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$ABCL CEO Carl Hansen explains the net negative overall value creation in biotech and how AbCellera plans to beat it: “I really think it can be beat because there’s a lot of mistakes that get made in where you allocate capital.” “If you’re a biotech and you start a...

31,665 次观看 • 1 个月前 •via X (Twitter)

14 条评论

Dr.Karp4POTUS 的头像
Dr.Karp4POTUS1 个月前

Carl confirms that the value of the company is the platform. Faster and higher quality drugs to market.

Jack Prescott 的头像
Jack Prescott1 个月前

And the decision making by management on what to advance:

MyLongTermPortfolio 的头像
MyLongTermPortfolio1 个月前

Jack if you don’t mind me asking, do you work for AbCellera? You posted pics of their GMP lab so I am curious to know. I enjoy all your deep dives about the company and the science behind it.

Jack Prescott 的头像
Jack Prescott1 个月前

🤣🤣 no. I got those off of LinkedIn

MyLongTermPortfolio 的头像
MyLongTermPortfolio1 个月前

lol make sense! So your background education is in science or just love enjoying searching for companies as a hobby?

Jack Prescott 的头像
Jack Prescott1 个月前

Finance. I just love AbCellera and as a result became really interested in what they do and how it all works and as I learned more I became more interested

MyLongTermPortfolio 的头像
MyLongTermPortfolio1 个月前

Impressive! I came from science background and work in similar industry and do enjoy your deep dives on science related topic. I definitely believe in AbCellera vision as long term investor!! I am sure patient long term investors will be rewarded handsomely!

Jack Prescott 的头像
Jack Prescott1 个月前

Thanks! It sure is fun learning about this company. Long and strong 💪

Frank Slaughter 的头像
Frank Slaughter1 个月前

We know he is striving to create a big company. He mentions that there were acquisitions of 10B, 20B a large company spent and it still busted ... so this gives you an idea of HOW BIG of a fish is going to become. Carl has the vision to see the path and the balls to walk it

Owlosophy 的头像
Owlosophy1 个月前

Thank you for the great insight. It clearly shows that Abcellera is moving past the startup stage and is well on its way to becoming a big pharma. This company does not depend on a single drug, thanks to its diversified pipeline.

ALL IN 2028 LMND CALLS 的头像
ALL IN 2028 LMND CALLS1 个月前

im so used to seeing him edited as a giga chad, this feels uncanny

Jack Prescott 的头像
Jack Prescott1 个月前

🤣🤣

John Spanos 的头像
John Spanos1 个月前

@tyler_bosserman Buying more on Monday

CompoundingKS 的头像
CompoundingKS1 个月前

I revisit this video when the price action of stock affects me. Very good discussion and insights by the founder and how fond he is for the company.

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.Naval: You define wealth in a beautiful way. You talk about wealth as a set of physical transformations that we can affect. So as a society it becomes very clear that knowledge leads directly to wealth creation for everybody. A given individual can obviously affect physical transformations proportional to the resources available to them—but much more proportional to the knowledge available to them. Knowledge is a huge force multiplier. You then define resources as the thing that you combine with knowledge to create wealth. New knowledge allows you to use new things as resources and discard old things that maybe we’re running out of. There are lots of examples of how we’ve done that in the past. For example, in energy we’ve gone from wood to coal to oil to nuclear. But then people say, “Now we’re out of ideas. Now we’re caught up. Now we’re done. There aren’t going to be new ideas, and now we have to freeze the frame and conserve what we have.” The counter to that is, “No, we’ll create new knowledge and have new resources. Don’t worry about the old ones.” Well they say, “If you’re going to have new resources, if you can’t think of them now, it’s not real.” This now gets into the realm of people demanding that if you’re going to claim that new knowledge will be created, you have to name that knowledge now. Otherwise it’s not real. But that seems like a Catch-22. David Deutsch: It does, and it’s a bad argument. I don’t want to claim that the knowledge will be created. We’re fallible; we may not create it. We may destroy ourselves. We may miss the solution that’s right under our nose, so that when the snailiens come from another galaxy and look at us, they’ll say, “How can it possibly be that they failed to do so-and-so when it was right in front of them?” That could happen. I can’t prove or argue that it won’t happen. What I always argue, though, is that we have what it takes. We have everything that it takes to achieve that. If we don’t, it’ll be because of bad choices we have made, not because of constraints imposed on us by the planet or the solar system. Naval: It will be by anti-rational memes that restrict the creation of knowledge and the growth of knowledge. David Deutsch: Maybe. Or maybe it’ll be by well-intentioned errors, which nobody could see why they were errors. Again, it doesn’t take malevolence to make mistakes. Mistakes are the normal condition of humans. All we can do is try to find them. Maybe not destroying the means of correcting errors is the heart of morality; because if there is no way of correcting errors, then sooner or later one of those will get us. Naval: Don’t destroy the means of error correction is the base of morality. I love that. I think about places like North Korea where you can’t have elections and a revolution is very difficult because the gang in charge is armed to the teeth and they’ve destroyed the means of political error correction for a long time. That is a case where humanity is trapped in a local minimum, and it’s very hard to climb out of that hole. If too much of the world falls into that mindset, then we as a species may just stagnate because we’ve lost our biggest advantage. We’ve lost our biggest discovery, which was the ability to make new discoveries.

