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"Aging is the process of a complex system slowly falling into its chaotic disequilibrium. And it's not like evolution necessarily even set a lifespan for us. It is merely the result of, once the system has been established, how long its intrinsic property stayed ordered before it became disordered."...

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Sabrina Halper

16,680 subscribers

22,082 Aufrufe • vor 4 Monaten •via X (Twitter)

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9 Kommentare

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Sabrina Halpervor 4 Monaten

YouTube:

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Sabrina Halpervor 4 Monaten

Spotify:

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Sabrina Halpervor 4 Monaten

Apple:

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henrique cunhavor 4 Monaten

awesome conversation @jacobkimmel has such a clear view and communication, really engaging to hear! and you're a great interviewer as well

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spncejetvor 4 Monaten

Great interview, he is very smart.

Profilbild von Nima Alidoust
Nima Alidoustvor 4 Monaten

Good conversation!

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Antiagngvor 4 Monaten

Basically his view is that we will get like 10% more life quality?

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Hadivor 4 Monaten

isn’t there some jelly fish that is not dying?

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Sabrina Halpervor 4 Monaten

We discuss that jellyfish:)

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Aidan Gomez (Aidan Gomez) is a computer scientist, co-author of the seminal paper ‘Attention Is All You Need,’ and the CEO of Cohere. In this episode, we discussed his upbringing in the cabin his grandfather built in Codrington, a small town North of Brighton, and the values that were instilled in him through his family. We explored his path from Codrington to his undergraduate studies at the University of Toronto, emailing Geoffrey Hinton, and joining Google Brain where he co-wrote the paper on transformers. We discussed how he met his co-founders Ivan Zhang and Nick Frosst, and his insights on what it means to build a meaningful, successful company in Canada. Aidan shares his conviction about what is at stake — for Canada and for the world at large. This is a conversation about family, values, and what it means to live with conviction. The Other Stuff is hosted by internetVin — filmmaker, entrepreneur, and possibly the most curious man on Earth. Produced by New. The Other Stuff #29 — Aidan Gomez: Empathy and Conviction — Timestamps 00:00:00 Intro 00:03:10 The Malleability of Toronto 00:11:06 Growing Up in Codrington 00:13:50 The Story of Aidan Gomez’s Family 00:27:23 Introduction to the Internet 00:30:39 Values and Work Ethic 00:35:46 University of Toronto’s AI Scene 00:40:48 Emailing Geoffrey Hinton 00:42:16 Google Brain 00:45:15 Dropout: A Simple Way to Prevent Neural Networks from Overfitting 00:49:48 The Beauty of Research 00:54:24 One Model to Rule Them All 00:59:54 Meeting Ivan Zhang and Nick Frosst 01:04:00 The Birth of Cohere 01:06:56 Twitter Influencers and Alex Friedland 01:11:48 Being the CEO 01:12:51 Building for Canada 01:15:01 Three Fundamental Ingredients of Building a Company 01:21:39 Working with the Canadian Government 01:24:39 Reflexivity in Canada 01:36:22 What Is Evil? 01:42:40 The Role of AI in the World
1:46:27

Aidan Gomez (Aidan Gomez) is a computer scientist, co-author of the seminal paper ‘Attention Is All You Need,’ and the CEO of Cohere. In this episode, we discussed his upbringing in the cabin his grandfather built in Codrington, a small town North of Brighton, and the values that were instilled in him through his family. We explored his path from Codrington to his undergraduate studies at the University of Toronto, emailing Geoffrey Hinton, and joining Google Brain where he co-wrote the paper on transformers. We discussed how he met his co-founders Ivan Zhang and Nick Frosst, and his insights on what it means to build a meaningful, successful company in Canada. Aidan shares his conviction about what is at stake — for Canada and for the world at large. This is a conversation about family, values, and what it means to live with conviction. The Other Stuff is hosted by internetVin — filmmaker, entrepreneur, and possibly the most curious man on Earth. Produced by New. The Other Stuff #29 — Aidan Gomez: Empathy and Conviction — Timestamps 00:00:00 Intro 00:03:10 The Malleability of Toronto 00:11:06 Growing Up in Codrington 00:13:50 The Story of Aidan Gomez’s Family 00:27:23 Introduction to the Internet 00:30:39 Values and Work Ethic 00:35:46 University of Toronto’s AI Scene 00:40:48 Emailing Geoffrey Hinton 00:42:16 Google Brain 00:45:15 Dropout: A Simple Way to Prevent Neural Networks from Overfitting 00:49:48 The Beauty of Research 00:54:24 One Model to Rule Them All 00:59:54 Meeting Ivan Zhang and Nick Frosst 01:04:00 The Birth of Cohere 01:06:56 Twitter Influencers and Alex Friedland 01:11:48 Being the CEO 01:12:51 Building for Canada 01:15:01 Three Fundamental Ingredients of Building a Company 01:21:39 Working with the Canadian Government 01:24:39 Reflexivity in Canada 01:36:22 What Is Evil? 01:42:40 The Role of AI in the World

