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Peter Attia

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Anya Rossi

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Lifestyle factors that shape Alzheimer’s risk | Lisa Mosconi, Ph.D. (Dr. Lisa Mosconi) This clip is from episode # 381 of The Drive which was released on 1/26/26. In the full episode, we cover: -What preclinical Alzheimer’s disease looks like in women: insights from advanced brain imaging into metabolic and structural changes that precede symptoms -How Alzheimer’s compares with other dementias: differences in prevalence, underlying pathology, symptom progression, and the challenges of accurate diagnosis -Hormone therapy and brain health: what the evidence suggests about menopausal hormone therapy, the legacy of the WHI, why timing and formulation matter, and how SERMs may offer a targeted approach -Reducing risk across midlife: genetics (including APOE4), modifiable lifestyle factors, sleep, metabolism, mood, and emerging therapies such as GLP-1 agonists within a long-term brain health framework Listen (Ep. # 380) to the full episode on my website ( or your favorite podcast player.

Lifestyle factors that shape Alzheimer’s risk | Lisa Mosconi, Ph.D. (Dr. Lisa Mosconi) This clip is from episode # 381 of The Drive which was released on 1/26/26. In the full episode, we cover: -What preclinical Alzheimer’s disease looks like in women: insights from advanced brain imaging into metabolic and structural changes that precede symptoms -How Alzheimer’s compares with other dementias: differences in prevalence, underlying pathology, symptom progression, and the challenges of accurate diagnosis -Hormone therapy and brain health: what the evidence suggests about menopausal hormone therapy, the legacy of the WHI, why timing and formulation matter, and how SERMs may offer a targeted approach -Reducing risk across midlife: genetics (including APOE4), modifiable lifestyle factors, sleep, metabolism, mood, and emerging therapies such as GLP-1 agonists within a long-term brain health framework Listen (Ep. # 380) to the full episode on my website ( or your favorite podcast player.

444,817 次观看 • 9 个月前

How scheduling sex can rekindle desire | Sally Greenwald, M.D. This clip is from episode # 371 of The Drive which was released on 11/3/25. In the full episode, we cover: -The physiology of the female orgasm, sexual comfort and satisfaction, and the disparity between men and women -Foreplay, the science of desire, and methods to help women cultivate arousal and connection -Understanding sexual desire, how to cultivate it, the role of hormones, and testosterone therapy in women -Considerations for choosing contraceptives and hormonal therapies during perimenopause -More Watch or listen (Ep. # 371) to the full episode on my website ( or your favorite podcast player.

How scheduling sex can rekindle desire | Sally Greenwald, M.D. This clip is from episode # 371 of The Drive which was released on 11/3/25. In the full episode, we cover: -The physiology of the female orgasm, sexual comfort and satisfaction, and the disparity between men and women -Foreplay, the science of desire, and methods to help women cultivate arousal and connection -Understanding sexual desire, how to cultivate it, the role of hormones, and testosterone therapy in women -Considerations for choosing contraceptives and hormonal therapies during perimenopause -More Watch or listen (Ep. # 371) to the full episode on my website ( or your favorite podcast player.

303,435 次观看 • 1 年前

Why Alzheimer’s is a midlife disease, not a disease of old age | Lisa Mosconi, Ph.D. (Dr. Lisa Mosconi) This clip is from episode # 381 of The Drive which was released on 1/26/26. In the full episode, we cover: -What preclinical Alzheimer’s disease looks like in women: insights from advanced brain imaging into metabolic and structural changes that precede symptoms -How Alzheimer’s compares with other dementias: differences in prevalence, underlying pathology, symptom progression, and the challenges of accurate diagnosis -Hormone therapy and brain health: what the evidence suggests about menopausal hormone therapy, the legacy of the WHI, why timing and formulation matter, and how SERMs may offer a targeted approach -Reducing risk across midlife: genetics (including APOE4), modifiable lifestyle factors, sleep, metabolism, mood, and emerging therapies such as GLP-1 agonists within a long-term brain health framework Listen (Ep. # 381) to the full episode on my website ( or your favorite podcast player.