Deutsch Explains

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Marc Andreessen on the 3 things he looks for when investing in a startup The first thing Marc Andreesen looks for is a big market: “Is there a big existing market that you think you can go after and displace incumbents? Or do you believe there will be a new market that will be big?” The second thing he looks for is a 10x better product: “Is there a fundamental technology or economic change that justifies a new company? And the way I always think about that is: Is there a 10x change happening in the technology landscape? Is something 10x faster, 10x cheaper, or 10x better? If it’s not 10x, we as both VCs and entrepreneurs have to ask ourselves if it’s really worth doing because it’s really hard to start new companies . . . Existing companies are usually pretty good at what they do. So for a new company to exist, it has to bring a product to market that’s so much better than what exists that it punches through the status quo.” The third is the team: “Is the team outstanding? . . . You want to have a founding team of complementary skillsets. You want to have at least one super strong technologist — quite possibly more than one. Some of the best startups are actually more than one founding technologist. And then it often helps to have someone who is a marketing or salesperson who has a really good understanding of business.” Marc believes that you need all three of these, but if you’re going to compromise on one of those as an investor, it should be the product: “A great market is a lot easier to make up for with iterative product execution. The problem with a poor or small market is that even if you do a good job on the product, there just aren’t that many customers so it’s hard to ever get big and people get demoralized . . . And then we evaluate the team of a startup by its ability to get into a big market with a good product.”

Startup Archive

17,333 次观看 • 7 个月前

Paul ‘Triple H’ Levesque was asked about a comment Damian Priest made recently about the same talent being in the top spots, and answers Jamie Iovine’s question on how he feels about the current generation of stars going forward and the “changing of the guard” right now in WWE — “Look, I get that. If you’re the guy that wants to take the spot, it’s frustrating when there’s guys above you that have the spot. We’re in a period of time where there’s a lot of top performers in top spots that over time have earned those spots and are selling tickets and are incredibly popular. So you really have to do something. The narrative of ‘It’s my turn. I’ve been here for a while’. There’s no turns. That’s not how it works. You earn the spot. Believe me. If somebody is getting over more than somebody else, we move that person into the spot and move the other person down. But it’s not just that, it’s not just they’re getting the loud crowd reaction. Are they going to be good in the spot? Are they going to hold up their end of the bargain? Are they going to screw up if we give it to them? Are they going to make a mistake that we regret? — There’s all those things factored in. And I love the fact that sometimes, talent are like ‘Well, it’s frustrating.’ Great, that means work harder. Get yourself there. Figure it out. Figure out the way. Figure how it gets done. I’ve seen a million talent succeed because of what they do. Not because storyline or creative. ‘They gave them the spot’. 99% of the time in this business, the person gets over then gets the push. That’s how it works. That’s how it’s supposed to work. You go do you then we follow it, because otherwise, most of the time, they will choke on it if it’s not what the fans believe in. Big believer in if you want the spot, go take it. Whenever anybody says ‘I don’t know why I’m not in that spot’…well I don’t know, are you more over than Cody? Roman? Punk? Liv? IYO? The people that are in that spot get there. Make those crowd reactions. Whatever you need to make it happen, that’s what we’re all here to do. I love that mentality because I think it makes people work harder, and if they’re not willing to work to get the spot then you shouldn’t have it anyway.” — via #SummerSlam Post-Show

