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Ashlee Vance

@ashleevance • 201,076 subscribers

Writing at https://t.co/m6EtO60SiY and host of the Core Memory podcast. 2X NYT best-seller. Filmmaker @HBO (Wild, Wild Space) + @Netflix (Don't Die).

Shorts

Went off the coast of California with a fish killing robot from Shinkei yesterday. The robot kills the fish using the Japanese Ikejime technique where the brain is spiked and the gills are slit to bleed the fish. It all sounds a bit rough, but it's this versus the fish suffocating on deck for hours and being stressed. The result of the Ikejime process is much higher grade fish. Also we saw whales.

Went off the coast of California with a fish killing robot from Shinkei yesterday. The robot kills the fish using the Japanese Ikejime technique where the brain is spiked and the gills are slit to bleed the fish. It all sounds a bit rough, but it's this versus the fish suffocating on deck for hours and being stressed. The result of the Ikejime process is much higher grade fish. Also we saw whales.

50,470 views

Does your hand even spin, bro? Next level prosthetic via phantomneuro

Does your hand even spin, bro? Next level prosthetic via phantomneuro

96,325 views

Did we send Kylie Robison into Canada to play chess with Geoff Hinton? Yes, we did. Episode coming soon on

Did we send Kylie Robison into Canada to play chess with Geoff Hinton? Yes, we did. Episode coming soon on

13,588 views

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Here, in all its glory, is the exclusive first look at the massive Tesla Semi factory. Our Core Memory crew went to Nevada to see the line come to life, as it gets ready to pump out thousands of all-electric trucks. We saw the new cab and went on a drive too. Wunderbar!
10:41
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Here, in all its glory, is the exclusive first look at the massive Tesla Semi factory. Our Core Memory crew went to Nevada to see the line come to life, as it gets ready to pump out thousands of all-electric trucks. We saw the new cab and went on a drive too. Wunderbar!

Ashlee Vance

15,921,402 views • 3 months ago

Interesting that it was Grok that did the final science heavy lifting in the man cures dog's cancer with AI story. Grok corrected errors in the vaccine construct missed by Gemini Full pod down in the replies
0:38
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Interesting that it was Grok that did the final science heavy lifting in the man cures dog's cancer with AI story. Grok corrected errors in the vaccine construct missed by Gemini Full pod down in the replies

Ashlee Vance

15,018,083 views • 4 months ago

America needs to build again, and it is building. We kick off our Core Memory 4th of July American manufacturing extravaganza with the latest temple to metal built by Elon Musk and the Tesla Semi team. This is an hour+ tour of the Tesla Semi factory in Nevada alongside Dan Priestley.
1:10:36
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America needs to build again, and it is building. We kick off our Core Memory 4th of July American manufacturing extravaganza with the latest temple to metal built by Elon Musk and the Tesla Semi team. This is an hour+ tour of the Tesla Semi factory in Nevada alongside Dan Priestley.

Ashlee Vance

780,629 views • 17 days ago

We've put a whole episode of Hello World on X for the first time. Let's see what happens. Appropriately enough, it's about how Elon Musk and SpaceX reshaped LA
24:01
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We've put a whole episode of Hello World on X for the first time. Let's see what happens. Appropriately enough, it's about how Elon Musk and SpaceX reshaped LA

Ashlee Vance

15,997,658 views • 2 years ago

Alex Wang on the problems he found inside of Meta. #1, he says, was that the company lacked the AI religion of other frontier labs.
2:51
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Alex Wang on the problems he found inside of Meta. #1, he says, was that the company lacked the AI religion of other frontier labs.

Ashlee Vance

289,305 views • 2 months ago

.Vast is on a mission to replace the International Space Station, and we went to Long Beach, Calif. to check out its operations. The company is racing to get to space in 2027 with Haven-1, which will have room for four people. We saw its manufacturing operations, food labs, the whole Haven-1 design. It was an awesome trip! Full episode in the replies and on the Core Memory channel.
0:56
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.Vast is on a mission to replace the International Space Station, and we went to Long Beach, Calif. to check out its operations. The company is racing to get to space in 2027 with Haven-1, which will have room for four people. We saw its manufacturing operations, food labs, the whole Haven-1 design. It was an awesome trip! Full episode in the replies and on the Core Memory channel.

