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Profluent

@ProfluentBio • 3,968 subscribers

Grounded in nature, authored by AI

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Protein language models just got an upgrade. Meet Profluent-E1: a free, flexible, frontier protein sequence encoder. E1 is built with retrieval augmentation to learn from multiple sequences. Models trained over 4T tokens with only 150M-600M params, E1 is SOTA for zero-shot functional and unsupervised structural tasks. It raises the bar for protein representation learning and is freely available today.

Protein language models just got an upgrade. Meet Profluent-E1: a free, flexible, frontier protein sequence encoder. E1 is built with retrieval augmentation to learn from multiple sequences. Models trained over 4T tokens with only 150M-600M params, E1 is SOTA for zero-shot functional and unsupervised structural tasks. It raises the bar for protein representation learning and is freely available today.

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We’re excited to share new data published in nature detailing the impressive activity, specificity, and low immunogenicity of our AI-designed CRISPR-Cas proteins, including OpenCRISPR-1. The future of gene editing is here and we’re scaling our capabilities to tackle the hardest problems that will unlock new medicines.

We’re excited to share new data published in nature detailing the impressive activity, specificity, and low immunogenicity of our AI-designed CRISPR-Cas proteins, including OpenCRISPR-1. The future of gene editing is here and we’re scaling our capabilities to tackle the hardest problems that will unlock new medicines.

101,858 Aufrufe • vor 10 Monaten

We’re excited to share our latest work published today in Nature Biotechnology: Protein2PAM, an AI model that enables the rapid design of CRISPR editors with new PAM recognition And we’re making the model freely available for research and commercial use:

We’re excited to share our latest work published today in Nature Biotechnology: Protein2PAM, an AI model that enables the rapid design of CRISPR editors with new PAM recognition And we’re making the model freely available for research and commercial use:

16,511 Aufrufe • vor 4 Monaten

There’s always been a tension between addressing rare diseases and making the economics work. At Profluent, we believe that AI can be the equalizer, making it possible to design personalized genomic medicines and democratize the field of gene editing. Learn more about our partnership with the Rett Syndrome Research Trust:

There’s always been a tension between addressing rare diseases and making the economics work. At Profluent, we believe that AI can be the equalizer, making it possible to design personalized genomic medicines and democratize the field of gene editing. Learn more about our partnership with the Rett Syndrome Research Trust:

12,517 Aufrufe • vor 6 Monaten

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