PW Chronicle

93,045 次观看 • 1 个月前

Liam Coen says analytics should inform decisions, never make them “We leverage analytics. Absolutely. We leverage it for the data and the information to make a decision, not to make the decision. That’s not how it goes. Ever.” “You have the data, AI, analytics, it is unreal. What are the true decisions that lie in the moment, in the now? What are the facts that you need to know? That’s great to leverage.” “We have game management. We have an analytics department to gather that information. But we are not making decisions solely based on those numbers. Ultimately, it has to come from the gut and from yourself.” “Is this the best decision for the Jacksonville Jaguars right now? Because that’s all you can live in. You’re living in every single play.” “I’m going to lean aggressive offensively, especially in year one when you’re trying to instill confidence. You’re trying to instill a mindset of, ‘Yeah, we are good.’ I believe we can go get fourth-and-two. We can.” “We talk about momentum a lot as a team. You can feel that. You can feel momentum. You know when you got it and you know when you don’t. I feed off that as a coach and I feed off the player’s energy on the grass and when they have confidence and momentum I want to roll with it, I want to keep it.” “When you have it you wanna stomp on it, you want to make them feel it.. That’s where the aggression comes in, you want to hold onto that and put your foot on the pedal. And as you grow as a coach there are times where you might be like, ‘Alright, may need to kick here. It’s going to be one of those kind of games.’” “So you have to be prepared, know your gut, go with your gut, feel this, all that’s going on around you, and make the best educated decision.”

Josh Chambers

10,496 次观看 • 1 个月前

🛑 Burkina Faso 🇧🇫 - Captain with school boys and girls! The young Captain was having a conversation with the pupils, and here is what he saying, “I was telling you a while ago, in school they were telling us that we couldn’t do it here. They lied to us. We grow wheat here, and it works well, and we will develop it. Some people have started, this year, I was able to see people who did it, as part of the presidential initiative, and I was told that in the past, some were able to do it and they produced it well. Currently, we are sowing wheat in some farmlands as part do the presidential initiative. What you eat must be produced here. So, this is why I say that we will teach you many things, and we will review the curricula they teach you. For those who drink coffee, they told us that your coffee, chocolate, it is only in the countries with abundant rainfalls, that here is only savanna, desert, it does not rain, we cannot farm. Again, they lied to us. It’s not true! Coffee grows well here, cocoa grows well too. There are people here who have the farms here, even in Ouagadougou here, there are people who have cocoa trees in their yards. This means that, chocolate that children envy those from well to do familes can be manufactured here in Burkina and all the children can eat chocolate in Burkina. We found out it is possible. As for milk, why do we have to import it? We can do it. I just want to tell you that there are many things that they never told us the truth about. You guys are lucky, we are now teaching you, and we promise you that we will do all we can so that you can eat your fill. As we say, you will eat well in the morning before you go to school, you will go to school for free, you will eat lunch, you will have fun, and in the afternoon, when you return home, you will have fun in the neighborhood, then in the evening, you will learn and review your homework and sleep. This is the dream we have. As long as the children in Burkina are not in these conditions, our fight will not stop. Ok? (Claps). So, we know these are your aspirations and it is right and legal. Any parent is fighting for this. Even those who do not have children fight in the hope of having children and to take care of them, so that they can live in better conditions, and be better than them. This is the fight of everyone, this is the fight of every generation. We are lucky God gave us everything. Do you know that everywhere in Burkina we can farm? Everywhere! In the Sahel where they tell you it is the desert, it is only sand, we can farm. As for us, we have been lied to so much, it is the brainwashing of the colonizer. He did that so that we may not think 💭. But we finally found out that everything was a lie ( damn lie, emphasis is mine). If God left many lakes in that desert, He knows why. We can farm everything in Burkina, we can do everything, the land is fertile. And there are so many natural things in Burkina that we never planted but they were here, isn’t it ? Have you ever learned how to plant a shea tree in Burkina? You were born and found them already here right? It is there in the wild in nature. You know it is a gift from God. There are many things in the shea fruit. You have the shea butter, that is oil; do you know that there is chocolate in it? There are seven derivatives in the shea fruit. You also have the Parkia biglobosa (also known as the African locust bean) which is a natural fruit. We have many things, it is not only the minerals in the soil. Even with the soil, we were told that it’s ferralitic soil, that it is not fertile, everything is a lie. You see that today there is so much gold in Burkina. But it is just poorly managed. Our mission is to well manage these resources, and to take good care of you, so that you can be in your basic rights, to lead a good life, to go to school, and that we may protect you. And also that you may fulfill your duties, because your duties are very important, aren’t they?…

