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Eric Topol

@EricTopol • 791,066 subscribers

physician-scientist, author of SUPER AGERS https://t.co/ZEdooyyJpP and Ground Truths: https://t.co/YhatcBT0hA

Shorts

Boosting mitochondria number and function to slow cellular aging

Boosting mitochondria number and function to slow cellular aging

122,126 views

What does the endoplasmic reticulum look like in a live cell, thanks to super-resolution microscopy? Nature Methods

What does the endoplasmic reticulum look like in a live cell, thanks to super-resolution microscopy? Nature Methods

24,010 views

What if you could use #AI to find and accurately excise the culprit cells, quantify >5,000 proteins in each, and find a cure for a life-threatening disease that has no effective treatment? That's the beginning of spatial medicine, a momentous medical advance. In the new Ground Truths Because X auto-suppresses the link, you can find it in my profile

What if you could use #AI to find and accurately excise the culprit cells, quantify >5,000 proteins in each, and find a cure for a life-threatening disease that has no effective treatment? That's the beginning of spatial medicine, a momentous medical advance. In the new Ground Truths Because X auto-suppresses the link, you can find it in my profile

73,934 views

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AI is putting life science at full throttle. Perspective on the remarkable recent progress and concerns, by Patrick Hsu, in the new Ground Truths clip below, with transcript, open-access
1:22
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AI is putting life science at full throttle. Perspective on the remarkable recent progress and concerns, by Patrick Hsu, in the new Ground Truths clip below, with transcript, open-access

Eric Topol

43,401 views • 2 days ago

Real time video of tumor infiltrating lymphocytes attacking cancer cell
1:00
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Real time video of tumor infiltrating lymphocytes attacking cancer cell

Eric Topol

169,942 views • 6 months ago

Persistence of #SARSCoV2 spike protein (red) in the skull bone marrow and meninges, an immune reservoir niche at autopsy in people who had Covid, work by Ali Max Erturk and colleagues
0:29
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Persistence of #SARSCoV2 spike protein (red) in the skull bone marrow and meninges, an immune reservoir niche at autopsy in people who had Covid, work by Ali Max Erturk and colleagues

Eric Topol

582,584 views • 2 years ago

A holistic, dynamic, real-time view of a person's cancer, such as their immune response to the tumor, like wastewater surveillance for infectious diseases
0:48
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A holistic, dynamic, real-time view of a person's cancer, such as their immune response to the tumor, like wastewater surveillance for infectious diseases

Eric Topol

15,478 views • 18 days ago

An AI foundation whole-body 3D model that assesses perturbations (such as obesity) across multiple systems (such as immune, neural) at the cell level. This is MouseMapper. Imagine HumanMapper someday nature Ali Max Erturk
0:20
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An AI foundation whole-body 3D model that assesses perturbations (such as obesity) across multiple systems (such as immune, neural) at the cell level. This is MouseMapper. Imagine HumanMapper someday nature Ali Max Erturk

Eric Topol

44,078 views • 2 months ago

For 12 years, Joanna Stern was the The Wall Street Journal tech journalist. In 2025, she spent a year ALL IN with AI, evaluating >100 products, and wrote a book that serves as both a great AI primer and a brutally honest assessment. She's also so funny (AI called her the next Tina Fey). Here's a clip
1:21
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For 12 years, Joanna Stern was the The Wall Street Journal tech journalist. In 2025, she spent a year ALL IN with AI, evaluating >100 products, and wrote a book that serves as both a great AI primer and a brutally honest assessment. She's also so funny (AI called her the next Tina Fey). Here's a clip

Eric Topol

44,551 views • 2 months ago

What does the totality of data on menopause hormonal treatment tell us? A lightning round with Jennifer Gunter on osteoporosis, heart disease, blood clots, cognitive health, diabetes and insulin resistance, longevity. + MHT needs to be individualized.
1:57
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What does the totality of data on menopause hormonal treatment tell us? A lightning round with Jennifer Gunter on osteoporosis, heart disease, blood clots, cognitive health, diabetes and insulin resistance, longevity. + MHT needs to be individualized.