Why Alzheimer’s is a midlife disease, not a disease of old age | Lisa Mosconi, Ph.D. (Dr. Lisa Mosconi) This clip is from episode # 381 of The Drive which was released on 1/26/26. In the full episode, we cover: -What preclinical Alzheimer’s disease looks like in women: insights from advanced brain imaging into metabolic and structural changes that precede symptoms -How Alzheimer’s compares with other dementias: differences in prevalence, underlying pathology, symptom progression, and the challenges of accurate diagnosis -Hormone therapy and brain health: what the evidence suggests about menopausal hormone therapy, the legacy of the WHI, why timing and formulation matter, and how SERMs may offer a targeted approach -Reducing risk across midlife: genetics (including APOE4), modifiable lifestyle factors, sleep, metabolism, mood, and emerging therapies such as GLP-1 agonists within a long-term brain health framework Listen (Ep. # 381) to the full episode on my website ( or your favorite podcast player.

208,394 次观看 • 9 个月前

The VO₂ max you need to stay sexually active | Sally Greenwald, M.D. This clip is from episode # 371 of The Drive which was released on 11/3/25. In the full episode, we cover: -The physiology of the female orgasm, sexual comfort and satisfaction, and the disparity between men and women -Foreplay, the science of desire, and methods to help women cultivate arousal and connection -Understanding sexual desire, how to cultivate it, the role of hormones, and testosterone therapy in women -Considerations for choosing contraceptives and hormonal therapies during perimenopause -More Watch or listen (Ep. # 371) to the full episode on my website ( or your favorite podcast player.

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The VO₂ max you need to stay sexually active | Sally Greenwald, M.D. This clip is from episode # 371 of The Drive which was released on 11/3/25. In the full episode, we cover: -The physiology of the female orgasm, sexual comfort and satisfaction, and the disparity between men and women -Foreplay, the science of desire, and methods to help women cultivate arousal and connection -Understanding sexual desire, how to cultivate it, the role of hormones, and testosterone therapy in women -Considerations for choosing contraceptives and hormonal therapies during perimenopause -More Watch or listen (Ep. # 371) to the full episode on my website ( or your favorite podcast player.

231,215 次观看 • 11 个月前

The evolutionary argument against eating seed oils | Layne Norton, Ph.D. (Layne Norton, PhD) This clip is from episode # 380 of The Drive which was released on 1/19/26. In the full episode, we cover: -The core arguments against seed oils: the four main claims underlying the idea that seed oils are uniquely harmful, and how well they hold up once major confounders are addressed -The historical trials that shaped the debate: the Minnesota Coronary Experiment, Sydney Diet Heart Study, Rose Corn Oil trial, and later studies replacing saturated fat with polyunsaturated fat -Mechanisms and causality: LDL cholesterol, oxidized LDL, linoleic acid (omega-6), inflammation, -Mendelian randomization, and why lifetime LDL exposure matters more than per-particle oxidation risk -Practical takeaways: industrial processing concerns, cooking oils, real-world dietary fat choices, and how to prioritize nutrition relative to calories, activity, and overall lifestyle factors Listen (Ep. # 380) to the full episode on my website ( or your favorite podcast player.

The evolutionary argument against eating seed oils | Layne Norton, Ph.D. (Layne Norton, PhD) This clip is from episode # 380 of The Drive which was released on 1/19/26. In the full episode, we cover: -The core arguments against seed oils: the four main claims underlying the idea that seed oils are uniquely harmful, and how well they hold up once major confounders are addressed -The historical trials that shaped the debate: the Minnesota Coronary Experiment, Sydney Diet Heart Study, Rose Corn Oil trial, and later studies replacing saturated fat with polyunsaturated fat -Mechanisms and causality: LDL cholesterol, oxidized LDL, linoleic acid (omega-6), inflammation, -Mendelian randomization, and why lifetime LDL exposure matters more than per-particle oxidation risk -Practical takeaways: industrial processing concerns, cooking oils, real-world dietary fat choices, and how to prioritize nutrition relative to calories, activity, and overall lifestyle factors Listen (Ep. # 380) to the full episode on my website ( or your favorite podcast player.

