A tremor that resembles a bird flapping its wings... is called a wing-beating tremor.❓ Which disease is it classically associated with? A) Parkinson disease B) Wilson disease C) Cerebellar ataxia D) Essential tremor Video Credit:- NEJM Group on YouTube. NEJM Clinician NEJM Groupshow more

A 62 year old man comes to OPD with... a simple complaint. Doctor, my left hand does not stay still. I watch him quietly before examining him. When his left hand rests on the chair, there is a slow, coarse tremor. When he stretches his arms forward, the tremor continues. When he is asked to touch his nose, the tremor markedly increases as the finger approaches the target. This is not a single tremor. This is rest, postural, and intention tremor together. Then comes the old history that changes everything. Eight months ago, he had a right thalamic hemorrhage. There was weakness initially, which slightly improved. The tremor appeared only months later. That delay is important. This is not Parkinson’s disease, because the tremor does not settle with movement. This is not a pure cerebellar tremor, because it is present even at rest. This pattern fits Holmes tremor. Now the localisation becomes clear. The lesion was in the right thalamus. The thalamus is the final relay for two major motor systems. The cerebellothalamic pathway carries coordination signals from the cerebellum. Its disruption explains why the tremor worsens during target-directed movement. The basal ganglia thalamic motor modulation controls stability at rest. Its disruption explains why the tremor is present even when the hand is relaxed. A single thalamic lesion can disturb both systems at once. Because motor control is contralateral, a right thalamic hemorrhage produces symptoms in the left hand. The tremor appears late because this is not just tissue damage. It reflects delayed maladaptive reorganisation of motor networks. The final diagnosis is left-hand Holmes tremor due to a right thalamic hemorrhage. Permission taken for the vdo #Neurotwitter #Medtwitter #Holmesshow more

this moth, Macrocilix maia has taken camouflage to a... different level It has a photo realistic mural on its back, 2 red eyed flies on bird guano, you can even see the light reflecting off the flys' wings A scene associated with potential disease, a risk best avoided by its potential predators. 📹 untamed_pathsshow more

A patient with progressive leg edema, ascites, and a... pansystolic murmur has the neck finding shown in this video. What is this physical sign called? Bonus: Which valvular lesion is classically associated with it?show more

"When you join a group in which you are... attempting to accomplish something that no one individual could accomplish on his/her own, accountability is a must. For any organization or individual to be its best, it cannot hide from accountability."show more

A group calling itself "The Islamic Movement of the... Companions of the Right" appears to claim responsibility for a bombing on a synagogue in Liege, Belgium on Monday. --- My initial impression is that the logo is a near carbon copy of terrorist groups associated with the so-called Iranian-led Islamic Resistance (Hezbollah, Iraqi militias). The statement was dessiminated as early as Monday and the video appears to have emerged earlier today. Furthermore, both the statement and video appear to have first emerged on online networks associated with the Shiite axis of armed groups. I will unpack this further at a later time.show more

Has Biren Singh failed 2 control its homegrown insurgent... groups? Take a look at dis video wherein armed militants with LMG counter a column of security forces. As per a reliable source, dis group is none other than Arambai Tenggol in Imphal near d CM secretariat at 7pm on Nov1.show more

The aircraft that launched the stealth revolution is headed... to its next mission. ✈️ With support from Lockheed Martin and the 512th Airlift Wing, this F-117 Nighthawk was loaded aboard a C-5 Galaxy and transported to the National Air and Space Museum, where its legacy will inspire future generations. AFA and Air & Space Forces Magazine were on the C-5 that carried the Nighthawk from Skunk Works to IAD. The aircraft is currently in the Mary Baker Engen Restoration Hangar, having its wings reinstalled before it goes on public display.show more

To those abroad who are interested in knowing what’s... happening in Denmark; The leader of en extreme left wing party Enhedslisten shared a video from a demonstration in front of Danish parliament yesterday, where “death death to the IDF” is clearly heard chanted by a large group of people. After being confronted with the fact that he shared a video with incitement to murder, the party leader Pelle Dragsted first lied - saying he couldn’t hear the chants - then downplayed the severity, shaming those who called him out for sharing the video. The “slogans” as he called it weren’t important in this context. Israel’s “genocide” is. He then went on to delete the post and repost the same video without sound. It’s the same party that sent money to a Palestinian terror group (DFLP) which took part in the October 7 massacre. The same party which has joined demonstrations in Copenhagen where Hamas merchandise was handed out and protest leaders chanted Intifada Revolution. A party whose members openly praise notorious antisemite Fransesca Albanese and have called for Israel to be disarmed and dissolved.show more

Israel is building tiny robots INSIDE your body. Researchers... at the Technion have developed DNA origami NANO-ROBOTS, programmable microscopic machines (just 100 nanometers wide) made entirely from DNA. These tiny “robots” navigate through the bloodstream, detect specific CANCER CELL markers, and then deploy a targeted TOXIN directly INTO the TUMORS, while completely sparing the HEALTHY cells. In recent trials on aggressive cancers, they’ve shown incredible PRECISION and EFFECTIVENESS. This isn’t science fiction anymore. It’s Israeli innovation turning the body into its own battlefield against disease. There's another nanotech that they’re working on to fix MOTOR NEURONS, which would help those with ALS/Lou Gehrig's disease.show more

