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Brain imaging using a new technique called Hierarchical Phase-Contrast Tomography or ‘HiP-CT’: h/t BrainBridger News Credits: Walsh, C.L., Tafforeau, P., Wagner, W.L. et al. #neuroscience #MedTwitter

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Hugo Chrost

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164,361 görüntüleme • 3 yıl önce •via X (Twitter)

Bilim & TeknolojiSağlık & İyilik#neuroscience#MedTwitter
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@BrainBridger A new X-ray technology allows for whole organs to be imaged down to a resolution of one micron.

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@BrainBridger Thanks for sharing! :)

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@BrainBridger Clinically when will you find it helpful?

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Benzer Videolar

HiP-CT is a revolutionary imaging technique that reveals the human body in extraordinary detail. Zoom from an entire organ down to cells and blood vessels. Here, exploring the human brain at micron-scale. [📹 Paul Tafforeau]
0:31

HiP-CT is a revolutionary imaging technique that reveals the human body in extraordinary detail. Zoom from an entire organ down to cells and blood vessels. Here, exploring the human brain at micron-scale. [📹 Paul Tafforeau]

Massimo

80,176 görüntüleme • 5 ay önce

HIP-CT JUST TURNED THE HUMAN BRAIN INTO A GOOGLE MAP This isn’t CGI. It’s not AI. It’s HiP-CT - Hierarchical Phase-Contrast Tomography - and it’s quietly breaking anatomy. One scan lets researchers zoom from a full human organ down to micron-scale detail. Blood vessels. Cellular architecture. Structural patterns you normally only see after cutting tissue apart. Except here, nothing is destroyed. The brain footage is the flex: intact hemispheres rendered so clean you can trace vascular networks like street grids. No stains. No dyes. Just synchrotron X-rays, and obscene resolution. Traditional histology gives detail but loses context. MRI keeps context but sacrifices precision. HiP-CT does both. Whole-organ truth, no trade-off. This is a new baseline for studying neurodegeneration, tumors, stroke damage, and developmental disorders. Pathology without guesswork. Anatomy without amputation. Within a decade, HiP-CT-style imaging becomes the gold standard for post-mortem research and drug validation - and forces medicine to rewrite parts of the anatomy textbooks we thought were “settled.” The body didn’t change. Our ability to see it just did. Source: Paul Tafforeau, Interesting World
0:31

HIP-CT JUST TURNED THE HUMAN BRAIN INTO A GOOGLE MAP This isn’t CGI. It’s not AI. It’s HiP-CT - Hierarchical Phase-Contrast Tomography - and it’s quietly breaking anatomy. One scan lets researchers zoom from a full human organ down to micron-scale detail. Blood vessels. Cellular architecture. Structural patterns you normally only see after cutting tissue apart. Except here, nothing is destroyed. The brain footage is the flex: intact hemispheres rendered so clean you can trace vascular networks like street grids. No stains. No dyes. Just synchrotron X-rays, and obscene resolution. Traditional histology gives detail but loses context. MRI keeps context but sacrifices precision. HiP-CT does both. Whole-organ truth, no trade-off. This is a new baseline for studying neurodegeneration, tumors, stroke damage, and developmental disorders. Pathology without guesswork. Anatomy without amputation. Within a decade, HiP-CT-style imaging becomes the gold standard for post-mortem research and drug validation - and forces medicine to rewrite parts of the anatomy textbooks we thought were “settled.” The body didn’t change. Our ability to see it just did. Source: Paul Tafforeau, Interesting World

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A beautiful animation – glimpse into brain activity. Via joshualklai #neuroscience #MedTwitter
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A beautiful animation – glimpse into brain activity. Via joshualklai #neuroscience #MedTwitter

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A CT scan technique designed for safe animal imaging
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A CT scan technique designed for safe animal imaging

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Neurons making connections with each other. Credits: Caroline Leaf #neuroscience #MedTwitter
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Neurons making connections with each other. Credits: Caroline Leaf #neuroscience #MedTwitter