Sy Marcus Herve Traore

95,027 次观看 • 2 年前

Whitney Webb "It sucks to find out that the mob runs the world... [so] do you want to say, screw you guys, we're going to... get off your... slave plantation?... [because] we can't really keep losing money and rights without being so deep in a hole that we can't... climb out" This clip of Webb (Whitney Webb), a contributing editor of Unlimited Hangout and author of One Nation Under Blackmail, is taken from an interview with Peter McCormack (The Peter McCormack Show) posted to YouTube on September 4, 2025. -----------------Partial transcription of clip-------------- "It's not just about burning it down, it's about putting something better in its place. Of course. And so I think the solutions there, you know, some people are like, oh, Whitney, your work is so demoralizing. Well, I'm like, yeah, it sucks to find out that the mob runs the world, you know, but the question is, or do you just want to let them keep running it because it bums you out, or do you want to say, screw you guys, we're going to build something else and get off your, you know, slave plantation? "And I am in the group of, I would like to build something else. I have three kids. I do not want them living in a world run by the mob. So what are you going to do about it? I mean, it starts locally, it starts with your community, because that's where we can actually affect change. Voting for left or right, blue or red. I mean, it's just this ping pong thing where nothing fundamental is changing. "And so to affect that change, we have to do it ourselves. And you think this would be a core American value? Individualism, individual responsibility. But a lot of people just don't care. And so, you know, that sucks. But I think those of us that do care need, to take steps to be as independent from the system as possible. Because every so often, this predator class, they do wealth transfers or they orchestrate and manufacture events and they make a big grab, not just for our money, but for our rights. And we're at the point where we can't really keep losing money and rights without being so deep in a hole that we can't climb ourself out. Can't climb out. "So what, what should we do before that happens? There is an important window of time to do something about it in our local community and for our families and our friends and our neighbors. And we have to do something because if we don't and that thing happens. Oh, well, I watched all these podcasts and learned about how corrupt everything is. But, you know, and I think they spend a lot of time trying to keep us distracted on all sorts of things and sucked into things that don't matter. So that we just don't give them the finger, basically. And that's what we really need to do."

