Danielle Beckman
@DaniBeckman • 39,377 subscribers
PharmD, MS in Biophysics, PhD in Biochemistry I like taking photos of weird things inside the brain 🔬 🇧🇷 Rio 🇺🇸 Sacramento 🇩🇪 Munich
Shorts
Videos
Had fun putting this video together 😎 Whole-body imaging is opening new possibilities for biology. Two new preprints from Deep Piction showcase what's possible when whole-body imaging meets molecular biology: 🔬 DISCO-seq: anatomically guided single-cell transcriptomics. 🚀 LipiGo: next-generation targeted lipid nanoparticles. Seeing the whole picture changes the questions we can ask. Happy #FluorescenceFriday!
Danielle Beckman47,623 Aufrufe • vor 2 Tagen
Imagine being a badass scientist, MIT Physics, Forbes 30u30, and having millions of followers on multiple social media communicating about sciences. Just married, full of hopes and dreams. Suddenly, this is everyday life for you. This is the reality of Dianna Cowern and so many others. It can happen to anyone. #LongCovid #NotjustaFlu
Danielle Beckman3,624,403 Aufrufe • vor 2 Jahren
Biology was never meant to be studied in 2D. One of the coolest things about my new work is being able to visualize: 🧠 Neural circuits 🩸 Vascular networks 🎯 Drug biodistribution 🎗️ Disease progression Here's a small glimpse of what we're building at Deep Piction🤩🔬
Danielle Beckman38,077 Aufrufe • vor 13 Tagen
People who tested positive for #COVID have a higher risk of being diagnosed with other infections in the following months. This has been shown for years and hundreds of publications in the topic. Covid has an impact on the immune system we still don't fully understand.
Danielle Beckman48,641 Aufrufe • vor 1 Monat
My last post about being sick with #COVID19 attracted much attention, good and bad. For those who wished me well, thank you very much! I have already recovered my sense of smell and taste and am improving from Covid symptoms every day. For the denialists who took precious time of their lives to come to my post and say that the virus does not exist or that it is just a common cold, just a message: I directly see the virus in the brain using microscopy, and you can see it as well in the video I made below. Viral protein (red, viral nucleocapsid) is found mainly inside neurons (blue, neun) in the olfactory cortex. Glial cells such as astrocytes (white, gfap) and microglia (green, iba1( are attacking these infected neurons, trying to slow down the viral spreading across the brain. Although beneficial, this mechanism also generates more neuroinflammatory propagation, with additional collateral damage to the circuits besides the death of infected neurons. You can deny as much as you want that this is happening, but science is here clearly proving what is going on. Our first study was published last year: We are currently also looking at how vaccines can modulate this type of neuronal damage. So far, it seems that, although not able to prevent neuronal infection, vaccination reduces the neuroinflammatory response generated by the immune system in the brain. More to come soon! #FluorescenceFriday
Danielle Beckman387,777 Aufrufe • vor 2 Jahren
Sarah Sarah Buckel, another person affected with severe #LongCovid, opted to end her life and applied for assisted suicide. I feel so helpless and heartbroken. Too many are suffering from a disease that most people choose not to think about. It is just the flu, they say. These stories need to be seen. Please help us spread awareness about Long Covid.
Danielle Beckman152,676 Aufrufe • vor 1 Jahr
If you have to watch one single video in your life about Myalgic Encephalomyelitis (#MECFS), please watch the one below by Jennifer Brea🦒. Since the pandemic started, the number of people suffering like this has skyrocketed. The time to inform ourselves is now. #LongCovid
Danielle Beckman159,365 Aufrufe • vor 2 Jahren
This is what Jay Bhattacharya, the new head of NIH, has to say about vaccinating kids for #COVID. This interview was conducted 3 months ago. He doesn't see a benefit because the kids are not dying, completely dismissing the millions getting impaired with #LongCovid.
Danielle Beckman92,178 Aufrufe • vor 1 Jahr
I am just a microscopist with social anxiety. But seeing #Covid impact on the brain through the lenses of the microscope has affected me. It’s hard not to feel for the millions sick everywhere. Below is a 2021 video about our research. Can we please keep talking about #LongCovid
Danielle Beckman54,763 Aufrufe • vor 1 Jahr
*The uninvited guest* (sound on) Third week of observing scary things under the microscope: watching #SARSCoV2🟣 positive cells arrive in the brain. Note it's still inside a blood vessel and being checked by astrocytes🟢and microglia🔵. What happens next? 😨 #FluorescenceFriday
Danielle Beckman24,162 Aufrufe • vor 8 Monaten
Armond has #LongCovid. This is his experience. #CountLongCovid
Danielle Beckman28,922 Aufrufe • vor 11 Monaten