100,707 次观看 • 9 个月前

The VO₂ accuracy of wearables | Peter Attia This clip is from episode # 379 of The Drive which was released on 1/12/26. In the full episode, we cover: -Use the base-and-peak model to structure your week, knowing what belongs in “base,” what belongs in “peak,” and how to combine them without breaking recovery -Choose the right approach for your time budget, with clear guidance for ~150 minutes/week, moderate training volumes, and high-volume scenarios -Execute aerobic work correctly without lab testing, including how hard it should feel, how long to hold it, and how to progress -Implement VO₂ max training the way Peter prescribes it, with clear guidance on pacing, recovery, and dosing -Measure progress knowing when lab tests matter, when field tests are enough, and why most wearable metrics mislead -Apply the framework across starting points, including beginners, metabolically unhealthy trainees, older adults, women, and higher training ages -Understand Peter’s updated thinking on zone 2 training and how recent debates do (and do not) change real-world prescriptions -Avoid the traps that waste years of training, including misapplied intensity, under-dosed volume, poor recovery, and the wrong metrics This AMA episode (Ep. # 379) is available exclusively for premium members. Become a member now to watch or listen on my website ( or your favorite podcast player.

The VO₂ accuracy of wearables | Peter Attia This clip is from episode # 379 of The Drive which was released on 1/12/26. In the full episode, we cover: -Use the base-and-peak model to structure your week, knowing what belongs in “base,” what belongs in “peak,” and how to combine them without breaking recovery -Choose the right approach for your time budget, with clear guidance for ~150 minutes/week, moderate training volumes, and high-volume scenarios -Execute aerobic work correctly without lab testing, including how hard it should feel, how long to hold it, and how to progress -Implement VO₂ max training the way Peter prescribes it, with clear guidance on pacing, recovery, and dosing -Measure progress knowing when lab tests matter, when field tests are enough, and why most wearable metrics mislead -Apply the framework across starting points, including beginners, metabolically unhealthy trainees, older adults, women, and higher training ages -Understand Peter’s updated thinking on zone 2 training and how recent debates do (and do not) change real-world prescriptions -Avoid the traps that waste years of training, including misapplied intensity, under-dosed volume, poor recovery, and the wrong metrics This AMA episode (Ep. # 379) is available exclusively for premium members. Become a member now to watch or listen on my website ( or your favorite podcast player.

97,364 次观看 • 10 个月前

Why ingredient changes don’t always mean healthier food | Layne Norton, Ph.D. (Layne Norton, PhD) This clip is from episode # 380 of The Drive which was released on 1/19/26. In the full episode, we cover: -The core arguments against seed oils: the four main claims underlying the idea that seed oils are uniquely harmful, and how well they hold up once major confounders are addressed -The historical trials that shaped the debate: the Minnesota Coronary Experiment, Sydney Diet Heart Study, Rose Corn Oil trial, and later studies replacing saturated fat with polyunsaturated fat -Mechanisms and causality: LDL cholesterol, oxidized LDL, linoleic acid (omega-6), inflammation, -Mendelian randomization, and why lifetime LDL exposure matters more than per-particle oxidation risk -Practical takeaways: industrial processing concerns, cooking oils, real-world dietary fat choices, and how to prioritize nutrition relative to calories, activity, and overall lifestyle factors Listen (Ep. # 380) to the full episode on my website ( or your favorite podcast player.

Why ingredient changes don’t always mean healthier food | Layne Norton, Ph.D. (Layne Norton, PhD) This clip is from episode # 380 of The Drive which was released on 1/19/26. In the full episode, we cover: -The core arguments against seed oils: the four main claims underlying the idea that seed oils are uniquely harmful, and how well they hold up once major confounders are addressed -The historical trials that shaped the debate: the Minnesota Coronary Experiment, Sydney Diet Heart Study, Rose Corn Oil trial, and later studies replacing saturated fat with polyunsaturated fat -Mechanisms and causality: LDL cholesterol, oxidized LDL, linoleic acid (omega-6), inflammation, -Mendelian randomization, and why lifetime LDL exposure matters more than per-particle oxidation risk -Practical takeaways: industrial processing concerns, cooking oils, real-world dietary fat choices, and how to prioritize nutrition relative to calories, activity, and overall lifestyle factors Listen (Ep. # 380) to the full episode on my website ( or your favorite podcast player.