Sense Receptor

46,951 次观看 • 1 年前

jihoon knowing all the tiny details that women go through when preparing ourselves in going to concerts 🥹 he even knows that we get frustrated bc we dont look as perfect inside the venue compared to when we leave our houses and assured us that the thought of wanting to look pretty for him in itself already makes us beautiful 😭 HOW CAN U NOT LOVE THIS PERSON 🐶 i know that when it rains, your curled hair falls out and everything. i know that your makeup gets messed up and all that. i take all of that into consideration when i look at you, so please don’t worry about it too much. i just don’t pay that much attention to things like that, so don’t worry about it 🐶 isn’t it actually better that i know these things? if i didn’t know, you might think i would find it strange. but i know all of that. i know i know. so don’t worry about things like that 🐶 people with curly hair straighten their hair before coming, but then suddenly it starts getting curly again because of the humidity, and the volume in their hair completely dies down 🐶 i also know that you can leave home thinking “this is the prettiest i habe looked” and then when you arrive at the venue, you look so different from how you did at home, and then it can make you upset because the singer you like is going to see you like this. i know that. 🐶 no my hair gets flat too, and my makeup gets messed up too. when it rains and it gets humid, im like that too so what. ah you don’t have to be embarrassed. you don’t have to be embarrassed because i wont pay attention to it. you don’t have to be embarrassed. 🐶 just come comfortably, and dress up however you want. just think “i’m the prettiest today”, “i’m the coolest”. dress up looking your best and come. come and have fun. 🐶 isn’t everyone like that? when people are in front of someone they like, they want to look good right? they want to show their best selves. 🐶 but whenever it’s an important day, you get sick, or a pimple suddenly comes up on your face. and on days that aren’t important, your skin looks amazing, or you somehow keep losing weight. that’s just how life is for people. it’s not just me. you all probably experience that too. 🐶 because you want to meet us so badly, and because all your attention is focused on us, you might come with a pimple on your face. things might not go the way you want them to. i know all that. i’m a person just like you. i know what it’s like when something happens on an important day. just think of it as me not seeing those things. so come comfortably. 🐶 yeah i know you want to look pretty. and because i know how much you want to look pretty, you look pretty to me. that feeling itself is beautiful, you know? i’m grateful. it feels like you’re being considerate of me. 🐶 when you go to meet someone, getting dressed up instead of just going out carelessly is a consideration for the person you’re meeting. of course it’s also for yourself. of course you can’t help but look pretty. 🐶 whether your makeup gets messed up, your hair curls back up, or whatever happens, its the actions themselves, each and every one of them, are all good you guys. 💬 why are you making us so emotional? 🐶 i’m not saying it because i’m trying to make you emotional. it is genuinely how i feel. i’m not saying this because i thought, “i have to make them emotional.” it’s true. i really think this way. 🐶 TREASURE MAKERs, you’re all pretty. really.. you’re all pretty. i genuinely think that way.

shan

228,682 次观看 • 13 天前

Naval Ravikant’s checklist for starting a company “The most important thing is there are no formulas. At the end of the day, you have to do what you love, and you have to do it even though people tell you it’ll never work. But that being said, if there was a formula [for starting a company], I would put it something like this.” Naval started seven companies before AngelList and this is the checklist he recommends running through before starting a startup: 1. Pick a great cofounder. This is most important: “You can do a company on your own, but it’s like you can raise a child on your own, but you probably shouldn’t. You need someone who’s going to be there with you.” This has it’s own checklist. Your cofounder should be: a. Very high intelligence (”hopefully they make you feel dumb, or they’re not smart enough”) b. Very high energy (”They should be extremely hardworking. A founder is someone who never has to be motivated. You should not have to be telling them to do their job.”) c. Very high integrity. (”a smart, hardworking crook who’s going to cheat you is the worst kind of person to be paired up with.”) 2. Pick a very large market. “Notice I don’t talk about the idea. I think ideas are almost irrelevant… The more important thing is that you pick a large space that you’re knowledgeable and passionate about. And then you will figure out what the right thing to do within that space is.” You want to be able to say to investors: “This is a space where there’s a huge market. I’m really knowledgeable and passionate about it. Here’s the great person that I have doing it with me. And here’s the minimum viable product that we have built. That will show that we can test in the marketplace… You iterate until you get to product/market fit… And then you go and you raise money from people you trust. And you use that money to scale.”

