no.mind
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Unlock mitochondrial energy, hormonal supremacy & peak cognition | The hidden advantage they don’t want you to have ↓ | Ex-Law • Ex-Tech Sales
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Shopify billionaire co-founder & CEO Tobi Lütke — one of the most analytically rigorous founders alive — uses affirmations. His exact words: "If you tell yourself or write down something about yourself 100 times, it writes into the neurofrontal cortex at such a deep level that your brain will start reconciling you to that. It just works." His personal example: He was terrified of public speaking. For one week he sat down every day for 10 minutes and wrote: "I love public speaking." A week later the fear was gone. "It's not like a placebo. You just actively change your neurofrontal cortex in this moment." Your brain starts shaping your behavior around the identity you rehearse most.
no.mind4,378,041 просмотров • 2 месяцев назад
Mark Zuckerberg says his daily caffeine intake is zero. On Theo Von's podcast, when asked whether he drinks coffee, he said: "Nah." He said he might drink it occasionally on vacation, recreationally, almost like a celebration. Then he started explaining why: "I just hate anything that messes with... I don't like any kind of chemicals or anything like that." When I heard that, I had to smile. Did he want to say: Anything that messes with my perception? My mind? My consciousness? My brain?
no.mind344,027 просмотров • 23 дней назад
Caffeine cuts blood flow to the brain by 30%. Psychiatrist Daniel Amen says anything that lowers blood flow prematurely ages the organ. He founded Amen Clinics, which has performed over 200,000 brain SPECT scans. In his scans, low blood flow is linked to depression, ADHD, substance use problems and traumatic brain injury. He says it’s the top imaging predictor of Alzheimer’s. On SPECT, he says, caffeine constricts blood flow by 30%. The effect is large enough that he has patients avoid caffeine the morning of a scan. Otherwise it artificially lowers the reading. Blood flow is not his only reason. Caffeine blocks adenosine and disrupts sleep. It is addictive and causes withdrawal. It raises cortisol. His position: caffeine is best limited or avoided for optimal brain function. And the patients who quit tell him the same thing: “So many of my patients stop, and uniformly they tell me they feel better. They said their energy is better.” One of them was Jeff, a pilot with brain fog and memory problems. Jeff was having around 600 mg of caffeine per day (less than two Venti brewed coffees from Starbucks, at ~330 mg each). His brain looked terrible. They cut his caffeine by 5% a day. In three weeks it was gone, with no withdrawal and no headaches. Then the texts from Jeff came in: “Unbelievable energy. Unbelievable clarity.” People treat caffeine addiction as one of life’s little miracles, with no cost. Amen’s scans tell a different story.
no.mind269,031 просмотров • 22 дней назад
A banana in a Polish January delivers summer’s deuterium without summer’s light. The entire food web is tied to light cycles. Summer at 52°N means long days, strong sunlight & carbohydrate availability from fruits, berries & honey. By January, nothing is growing outside in Poland. Deuterium is a big part of why that matters. It is the heavy isotope of hydrogen, with one extra neutron that makes it twice as heavy. Your mitochondria contain ATP synthase nanomotors spinning at roughly 9,000 rpm to produce ATP, driven by hydrogen ions flowing through them. When deuterium reaches the motor in place of regular hydrogen, the extra mass disrupts its rotation & the motor stutters. László Boros, a Hungarian medical doctor & retired UCLA professor who studies deuterium, compares it to giving a juggler a ball that is suddenly twice as heavy. Carbohydrates carry the most deuterium, protein sits in the middle & animal fats carry the least: Coconut water ~155 ppm. Wheat flour ~150 ppm. Banana ~149 ppm. Potatoes ~142 ppm. Beef ~138 ppm. Butter ~124 ppm. Beef fat ~121 ppm. In summer, or closer to the equator, higher-deuterium foods arrive together with much stronger red & near-infrared light. That light reduces the viscosity of interfacial water inside the mitochondrial matrix. The nanomotors then rotate more freely & produce ATP more efficiently, even when dietary deuterium is higher. At 52°N in winter, that photon pressure drops dramatically, & the food signal has to change with it. So in winter, I eat fewer carbs, keep them local & shift more toward protein & fat.
no.mind15,664 просмотров • 2 дней назад
Caffeine is psychoactive at doses below 20 mg. For many people, 10 mg or less. That is a couple sips of coffee. Switching from coffee to tea or decaf is not quitting caffeine. Roland Griffiths of Johns Hopkins — one of the leading caffeine researchers in the world — found that caffeine is behaviorally active at doses far lower than anyone previously knew. His exact words: “One of the interesting things that we showed in the course of that research is that caffeine is behaviorally active at doses far lower than anyone ever knew previously. Many people can detect the effects of caffeine at doses of less than 20 milligrams, and many 10 or less milligrams. So a couple of sips of coffee can produce reliable, detectable, subjective effects. And these are really rigorous blinded studies.” This is why the common alternatives don’t get you to zero. Black tea and green tea contain caffeine. So does decaf. Stephen Cherniske — biochemist, author of Caffeine Blues — writes that a 12-ounce cup of decaf can still contain at least 10 mg, and sometimes more. This is not theoretical. A friend told me he had quit coffee and didn’t notice much difference. I asked what he was drinking instead. “Tea.” “What kind?” “Black tea. Green tea.” I was like: “Bro, you don’t even know what a caffeine-free state feels like.” If you want to know what your real state of consciousness feels like without caffeine, you have to go to zero. For me, that has meant organic rooibos tea — no caffeine, still contains polyphenols. I also drink herbal teas like mint or fruit tea, or just mineral water.
