Announcing Neo-1: the world’s most advanced atomistic foundation model,... unifying structure prediction and all-atom de novo generation for the first time - to decode and design the structure of life 🧵(1/10)show more

ESMFold2 and the ESM-C family, now available for use!... We’ve partnered with biohub (the ESM team’s new home), to provide day 1 access to their newly open-sourced series of models. The family of models show best-in-class results for structure prediction, de novo design, and protein-language model tasks.show more

Announcing AlphaFold 3: our state-of-the-art AI model for predicting... the structure and interactions of all life’s molecules. 🧬 Here’s how we built it with Isomorphic Labs and what it means for biology. 🧵show more

🔥Spatial intelligence requires world generation, and now we have... the first comprehensive evaluation benchmark📏 for it! Introducing WorldScore: Unifying evaluation for 3D, 4D, and video models on world generation! 🧵1/7 Web: arxiv:show more

The 10 biggest medical research papers from this week... (🧵) 1. A high resolution structure of the dopamine transporter - key to Parkinson's, schizophrenia, and addiction Here's what it looks like bound to cocaine, one of its ligands (in orange) (Study:show more

Diffusion models are an amazing tool for cofolding, they... allow us to predict a protein and the molecule bound to it at once. But they are not exactly fast and require a lot of denoising steps to get accurate predictions. So we distilled ours. Meet DeCAF-Pearl: the first flow map model for all-atom cofolding. Instead of inching along the denoising trajectory, a flow map learns to jump across it. DeCAF-Pearl runs structure generation ~5x faster than Pearl, our SOTA model, while still maintaining the performance of the teacher model. That speed up allows us to run larger experiments and generate more synthetic data to improve our models. Getting there meant reparameterizing into noise-level space to stabilize gradients, committing to clean-structure prediction to keep the rigid-alignment loss biomolecules needed, and building DeCAF-Search, one steering algorithm for every compute budget. For more technical details, read out blog post: And the paper:show more

Real-time generation isn’t about predicting the next pixel, it... requires understanding the structure and context of a 3D world. That’s the shift. Read more about our real-time game-native diffusion model on our blog. Moonlake's Reverie v0.1.0show more

1) What do Bitcoiners and 🇿🇦 South African Caves... have in common? A 🧵thread on the world’s first example of proof of work and the birth of money:show more

Today we’re announcing Petal: the world’s first petabit-class transoceanic... subsea cable and the first to deploy multi-core fiber at scale. Spanning 7,000 km (4,000+ mi) between France and the United States, Petal will deliver 1 Petabit per second (1 Pbps / 1,000 Tbps), doubling the capacity of today’s most advanced transatlantic systems. Petal is set to enter service in 2029, setting a new standard for high capacity, high density SDM subsea cable designs. Read the full technical breakdown on our engineering blog:show more

-New Character Model Showcase- 🧵 Part 1: Poo Out... of the chosen four, Poo is the one I took the most creative liberties with the design, so he has a few distinct details.show more

Different observers can disagree about space and time without... disagreeing about the laws of physics. In Minkowski spacetime, observers moving relative to one another use different space and time axes, connected by the Lorentz transformation. What remains unchanged is the spacetime interval and the structure of the light cone. Space and time coordinates depend on the observer, but the speed of light and the causal structure of spacetime do not.show more

As announced in partnership with NVIDIA at CES, we’re... excited to introduce Stable Point Aware 3D (SPAR3D), setting a new standard in 3D generation. Ideal for running on NVIDIA RTX AI PCs, SPAR3D enables real-time editing and complete structure generation of 3D objects from a single image in under a second. You can download the weights on Hugging Face and code on GitHub, or access the model through the Stability AI API. Learn more here: (1/3)show more

These are the most iconic moments on TV. A... thread 🧵 1. This might just be one of the most brutal TV fails of all timeshow more

The moment we've all been waiting for! 🤖🔥 Introducing... you ChainGPT, our first #AI incubation project and a game-changing solution for navigating the complex world of #crypto and #blockchain technology. Their advanced AI model offers a wide range of use cases:👇 (1/2)show more

Caleb Williams hates structure and getting the ball out... of his hand on time.show more

The Quick Reaction Force is assigned to the #BorelFire... tonight to provide structure protection for the communities of Bodfish and Havilah.show more

1 billion cells. One atlas. Today, Illumina introduces the... Billion Cell Atlas, creating the most comprehensive map of human disease biology — and unlocking unparalleled speed and scale in AI for drug discovery. The Atlas will help researchers, including founding participants AstraZeneca, Merck, and Eli Lilly and Company study the effect of switching on and off all 20,000 genes in cells linked to diseases that have been historically difficult to decode. Learn how the Atlas will elucidate the biological pathways behind some of the world’s most devastating diseases: #JPM2026show more

Seedance 2.5 is live on Hedra API and Create.... We spent the night building prompt guides and loading the Hedra Agent with encyclopedic knowledge of how to get the most out of the model. Share this post and comment Hedra below for credits to test the world's most advanced model.show more

The world’s largest sculpture of the markhor, Pakistan’s national... animal, has been unveiled in the country’s Kaghan Valley. The 105-foot-high and 38-foot-wide structure took five years to complete.show more