Startup Archive

36,050 次观看 • 1 年前

The Idea of NHI on Earth. ⬇️⬇️⬇️ 🔥"The gravity of it goes up a whole lot if it goes from the theoretical to the verified." ~Dr. Phil 🔥 "There have been people that have reported being abducted over the years. What's the intent behind that? Is it medical? Is it more nefarious?" ~BZ to Dr. Phil (I'm so glad Bryce went there.) "There will be people...who likely are going to need some some assistance to help deal with this because it is so far-reaching and for some people, potentially, very frightening." ~Mellon ~ Dr. Phil: "We know in the last 80 years there have been no overt hostile acts that we know about. That doesn't mean there could be things happening that are attributable to these forces that we don't know about. But, we certainly don't have any attacks that we can attribute to these UAPs or whatever." (Well, there's Colares in 1977. If that was non-human in nature, I'd say that qualifies as overt. And the Thomas Mantell incident in 1948 where he crashed and died after pursuing a UFO. Was that overt? Unfortunately, we don't know what happened and probably never will.) Dr. Phil: "And if the best predictor of future behavior is past behavior, I think people can take some comfort in knowing that if they were gonna melt us with a ray gun or something of that nature, they've had ample opportunity to do that. "They may have been here 1000 years before we were here. Who knows what the situation is? But we do know that as long as we've been monitoring this and tracking it, there have been no overt hostile acts and I think people can take some comfort in that, and should." (See the work of Peter Levenda for a deeper look at that. "They might have been attacking us for centuries already, in ways that make sense to them... What if they are attacking us through the manipulation of consciousness? ~Peter Levenda More... ⬇️⬇️⬇️ ~ (I'm glad Bryce pushed back a bit.) Bryce Zabel: "They should. The only thing I would say is, if we're dealing with a non-human intelligence - or an NHI, as we like to say now - we'd have to assume that they think differently than us. So even in our own world, in the United States, we tend to think in four-year terms because of presidential terms, right? So you can't get something off the ground if it can't get done right away. The Chinese may think in 100-year terms when they think about Taiwan or whatever. "It's possible there are alien or non-human intelligences that think in a different time frame. If their time frame was 1000 years, then they could just be getting started. "And on the topic of the nuclear issue, which I share concern of. I mean, I think the nuclear issue means it is at least a national-security issue of some kind. Now, I've heard people talk about this, Dr. Phil, two different ways. Some people say, 'Well, you know, they're looking at our nuclear capabilities because they want to protect us from ourselves.' "Okay, that's great, I hope that's true. But the other would be: what do you do before you actually go to war with anybody, is you do reconnaissance. You try to find out what the other guy has. What are their assets? What are their capabilities?" (That may freak out some people but all angles should be considered.) Zabel: "So, I think the problem that we need to overcome in this country is getting to a place where we understand this phenomenon that we're encountering enough that we can at least start to figure out intent. What is the intent? "There have been people that have reported being abducted over the years. What's the intent behind that? Is it medical? Is it more nefarious? What is it? And so, we got a lot of work to do, and I think that's why I am so supportive of your current efforts because you're, basically, saying, 'Let's get started, people. Let's really take this seriously. Let's quit fooling around and stigmatizing people that want to take it seriously, and let's get to work.' But let's get to work as a human race. Let's start sharing what we know and let's make progress. That's where I'm coming from, too." (Bringing up abductions is important because it IS part of this discussion and it shouldn't be avoided. Kudos to Bryce!) Dr. Phil: "I saw a study that said 71% of Americans believe that there are aliens that have been or are in our earthly space. And it's interesting...I read that in one context, it said, 'Look, this is not going to be such a big deal if this gets verified.' "You know, there's one thing to say that in the abstract, like, 'Yeah, I think yeah probably there are.' It's a whole other different situation if you turn around and see somebody standing there. The gravity of it goes up a whole lot if it goes from the theoretical to the verified. (100%. That's my favorite part of the interview and it's so true.) Dr. Phil: "And I hope that we are going to put enough context around this, particularly knowing that there are segments of our population that are very vulnerable. There are some elderly folks that aren't up on technology and might be overwhelmed by the reality of this. "We have certain populations that might be easily disoriented or destabilized in the mental emotional fringes of the population. And I worry about those that are easily exploitable. You know, you need to get out of the urban areas, buy our buried school bus in the mountains, and you'll be safe forever. You know the con artists and the scammers are going to find every opportunity to prey upon those that are concerned and worried about this. "And I think we need to be prepared to take care of those that might be destabilized by this information that's coming out right now, we can't pretend they aren't there. We've made those mistakes in the past, like during COVID, for example. There are those that are more impacted than others, and we need to be prepared to handle that." Christopher K. Mellon: "We, recently, commissioned a study by a group of six psychologists, PhD psychologists, on this topic of how the public would receive this information. And it was generally very encouraging. And what they found was that the great bulk of the population, as they have in the past with other epical changes such as the Copernican principle, or evolution, or general relativity, it takes people a while to process this information. There's a period of resistance. But most people will get up, get out of bed, go to work the next day. They're not devastated, even though there's nothing quite comparable to this, perhaps." (There's no perhaps. A government or respected figure admitting that we're not alone on this planet would be unprecedented and there is NOTHING we can compare it to.) Mellon: "What the study did find is that there is likely, however, to be a subset of people, maybe 15% of the population, that are going to need some help. And that we are not necessarily prepared in our present state to provide that kind of assistance, and we need to be doing more to get ready for that." (If he's talking world population, that's about 1.2 BILLION people who are going to need some help dealing with this. Holy crap. 😬) Mellon: "And also, to work on the messaging. The messaging is so important, clear and consistent messaging from the government, trying to develop trust with the American people so that the information is is accepted and acted on." (For me, I want the whole truth more than the right "message.") Mellon: "A lot of the difference will be people who can't get their head around it, even though they really understand it. But because of their own belief structure, the architecture of their own belief structure, for some reason, in their particular individual case, it's particularly threatening or disruptive. "So there will be people who fall into that category, according to this study, who likely are going to need some some assistance to help deal with this because it is so far-reaching and for some people, potentially, very frightening."