The Other Stuff

45,726 Aufrufe • vor 10 Monaten

Bitcoin Could Reach $400K By 2030 | Brian Armstrong 00:00 The Clarity Act and Why It Failed 02:01 The Ethics Issue That Killed the Bill 04:01 Why Democrats Opposed Crypto Regulation 06:01 What Happens to the Clarity Act Now? 08:01 The Risk of Crypto Regulation Without Legislation 10:01 Perpetual Futures and the Future of Markets 16:01 Why the SEC’s New Rules Could Change Crypto 18:01 Coinbase’s Vision for the Future of Finance 22:01 Stablecoins and the Future of Payments 24:01 Why Bitcoin Is Still the Core of Crypto 26:01 Coinbase’s Vision for Onchain Finance 28:01 AI Agents and the Future of Crypto 30:01 AI, Crypto and the Next Financial System 32:01 Why Crypto Needs Better Industry Cooperation 34:01 The Future of Bitcoin and Crypto Adoption 36:01 Why the Next Crypto Cycle Could Be Different 37:56 Final Thoughts
39:38

Bitcoin Could Reach $400K By 2030 | Brian Armstrong 00:00 The Clarity Act and Why It Failed 02:01 The Ethics Issue That Killed the Bill 04:01 Why Democrats Opposed Crypto Regulation 06:01 What Happens to the Clarity Act Now? 08:01 The Risk of Crypto Regulation Without Legislation 10:01 Perpetual Futures and the Future of Markets 16:01 Why the SEC’s New Rules Could Change Crypto 18:01 Coinbase’s Vision for the Future of Finance 22:01 Stablecoins and the Future of Payments 24:01 Why Bitcoin Is Still the Core of Crypto 26:01 Coinbase’s Vision for Onchain Finance 28:01 AI Agents and the Future of Crypto 30:01 AI, Crypto and the Next Financial System 32:01 Why Crypto Needs Better Industry Cooperation 34:01 The Future of Bitcoin and Crypto Adoption 36:01 Why the Next Crypto Cycle Could Be Different 37:56 Final Thoughts

The Wolf Of All Streets

79,578 Aufrufe • vor 1 Monat

I interviewed Aubrey de Grey on why neither billionaires nor AI will solve aging. And why a single mouse breakthrough could be the ChatGPT moment for longevity. 0:00 - Longevity Field 20 Years On 08:58 - Are Billionaires Getting It Wrong? 17:13 - Bryan Johnson vs Peter Thiel 23:42 - ChatGPT Moment for Longevity 28:52 - Biological Age vs Lifespan 34:44 - Influencers Will Save Us 39:36 - AI x Science Breakthroughs 48:14 - Sam Altman on Aging 53:39 - Genesis Mission 56:45 - Systems Will Collapse 1:08:55 - GLP-1s & Human Enhancement
1:15:30

I interviewed Aubrey de Grey on why neither billionaires nor AI will solve aging. And why a single mouse breakthrough could be the ChatGPT moment for longevity. 0:00 - Longevity Field 20 Years On 08:58 - Are Billionaires Getting It Wrong? 17:13 - Bryan Johnson vs Peter Thiel 23:42 - ChatGPT Moment for Longevity 28:52 - Biological Age vs Lifespan 34:44 - Influencers Will Save Us 39:36 - AI x Science Breakthroughs 48:14 - Sam Altman on Aging 53:39 - Genesis Mission 56:45 - Systems Will Collapse 1:08:55 - GLP-1s & Human Enhancement

Mgoes (bio/acc 🤖💉)