Ashlee Vance

72,436 views • 17 days ago

These guys are artists. Moment Motor takes classic cars and turns them electric. It's two to four months of work and can cost $175,000. Tons of people in tech land send their cars to Austin to get modernized. Full episode here.
11:33
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These guys are artists. Moment Motor takes classic cars and turns them electric. It's two to four months of work and can cost $175,000. Tons of people in tech land send their cars to Austin to get modernized. Full episode here.

Ashlee Vance

166,397 views • 1 month ago

.OpenAI has seen Gemini 3 and is both moved and not. We sat down with OpenAI's research chief Mark Chen for the latest on the company's thinking around rivals and what's next on the frontier
0:55
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.OpenAI has seen Gemini 3 and is both moved and not. We sat down with OpenAI's research chief Mark Chen for the latest on the company's thinking around rivals and what's next on the frontier

Ashlee Vance

744,384 views • 7 months ago

Don't think I've heard any other CEO describe agent use in such detail before. Pedro Franceschi out here running a $5bn company on OpenClaw Full episode with lots more detail in the replies
1:05
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Don't think I've heard any other CEO describe agent use in such detail before. Pedro Franceschi out here running a $5bn company on OpenClaw Full episode with lots more detail in the replies

Ashlee Vance

349,055 views • 3 months ago

We spent months following Brad Smith - aka Bradford G Smith (Brad) - on his before and after journey with a Neuralink implant. Elon Musk even popped by in this exclusive short film
12:10
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We spent months following Brad Smith - aka Bradford G Smith (Brad) - on his before and after journey with a Neuralink implant. Elon Musk even popped by in this exclusive short film

Ashlee Vance

1,235,510 views • 1 year ago

Tomorrow, Sam Altman and Greg Brockman will be on a podcast together for the first time ever. And they will give an exact date for the arrival of AGI. New models, the trial with Elon Musk, Anthropic beef, Sam personal drama, the future of compute buys, Kylie Robison and I do it all. Core Memory episode 67 hits on the Substack only. If you want the goods, it's time to sub up The Core Memory pod is on all major platforms and brought to you by Brex and @e1ventures because they have great taste.
0:31
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Tomorrow, Sam Altman and Greg Brockman will be on a podcast together for the first time ever. And they will give an exact date for the arrival of AGI. New models, the trial with Elon Musk, Anthropic beef, Sam personal drama, the future of compute buys, Kylie Robison and I do it all. Core Memory episode 67 hits on the Substack only. If you want the goods, it's time to sub up The Core Memory pod is on all major platforms and brought to you by Brex and @e1ventures because they have great taste.

Ashlee Vance

253,955 views • 3 months ago

This might be the coolest real estate business in the world. Some dudes took over a ranch in Texas and built a telescope farm. They're managing hundreds and hundreds of scopes for other people and offering super dark skies and fiber internet so that folks can take amazing pictures of space. Behold Starfront Observatories.
10:45
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This might be the coolest real estate business in the world. Some dudes took over a ranch in Texas and built a telescope farm. They're managing hundreds and hundreds of scopes for other people and offering super dark skies and fiber internet so that folks can take amazing pictures of space. Behold Starfront Observatories.

Ashlee Vance

200,376 views • 2 months ago

Some dudes took over a ranch in Texas and are trying to turn it into a manufacturing mecca. We took our cameras and spent a couple of days there. I went upside down in a plane and did a study of Texan cults. It's glorious. Welcome to Proto-Town. Full episode here. If you haven't watched our shows yet, you should. No one does tech better. Core Memory on YouTube.
23:01
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Some dudes took over a ranch in Texas and are trying to turn it into a manufacturing mecca. We took our cameras and spent a couple of days there. I went upside down in a plane and did a study of Texan cults. It's glorious. Welcome to Proto-Town. Full episode here. If you haven't watched our shows yet, you should. No one does tech better. Core Memory on YouTube.

