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Between 1960 and 2015, Americans’ life expectancy increased by almost 10 years. So, why are we all convinced that modern life is poisoning us?

692,462 views • 6 months ago •via X (Twitter)

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Nick Lane has a theory about the evolution of life which explains *why* life is the way that it is - all the contingent mechanisms you’re just supposed to take as givens in biology class. He thinks early life was continuous with the spontaneous chemistry of deepsea hydrothermal vents. I find it remarkable that with just that starting point, he can potentially explain so much: - Why are there two sexes? Why sex at all? - Why are bacteria so relatively simple despite being around for 4 billion years? Why is there so much shared structure between all eukaryotic cells despite the enormous morphological variety between animals, plants, fungi, and protists? - Why did the endosymbiosis event that led to eukaryotes happen only once, and in the particular way that it did? - Why is all life powered by proton gradients? Why does all life on Earth share not only the Krebs Cycle, but even the intermediate molecules like Acetyl-CoA? His theory implies that early life is almost chemically inevitable (potentially blooming on hundreds of millions of planets in the Milky Way alone, and based the very same chemical metabolism). The real bottleneck for intelligent life ready to explore the cosmos, in his view, is the eukaryotic cell. 0:00:00 – The singularity that unlocked complex life 0:09:10 – Early life continuous with Earth's geochemistry 0:24:20 – Eukaryotes are the great filter for intelligent life 0:43:00 – Mitochondria are the reason we have sex 1:08:56 – Are bioelectric fields linked to consciousness?

Dwarkesh Patel

124,712 views • 10 months ago