighing 4 to 8 tons, at 80mph, landing up to 600 feet in every direction, impaling all of the surrounding skyscrapers? Why are they trailing thick white smoke clouds when steel is not flammable in office fires, or under jet fuel conditions? Could this be due to the other byproduct of thermite โ€“ aluminum oxide ash? 49. Since FEMA officially documented a 1200-foot diameter zone of flying, fallen, and impaled structural steel beyond the footprints of both Towers, how could that steel, which comprised 1/3 of the weight of the falling section of each building, have still been available to crush the lower part as NIST claimed? Missing Floors 50. Since there were 110 concrete floors, each an acre in size, and since they were not stacked up in pile of โ€œpancakesโ€ at the bottom, and since a third of the WTC dust in the 3โ€ thick blanket across Lower Manhattan from river to river is powdered concrete, then how could the concrete floors (also 1/3 of the weight of each Tower) be available to crush the building below? 51. What extreme-high temperature could have reduced 90,000 tons of concrete in each Tower back to its original aggregate, sand, and cement powder? Demolition Access 52. How could the perpetrators have gained access to the Towers to plant high energy explosives and incendiaries? Could a massive fireproofing upgrade project in the months and years prior to 9/11 have provided access to the underside of the floor systems to apply sprayed-on nano-thermite? Is it a coincidence that the WTC fireproofing upgrades occurred mostly on the floors that were hit by the planes on 9/11? Could the largest elevator modernization in the world in the 9 months prior to 9/11 have provided access to the core columns and beams? Is it just a coincidence that Ace Elevator employees were pulled out of the Towers on 9/11 for โ€œunion meetingโ€? Destruction of Evidence 53. Why was 99% of the WTC structural steel crime scene evidence loaded onto barges starting just 2 weeks after 9/11 and shipped to China for recycling before structural engineers and metallurgists could get their hands on it to do a proper forensic investigation? We encougage you to ask these questions of your elected representatives and the media. We address most of these questions in our presentations and podcast and radio interviews. So get is in front of them! Who do you know that might interview RichardGage911 about the explosive destruction of the 3 World Trade Center Skyscrapers on 9/11?

Richard Gage, AIA, Architect

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