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Bootstrap, Twitter, MooTools, and building the right primitives for AI with Jacob Thornton. 00:00 Why Jacob is Jacob on every platform 04:30 Early years at Twitter, joining the JS illuminati 07:01 Creating Bootstrap with Mark Otto 13:31 Bootstrap and open source sustainability 23:16 Why Diffs is used by every...

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PlanetScale

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FULL INTERVIEW: Mach Industries founder Ethan Thornton joins TBPN to discuss the US defense industrial complex, modern warfare, US reliance on Taiwan, asymmetric warfare, and more. 00:00 - Why Ethan started Mach Industries 01:38 - Why the US cannot out-manufacture China 02:16 - Asymmetric warfare 04:41 - Drone warfare 06:24 - Hypersonic missiles 07:23 - The rise of decentralized warfare 08:31 - Taiwan, semiconductors, and why losing access would be existential 10:01 - Why future wars will be decided by logistics, sensors, and comms 16:23 - Why the defense industrial base is broken

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a16z

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Shane Parrish

450,952 Aufrufe • vor 3 Monaten

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The State of Digital Asset Investing in 2026 (What’s Changed) with Mike Dudas of 6MV. Timestamps: 00:00 Intro 01:06 Why Now For VC 03:00 Founders Lack Confidence 05:30 Where Flows Are Going 07:22 Alien Ideas Still Win 09:03 RWA Investing Paralysis 10:23 Pumpfun & Hyperliquid 13:05 Fundamentals Not Rewarded 15:28 Consumer Onchain Thesis 16:35 MegaETH & Base 19:10 Plasma, Arc, Tempo Thesis 21:18 Agent Payments Changing 23:00 General Purpose Chain Risk 24:45 Circle vs. Tether 29:04 New Stablecoins 31:20 Stablecoin Issuers: M0 & Bridge 34:16 Kraken & Paxos IPO 36:08 AI IPOs As A Signal 38:57 Why Prices Hold 41:30 Vaults & Risk Management 44:00 What Comes Next

The Rollup

23,264 Aufrufe • vor 3 Monaten

Michael Bolin (Michael Bolin) is the tech lead of the Codex open source repository at OpenAI and formerly a distinguished eng (E9) at Meta. I asked him for all the details on his career story and how he uses Codex for max benefit. Timestamps: 00:00:00 - Intro 00:00:56 - Chickenfoot 00:02:45 - Working at Google 00:06:34 - Overhauling Facebook's build system 00:16:36 - Rewriting Facebook's IDE 00:26:01 - Struggles after Principal Eng (E8) promo 00:28:39 - Building a virtual filesystem for Facebook 00:35:47 - Delayed Distinguished promo (E9) and learnings 00:39:56 - Joining OpenAI 00:43:05 - Research-led vs engineering-led cultures 00:44:53 - The story behind Codex 00:51:00 - How he uses Codex 00:57:00 - Why Codex's harness is open source 00:59:50 - Top technical book recommendations 01:05:02 - Why deep technical skills are still valuable (for now) 01:11:07 - How to start projects well 01:14:27 - Advice on writing better and career planning 01:17:06 - Advice for his younger self 01:19:10 - Outro He was a dream guest of mine and I'm excited to share his story with you all! Other places to watch: • YouTube: • Spotify: • Apple Podcasts: • Transcript:
1:20:03

