Loading video...

Video Failed to Load

There was a problem loading this video. This could be due to a temporary network issue or the video might be unavailable.

Our new Core Memory video on NewLimit, which is finding combinations of proteins that reverse aging across the body. It is perhaps the most exciting work in the bio-tech field. Backed by Brian Armstrong Patrick Collison John Collison Joshua Kushner Nat Friedman and others

Ashlee Vance

200,260 subscribers

629,588 views • 1 year ago •via X (Twitter)

Health & Wellness Science & Technology Education

Anya Rossi• Live Now

Private livecam show

0 Comments

No comments available

Comments from the original post will appear here

Related Videos

20 years ago, every founder feared one tech company: Google. Even when Patrick Collison (CEO of Stripe) was building a startup back then, he got the same question in every meeting: "What if Google does this ?" But the truth is, Google still didn't build most of what people expected. Because no company can chase 100 priorities at once. Cause the teams get in each other's way, and everything slows down. Today the same question is aimed at the AI labs. Patrick is honest that better models will wipe out some products. That part is real. But the fear is far bigger than the record deserves. — Patrick Collison (.Patrick Collison), founder of Stripe, at Y Combinator's startup school

20 years ago, every founder feared one tech company: Google. Even when Patrick Collison (CEO of Stripe) was building a startup back then, he got the same question in every meeting: "What if Google does this ?" But the truth is, Google still didn't build most of what people expected. Because no company can chase 100 priorities at once. Cause the teams get in each other's way, and everything slows down. Today the same question is aimed at the AI labs. Patrick is honest that better models will wipe out some products. That part is real. But the fear is far bigger than the record deserves. — Patrick Collison (.Patrick Collison), founder of Stripe, at Y Combinator's startup school

GeniusThinking

113,494 views • 13 days ago

New business creation on Stripe is up almost 2x year over year. Our founder Amjad Masad sat down with Patrick Collison to talk about what's driving it, who's winning, and why entrepreneurship is the most under-appreciated economic story right now.

New business creation on Stripe is up almost 2x year over year. Our founder Amjad Masad sat down with Patrick Collison to talk about what's driving it, who's winning, and why entrepreneurship is the most under-appreciated economic story right now.

Replit ⠕

20,318 views • 3 months ago

Patrick Collison on what changes when biology becomes programmable: "We, humanity, have never cured a complex disease." "Most cardiovascular disease, most cancers, most autoimmune disease, most neurodegenerative disease... For none of them can we really say that we've cured it, that we understand the causal pathways in meaningful detail." "Then over the last 10 ish years... we’ve gotten three new classes of technology in biology." "If you put those together, you now have the ability… to read, think, and to write. And this starts to really feel like a new kind of Turing loop." Patrick Collison with Michael Truell

Patrick Collison on what changes when biology becomes programmable: "We, humanity, have never cured a complex disease." "Most cardiovascular disease, most cancers, most autoimmune disease, most neurodegenerative disease... For none of them can we really say that we've cured it, that we understand the causal pathways in meaningful detail." "Then over the last 10 ish years... we’ve gotten three new classes of technology in biology." "If you put those together, you now have the ability… to read, think, and to write. And this starts to really feel like a new kind of Turing loop." Patrick Collison with Michael Truell

a16z

120,120 views • 6 months ago

Founder of Bridge Zach Abrams tells a Stripe acquisition story: “I walked into Stripe to meet John Collison and Patrick Collison. First thing John says: 'Can I tell you a joke? What’s the difference between a bank and Tether? … One of them is this big institution that holds a ton of money and you have no idea where it is, and if you want your money back you might not be able to… and the other one is a stablecoin.’”

Founder of Bridge Zach Abrams tells a Stripe acquisition story: “I walked into Stripe to meet John Collison and Patrick Collison. First thing John says: 'Can I tell you a joke? What’s the difference between a bank and Tether? … One of them is this big institution that holds a ton of money and you have no idea where it is, and if you want your money back you might not be able to… and the other one is a stablecoin.’”

