Charlotte Crowe's banner
Charlotte Crowe's profile picture

Charlotte Crowe

@CharlCrowe • 1,049 subscribers

Postdoctoral Fellow @Genentech / PhD & Postdoc @AlessioCiulli @UoDCeTPD 🏴󠁧󠁢󠁳󠁣󠁴󠁿🇬🇧/ MChem @univofstandrews / from Strasbourg 🇫🇷

Shorts

Mechanistic and structural insights into degrader-targeted protein ubiquitinability, now out in Science Advances! Let's make more degraders that hit the bull's eye 🎯 Alessio Ciulli Centre for Targeted Protein Degradation

Mechanistic and structural insights into degrader-targeted protein ubiquitinability, now out in Science Advances! Let's make more degraders that hit the bull's eye 🎯 Alessio Ciulli Centre for Targeted Protein Degradation

27,399 görüntüleme

Excited to share our structural snapshots of MZ1-targeted Brd4BD2 ubiquitination in bioRxiv! Alessio Ciulli Centre for Targeted Protein Degradation We use cryo-EM to capture states of the dynamic Brd4BD2-MZ1-(NEDD8)-CRL2VHL-UBE2R-Ub complex 🔗

Excited to share our structural snapshots of MZ1-targeted Brd4BD2 ubiquitination in bioRxiv! Alessio Ciulli Centre for Targeted Protein Degradation We use cryo-EM to capture states of the dynamic Brd4BD2-MZ1-(NEDD8)-CRL2VHL-UBE2R-Ub complex 🔗

12,773 görüntüleme