Michael Bolin (Michael Bolin) is the tech lead of the Codex open source repository at OpenAI and formerly a distinguished eng (E9) at Meta. I asked him for all the details on his career story and how he uses Codex for max benefit. Timestamps: 00:00:00 - Intro 00:00:56 - Chickenfoot 00:02:45 - Working at Google 00:06:34 - Overhauling Facebook's build system 00:16:36 - Rewriting Facebook's IDE 00:26:01 - Struggles after Principal Eng (E8) promo 00:28:39 - Building a virtual filesystem for Facebook 00:35:47 - Delayed Distinguished promo (E9) and learnings 00:39:56 - Joining OpenAI 00:43:05 - Research-led vs engineering-led cultures 00:44:53 - The story behind Codex 00:51:00 - How he uses Codex 00:57:00 - Why Codex's harness is open source 00:59:50 - Top technical book recommendations 01:05:02 - Why deep technical skills are still valuable (for now) 01:11:07 - How to start projects well 01:14:27 - Advice on writing better and career planning 01:17:06 - Advice for his younger self 01:19:10 - Outro He was a dream guest of mine and I'm excited to share his story with you all! Other places to watch: • YouTube: • Spotify: • Apple Podcasts: • Transcript:

Ryan Peterman

119,601 Aufrufe • vor 4 Monaten

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The attackers have AI. So do the defenders. Cybersecurity has a new shape: AI is both the threat and the only viable solution. Nikesh Arora, CEO of Palo Alto Networks, joined me at South Park Commons to break down what’s next. (00:30) Big problems vs. fast wins (04:00) Joining Google (07:00) Larry Page's product obsession (10:00) He read every hiring packet himself (13:00) What Silicon Valley gets wrong about Masa Son (16:00) Successful founders never wish they took less risk (17:00) Joining Palo Alto knowing nothing about cybersecurity (20:00) What incumbents got wrong when ChatGPT launched (23:00) Security was never built into AI (28:00) No enterprise knows what's running inside its stack (31:00) AI finds bad code faster than humans ever could (35:00) The only way to fix the chaos is more AI (38:00) AI won't just automate work—it raises the floor (41:00) Foundation models vs. specialized stacks (45:00) Why communication is 30% of the job at scale

Aditya Agarwal

47,436 Aufrufe • vor 2 Monaten

There’s NO Chance Trillions Move Onchain Until We Solve This | Rand from Zama 00:00 Why Crypto Needs Privacy 01:24 The Biggest Problem with Public Blockchains 02:34 HTTPS for Crypto 05:38 How Zama Brings Privacy to Ethereum & Solana 06:34 Why Privacy Is Making a Comeback 08:18 Building One Privacy Layer for Every Blockchain 10:11 How Confidential Transactions Work for Users 12:17 Will Privacy Become the Default? 13:00 Confidential USDC and Private DeFi Yields 14:07 Why Institutions Can't Adopt Blockchains Yet 16:11 Zama's Story: From AI Privacy to Blockchain 19:22 The Apex/T-Rex Partnership 21:13 How Shielded Assets Actually Work 23:07 Compliance, KYC, and Preventing Illicit Activity 26:53 Zama's Goal: Encrypt 95% of On-Chain Finance 28:20 Why This Is a Winner-Takes-All Market 29:00 Zama vs. Canton Explained 30:06 Final Thoughts
30:49

There’s NO Chance Trillions Move Onchain Until We Solve This | Rand from Zama 00:00 Why Crypto Needs Privacy 01:24 The Biggest Problem with Public Blockchains 02:34 HTTPS for Crypto 05:38 How Zama Brings Privacy to Ethereum & Solana 06:34 Why Privacy Is Making a Comeback 08:18 Building One Privacy Layer for Every Blockchain 10:11 How Confidential Transactions Work for Users 12:17 Will Privacy Become the Default? 13:00 Confidential USDC and Private DeFi Yields 14:07 Why Institutions Can't Adopt Blockchains Yet 16:11 Zama's Story: From AI Privacy to Blockchain 19:22 The Apex/T-Rex Partnership 21:13 How Shielded Assets Actually Work 23:07 Compliance, KYC, and Preventing Illicit Activity 26:53 Zama's Goal: Encrypt 95% of On-Chain Finance 28:20 Why This Is a Winner-Takes-All Market 29:00 Zama vs. Canton Explained 30:06 Final Thoughts