Bankless

59,908 views • 11 months ago

We’re thrilled to announce our $23M Series A led by Sequoia Capital - joined by Patrick Collison, John Collison, and david. Honored to welcome Roelof Botha to our board. We’ve entered a new era of manufacturing. Reusable rockets. Humanoid robots. Self-driving cars. Humanity is reinventing how it builds. We started by building hybrid rocket engines. Along the way, we built tools that made us move faster - design, build, test, iterate. Those tools became Flow Engineering. Today, Flow has become the default platform for next-gen hardware teams, powering the systems that will define our future.

We’re thrilled to announce our $23M Series A led by Sequoia Capital - joined by Patrick Collison, John Collison, and david. Honored to welcome Roelof Botha to our board. We’ve entered a new era of manufacturing. Reusable rockets. Humanoid robots. Self-driving cars. Humanity is reinventing how it builds. We started by building hybrid rocket engines. Along the way, we built tools that made us move faster - design, build, test, iterate. Those tools became Flow Engineering. Today, Flow has become the default platform for next-gen hardware teams, powering the systems that will define our future.

Pari Singh

558,758 views • 10 months ago

11/ This is not a small problem. Stripe handles more than a trillion dollars in payments every year. Millions of businesses rely on their tech. If they can put a “hold” on my money for no reason, they can do it to anyone. Is that the plan Patrick Collison?

11/ This is not a small problem. Stripe handles more than a trillion dollars in payments every year. Millions of businesses rely on their tech. If they can put a “hold” on my money for no reason, they can do it to anyone. Is that the plan Patrick Collison?

Michael Knowles

212,513 views • 1 year ago

Patrick Collison, CEO of Stripe, on why the lean startup playbook is dead in the AI era: "maybe you have to more aggressively decorrelate in the era of AI." "Many of the companies that are most successful over the last 10 years, so many of them are very anti-lean startup."

Patrick Collison, CEO of Stripe, on why the lean startup playbook is dead in the AI era: "maybe you have to more aggressively decorrelate in the era of AI." "Many of the companies that are most successful over the last 10 years, so many of them are very anti-lean startup."

Guillermo Flor

304,666 views • 18 days ago

.Thrive Capital’s Philip Clark and Joshua Kushner flew into an active war zone in Israel to invest in Wiz: “The philosophy at Thrive that Josh taught me is: the people that win deals are the people that want to win deals most.” “We have a ‘leave it all on the field’ mentality.”

.Thrive Capital’s Philip Clark and Joshua Kushner flew into an active war zone in Israel to invest in Wiz: “The philosophy at Thrive that Josh taught me is: the people that win deals are the people that want to win deals most.” “We have a ‘leave it all on the field’ mentality.”

sourcery

115,174 views • 5 months ago

The biggest startup advice (The Lean Startup Method) you've been following is broken. 1) Launch something small and cheap 2) Win one narrow group of users 3) Grow outward slowly Patrick Collison (CEO of Stripe) says it was only relevant 20 years ago, for two reasons he names: A) Raising money back then was genuinely hard B) And nothing let you spin up a company able to do many things at once But today, AI removed both limits. Which is why he thinks you can now start something far more ambitious on day one. Look at who actually won the last decade. The AI labs. Anduril, the defence company. So many of them did the opposite of lean. If your plan feels too small, check whose advice you're following. — Patrick Collison (.Patrick Collison), founder of Stripe, at Y Combinator's startup school

The biggest startup advice (The Lean Startup Method) you've been following is broken. 1) Launch something small and cheap 2) Win one narrow group of users 3) Grow outward slowly Patrick Collison (CEO of Stripe) says it was only relevant 20 years ago, for two reasons he names: A) Raising money back then was genuinely hard B) And nothing let you spin up a company able to do many things at once But today, AI removed both limits. Which is why he thinks you can now start something far more ambitious on day one. Look at who actually won the last decade. The AI labs. Anduril, the defence company. So many of them did the opposite of lean. If your plan feels too small, check whose advice you're following. — Patrick Collison (.Patrick Collison), founder of Stripe, at Y Combinator's startup school