45,468 Aufrufe • vor 9 Monaten

The one and only Nikita Bier is today's guest on Out of Office. He's X's head of product, a Lightspeed venture partner, and the world's leading expert on consumer product growth. He and I recently had a long conversation in Los Angeles where we covered the evolution of the X product, how he mastered growth by hacking and learning to "think like an adversary", and what it's like to work with Elon Musk. Enjoy. Chapters: 00:00 No Silver Bullet to Growth 00:18 The Evolution of X: From PayPal to Financial Network 01:25 A Tour of South Bay 01:56 Growing Up in South Bay: Internet Adventures 03:11 From Hacking to Growth Hacking 06:57 Joining X: The Journey and Challenges 09:14 Revolutionizing X: Growth and Product Development 15:44 The Role of a Product Head at X 29:13 Balancing Free Speech and Authenticity on X 34:58 The Future of X: AI, Links, and User Engagement 37:22 Solving Engagement Issues on X 40:42 Working with Elon Musk 50:13 Building Viral Apps: TBH and Gas 01:02:35 Consulting and Angel Investing 01:10:09 AI's Impact on App Development 01:12:49 Personal Anecdotes and Reflections
1:15:17

The one and only Nikita Bier is today's guest on Out of Office. He's X's head of product, a Lightspeed venture partner, and the world's leading expert on consumer product growth. He and I recently had a long conversation in Los Angeles where we covered the evolution of the X product, how he mastered growth by hacking and learning to "think like an adversary", and what it's like to work with Elon Musk. Enjoy. Chapters: 00:00 No Silver Bullet to Growth 00:18 The Evolution of X: From PayPal to Financial Network 01:25 A Tour of South Bay 01:56 Growing Up in South Bay: Internet Adventures 03:11 From Hacking to Growth Hacking 06:57 Joining X: The Journey and Challenges 09:14 Revolutionizing X: Growth and Product Development 15:44 The Role of a Product Head at X 29:13 Balancing Free Speech and Authenticity on X 34:58 The Future of X: AI, Links, and User Engagement 37:22 Solving Engagement Issues on X 40:42 Working with Elon Musk 50:13 Building Viral Apps: TBH and Gas 01:02:35 Consulting and Angel Investing 01:10:09 AI's Impact on App Development 01:12:49 Personal Anecdotes and Reflections

Michael Mignano

584,701 Aufrufe • vor 9 Monaten

It's brain versus AI time. Here's our full episode with Sebastian Seung. He's started a new company to reverse engineer the brain and master the intelligence created by nature with the hopes of informing the intelligence we've created with machines. Sebastian has done pioneering AI and neuroscience work and is now blending the two to make a digital brain. Mostly, he's fun to listen to. The Core Memory podcast is made by possible by the intelligent finance powerhouse Brex and the people who back the biggest ideas @e1ventures. Timestamps 00:00:00 - Intro 00:01:42 - Who is Sebastian Seung? 00:03:23 - What is a Connectome? 00:07:08 - The Connectome Winter 00:09:08 - Diamond Knives & AI 00:12:10 - When Will We Map the Human Brain? 00:18:09 - The "Brain Crystal" & Visual Neurons 00:26:31 - New Startup 00:33:55 - Simulating a Mind in Software 00:37:40 - Biology vs. Nvidia 00:44:04 - Is AI a Religious Quest? 00:50:05 - Mind Uploading & Transhumanism 00:59:26 - Brain-Computer Interfaces 01:06:41 - From Physics to Neuroscience 01:12:22 - Will Uploads Be Conscious? 01:19:37 - Neuromorphic Chips & Future Robotics
1:28:39

It's brain versus AI time. Here's our full episode with Sebastian Seung. He's started a new company to reverse engineer the brain and master the intelligence created by nature with the hopes of informing the intelligence we've created with machines. Sebastian has done pioneering AI and neuroscience work and is now blending the two to make a digital brain. Mostly, he's fun to listen to. The Core Memory podcast is made by possible by the intelligent finance powerhouse Brex and the people who back the biggest ideas @e1ventures. Timestamps 00:00:00 - Intro 00:01:42 - Who is Sebastian Seung? 00:03:23 - What is a Connectome? 00:07:08 - The Connectome Winter 00:09:08 - Diamond Knives & AI 00:12:10 - When Will We Map the Human Brain? 00:18:09 - The "Brain Crystal" & Visual Neurons 00:26:31 - New Startup 00:33:55 - Simulating a Mind in Software 00:37:40 - Biology vs. Nvidia 00:44:04 - Is AI a Religious Quest? 00:50:05 - Mind Uploading & Transhumanism 00:59:26 - Brain-Computer Interfaces 01:06:41 - From Physics to Neuroscience 01:12:22 - Will Uploads Be Conscious? 01:19:37 - Neuromorphic Chips & Future Robotics