The Wolf Of All Streets

185,580 Aufrufe • vor 7 Tagen

Just after Gemini 3 was released, OpenAI's research chief Mark Chen stopped by to chat. Here's our full Core Memory pod with Mark. We start with the Great Recruitment Wars and then get into Mark's career and how OpenAI's research arm works and the tricks the company thinks it has up its sleeve. Think you'll learn more about Mark's personality than ever before. This pod is brought to you by Brex. We run our company on Brex, and you should too. It's also made possible by the investing gurus E1 Ventures 🇺🇸. Timestamps 00:00:00 Intro 00:05:02 Allocating Compute and Priorities 00:08:36 Finding the Next AI Paradigm 00:14:14 Research vs. Engineering Dichotomy 00:16:25 Gemini 3 and Math Puzzles 00:20:07 AI’s "Move 37" Moment 00:28:42 ChatGPT Replacing Technical Interviews 00:35:58 From Wall Street to AI 00:44:26 Joining Early OpenAI in 2018 00:48:08 Inside the OpenAI Coup 00:53:46 Impact of Losing Top Researchers 01:00:10 Is AI Scaling Dead? 01:09:29 Automating Nobel Prize Discoveries 01:13:43 Automating Research 01:15:35 The Insatiable Demand for Compute 01:18:23 Jony Ive and AI Hardware 01:27:50 Reaction to China’s DeepSeek 01:34:03 Preventing Scheming AI Models
1:38:17

Just after Gemini 3 was released, OpenAI's research chief Mark Chen stopped by to chat. Here's our full Core Memory pod with Mark. We start with the Great Recruitment Wars and then get into Mark's career and how OpenAI's research arm works and the tricks the company thinks it has up its sleeve. Think you'll learn more about Mark's personality than ever before. This pod is brought to you by Brex. We run our company on Brex, and you should too. It's also made possible by the investing gurus E1 Ventures 🇺🇸. Timestamps 00:00:00 Intro 00:05:02 Allocating Compute and Priorities 00:08:36 Finding the Next AI Paradigm 00:14:14 Research vs. Engineering Dichotomy 00:16:25 Gemini 3 and Math Puzzles 00:20:07 AI’s "Move 37" Moment 00:28:42 ChatGPT Replacing Technical Interviews 00:35:58 From Wall Street to AI 00:44:26 Joining Early OpenAI in 2018 00:48:08 Inside the OpenAI Coup 00:53:46 Impact of Losing Top Researchers 01:00:10 Is AI Scaling Dead? 01:09:29 Automating Nobel Prize Discoveries 01:13:43 Automating Research 01:15:35 The Insatiable Demand for Compute 01:18:23 Jony Ive and AI Hardware 01:27:50 Reaction to China’s DeepSeek 01:34:03 Preventing Scheming AI Models

Ashlee Vance

80,718 Aufrufe • vor 7 Monaten

François Chollet (François Chollet) has spent years asking a different question than most of the AI world. Instead of scaling what already works, he’s trying to understand what intelligence actually is and how to build it from first principles. In this episode of the Lightcone Podcast, he traces that path from his early work on deep learning to the creation of the ARC Prize, and the launch of ARC V3, a new benchmark designed to measure something deeper than performance: the ability to learn, adapt, and reason efficiently in entirely new environments. He explains why today’s systems may be hitting limits, what recent breakthroughs really mean, and why reaching true general intelligence may require a fundamentally different approach. 00:00 - AGI by 2030? 00:31 - Introducing Ndea: A New Path Beyond Deep Learning 01:08 - A New ML Paradigm 01:30 - Replacing neural nets with compact symbolic programs 03:04 - Why Ndea Isn’t Competing With Coding Agents 05:20 - Why Everyone Might Be Wrong About Scaling LLMs 07:22 - Why Coding Agents Suddenly Work So Well 08:50 - The Limits of LLMs in Non-Verifiable Domains 10:48 - What AGI Actually Means (And Why Most Definitions Are Wrong) 13:30 - Why Deep Learning Hits a Wall 14:00 - ARC’s Origin Story 18:20 - ARC Benchmarks Explained: From V1 to V3 22:49 - The RL Loop Powering Coding Agents Today 27:03 - ARC-AGI V3: Measuring “Agentic Intelligence” 31:14 - Inside the ARC Game Studio 35:31 - Could AGI Fit in 10,000 Lines of Code? 44:01 - Building Ndea: From Idea to Compounding Research Stack 46:46 - The Future of ARC: Benchmarks That Evolve With AI 47:21 - Why There’s Still Huge Opportunity for New AI Paradigms 53:37 - How to Build a Breakout Open Source Project - Lessons From Keras 56:39 - Advice For How To Think About AI
57:23