Eric Topol

101,099 views • 7 months ago

What's ruffling? Large veins interfacing the skull (venous sinuses) that patrol immune cells and help drain the brain
0:35
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What's ruffling? Large veins interfacing the skull (venous sinuses) that patrol immune cells and help drain the brain

Eric Topol

67,768 views • 5 months ago

This year 5 tech companies have introduced AI chatbots to consumers for health support Anthropic Perplexity OpenAI Microsoft Amazon nic nguyen, a The Wall Street Journal journalist, tried some out. gift link
0:35
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This year 5 tech companies have introduced AI chatbots to consumers for health support Anthropic Perplexity OpenAI Microsoft Amazon nic nguyen, a The Wall Street Journal journalist, tried some out. gift link

Eric Topol

43,840 views • 3 months ago

Visualizing RNA in live cells using CRISPR Doudna Lab Nature Biotechnology
0:23
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Visualizing RNA in live cells using CRISPR Doudna Lab Nature Biotechnology

Eric Topol

137,800 views • 1 year ago

the 4W's for prevention
1:13
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the 4W's for prevention

Eric Topol

11,838 views • 26 days ago

Research support for rare diseases, which cumulatively affect ~30 million Americans, is primarily derived from NIH. Such work is exemplified by Anna Greka Broad Institute in a new Ground Truths podcast. Open-access, w/ transcript, full video, no ads
0:55
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Research support for rare diseases, which cumulatively affect ~30 million Americans, is primarily derived from NIH. Such work is exemplified by Anna Greka Broad Institute in a new Ground Truths podcast. Open-access, w/ transcript, full video, no ads

Eric Topol

101,523 views • 1 year ago

Ian Chalmers quote: “The scandalous failure of science to cumulate evidence scientifically.” and the lack evidence about invasive childbirth (clip)
1:02
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Ian Chalmers quote: “The scandalous failure of science to cumulate evidence scientifically.” and the lack evidence about invasive childbirth (clip)

Eric Topol

15,225 views • 1 month ago

One of the most enthralling interviews I've ever done. Geoffrey Hinton, the Godfather of A.I., w/his views on use in healthcare, how LLMs understand & exhibit empathy, and concerns about safety going forward. w/ transcript + relevant external links Ground Truths link in profile
0:58
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One of the most enthralling interviews I've ever done. Geoffrey Hinton, the Godfather of A.I., w/his views on use in healthcare, how LLMs understand & exhibit empathy, and concerns about safety going forward. w/ transcript + relevant external links Ground Truths link in profile

Eric Topol

156,939 views • 2 years ago

The 1st approval for genome editing is a historic medical milestone. But it's indirect, disruptive, and rudimentary—just getting started. Hear David R. Liu give a master class on genome editing's future. With transcript, relevant external links & Figures, in Ground Truths (profile)
0:42
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The 1st approval for genome editing is a historic medical milestone. But it's indirect, disruptive, and rudimentary—just getting started. Hear David R. Liu give a master class on genome editing's future. With transcript, relevant external links & Figures, in Ground Truths (profile)

Eric Topol

111,757 views • 2 years ago

Echocardiography is one of the most complex medical image sets to analyze, with multiple views + cardiac motion. A new nature paper shows how A.I. can do that and provide accurate reports David Ouyang, MD
0:25
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Echocardiography is one of the most complex medical image sets to analyze, with multiple views + cardiac motion. A new nature paper shows how A.I. can do that and provide accurate reports David Ouyang, MD

Eric Topol

33,814 views • 8 months ago

From a wide-ranging conversation of VNS for autoimmune diseases, and the big role of the vagus nerve for health and disease
1:03
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From a wide-ranging conversation of VNS for autoimmune diseases, and the big role of the vagus nerve for health and disease

Eric Topol

24,986 views • 5 months ago

A conversation with Jennifer Gunter on many current women's health issues, including the recent change in FDA policy (brief clip below)
2:02
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A conversation with Jennifer Gunter on many current women's health issues, including the recent change in FDA policy (brief clip below)

Eric Topol

24,974 views • 7 months ago

A 360° on #LongCovid with Hannah Davis
0:26
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A 360° on #LongCovid with Hannah Davis

Eric Topol

69,893 views • 3 years ago

When critics attack
2:00
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When critics attack

Eric Topol

17,034 views • 6 months ago