Ashlee Vance

39,971 Aufrufe • vor 11 Monaten

Today’s guest on the Free Radicals podcast is José Luis Ricón Fernández de la Puente, head of theory Retro Biosciences and blogger Jose is a prolific blogger, covering a wide breadth of topics across economics, philosophy, progress studies, science funding, much more, and of course longevity. His works have been published by a16z, Works in Progress and Adam Smith Institute. Our conversation is wide ranging, spanning a deep dive on Retro’s work to replace and engineer microglia to rejuvenate the brain and how our cells have the ability to turn back the aging clock but choose not to. We also covered the technological stagnation and why biological engineering is the new frontier of progress, as well as philosophical topics like transhumanism and how a future of total biological control might impact our values and way of life. Be sure to follow me and Eric Dai to stay up to date on the latest news in longevity biotech! And Special thank you to NFX & omri_drory for lending us their beautiful podcasting studio! 0:00 Intro 2:49 What is aging & why cells have a tough choice to make 9:02 When cells choose to reverse aging themselves 12:43 Cellular vs Organismal Aging & the magic wand experiment 18:31 What is reprogramming 22:40 How reprogramming plays a role in DNA damage repair 25:42 Do we already know how to cure aging? FOXO3! 28:37 How to cut through the complexity of interconnected biology 32:32 Why transcription factors are so great for intervening 36:49 Does a rejuvenation program exist already in the genome 38:51 Michael Levin: from thinking in terms of genes to morphogenesis 48:14 Tech stagnation and why physics is cooked 55:03 Why doesn't the world look more futuristic 57:26 Transhumanism & asking ourselves what we want out of life 1:05:34 Do we need war for technological progress 1:09:31 Government role in science funding 1:15:06 How Jose became the Head of Theory at Retro 1:24:53 How AI might put software engineers out of a job, and push them towards biotech 1:27:28 What it takes to get a flywheel in biotech 1:29:04 Rejuvenation vs Prevention 1:34:23 Aging is the coolest hardest problem to work on 1:36:09 What does it take to cure aging 1:42:25 Delivery mechanisms for genetic therapies 1:48:53 Retro's work to replace microglia and engineer them outside the body 1:59:10 Consciousness 2:00:39 Jose's Origin Story
2:05:48

Today’s guest on the Free Radicals podcast is José Luis Ricón Fernández de la Puente, head of theory Retro Biosciences and blogger Jose is a prolific blogger, covering a wide breadth of topics across economics, philosophy, progress studies, science funding, much more, and of course longevity. His works have been published by a16z, Works in Progress and Adam Smith Institute. Our conversation is wide ranging, spanning a deep dive on Retro’s work to replace and engineer microglia to rejuvenate the brain and how our cells have the ability to turn back the aging clock but choose not to. We also covered the technological stagnation and why biological engineering is the new frontier of progress, as well as philosophical topics like transhumanism and how a future of total biological control might impact our values and way of life. Be sure to follow me and Eric Dai to stay up to date on the latest news in longevity biotech! And Special thank you to NFX & omri_drory for lending us their beautiful podcasting studio! 0:00 Intro 2:49 What is aging & why cells have a tough choice to make 9:02 When cells choose to reverse aging themselves 12:43 Cellular vs Organismal Aging & the magic wand experiment 18:31 What is reprogramming 22:40 How reprogramming plays a role in DNA damage repair 25:42 Do we already know how to cure aging? FOXO3! 28:37 How to cut through the complexity of interconnected biology 32:32 Why transcription factors are so great for intervening 36:49 Does a rejuvenation program exist already in the genome 38:51 Michael Levin: from thinking in terms of genes to morphogenesis 48:14 Tech stagnation and why physics is cooked 55:03 Why doesn't the world look more futuristic 57:26 Transhumanism & asking ourselves what we want out of life 1:05:34 Do we need war for technological progress 1:09:31 Government role in science funding 1:15:06 How Jose became the Head of Theory at Retro 1:24:53 How AI might put software engineers out of a job, and push them towards biotech 1:27:28 What it takes to get a flywheel in biotech 1:29:04 Rejuvenation vs Prevention 1:34:23 Aging is the coolest hardest problem to work on 1:36:09 What does it take to cure aging 1:42:25 Delivery mechanisms for genetic therapies 1:48:53 Retro's work to replace microglia and engineer them outside the body 1:59:10 Consciousness 2:00:39 Jose's Origin Story

Daniel Shur

13,644 Aufrufe • vor 8 Monaten