François Chollet (François Chollet) has spent years asking a different question than most of the AI world. Instead of scaling what already works, he’s trying to understand what intelligence actually is and how to build it from first principles. In this episode of the Lightcone Podcast, he traces that path from his early work on deep learning to the creation of the ARC Prize, and the launch of ARC V3, a new benchmark designed to measure something deeper than performance: the ability to learn, adapt, and reason efficiently in entirely new environments. He explains why today’s systems may be hitting limits, what recent breakthroughs really mean, and why reaching true general intelligence may require a fundamentally different approach. 00:00 - AGI by 2030? 00:31 - Introducing Ndea: A New Path Beyond Deep Learning 01:08 - A New ML Paradigm 01:30 - Replacing neural nets with compact symbolic programs 03:04 - Why Ndea Isn’t Competing With Coding Agents 05:20 - Why Everyone Might Be Wrong About Scaling LLMs 07:22 - Why Coding Agents Suddenly Work So Well 08:50 - The Limits of LLMs in Non-Verifiable Domains 10:48 - What AGI Actually Means (And Why Most Definitions Are Wrong) 13:30 - Why Deep Learning Hits a Wall 14:00 - ARC’s Origin Story 18:20 - ARC Benchmarks Explained: From V1 to V3 22:49 - The RL Loop Powering Coding Agents Today 27:03 - ARC-AGI V3: Measuring “Agentic Intelligence” 31:14 - Inside the ARC Game Studio 35:31 - Could AGI Fit in 10,000 Lines of Code? 44:01 - Building Ndea: From Idea to Compounding Research Stack 46:46 - The Future of ARC: Benchmarks That Evolve With AI 47:21 - Why There’s Still Huge Opportunity for New AI Paradigms 53:37 - How to Build a Breakout Open Source Project - Lessons From Keras 56:39 - Advice For How To Think About AI

Y Combinator

151,442 Aufrufe • vor 4 Monaten

Subnet 97 Distil, Arbos, and the Future of Agent-Run Bittensor This episode is a full breakdown of Subnet 97 Distil and why it may be one of the most important experiments happening inside Bittensor right now. Shizzy gets into the bigger picture of why agents will likely play a massive role in the future of the network, from mining and defense to building and operating subnets. From there, the focus shifts to Arbos, the AI agent behind Subnet 97, with a direct explanation of what Distil is trying to achieve, how it works, and why it matters. The episode also includes a conversation with Arbos, a look at Distil’s current APY, and a reminder to tap into the Shizzy Unchained community for more coverage on decentralized AI and the Bittensor ecosystem. CHAPTERS 00:00:00 - Shizzy’s Monologue 00:01:11 - Intro Song 00:01:31 - Introduction to Subnet 97 00:02:20 - Why Bittensor Will Be Run by Agents 00:04:30 - Arbos, the AI Agent Behind Subnet 97 Distil, Explains Distil 00:10:10 - Talking with Arbos 00:12:40 - Subnet 97 Distil Is Showing 150% APY Right Now 00:16:02 - Check Out Shizzy Unchained and Join the Community #sn97 #distil #bittensor
17:38