Ashlee Vance

200,791 views • 2 months ago

Met up with Bryan Johnson at the Midjourney event for his review of David's new machine
0:41
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Met up with Bryan Johnson at the Midjourney event for his review of David's new machine

Ashlee Vance

71,730 views • 1 month ago

Our new Core Memory video on NewLimit, which is finding combinations of proteins that reverse aging across the body. It is perhaps the most exciting work in the bio-tech field. Backed by Brian Armstrong Patrick Collison John Collison Joshua Kushner Nat Friedman and others
16:57
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Our new Core Memory video on NewLimit, which is finding combinations of proteins that reverse aging across the body. It is perhaps the most exciting work in the bio-tech field. Backed by Brian Armstrong Patrick Collison John Collison Joshua Kushner Nat Friedman and others

Ashlee Vance

629,588 views • 11 months ago

New Limit just raised $435 million. This is, in part, because they've had a massive breakthrough on reversing the age of the liver with their new brand of genetic reprogramming drugs. For the first time, NewLimit's co-founder and president Jacob Kimmel details the company's breakthrough here. We also get into the longevity and bio-tech fields more broadly to explain where aging science and AI are heading. If nothing else, come to see some mice get drunk. The Core Memory podcast is available wherever you pod, and I'll put the YouTube link down below in the replies. Our show is sponsored by Brex and SendCutSend. They are both wise and benevolent. Timestamps 0:00 Intro 3:50 What Is Epigenetic Reprogramming? 7:16 Growing a Whole Animal From One Old Cell 13:06 Meet Ambrosia, the AI Hunting for Youth 22:44 $435 Million and the Race to Human Trials 29:26 The Drunk Mice That Skip the Hangover 36:48 Inside the First Human Trial 43:14 Will There Ever Be a Hangover Pen? 49:39 Beyond the Liver: The Delivery Problem 1:03:27 Answering the Skeptics 1:12:42 Will OpenAI Become a Drug Company? 1:23:53 The Health Story Bigger Than AI? 1:35:00 How Far Behind Is the US vs China? 1:53:10 Can We Build Computers From Neurons?
2:00:28
ashleevance's profile picture

New Limit just raised $435 million. This is, in part, because they've had a massive breakthrough on reversing the age of the liver with their new brand of genetic reprogramming drugs. For the first time, NewLimit's co-founder and president Jacob Kimmel details the company's breakthrough here. We also get into the longevity and bio-tech fields more broadly to explain where aging science and AI are heading. If nothing else, come to see some mice get drunk. The Core Memory podcast is available wherever you pod, and I'll put the YouTube link down below in the replies. Our show is sponsored by Brex and SendCutSend. They are both wise and benevolent. Timestamps 0:00 Intro 3:50 What Is Epigenetic Reprogramming? 7:16 Growing a Whole Animal From One Old Cell 13:06 Meet Ambrosia, the AI Hunting for Youth 22:44 $435 Million and the Race to Human Trials 29:26 The Drunk Mice That Skip the Hangover 36:48 Inside the First Human Trial 43:14 Will There Ever Be a Hangover Pen? 49:39 Beyond the Liver: The Delivery Problem 1:03:27 Answering the Skeptics 1:12:42 Will OpenAI Become a Drug Company? 1:23:53 The Health Story Bigger Than AI? 1:35:00 How Far Behind Is the US vs China? 1:53:10 Can We Build Computers From Neurons?