95,127 次观看 • 9 个月前

Why higher VO₂ max is important | Peter Attia This clip is from episode # 379 of The Drive which was released on 1/12/26. In the full episode, we cover: -Use the base-and-peak model to structure your week, knowing what belongs in “base,” what belongs in “peak,” and how to combine them without breaking recovery -Choose the right approach for your time budget, with clear guidance for ~150 minutes/week, moderate training volumes, and high-volume scenarios -Execute aerobic work correctly without lab testing, including how hard it should feel, how long to hold it, and how to progress -Implement VO₂ max training the way Peter prescribes it, with clear guidance on pacing, recovery, and dosing -Measure progress knowing when lab tests matter, when field tests are enough, and why most wearable metrics mislead -Apply the framework across starting points, including beginners, metabolically unhealthy trainees, older adults, women, and higher training ages -Understand Peter’s updated thinking on zone 2 training and how recent debates do (and do not) change real-world prescriptions -Avoid the traps that waste years of training, including misapplied intensity, under-dosed volume, poor recovery, and the wrong metrics This AMA episode (Ep. # 379) is available exclusively for premium members. Become a member now to watch or listen on my website ( or your favorite podcast player.

Why higher VO₂ max is important | Peter Attia This clip is from episode # 379 of The Drive which was released on 1/12/26. In the full episode, we cover: -Use the base-and-peak model to structure your week, knowing what belongs in “base,” what belongs in “peak,” and how to combine them without breaking recovery -Choose the right approach for your time budget, with clear guidance for ~150 minutes/week, moderate training volumes, and high-volume scenarios -Execute aerobic work correctly without lab testing, including how hard it should feel, how long to hold it, and how to progress -Implement VO₂ max training the way Peter prescribes it, with clear guidance on pacing, recovery, and dosing -Measure progress knowing when lab tests matter, when field tests are enough, and why most wearable metrics mislead -Apply the framework across starting points, including beginners, metabolically unhealthy trainees, older adults, women, and higher training ages -Understand Peter’s updated thinking on zone 2 training and how recent debates do (and do not) change real-world prescriptions -Avoid the traps that waste years of training, including misapplied intensity, under-dosed volume, poor recovery, and the wrong metrics This AMA episode (Ep. # 379) is available exclusively for premium members. Become a member now to watch or listen on my website ( or your favorite podcast player.

93,440 次观看 • 10 个月前

How Older Adults Can Stop Muscle Loss | Rhonda Patrick, Ph.D. (Dr. Rhonda Patrick) This clip is from episode # 369 of The Drive which was released today (10/20/25). In the full episode, we cover: -How protein requirements evolve with age, activity, and goals, and why building muscle early is critical for long-term health -The connection between protein intake, mTOR, and longevity, and why fears around activation are largely misplaced -Why creatine’s cognitive effects may be as important as its role in physical performance -How regular heat exposure supports recovery, enhances mood, and may help protect against neurodegenerative disease -More Watch or listen (Ep. # 369) to the full episode on my website or your favorite podcast player.

How Older Adults Can Stop Muscle Loss | Rhonda Patrick, Ph.D. (Dr. Rhonda Patrick) This clip is from episode # 369 of The Drive which was released today (10/20/25). In the full episode, we cover: -How protein requirements evolve with age, activity, and goals, and why building muscle early is critical for long-term health -The connection between protein intake, mTOR, and longevity, and why fears around activation are largely misplaced -Why creatine’s cognitive effects may be as important as its role in physical performance -How regular heat exposure supports recovery, enhances mood, and may help protect against neurodegenerative disease -More Watch or listen (Ep. # 369) to the full episode on my website or your favorite podcast player.