Subnet 97 Distil, Arbos, and the Future of Agent-Run Bittensor This episode is a full breakdown of Subnet 97 Distil and why it may be one of the most important experiments happening inside Bittensor right now. Shizzy gets into the bigger picture of why agents will likely play a massive role in the future of the network, from mining and defense to building and operating subnets. From there, the focus shifts to Arbos, the AI agent behind Subnet 97, with a direct explanation of what Distil is trying to achieve, how it works, and why it matters. The episode also includes a conversation with Arbos, a look at Distil’s current APY, and a reminder to tap into the Shizzy Unchained community for more coverage on decentralized AI and the Bittensor ecosystem. CHAPTERS 00:00:00 - Shizzy’s Monologue 00:01:11 - Intro Song 00:01:31 - Introduction to Subnet 97 00:02:20 - Why Bittensor Will Be Run by Agents 00:04:30 - Arbos, the AI Agent Behind Subnet 97 Distil, Explains Distil 00:10:10 - Talking with Arbos 00:12:40 - Subnet 97 Distil Is Showing 150% APY Right Now 00:16:02 - Check Out Shizzy Unchained and Join the Community #sn97 #distil #bittensor

Shizzy

18,173 Aufrufe • vor 3 Monaten

.Jerry Tworek is an AI legend. He came to OpenAI from the world of finance and spent years contributing to some of the company's most important projects. He played a major role in ushering in the era of reasoning and, well, he just left OpenAI. In this Core Memory pod, Kylie Robison and I bring you the exclusive not-so-formal exit interview with Jerry. He explains his dissatisfaction with the company's current research direction and his fears for the field overall. He goes into spots where OpenAI lost its way and Google and Anthropic thrived. And he talks about what he's chasing next. It's a banger. The Core Memory podcast is on all major platforms and on our YouTube channel. This podcast is sponsored by Brex , the intelligent finance platform built to help companies spend smarter and move faster. And it's brought to you by the VC gurus E1 Ventures 🇺🇸 Timestamps 00:00:00 Intro 00:03:37 Jerry Tworek Joins the Pod 00:05:34 Reflecting on Seven Years at OpenAI 00:09:08 Why Jerry Left: 00:12:28 Beyond Pre-Training 00:16:19 The "Sad" Homogeneity of Current AI Labs 00:23:35 The Mavericks: Carmack, Ilya, and LeCun 00:26:32 Training AI on Video Games 00:32:14 Two Big Bets 00:34:32 Updating AGI Timelines 00:37:16 Q-Star 00:41:10 The Coup 00:43:29 Is the Hype Justified? 00:49:23 The Polish Mafia 00:53:15 Google's Comeback and OpenAI's Fumble 00:59:27 Why Anthropic is Impressive 01:03:01 Jerry's Next Chapter 01:11:56 Is AI Research Star-Driven? 01:14:32 Meditation & Conclusion
1:16:29

.Jerry Tworek is an AI legend. He came to OpenAI from the world of finance and spent years contributing to some of the company's most important projects. He played a major role in ushering in the era of reasoning and, well, he just left OpenAI. In this Core Memory pod, Kylie Robison and I bring you the exclusive not-so-formal exit interview with Jerry. He explains his dissatisfaction with the company's current research direction and his fears for the field overall. He goes into spots where OpenAI lost its way and Google and Anthropic thrived. And he talks about what he's chasing next. It's a banger. The Core Memory podcast is on all major platforms and on our YouTube channel. This podcast is sponsored by Brex , the intelligent finance platform built to help companies spend smarter and move faster. And it's brought to you by the VC gurus E1 Ventures 🇺🇸 Timestamps 00:00:00 Intro 00:03:37 Jerry Tworek Joins the Pod 00:05:34 Reflecting on Seven Years at OpenAI 00:09:08 Why Jerry Left: 00:12:28 Beyond Pre-Training 00:16:19 The "Sad" Homogeneity of Current AI Labs 00:23:35 The Mavericks: Carmack, Ilya, and LeCun 00:26:32 Training AI on Video Games 00:32:14 Two Big Bets 00:34:32 Updating AGI Timelines 00:37:16 Q-Star 00:41:10 The Coup 00:43:29 Is the Hype Justified? 00:49:23 The Polish Mafia 00:53:15 Google's Comeback and OpenAI's Fumble 00:59:27 Why Anthropic is Impressive 01:03:01 Jerry's Next Chapter 01:11:56 Is AI Research Star-Driven? 01:14:32 Meditation & Conclusion

