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1/ “When you have persistent pathogens & chronic inflammation associated with that, you have a lot of reactive oxygen species. The mitochondria are trying to create energy in a hostile environment…the more that you do, the harder it is to [function].” -Dr. Putrino of CoRE at Mount Sinai
54,251 views • 1 year ago •via X (Twitter)
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2/ Dr. Putrino, Nash Family Director of CoRE, discussed mitochondrial dysfunction associated with IACCs with Dr. Proal (CoRE Scientific Director) and Dr. Baxter (CoRE Science Comms Director) as a part of the new clinic’s ongoing education efforts. Full replay here:

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@CoRESinai It's good to see this description. My muscles/nerves/tendons were damaged by FQ's (cipro). Whenever I try to regain muscle (a damaging process) I get several weeks of increased MCAS/histamine issues/insomnia/weakness as a result. Damned if I do and don't describes this dynamic.

@CoRESinai Many people with ME take various supplements to try to address ROS. Which ones do you think are most effective? Also re persistent pathogens, which to test for? There's no help here, an NHMRC Inquiry is going to take 3 years, most GPs are not educated on these issues.

@CoRESinai what are the drugs he speaks of that help with mitochondrial dysfunction?

@CoRESinai But supporting the mitochondrial with drugs is a bandage- is it not? What about getting to the real cause? Thanks!

@loscharlos @CoRESinai Thank you. Thank you. Thank you. #Lyme

@CoRESinai Useless. No evidence of persistent pathogens driving dysautonomia in long covid.

@CoRESinai Dare I add that the National Institute of Health has a dietary supplements page for Primary Mitochondrial Disorders ( your experience is of course more insightful, but just in case… )

@CoRESinai Can we try and do better with drive by posts that throw an idea out there with no follow up. It’s like reading a story half written. While I appreciate you all, it’s frustrating.
