HHMI | Janelia

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A pioneering research center where scientists from many disciplines collaborate on science's most challenging problems. https://t.co/Jeu3KqBBI9

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HHMI | Janelia

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🥳 Happy #DNADay! 🧬 What better way to celebrate than with cycleHCR: one of our newest tools, developed by the Liu Lab, that uses a novel DNA barcode system to track hundreds of RNA &amp; protein molecules in single cells within thick biological samples ➡️

🔬 A new probe developed by Janelia researchers &amp; collaborators that enables visualization of extracellular matrix structure in live tissues could also be useful in studying diseases linked to changes in the extracellular matrix and in diagnostic imaging➡️

🧠 By tracking the activity of thousands of neurons over days &amp; weeks during learning, Janelia researchers led by Weinan Sun Johan Winnubst &amp; Nelson Spruston have systematically detailed, step by step, how cognitive maps form in the brain’s hippocampus. 🗺️

📢 Submissions are now open for the CellMap Segmentation Challenge. Build the best method for segmenting cellular organelles in vEM using our 289 annotated volumes, 40 organelle classes, and 22 diverse cell and tissue types. 🔗

🗺️ A new aging atlas developed by the Wang Lab (meng wang) &amp; collaborators BCMHouston Creighton University gives scientists an in-depth view of how individual cells &amp; tissues in worms age &amp; how different lifespan-extending strategies might stop the clock. ⌛ ➡️

🔬 A new method developed by Janelia researchers &amp; collaborators uses a polarized dual-view light microscope &amp; a new way to represent groups of oriented molecules to simultaneously image the location &amp; orientation of biomolecules in 3D.

In a new review, Group Leaders Carsen Stringer @[email protected] &amp; Marius Pachitariu examine methods for analyzing large-scale neuronal recordings, how these tools have enabled progress in answering longstanding questions in neuroscience, and what advances &amp; challenges lie ahead.

Videos

Watch Anya Live

🦟 By infusing a virtual fruit fly with artificial intelligence, HHMI | Janelia and Google DeepMind scientists have created a computerized insect that can walk and fly just like the real thing. 🤖 🔗

🧬A new imaging technique developed by the Liu Lab uses a novel DNA barcode system to track hundreds of RNA &amp; protein molecules in single cells within thick biological samples, providing a full picture of how these structures are organized inside tissues.

🧠 A new wiring diagram of the 166,000+ neurons in the brain &amp; nerve cord of a male fruit fly is a key tool in uncovering how the brain enables complex behavior—information that could ultimately help scientists understand what causes different diseases ➡️

🪰 A team of researchers has unveiled the complete connectome of a male fruit fly central nervous system—a seamless map of all the neurons in the brain and nerve cord of a single male fruit fly and the millions of connections between them. 🔗

🧠 Janelia researchers have mapped out the step-by-step process of cognitive map formation in the brain’s hippocampus during learning and identified the type of mathematical model that best reproduces this learning process ➡️

🔬 The Shroff Lab &amp; collaborators have developed a new AI method that produces sharp microscopy images throughout a thick biological sample without using adaptive optics, adding additional hardware, or taking more images. 🔗

🥼 Janelia researchers led by Boaz Mohar (@[email protected]), Nelson Spruston, Luke Lavis &amp; karel svoboda allen institute have developed a new imaging tool that maps brain-wide changes in neuronal connections. 🧠 🔗

🐟 Discouraged zebrafish are helping scientists understand how ketamine works in the brain. 🧠 🥼 New research from Misha Ahrens, Marc Duque Ramírez, Alex Chen, Eric Hsu, Dwight Bergles, Mark Fishman &amp; Florian Engert. 🔗

Introducing PetaKit5D: a comprehensive suite of software tools for processing petabyte-scale microscopy data from Janelia Sr Fellow/HHMI Investigator Eric Betzig, Xiongtao Ruan, Matthew Mueller, Srigokul Upadhyayula Advanced Bioimaging Center @ UC Berkeley UC Berkeley &amp; colleagues

In a new review, Group Leaders Carsen Stringer @[email protected] &amp; Marius Pachitariu examine methods for analyzing large-scale neuronal recordings, how these tools have enabled progress in answering longstanding questions in neuroscience, and what advances &amp; challenges lie ahead.