Ashlee Vance

93,172 views • 1 month ago

New England's tech scene can feel sedate compared to the wilds of California. But, if you know where to look, there are rather astonishing treasures to be found. We invaded Boston and New Haven to find you actual brains in vats, new submarines, cancer cures and the world's best coffee. Timestamps 00:00 Intro 01:11 The Best Coffee on the Planet? 09:37 A $451 Million Family Secret 12:30 Anduril's Robot Submarine 17:32 What's Hiding on the Ocean Floor? 21:23 Brains in Vats. Yes, Real Ones 29:22 A Croatian Dinner With the Brain Guys 33:36 Curing Cancer With Code
42:46
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New England's tech scene can feel sedate compared to the wilds of California. But, if you know where to look, there are rather astonishing treasures to be found. We invaded Boston and New Haven to find you actual brains in vats, new submarines, cancer cures and the world's best coffee. Timestamps 00:00 Intro 01:11 The Best Coffee on the Planet? 09:37 A $451 Million Family Secret 12:30 Anduril's Robot Submarine 17:32 What's Hiding on the Ocean Floor? 21:23 Brains in Vats. Yes, Real Ones 29:22 A Croatian Dinner With the Brain Guys 33:36 Curing Cancer With Code

Ashlee Vance

42,946 views • 24 days ago

Meta paid $14 billion to pry Alex Wang away from Scale AI, the company he co-founded and ran. The hope - Zuck's hope - was that Wang could fix what ailed Meta's AI program. Over the past year, Meta has spent billions more pulling researchers away from other labs and has raced to create it first new model called Muse Spark under a regime led by Wang, Nat Friedman, Daniel Gross and Shengjia Zhao. This interview is the first time Wang has talked about all the drama of the past year and where Meta is heading with AI. The Core Memory podcast is on Apple, Spotify, YouTube and all major platforms. Enjoy! Timestamps 00:00 Intro 02:02 Inside Meta Superintelligence Labs 06:23 The Tahoe Conversation 12:50 How Do You Rebuild a Frontier Lab 24:35 The Soup and Being "Too Young" 32:48 MuseSpark: Appetizer, Not Entrée 48:47 Why Does Everyone Hate AI? 53:50 Open Source and the Manus Question 1:04:59 Robots and Mango 1:11:08 Sci-Fi, BCI, and Do AI Models Deserve Moral Weight?
1:23:00
ashleevance's profile picture

Meta paid $14 billion to pry Alex Wang away from Scale AI, the company he co-founded and ran. The hope - Zuck's hope - was that Wang could fix what ailed Meta's AI program. Over the past year, Meta has spent billions more pulling researchers away from other labs and has raced to create it first new model called Muse Spark under a regime led by Wang, Nat Friedman, Daniel Gross and Shengjia Zhao. This interview is the first time Wang has talked about all the drama of the past year and where Meta is heading with AI. The Core Memory podcast is on Apple, Spotify, YouTube and all major platforms. Enjoy! Timestamps 00:00 Intro 02:02 Inside Meta Superintelligence Labs 06:23 The Tahoe Conversation 12:50 How Do You Rebuild a Frontier Lab 24:35 The Soup and Being "Too Young" 32:48 MuseSpark: Appetizer, Not Entrée 48:47 Why Does Everyone Hate AI? 53:50 Open Source and the Manus Question 1:04:59 Robots and Mango 1:11:08 Sci-Fi, BCI, and Do AI Models Deserve Moral Weight?

Ashlee Vance

97,018 views • 2 months ago

Spent six years making this sucker . Hope you guys enjoy. Coming to HBO on July 17
2:01
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Spent six years making this sucker . Hope you guys enjoy. Coming to HBO on July 17

Ashlee Vance

792,245 views • 2 years ago

There's a race to get the first commercial space station up in orbit. Boosted by an original $1 billion investment from Jed McCaleb, Vast has been sprinting to get to space first. We went to Long Beach to check out Vast's Haven-1 space station that could fly next year and to see what a more modern space station looks like. Enjoy!!
21:28
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There's a race to get the first commercial space station up in orbit. Boosted by an original $1 billion investment from Jed McCaleb, Vast has been sprinting to get to space first. We went to Long Beach to check out Vast's Haven-1 space station that could fly next year and to see what a more modern space station looks like. Enjoy!!

Ashlee Vance

20,787 views • 14 days ago