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A 3D map of mRNA transcripts in a zebrafish embryo. This video was not made using a microscope. Researchers tag nucleotides with barcodes, which then "link" together in the tissue. Sequencing those links can then be used to computationally infer the 3D positions of genes.

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Niko McCarty.

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24,508 просмотров • 1 год назад •via X (Twitter)

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A sneak peak of a complex and technically challenging experiment that my lab developed: Super proud of PhD candidate Hannah Johnson for showcasing our Whole-gut spatial genomic analysis in #zebrafish. This video illustrates one landmark in the protocol after multiple rounds of sequential #HCR and 3D imaging in zebrafish larvae to reveal spatial expression of numerous mRNAs in the same specimen. Data from these imaging data sets are then computationally analyzed for spatial cell groups, spatially variable genes, and differentially expressed genes along 3D. We are leveraging this systems-level SGA to uncover unappreciated mechanistic insight at the cell and tissue levels into #ENS construction. Stay tuned for our work that exploits this pipeline within various mutant and perturbation conditions. Reach out if you are interested in trying this! #fruitypebbles
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A sneak peak of a complex and technically challenging experiment that my lab developed: Super proud of PhD candidate Hannah Johnson for showcasing our Whole-gut spatial genomic analysis in #zebrafish. This video illustrates one landmark in the protocol after multiple rounds of sequential #HCR and 3D imaging in zebrafish larvae to reveal spatial expression of numerous mRNAs in the same specimen. Data from these imaging data sets are then computationally analyzed for spatial cell groups, spatially variable genes, and differentially expressed genes along 3D. We are leveraging this systems-level SGA to uncover unappreciated mechanistic insight at the cell and tissue levels into #ENS construction. Stay tuned for our work that exploits this pipeline within various mutant and perturbation conditions. Reach out if you are interested in trying this! #fruitypebbles

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✨ Made a new mini feature on Photo AI: [ Grab from 3d model ] So the problem is we're at that stage in time (typical for AI) where image-to-3d models are not good enough but are fun to play with, but we know they'll be good enough in 1-2 years With [ Make 3d model ] you already can turn any Photo AI pic into a 3d model but it still looks hyper clunky and deformed, but it works! One cool idea I had to make that more useful and made now: Let people make a 3d model then change the view of the it with the 3d viewer, then press [ o ] and it grabs a frame of the 3d That image you can then [ Remix ] (img2img), and it becomes a real photo again and that in turn you can then turn into a video again with [ Make video ] So that essentially gives you a fully freeform camera position control to take photos with One thing I need to fix is the background/skybox, I kinda need to take the original photo and remove the person and just get the background for the 3d model viewer, in this case it should be white, but it's a start!

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From what I heard from one of the staff they used 3D models for the LOs then hand drew more than 15k frames using the 3D models as a base. This apparently took months to complete. Insane dedication by the Bibury Staff
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From what I heard from one of the staff they used 3D models for the LOs then hand drew more than 15k frames using the 3D models as a base. This apparently took months to complete. Insane dedication by the Bibury Staff

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The lines between code & content are blurring. I made this 3d city block animation in claude 3.7. Then I used runway gen-3's video-to-video to style it like a lego city at night. At the rate things are going, this'll be a shader running in real-time.

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CSM 3D AI: New image-to-3D AI program AI is reshaping the future of 3D design. This amazing tool transforms still images into 3D models, and the best part? You can animate them effortlessly using AI. Link in comment!
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CSM 3D AI: New image-to-3D AI program AI is reshaping the future of 3D design. This amazing tool transforms still images into 3D models, and the best part? You can animate them effortlessly using AI. Link in comment!

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i work with a lot of designers, who create amazing scenes. I want to animate them in after effects in 3D, however once you apply distance, the layers change size. So i made this script which you can use to create 3D space yet keep the intended scale correct

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In the interests of balance, was this not a penalty either then? #itfc
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In the interests of balance, was this not a penalty either then? #itfc

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Ok, So i was going to make starship in desmos 3d because I thought it would be cool but then I found someone who made a fully working starship landing simulator in desmos what the fuck.
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