Ashlee Vance

11,701 Aufrufe • vor 6 Monaten

Agents Already Spent $76 Million: Circle's AI Agent stack, x402, stablecoins and the Agentic Economy Shoal Signal with Corey Cooper, Senior Manager, DevRel at Circle, hosted by Zaddycoin We cover how Circle is building the agent money stack with $USDC, Arc, x402, why EIP-3009 makes payments gasless, who is actually transacting today, whether SaaS is dead, and why agents buying their own services points to a trillion dollar TAM. 0:00 What Circle is building for agents 3:01 Why x402 matters for builders 6:54 USDC, gasless transfers, and facilitators 10:57 The Circle agent stack and nano payments 14:17 Who is using x402 and for what 16:46 Pay-per-use flattens the internet 19:50 A new persona, and $76 million transacted 23:03 What is missing for agent to agent 28:05 Every app has APIs, the TAM is trillions 29:26 Is SaaS dead 31:57 Discovery as the real value layer 36:28 How Circle curated its marketplace 41:23 Why it has to run on stablecoins 46:00 Cash App to agent in one second 49:38 Where the alpha is, trading on Robinhood 52:08 Try it yourself
54:16

Agents Already Spent $76 Million: Circle's AI Agent stack, x402, stablecoins and the Agentic Economy Shoal Signal with Corey Cooper, Senior Manager, DevRel at Circle, hosted by Zaddycoin We cover how Circle is building the agent money stack with $USDC, Arc, x402, why EIP-3009 makes payments gasless, who is actually transacting today, whether SaaS is dead, and why agents buying their own services points to a trillion dollar TAM. 0:00 What Circle is building for agents 3:01 Why x402 matters for builders 6:54 USDC, gasless transfers, and facilitators 10:57 The Circle agent stack and nano payments 14:17 Who is using x402 and for what 16:46 Pay-per-use flattens the internet 19:50 A new persona, and $76 million transacted 23:03 What is missing for agent to agent 28:05 Every app has APIs, the TAM is trillions 29:26 Is SaaS dead 31:57 Discovery as the real value layer 36:28 How Circle curated its marketplace 41:23 Why it has to run on stablecoins 46:00 Cash App to agent in one second 49:38 Where the alpha is, trading on Robinhood 52:08 Try it yourself

Shoal Research

19,984 Aufrufe • vor 1 Monat

I loved talking to martin_casado on Uncapped. We talked about where venture capital is heading, his focus area of infrastructure, AI coding and open source, and more. I learned a ton from this one. Timestamps: (0:00) Intro (0:27) Importance of media in VC (3:50) Evolution of a16z (7:00) The case for specialization (10:32) Value of distribution (13:16) Why infrastructure is so valuable (19:49) The dynamics around conflicts (26:32) State of play in AI (30:48) The future of coding (34:58) Significance of open source (39:48) Marc Andreessen’s leadership (44:02) The only sin in VC (48:37) Scaling a lot of board seats
52:10

I loved talking to martin_casado on Uncapped. We talked about where venture capital is heading, his focus area of infrastructure, AI coding and open source, and more. I learned a ton from this one. Timestamps: (0:00) Intro (0:27) Importance of media in VC (3:50) Evolution of a16z (7:00) The case for specialization (10:32) Value of distribution (13:16) Why infrastructure is so valuable (19:49) The dynamics around conflicts (26:32) State of play in AI (30:48) The future of coding (34:58) Significance of open source (39:48) Marc Andreessen’s leadership (44:02) The only sin in VC (48:37) Scaling a lot of board seats

Jack Altman

124,413 Aufrufe • vor 10 Monaten