🎓Recent PhD looking for the next step in your career? Postdocs at Janelia are part of a vibrant scientific community, working with &amp; learning from experts across a variety of fields in a collaborative &amp; supportive environment. Janelia #postdoclife ➡️

🥳 Happy #DNADay! 🧬 What better way to celebrate than with cycleHCR: one of our newest tools, developed by the Liu Lab, that uses a novel DNA barcode system to track hundreds of RNA & protein molecules in single cells within thick biological samples ➡️

🔬 A new probe developed by Janelia researchers & collaborators that enables visualization of extracellular matrix structure in live tissues could also be useful in studying diseases linked to changes in the extracellular matrix and in diagnostic imaging➡️

🧠 By tracking the activity of thousands of neurons over days & weeks during learning, Janelia researchers led by Weinan Sun Johan Winnubst & Nelson Spruston have systematically detailed, step by step, how cognitive maps form in the brain’s hippocampus. 🗺️

🗺️ A new aging atlas developed by the Wang Lab (meng wang) & collaborators BCMHouston Creighton University gives scientists an in-depth view of how individual cells & tissues in worms age & how different lifespan-extending strategies might stop the clock. ⌛ ➡️

🔬 A new method developed by Janelia researchers & collaborators uses a polarized dual-view light microscope & a new way to represent groups of oriented molecules to simultaneously image the location & orientation of biomolecules in 3D.

In a new review, Group Leaders Carsen Stringer @[email protected] & Marius Pachitariu examine methods for analyzing large-scale neuronal recordings, how these tools have enabled progress in answering longstanding questions in neuroscience, and what advances & challenges lie ahead.

🧬A new imaging technique developed by the Liu Lab uses a novel DNA barcode system to track hundreds of RNA & protein molecules in single cells within thick biological samples, providing a full picture of how these structures are organized inside tissues.

🧠 A new wiring diagram of the 166,000+ neurons in the brain & nerve cord of a male fruit fly is a key tool in uncovering how the brain enables complex behavior—information that could ultimately help scientists understand what causes different diseases ➡️

🔬 The Shroff Lab & collaborators have developed a new AI method that produces sharp microscopy images throughout a thick biological sample without using adaptive optics, adding additional hardware, or taking more images. 🔗

🥼 Janelia researchers led by Boaz Mohar (@[email protected]), Nelson Spruston, Luke Lavis & karel svoboda allen institute have developed a new imaging tool that maps brain-wide changes in neuronal connections. 🧠 🔗

🐟 Discouraged zebrafish are helping scientists understand how ketamine works in the brain. 🧠 🥼 New research from Misha Ahrens, Marc Duque Ramírez, Alex Chen, Eric Hsu, Dwight Bergles, Mark Fishman & Florian Engert. 🔗

Introducing PetaKit5D: a comprehensive suite of software tools for processing petabyte-scale microscopy data from Janelia Sr Fellow/HHMI Investigator Eric Betzig, Xiongtao Ruan, Matthew Mueller, Srigokul Upadhyayula Advanced Bioimaging Center @ UC Berkeley UC Berkeley & colleagues

In a new review, Group Leaders Carsen Stringer @[email protected] & Marius Pachitariu examine methods for analyzing large-scale neuronal recordings, how these tools have enabled progress in answering longstanding questions in neuroscience, and what advances & challenges lie ahead.

🎓Recent PhD looking for the next step in your career? Postdocs at Janelia are part of a vibrant scientific community, working with & learning from experts across a variety of fields in a collaborative & supportive environment. Janelia #postdoclife ➡️