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Amazing video presenting neurone making connections. Credits: Leigh Needleman #neuroscience #MedTwitter
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Amazing video presenting neurone making connections. Credits: Leigh Needleman #neuroscience #MedTwitter

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Announcing CT Foundation, a new medical imaging embedding tool that accepts a computed tomography (CT) volume as input and returns a small, information-rich numerical embedding that can be used to rapidly train models. Learn more and try it out yourself →
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Announcing CT Foundation, a new medical imaging embedding tool that accepts a computed tomography (CT) volume as input and returns a small, information-rich numerical embedding that can be used to rapidly train models. Learn more and try it out yourself →

Google AI

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From the brain to every little synapse. An incredible video by allen institute #neuroscience #MedTwitter
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From the brain to every little synapse. An incredible video by allen institute #neuroscience #MedTwitter

Hugo Chrost

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AR helps surgeons plan complex brain surgeries
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AR helps surgeons plan complex brain surgeries

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Introducing Brain Credits 🧠 Representing a new approach to decentralized AI ownership and participation, Brain Credits function as digital tokens, redeemable for full or fractional ownership of a Brain. To obtain Brain Credits, burn $PepeCoin. (Pepecoin) 🔥 9.30.24 🔥
2:11

Introducing Brain Credits 🧠 Representing a new approach to decentralized AI ownership and participation, Brain Credits function as digital tokens, redeemable for full or fractional ownership of a Brain. To obtain Brain Credits, burn $PepeCoin. (Pepecoin) 🔥 9.30.24 🔥

BasedAI

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Changing eye colour using a technique called keratopigmentation
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Changing eye colour using a technique called keratopigmentation

Science girl

50,500 görüntüleme • 11 ay önce

H I P for the hip P O P O for the hippopo and T A M U S for the hippopotamus 🦛 HIPPOPOTAMUS 🦛!!! 😂🤣😂 #BBNaija #bbnaija2024 #BBN
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H I P for the hip P O P O for the hippopo and T A M U S for the hippopotamus 🦛 HIPPOPOTAMUS 🦛!!! 😂🤣😂 #BBNaija #bbnaija2024 #BBN

🪝💜Cynthia🎙️🌶️☄️🦁🛡️

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From 3D imaging to therapy Using our DISCO tissue clearing and whole organ 3D imaging platform, we revealed skull to meninges microchannels connecting calvarial bone marrow with the brain borders in mice (Cai...Ertürk, Nature Neuroscience,2018, We then extended this biology to humans, discovering distinct skull bone marrow programs and structural skull meninges connections in health and neurological disease (Kolabas...Ertürk, Cell, 2023). Now, a new study reports a first therapeutic application of this route: intracalvariosseous (calvarial) injection of drug loaded albumin nanoparticles to “hijack” calvarial immune cells, which then migrate via skull meninges microchannels to CNS lesions, bypassing the blood brain barrier and improving outcomes in stroke models, with encouraging clinical feasibility data (Gao et al., Cell, 2026) We are proud that DISCO enabled biology that is now turning into concrete therapeutic strategies for devastating neurological diseases. More to come. #DISCO #TissueClearing #Neuroimmunology #Stroke #Nanomedicine #DrugDelivery #BBB #CNS Refs (for linking in comments): Cai et al. Nat Neuroscience, Kolabas et al. Cell 2023, the video from Gao et al. Cell 2026 (online Jan 16, 2026).
0:29