106,292 次观看 • 1 年前

How Busy Moms Can Build Fitness Without Extra Time | Abbie Smith-Ryan, Ph.D. (Abbie Smith-Ryan PhD) This clip is from episode # 378 of The Drive which was released on 1/5/26. In the full episode, we cover: -The benefits of creatine supplementation and importance of protein intake across the menstrual cycle -How pregnancy and the postpartum period affect body composition -The biggest open questions about women’s health: combining menopause hormone therapy with exercise, GLP-1 drugs, minimizing injury risk, and more -How the training response differs between men and women, and the importance of type IIa muscle fibers Listen (Ep. # 378) to the full episode on my website ( or your favorite podcast player.

How Busy Moms Can Build Fitness Without Extra Time | Abbie Smith-Ryan, Ph.D. (Abbie Smith-Ryan PhD) This clip is from episode # 378 of The Drive which was released on 1/5/26. In the full episode, we cover: -The benefits of creatine supplementation and importance of protein intake across the menstrual cycle -How pregnancy and the postpartum period affect body composition -The biggest open questions about women’s health: combining menopause hormone therapy with exercise, GLP-1 drugs, minimizing injury risk, and more -How the training response differs between men and women, and the importance of type IIa muscle fibers Listen (Ep. # 378) to the full episode on my website ( or your favorite podcast player.

87,046 次观看 • 10 个月前

Here’s a sneak peek from episode #249 of The Drive with Andrew D. Huberman, Ph.D.. In this clip, Andrew discusses the brain's autonomic response to high-stress situations and why becoming familiar with these states can be beneficial. This episode will be released on Monday (4/3).

Here’s a sneak peek from episode #249 of The Drive with Andrew D. Huberman, Ph.D.. In this clip, Andrew discusses the brain's autonomic response to high-stress situations and why becoming familiar with these states can be beneficial. This episode will be released on Monday (4/3).

279,254 次观看 • 3 年前

I’m excited/relieved/nervous to announce that my book Outlive is officially available today. To celebrate this event, we recorded a special episode of The Drive (# 248). Order Outlive: New podcast:

I’m excited/relieved/nervous to announce that my book Outlive is officially available today. To celebrate this event, we recorded a special episode of The Drive (# 248). Order Outlive: New podcast:

268,746 次观看 • 3 年前

How Much Protein Should You Really Eat Daily? | David Allison, Ph.D. This clip is from episode # 368 of The Drive which was released today (10/13/25). In the full episode, we cover: -Why the protein RDA may be inadequate for most people and how to think about optimal intake -What current evidence shows about muscle protein synthesis and high-protein diets -The limitations and biases of nutrition research, including economic and methodological constraints -How processed and ultra-processed foods fit into the broader discussion of obesity and public health -More Watch or listen (Ep. # 368) to the full episode on my website or your favorite podcast player.

How Much Protein Should You Really Eat Daily? | David Allison, Ph.D. This clip is from episode # 368 of The Drive which was released today (10/13/25). In the full episode, we cover: -Why the protein RDA may be inadequate for most people and how to think about optimal intake -What current evidence shows about muscle protein synthesis and high-protein diets -The limitations and biases of nutrition research, including economic and methodological constraints -How processed and ultra-processed foods fit into the broader discussion of obesity and public health -More Watch or listen (Ep. # 368) to the full episode on my website or your favorite podcast player.

97,502 次观看 • 1 年前

Squatting as a Religion | Gabrielle Lyon, D.O. (Dr. Gabrielle Lyon), Mike Boyle (Mike Boyle Strength and Conditioning), and Jeff Cavaliere, M.S.P.T., C.S.C.S. (Jeff Cavaliere) This clip is from episode # 365 of The Drive which was released on 9/22/25. In the full episode, we cover: -Why so many people struggle to begin and sustain resistance training despite its proven health benefits -The essential role of nutrition and protein in shaping body composition, recovery, and long-term performance -The trade-offs between unilateral training and heavy bilateral lifts, and their impact on strength, aging, and injury risk -The long-term effects of early sports specialization in children versus the benefits of multi-sport development -More Watch or listen (Ep. # 365) to the full episode on my website (https:/peterattiamd.com/trainingforlongevity) or your favorite podcast player.