no.mind68,477 просмотров • 14 дней назад
Caffeine taken at 7 AM still measurably worsened sleep at 11 PM. Caffeine stays in your system far longer than most people realize. Matthew Walker explains that it has an average half-life of ~5-6 hours & a quarter-life of ~12 hours. That means if you drink coffee at noon, around 25% of that caffeine can still be circulating in your brain at midnight. And being able to fall asleep doesn’t mean caffeine isn’t affecting your sleep. Walker describes people who drink coffee at night and say: “I can still fall asleep.” But when you measure their electrical brain activity, their deep non-REM sleep can drop by around 15–20%. Walker compares that reduction to aging someone by around 20 years overnight. And drinking caffeine early in the day doesn’t necessarily protect your sleep either. In one experiment at the Institute of Pharmacology in Zurich, researchers gave 9 healthy men 200 mg of caffeine at 7:10 AM. By 11 PM, blood caffeine levels had fallen by 82%, meaning about 18% of the caffeine was still in their blood. Then the researchers tested their sleep. Compared with placebo, the men had significantly lower sleep efficiency, less total sleep time and altered EEG activity during sleep. Sixteen hours after drinking caffeine. That’s what makes caffeine deceptive. You drink it in the morning, feel the stimulation wear off, go to bed, fall asleep, and assume it’s gone. But caffeine can still be changing the architecture of your sleep. Michael Pollan describes caffeine as borrowing energy from the future. You get the stimulation now. You pay the interest later through the quantity and quality of your sleep. And then the loop starts again. You wake up less recovered. You feel tired. So you drink caffeine. The caffeine masks the tiredness while interfering with the sleep you need to recover from it. The tiredness caffeine masks is partly the tiredness caffeine caused.
no.mind88,442 просмотров • 20 дней назад
Martin Picard — one of the leading scientists studying mitochondria — doesn't take any mitochondrial supplements. No NAD. No CoQ10. No antioxidant supplements. No Urolithin A. He's skeptical of the hype cycles around all of them. His reasoning: "Mitochondria have dozens of functions." Antioxidants were heavily promoted 10–20 years ago. Then we learned that too much can impair normal adaptation and signaling. Even on Urolithin A, where he says the science is fairly compelling: "I trust the wisdom of my body and my mitochondria more than I trust the pharma company that's trying to make and sell this." Another leading mitochondrial researcher who studies mitochondria for a living and doesn't take supplements himself. Nick Lane doesn't either. A pattern hard to ignore. The deeper these researchers study mitochondria, the less interested they seem in trying to outsmart their biology with a supplement stack.
no.mind224,563 просмотров • 2 месяцев назад
7/ Myth #3: Cancer Is a Genetic Disease. Most think cancer comes from DNA mutations & requires chemo, radiation, or surgery. Wrong. Levin shows cancer isn’t about "broken" cells—it’s an information problem. Restore bioelectric order, & you can stop cancer at its source.
no.mind1,434,226 просмотров • 1 год назад
3/ Big idea #1: Mitochondria, not the genes, determines if a cell becomes cancerous When cells can’t make energy with oxygen, they switch to the ancient fermentation pathway. Cancer thrives by burning glucose & glutamine without oxygen. Uncontrolled cell growth follows.
no.mind1,148,762 просмотров • 1 год назад
10/ What damages mitochondria? - Ultra-proccessed foods, high carb at wrong seasons - Insulin resistance - Chronic inflammation - Lack of exercise & movement - Poor sleep - Chemical toxins, heavy metals, mold - EMFs (Wi-Fi, 5G) - Chronic Stress - Viruses (HPV, Hepatitis) - Artificial Blue Light To name a few.
no.mind1,082,483 просмотров • 1 год назад
4/ Seyfried builds on Otto Warburg’s forgotten theory. Warburg won the 1931 Nobel Prize in Medicine. He observed cancer cells ferment sugar even with oxygen (Warburg Effect) and believed cancer was metabolic, not genetic. Modern science ignored him. Seyfried didn’t.
no.mind1,061,444 просмотров • 1 год назад
Nick Lane — one of the world's leading biochemists on mitochondria and the origin of life — doesn't take supplements. His reasoning: "So if you're thinking about taking supplements or whatever it may be, you've got to think — what are the long-term consequences of doing this? We don't really have any good information on how that's going to work out in the long run. And you don't know what you're missing. So that's why I don't do it personally." Your biology operates as a system. Affect one variable and you affect everything connected to it. Take antioxidants as an example. For decades, health advice pushed them as the fix for aging — on the assumption that free radicals are cellular garbage to be swept away. According to Lane, that assumption is wrong. At normal levels, free radicals act as signals. When mitochondria run into metabolic stress, those signals alter transcription factors in the nucleus — proteins that switch genes on and off. They tell the cell what to do next: build fresh mitochondria, activate its own antioxidant defenses, or trigger apoptosis — programmed cell death — if the damage is beyond repair. Flooding the system with antioxidant supplements mutes that signal. It leaves the cell blind to its own internal state. But there's a second problem — independent of the signaling issue. Researcher Gustavo Barja traced most free radical leakage to one specific subunit inside Complex I — out of more than 40 subunits in that single complex. Free radicals leak directly into the space right next to mitochondrial DNA. There are tens of thousands of complexes per mitochondrion. Hundreds of mitochondria per cell. Roughly 50 trillion cells in the body. Hitting that exact site with enough antioxidant concentration is close to impossible. Antioxidant supplements don't fail only because they mute a signal. They fail because the target is unreachable. You cannot supplement your way out of a systems problem.
no.mind138,167 просмотров • 2 месяцев назад