From 3D imaging to therapy Using our DISCO tissue clearing and whole organ 3D imaging platform, we revealed skull to meninges microchannels connecting calvarial bone marrow with the brain borders in mice (Cai...Ertürk, Nature Neuroscience,2018, We then extended this biology to humans, discovering distinct skull bone marrow programs and structural skull meninges connections in health and neurological disease (Kolabas...Ertürk, Cell, 2023). Now, a new study reports a first therapeutic application of this route: intracalvariosseous (calvarial) injection of drug loaded albumin nanoparticles to “hijack” calvarial immune cells, which then migrate via skull meninges microchannels to CNS lesions, bypassing the blood brain barrier and improving outcomes in stroke models, with encouraging clinical feasibility data (Gao et al., Cell, 2026) We are proud that DISCO enabled biology that is now turning into concrete therapeutic strategies for devastating neurological diseases. More to come. #DISCO #TissueClearing #Neuroimmunology #Stroke #Nanomedicine #DrugDelivery #BBB #CNS Refs (for linking in comments): Cai et al. Nat Neuroscience, Kolabas et al. Cell 2023, the video from Gao et al. Cell 2026 (online Jan 16, 2026).

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P A T H E T I C goon!
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P A T H E T I C goon!

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P H A N T ✺ M
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This #Robotic Guidewire Could Help Clear Blood Clots In the Brain! by Massachusetts Institute of Technology (MIT) Digital Doctor h/t Ronald van Loon #Digital #Tech #Innovation #Startup #CXO #IT #MedTwitter
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This #Robotic Guidewire Could Help Clear Blood Clots In the Brain! by Massachusetts Institute of Technology (MIT) Digital Doctor h/t Ronald van Loon #Digital #Tech #Innovation #Startup #CXO #IT #MedTwitter

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A great way to study brain anatomy: #neuroscience
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A great way to study brain anatomy: #neuroscience

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Together with UC Berkeley we are announcing the laser phase plate - a breakthrough in atomic resolution imaging. This is the brightest continuous wave laser in the world, 100 million times the intensity of the surface of the sun. Phase contrast plays an important role in microscopy, but it was thought close to impossible for electron microscopy, where it would require interfering with an electron beam. Holger Mueller and Robert Glaeser proposed exactly this using a standing wave laser. It has taken over 15 years to make this a reality. Biohub partnered with UC Berkeley and Mueller to support this work and to engineer and build the technology. Contrast has been the critical barrier to achieving atomic resolution imaging of the cell. In cryo-electron tomography, a cellular imaging technology that uses electron microscopy, the low contrast makes it impossible to resolve anything but the largest proteins within their cellular context. The laser phase plate removes that barrier. With advances in AI this breakthrough in contrast will start to open up a new frontier in structural biology, that will allow us to see the molecular machines of the cell, and how they assemble into far more complex and dynamic systems, and understand how they work.
0:46

Together with UC Berkeley we are announcing the laser phase plate - a breakthrough in atomic resolution imaging. This is the brightest continuous wave laser in the world, 100 million times the intensity of the surface of the sun. Phase contrast plays an important role in microscopy, but it was thought close to impossible for electron microscopy, where it would require interfering with an electron beam. Holger Mueller and Robert Glaeser proposed exactly this using a standing wave laser. It has taken over 15 years to make this a reality. Biohub partnered with UC Berkeley and Mueller to support this work and to engineer and build the technology. Contrast has been the critical barrier to achieving atomic resolution imaging of the cell. In cryo-electron tomography, a cellular imaging technology that uses electron microscopy, the low contrast makes it impossible to resolve anything but the largest proteins within their cellular context. The laser phase plate removes that barrier. With advances in AI this breakthrough in contrast will start to open up a new frontier in structural biology, that will allow us to see the molecular machines of the cell, and how they assemble into far more complex and dynamic systems, and understand how they work.

Alex Rives

635,872 görüntüleme • 7 gün önce

{ G.O.A.T } 🔥 T H A L A P A T H Y 🌠✨🙏 #Varisu @ActorVijay 🥺🙏
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{ G.O.A.T } 🔥 T H A L A P A T H Y 🌠✨🙏 #Varisu @ActorVijay 🥺🙏

TVK Magi 🇪🇦 🌟💫✨

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Types of different gait patterns we see in #neuroscience #neurosurgery #healthcare #MedEd #MedTwitter
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Types of different gait patterns we see in #neuroscience #neurosurgery #healthcare #MedEd #MedTwitter

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