Squatting as a Religion | Gabrielle Lyon, D.O. (Dr. Gabrielle Lyon), Mike Boyle (Mike Boyle Strength and Conditioning), and Jeff Cavaliere, M.S.P.T., C.S.C.S. (Jeff Cavaliere) This clip is from episode # 365 of The Drive which was released on 9/22/25. In the full episode, we cover: -Why so many people struggle to begin and sustain resistance training despite its proven health benefits -The essential role of nutrition and protein in shaping body composition, recovery, and long-term performance -The trade-offs between unilateral training and heavy bilateral lifts, and their impact on strength, aging, and injury risk -The long-term effects of early sports specialization in children versus the benefits of multi-sport development -More Watch or listen (Ep. # 365) to the full episode on my website (https:/peterattiamd.com/trainingforlongevity) or your favorite podcast player.

95,999 次观看 • 1 年前

If you haven’t done so, please consider pre-ordering Outlive, out March 28. Lots of perks for those who preorder as discussed in this clip! Available for pre-order now wherever books are sold:

If you haven’t done so, please consider pre-ordering Outlive, out March 28. Lots of perks for those who preorder as discussed in this clip! Available for pre-order now wherever books are sold:

197,517 次观看 • 3 年前

Aging Prevention: How to Stay Ahead of Facial Aging | Tanuj Nakra, M.D. & Suzan Obagi, M.D. This clip is from episode # 355 of The Drive which was released on 6/30/25. In the full episode, we discuss: -How chronic stress accelerates facial aging -Protecting the skin: UV damage and sunscreen recommendations -Strategies for minimizing skin aging: retinoids, vitamin C, and evidence-based application methods -Effective daily skincare routine: cleansing, antioxidants, retinoids, moisturization, and more -Much more Watch or listen (Ep. # 355) to the full episode on my website ( or your favorite podcast player.

Aging Prevention: How to Stay Ahead of Facial Aging | Tanuj Nakra, M.D. & Suzan Obagi, M.D. This clip is from episode # 355 of The Drive which was released on 6/30/25. In the full episode, we discuss: -How chronic stress accelerates facial aging -Protecting the skin: UV damage and sunscreen recommendations -Strategies for minimizing skin aging: retinoids, vitamin C, and evidence-based application methods -Effective daily skincare routine: cleansing, antioxidants, retinoids, moisturization, and more -Much more Watch or listen (Ep. # 355) to the full episode on my website ( or your favorite podcast player.

85,112 次观看 • 1 年前

Why Women Should Rethink Strength Training | Gabrielle Lyon, D.O. (Dr. Gabrielle Lyon), Mike Boyle (Mike Boyle Strength and Conditioning), and Jeff Cavaliere, M.S.P.T., C.S.C.S. (Jeff Cavaliere) This clip is from episode # 365 of The Drive which was released on 9/22/25. In the full episode, we cover: -Why so many people struggle to begin and sustain resistance training despite its proven health benefits -The essential role of nutrition and protein in shaping body composition, recovery, and long-term performance -The trade-offs between unilateral training and heavy bilateral lifts, and their impact on strength, aging, and injury risk -The long-term effects of early sports specialization in children versus the benefits of multi-sport development -More Watch or listen (Ep. # 365) to the full episode on my website (https:/peterattiamd.com/trainingforlongevity) or your favorite podcast player.

Why Women Should Rethink Strength Training | Gabrielle Lyon, D.O. (Dr. Gabrielle Lyon), Mike Boyle (Mike Boyle Strength and Conditioning), and Jeff Cavaliere, M.S.P.T., C.S.C.S. (Jeff Cavaliere) This clip is from episode # 365 of The Drive which was released on 9/22/25. In the full episode, we cover: -Why so many people struggle to begin and sustain resistance training despite its proven health benefits -The essential role of nutrition and protein in shaping body composition, recovery, and long-term performance -The trade-offs between unilateral training and heavy bilateral lifts, and their impact on strength, aging, and injury risk -The long-term effects of early sports specialization in children versus the benefits of multi-sport development -More Watch or listen (Ep. # 365) to the full episode on my website (https:/peterattiamd.com/trainingforlongevity) or your favorite podcast player.

72,554 次观看 • 1 年前