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36% LESS artery plaque. That's what researchers reported after one year using 10,800 FU/day of nattokinase in over 1,000 participants. Too good to be true? I break down the entire study, the strengths, the weaknesses, and whether this changes how we should look at nattokinase. 👇

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291,831 просмотров • 1 месяц назад •via X (Twitter)

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Joe Rogan recently talked about a study involving 1,062 participants who took nattokinase for a full year. According to the reported ultrasound findings, arterial plaque was reduced by roughly 36%. The enzyme is said to help prevent new blockages while also supporting the reduction of existing plaque buildup. Here’s a closer look at the data and dosage protocol: (1/12)
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Joe Rogan recently talked about a study involving 1,062 participants who took nattokinase for a full year. According to the reported ultrasound findings, arterial plaque was reduced by roughly 36%. The enzyme is said to help prevent new blockages while also supporting the reduction of existing plaque buildup. Here’s a closer look at the data and dosage protocol: (1/12)

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David Sinclair just revealed one of the biggest studies on nattokinase. A comprehensive Chinese study of 1,067 people found that nattokinase reversed cardiovascular disease by removing up to 95% of arterial plaque in one year. This supplement is an enzyme from fermented soybeans and costs almost nothing. Sinclair has been taking it daily for a couple of years. He measures his carotid artery with ultrasound and says there's no plaque buildup at all. Peter Diamandis takes it too. He believes you need at least 6,000 fibrinolytic units per day to reap the benefits. For context: • Statins cost hundreds per month and come with side effects. • Surgical interventions can cost thousands of dollars Nattokinase costs a fraction of both. Sinclair's caveat: "Do this with the knowledge of your physician." But the data exists. A study of over 1,000 people and up to 95% plaque removal in just 12 months. And the man whose lab is reversing aging takes it every day. — David Sinclair (David Sinclair) on Peter Diamandis' (Peter H. Diamandis, MD) Moonshots podcast PS. David Sinclair is speaking at SynBioBeta on May 6th this year, discussing the science of slowing and reversing aging. If longevity is the world you're in, the investors, partners, and scientists shaping this space will be in the room. Grab your ticket in the comments below.
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David Sinclair just revealed one of the biggest studies on nattokinase. A comprehensive Chinese study of 1,067 people found that nattokinase reversed cardiovascular disease by removing up to 95% of arterial plaque in one year. This supplement is an enzyme from fermented soybeans and costs almost nothing. Sinclair has been taking it daily for a couple of years. He measures his carotid artery with ultrasound and says there's no plaque buildup at all. Peter Diamandis takes it too. He believes you need at least 6,000 fibrinolytic units per day to reap the benefits. For context: • Statins cost hundreds per month and come with side effects. • Surgical interventions can cost thousands of dollars Nattokinase costs a fraction of both. Sinclair's caveat: "Do this with the knowledge of your physician." But the data exists. A study of over 1,000 people and up to 95% plaque removal in just 12 months. And the man whose lab is reversing aging takes it every day. — David Sinclair (David Sinclair) on Peter Diamandis' (Peter H. Diamandis, MD) Moonshots podcast PS. David Sinclair is speaking at SynBioBeta on May 6th this year, discussing the science of slowing and reversing aging. If longevity is the world you're in, the investors, partners, and scientists shaping this space will be in the room. Grab your ticket in the comments below.

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David Sinclair says he’s been reversing plaque in his arteries with nattokinase. On Peter Diamandis’ podcast, Sinclair shared that he’s been taking it for years and mentioned a Chinese study with 1,086 people that showed up to 95% plaque reduction in one year at sufficient doses (at least 12 fibrinolytic units daily). He also checks his own carotid arteries with ultrasound and says there’s no buildup. Nattokinase is an enzyme from fermented soybeans that breaks down fibrin. Some human studies show it can help reduce arterial plaque and improve blood flow, but results vary. Larger, high-quality trials are still limited, so it’s considered promising but not definitive. Cardiovascular disease is still the #1 killer. If there are accessible tools that support artery health beyond statins and lifestyle, it’s worth paying attention. Have you heard about nattokinase or tried anything similar for heart health?
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David Sinclair says he’s been reversing plaque in his arteries with nattokinase. On Peter Diamandis’ podcast, Sinclair shared that he’s been taking it for years and mentioned a Chinese study with 1,086 people that showed up to 95% plaque reduction in one year at sufficient doses (at least 12 fibrinolytic units daily). He also checks his own carotid arteries with ultrasound and says there’s no buildup. Nattokinase is an enzyme from fermented soybeans that breaks down fibrin. Some human studies show it can help reduce arterial plaque and improve blood flow, but results vary. Larger, high-quality trials are still limited, so it’s considered promising but not definitive. Cardiovascular disease is still the #1 killer. If there are accessible tools that support artery health beyond statins and lifestyle, it’s worth paying attention. Have you heard about nattokinase or tried anything similar for heart health?

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Dr. Ovadia says nattokinase is something he routinely recommends as part of his protocol for patients. It a fibrinolytic agent, meaning it helps the body break down blood clots as they start to form. He points to a trial showing reduced arterial plaque in patients taking it, though that study measured carotid (neck) plaque rather than coronary plaque, which he flags as a caveat. As mentioned below, the trial tested 3,600 units daily (not statistically significant) versus 10,800 units daily (significant plaque reduction), so he typically suggests around 10,000 units a day. He cautions that many supplements are dosed too low or poorly sourced, and that anyone on blood-thinning medication should talk to their doctor first. (h/t Ken D Berry MD & DoctorTro)
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Dr. Ovadia says nattokinase is something he routinely recommends as part of his protocol for patients. It a fibrinolytic agent, meaning it helps the body break down blood clots as they start to form. He points to a trial showing reduced arterial plaque in patients taking it, though that study measured carotid (neck) plaque rather than coronary plaque, which he flags as a caveat. As mentioned below, the trial tested 3,600 units daily (not statistically significant) versus 10,800 units daily (significant plaque reduction), so he typically suggests around 10,000 units a day. He cautions that many supplements are dosed too low or poorly sourced, and that anyone on blood-thinning medication should talk to their doctor first. (h/t Ken D Berry MD & DoctorTro)

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