"You Dropped a Bomb on Me" (Aug 1982) is... synth funk with that falling bomb whistle and timpani rolls. It reached No. 2 R&B and No. 31 Hot 100. Do you remember this group or the song?show more

Dr. Joel Wallach revealed a medical doctor's average lifespan... is 56 years old. And the average US lifespan is 76 years old. Doctors live 20 years YOUNGER than most likely your parents, your neighbours, and even the guy who never goes to the gym. He asks the interviewer one important question: "Why would anyone listen to a group of people whose average lifespan is 56 years about how to live longer and healthier?" Wallach has a degree in agriculture, a doctorate in veterinary medicine, and has performed over 20,000 autopsies on animals and humans. He says his most important discovery after all this was: Every animal and every human that dies from "natural causes" actually dies of a nutritional deficiency disease. The "natural causes" he's referring to are: • Alzheimer's • Heart failure • Osteoporosis He says in veterinary medicine they had to learn how to actually prevent disease through nutrition because there is no health insurance for animals. A farmer is not paying $78,000 for a hip replacement on a $10,000 bull. So they found real solutions. All the diseases listed above are just nutrient deficiencies. He says if everybody supplemented with the 90 essential nutrients the way he has for 68 years, the medical system would be very unhappy. — Dr. Joel Wallachshow more

sorry, they just did WHAT someone gave a machine... one disease name, the leading cause of blindness in the developed world with 1.5 million americans already in its path, and it came back pointing at a drug that has sat in pharmacies for years under a different label: 551 papers read in 30 minutes against the 294 hours a human would have needed, and the loop that did it is public on GitHub most agent setups answer one question at a time, so the ceiling on the work is the quality of the question you happened to think of this one was handed a single question and wrote the second one itself. turns out that follow-up is where the real find was: a target called ABCA1, upregulated threefold, in an experiment no human ordered i read the whole paper looking for the trick, and the trick is structural. that is the second question, and it is the gap between an assistant and a factory: - hand the loop a field rather than a task: it was given a disease, and choosing the mechanism was part of its job - make it rank before it spends: 151 papers in, ten candidate mechanisms out, scored against each other before anything touched a bench - split reading from judging, so the agent that forms the theory is a different agent from the one grading it - close every cycle on physical reality: the verdict was an experiment, and another model's opinion was never allowed to stand in for one - feed each result back as the next question rather than a log line, which is the step almost nobody builds - search what already passed inspection first: the winner was an approved compound with a safety file already on record - write down what the round learned before opening the next one, so round two starts where round one stopped my read, and i think it is the uncomfortable one: reading was the entire bottleneck in that field, and everybody spent the decade optimising the writing. people ran every physical experiment here, the analysis agent needs a domain expert writing its prompts, and the authors decline to call this the leap it resembles. the thinking got replaced, and the hands did not so the question i cannot answer for my own setup: which step of your loop still stops dead until you sit down and type something bookmark this one. the four parts that turn one model into a line that runs like this, the queue, the rooms, the write permissions and the gate, are built file by file in the piece below ↓show more

“Met Police can go to hell.” Palestine Action and... its supporters have sent a clear message: they have nothing but contempt for Metropolitan Police frontline officers. When a group of extremists takes to the streets to defend a soon-to-be proscribed terrorist group and protest against those who risk their lives to keep our streets safe, it is a frighteningly clear indication that something has gone very wrong in this country. The authorities have a lot to answer for. This ban on Palestine Action — as called for by CAA and others — is a good start, but it should have happened a long time ago, as should bans on these kinds of protests. This must be the start of a clampdown on lawlessness and extremism if it is to be of any consequence.show more

How the 🆅🅴🅽🆃🆁🅸🅲🅻🅴 contracts.. . . . 💗Another great... thing I picked up from Cardiothoracic surgery was understanding how the ventricles contract. The ventricle Is such a complex structure that we are learning more and more about. One thing that has helped us understand this complex structure is strain imaging and 3D echocardiography. We have learned that the ventricle contracts in 4 ways: contraction (radial) motion but it also has a twisting (torsional and circumferential) and shortening (longitudinal) motion. . . . 👐🏽The surgeon I always work with often described the hearts motion as “wringing of a towel.” This can be seen in the video above. The understanding of the multiple different motions of the heart has allowed us to better understand intrinsic myocardial disease and pick up disease earlier in its process allowing us to add disease modifying agents to slow and sometimes reverse the negative remodeling of the heart. . . . 💓So next time you think of your heart pumping don’t think of it in one motion (squeeze) but rather a Towel being wrung of water. The heart is such an amazing organ and we are just now really beginning to understand it’s truly complex physiology! . . . Have a great day! . . . . #Medicalschool #medschool #cardiologia #doctors #cardiotwitter #meded #EKG #Medstudent #cardiology #internalmedicine #patient #hospital #radiology #physiology #paschool #foamed #echo #physicalexam #anatomy #scrubs #surgery #pastudent #nursingstudent #nursing #PA #DO #Echocardiogram #MD #USMLEshow more