Joe Murgia

31,404 次观看 • 2 个月前

🦖: I don’t feel anything (about the situation). It all started because of my fan and (the post) said “Why do gay tops like to wear Stussy?”. I felt like teasing them so I said “Because it is cool”. Then some people said “But with this style/appearance, you do not seem like a top”. When I express myself, no matter what I am, it is something that came out of my mouth. So I feel that when there are people who would judge, for example, when you stated, “you are a male”, but there is someone who says, “But you are not a male”. How would you know what that person is? isn’t that right? Regarding the topic of gender and preference in terms of your role during intercourse, it is a private and sensitive matter. Since you are not living with them, you have no reason to judge them on whether they are a top or bottom. I feel that we have no right to judge people on these matters. In 2025, everyone can choose who they want to be and in these times, the world is more open-minded. Anything can happen. This kind of thing is fluid and a very personal matter. 🦖: I feel that when it is a very personal and sensitive thing, there might be a certain group of people who are not be comfortable expressing that they are not straight. Besides not being straight, this also includes having to state their sexual preference or their role during intercourse. It is way beyond that. So I feel that if they are comfortable expressing who they are, but you just feel that their outward appearance does not align with what you think, and then you judge them by saying “But this is not right, this appearance should be a bottom. There is no way.” How would you know? Isn’t that right? OUROAD AT SIAM PARAGON #SiamParagonSummer2025xOUROAD #ต้าห์อู๋ #Daou #Oueiija
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Sensitive content

🦖: I don’t feel anything (about the situation). It all started because of my fan and (the post) said “Why do gay tops like to wear Stussy?”. I felt like teasing them so I said “Because it is cool”. Then some people said “But with this style/appearance, you do not seem like a top”. When I express myself, no matter what I am, it is something that came out of my mouth. So I feel that when there are people who would judge, for example, when you stated, “you are a male”, but there is someone who says, “But you are not a male”. How would you know what that person is? isn’t that right? Regarding the topic of gender and preference in terms of your role during intercourse, it is a private and sensitive matter. Since you are not living with them, you have no reason to judge them on whether they are a top or bottom. I feel that we have no right to judge people on these matters. In 2025, everyone can choose who they want to be and in these times, the world is more open-minded. Anything can happen. This kind of thing is fluid and a very personal matter. 🦖: I feel that when it is a very personal and sensitive thing, there might be a certain group of people who are not be comfortable expressing that they are not straight. Besides not being straight, this also includes having to state their sexual preference or their role during intercourse. It is way beyond that. So I feel that if they are comfortable expressing who they are, but you just feel that their outward appearance does not align with what you think, and then you judge them by saying “But this is not right, this appearance should be a bottom. There is no way.” How would you know? Isn’t that right? OUROAD AT SIAM PARAGON #SiamParagonSummer2025xOUROAD #ต้าห์อู๋ #Daou #Oueiija

𝐟𝐢𝐥𝐦.