GeniusThinking

27,669 views • 12 days ago

Flexport CEO Ryan Petersen still thinks about a 2012 essay written by Paul Graham called 'Schlep Blindness.' Every startup founder of a certain era of went through the misery of applying to accept credit card payments. But only Patrick and John Collison (Patrick Collison and John Collison) started Stripe. "There was a $100 billion opportunity available to every entrepreneur," says Petersen. "The worst problems in your life, your conscious brain is unable to focus, to think about them at all. You're just completely blind that this problem exists." More recently, Petersen (Ryan Petersen) says that PG (Paul Graham) has described his company, Flexport, the same way. "Anyone who ever imported anything wen through this pain, saw it's a nightmare to fill out paperwork, and no one call tell you where your stuff is, or when it's going to arrive." Catch the full discussion on The Upstarts Podcast 👇 YouTube: Spotify: Apple:

Flexport CEO Ryan Petersen still thinks about a 2012 essay written by Paul Graham called 'Schlep Blindness.' Every startup founder of a certain era of went through the misery of applying to accept credit card payments. But only Patrick and John Collison (Patrick Collison and John Collison) started Stripe. "There was a $100 billion opportunity available to every entrepreneur," says Petersen. "The worst problems in your life, your conscious brain is unable to focus, to think about them at all. You're just completely blind that this problem exists." More recently, Petersen (Ryan Petersen) says that PG (Paul Graham) has described his company, Flexport, the same way. "Anyone who ever imported anything wen through this pain, saw it's a nightmare to fill out paperwork, and no one call tell you where your stuff is, or when it's going to arrive." Catch the full discussion on The Upstarts Podcast 👇 YouTube: Spotify: Apple:

Alex Konrad

69,560 views • 5 months ago

NEW EPISODE: “Bitcoin is special and unique in the sense that it is like digital gold. It has the highest trust because it's the original incarnation of crypto. It was truly a computer science breakthrough.” -Brian Armstrong, Coinbase

NEW EPISODE: “Bitcoin is special and unique in the sense that it is like digital gold. It has the highest trust because it's the original incarnation of crypto. It was truly a computer science breakthrough.” -Brian Armstrong, Coinbase

Tetragrammaton

165,631 views • 7 months ago

Our new song, “Choo Choo,” is available now all over the world. This is the 2nd single from our new record, “Something Worth Waiting For,” which will be out on April 24th. Video by Stas Slyvka Photograph by Adam Powell Links to the song and the music video are in our bio.

Our new song, “Choo Choo,” is available now all over the world. This is the 2nd single from our new record, “Something Worth Waiting For,” which will be out on April 24th. Video by Stas Slyvka Photograph by Adam Powell Links to the song and the music video are in our bio.

Friko

23,399 views • 5 months ago

SendCutSend founder Jim Belosic just raised $110M from Patrick Collison and John Collison, Andrew Reed, and Matt Huang to do "the Amazon of manufacturing." The idea for the deal started after he got introduced to Patrick on 𝕏. "He was like, 'Oh yeah, I've heard about your company. You guys sound awesome. I'll invest.'" "I was like, 'That sounds amazing. Thank you. How does this work? I don't know how investment works.'" "It became this dream team, and I was like, 'If I don't do it now, I don't know if I'll ever be able to put this together again.'" Jim tells the story:

SendCutSend founder Jim Belosic just raised $110M from Patrick Collison and John Collison, Andrew Reed, and Matt Huang to do "the Amazon of manufacturing." The idea for the deal started after he got introduced to Patrick on 𝕏. "He was like, 'Oh yeah, I've heard about your company. You guys sound awesome. I'll invest.'" "I was like, 'That sounds amazing. Thank you. How does this work? I don't know how investment works.'" "It became this dream team, and I was like, 'If I don't do it now, I don't know if I'll ever be able to put this together again.'" Jim tells the story:

TBPN

132,932 views • 3 months ago

STARSEEDS AGE IN REVERSE …it is not a legend… Did you know that ? It’s disconcerting, and most of you are completely thrown off… You don’t understand what’s happening inside you… You’re getting younger… Your body is aging more slowly, and a spirit is animating it more and more. Listen carefully to the video all the way to the end… “he gives a key.“

STARSEEDS AGE IN REVERSE …it is not a legend… Did you know that ? It’s disconcerting, and most of you are completely thrown off… You don’t understand what’s happening inside you… You’re getting younger… Your body is aging more slowly, and a spirit is animating it more and more. Listen carefully to the video all the way to the end… “he gives a key.“

AuroraArabella

24,120 views • 3 months ago

🚨 NEW EPISODE FOR EUROPE'S MOST AMBITIOUS STARTUPS 🇪🇺 And this might easily be the best video we have done so far! The company, their product and the team is just insane. The goal of this company is to make money out of thin air – literally. No joke. TLDR: Heavy machinery, in the middle of London, easily one of the most cracked team is met in a while, and their first test site? A military base. What's crazy to me is that they are so heads down that nobody knows them yet… but still they already raised GBP 10M+ from the founders of stripe (Patrick Collison John Collison), Nat Friedman, Harry Stebbings, Pietro Invernizzi, taavet hinrikus and Plural and many more. The Company is RIVAN – Rivan Their product? Getting the CO2 out of the air and combine it with H2 from water -> to create gas, which they directly pump into the network grid to make money. The same kind of gas we currently have to pay Russia for… we fight wars for… just without drilling into the ground and releasing CO2, but "mining the sky" instead! This kind of tech is still in early stages – and tons of hypotheses have to be validated – but in the next five years the math can work out and if there's a team to figure this out, it's this one. I took my camera and visited Harvey Hodd and his team in their warehouse office in London and joined him to their first test site on a military base. I am a big fan of this guy. Intensity, obsession, technical competence. And the whole team is like this. In the video you will see how everything works… every machine… but also how they keep urgency in the team… how they pay people to move closer to the office… why they are already running a military base only a few months in… how this can even ever work economically… and how the hell do you avoid everything blowing up – literally. RIVAN – You can watch the full video on the youtube channel: Please RT + LIKE here and comment/share/like on youtube too please! Every little bit of engagement helps in youtube's algorithm! Let's frigging go! 👇

🚨 NEW EPISODE FOR EUROPE'S MOST AMBITIOUS STARTUPS 🇪🇺 And this might easily be the best video we have done so far! The company, their product and the team is just insane. The goal of this company is to make money out of thin air – literally. No joke. TLDR: Heavy machinery, in the middle of London, easily one of the most cracked team is met in a while, and their first test site? A military base. What's crazy to me is that they are so heads down that nobody knows them yet… but still they already raised GBP 10M+ from the founders of stripe (Patrick Collison John Collison), Nat Friedman, Harry Stebbings, Pietro Invernizzi, taavet hinrikus and Plural and many more. The Company is RIVAN – Rivan Their product? Getting the CO2 out of the air and combine it with H2 from water -> to create gas, which they directly pump into the network grid to make money. The same kind of gas we currently have to pay Russia for… we fight wars for… just without drilling into the ground and releasing CO2, but "mining the sky" instead! This kind of tech is still in early stages – and tons of hypotheses have to be validated – but in the next five years the math can work out and if there's a team to figure this out, it's this one. I took my camera and visited Harvey Hodd and his team in their warehouse office in London and joined him to their first test site on a military base. I am a big fan of this guy. Intensity, obsession, technical competence. And the whole team is like this. In the video you will see how everything works… every machine… but also how they keep urgency in the team… how they pay people to move closer to the office… why they are already running a military base only a few months in… how this can even ever work economically… and how the hell do you avoid everything blowing up – literally. RIVAN – You can watch the full video on the youtube channel: Please RT + LIKE here and comment/share/like on youtube too please! Every little bit of engagement helps in youtube's algorithm! Let's frigging go! 👇

Andreas Klinger 🦾

21,882 views • 1 year ago