249,277 次观看 • 1 年前

Q: How will I know when it’s the right time to go full-time on a startup idea? Tony Fadell is the co-creator of the iPod, iPhone, and Nest. As he puts it in the clip below: “Great ideas chase you.” He continues: “In this world, there are so many people who have more ideas than they have time to implement… I used to be like that. But the best ideas are the ones that you can really focus on… Now I try to run away from a great idea. And then it stalks me. It hunts you down because you’re like: ‘Ah, that’s going to have this problem, I’m going to put it aside.’ And then a few days later, you’re like: ‘Actually I think I know how to solve that problem.’ At some point it just becomes this black hole that sucks you in and you can’t think about anything else but this.” Mark Zuckerberg gave similar advice in a previous Startup Archive answer: “I always think the most important thing entrepreneurs should do is pick something they care about and work on it, but don’t actually commit to turning it into a company until it’s working. If you look at the data of the very best companies, I think a tremendous percentage of them have been built that way and not from people who decided upfront that they wanted to start a company because you just get locked into a local maxima a lot of the time.” Let great ideas chase you and don’t turn it into a company until it’s working. There’s almost always a ton of work you you can do upfront to de-risk an idea before turning it into a company. And perhaps just as important: you want to make sure you’re still excited about the idea after a few months and the novelty has worn off—it should be all you can think about. Companies are almost always a 10 year project if they work and a 2-3 year project if they fail. It’s worth it to be patient before jumping in with two feet.

Michael McGuiness

62,662 次观看 • 2 年前

Steve Jobs on how to build a great brand After re-joining Apple in 1996, Steve Jobs announced the “Think different” campaign with the following statement: “To me, marketing is about values. This is a very complicated and noisy world. We’re not going to get a chance to get people to remember much about us. No company is. So we have to be really clear on what we want them to know about us.” He cites Nike as one of the greatest jobs of marketing the universe has ever seen: “Remember, Nike sells a commodity—they sell shoes! And yet when you think of Nike, you feel something different than a shoe company. In their ads, they don’t ever talk about the product. They don’t ever tell you about their air soles and why they are better than Reebok’s air soles. What does Nike do in their advertising? They honor great athletes, and they honor great athletics. That’s who they are, that’s what they are about.” Marketing guru Seth Godin also used Nike as an example of great branding in a blog post a few years ago: “If Nike announced that they were opening a hotel, you’d have a pretty good guess about what it would be like. But if Hyatt announced that they were going to start making shoes, you would have NO IDEA WHATSOEVER what those shoes would be like. That’s because Nike owns a brand and Hyatt simply owns real estate.” Jobs goes on to explain how the Apple team arrived at the “Think Different” campaign: “Our customers want to know who is Apple and what is it that we stand for. Where do we fit in this world? What we’re about isn’t making boxes for people to get their jobs done—although we do that well. We do that better than almost anybody, in some cases. But Apple is about something more than that. Apple at the core—its core value—is that we believe people with passion can change the world for the better… And that those people who are crazy enough to think that they can change the world are the ones who actually do.” He continues: “And so, what we’re going to do in our first brand marketing campaign in several years is to get back to that core value. A lot of things have changed. The market is in a totally different place than it was a decade ago, and Apple is totally different… the products and the distribution strategy and the manufacturing are totally different. And we understand that. But values and core values—those things shouldn’t change. The things that Apple believed in, at its core, are the same things that Apple really stands for today.” Apple’s “Think Different” campaign was designed to honor those people who have changed the world. And as Jobs so eloquently put it: “Some of them are living. Some of them are not. But the ones that aren’t, you’ll know that if they ever used a computer, it would’ve been a Mac. The theme of the campaign is ‘Think Different.’ It’s honoring the people who think different and who move this world forward. And it is what we are about. It touches the soul of this company.” If you’re looking to create a great brand, I’d start out by asking: what are your core values and what does your company honor?

Startup Archive

338,105 次观看 • 2 年前