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In 2025, the AgentFlayer exploit highlighted a new category of risk in AI systems. It was not a traditional breach involving stolen credentials or broken encryption. Instead, it demonstrated how an autonomous AI agent could be manipulated into executing unintended actions by processing malicious instructions embedded inside content it automatically processes. The incident did not expose a flaw in one specific integration. It revealed a structural weakness in how many modern AI agents are built. Today’s agents are no longer passive language models. They read documents automatically, scan emails, connect to SaaS tools, access cloud storage, and execute actions across multiple systems. To be useful, they are granted meaningful permissions. That capability creates value, but it also expands the attack surface. Most agent environments operate in a trusted, plaintext execution model. Data is encrypted at rest and in transit, but it is typically decrypted during inference so the model can process it. That runtime visibility is where potential risk lies. In a zero-click scenario like AgentFlayer, an attacker can embed hidden instructions inside a document that the AI processes automatically. Because the agent may have access to connected systems such as Google Drive, Slack, or GitHub, it can potentially be influenced to retrieve sensitive information or perform unintended actions. The user does not need to click a malicious link or approve a suspicious request. Therefore, the core issue is that during execution, the system may have access to sensitive data and broad privileges, meaning whoever controls the execution environment ultimately controls access to that data. Now consider a different architectural approach. If a system is designed so that data remains protected during execution, the risk profile changes. On Nesa, privacy is enforced at the execution layer through Equivariant Encryption. Computation can occur on encrypted data, reducing the visibility surface during runtime. Sensitive inputs and models do not need to be exposed in plain text to infrastructure operators for inference to occur. This does not eliminate prompt injection, logic manipulation, or tool misuse. Encryption alone cannot prevent an agent from being instructed to take an unintended action if it has been granted that permission. What it does do is materially reduce confidentiality risk. By limiting access to readable sensitive data during execution and reducing unilateral visibility at the infrastructure layer, the potential blast radius of a successful manipulation attempt is constrained. As AI agents become more autonomous and embedded into enterprise workflows, security must move deeper into architecture. The goal is not to claim invulnerability. It is to reduce trust concentration and contain systemic exposure when failures occur. AgentFlayer was not simply a one-off exploit. It was a reminder that in autonomous systems, execution-layer design determines how risk propagates.

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To replace animal testing with AI, we need MASSIVE human datasets. Today, we're thrilled to share Axiom's new data exploration tool, providing the ability to visually explore the world's largest primary human liver toxicity dataset. Built with Axiom's proprietary wetlab protocols, our dataset includes detailed liver toxicity profiles for over 100,000 distinct molecules. The key to this dataset is our ability to do high-throughput, multiplexed high-content screening with primary human liver cells. Traditionally, toxicity assays either sacrifice throughput or sacrifice biological relevance (using easy-to-grow immortalized cell lines instead of real human cells). We managed to combine throughput, physiological relevance, and multiplexing in one platform. The assays run in a high throughput format using automation, meaning thousands of compound-dose conditions can be tested in one experiment. We achieved this using pooled primary human hepatocytes, which are often fragile and expensive. By systemizing our automation and quality control processes, we were able to run over 120+ batches on the same donor pool with incredible reproducibility and consistency. We did this while integrating many readouts per well, whereas many existing toxicity assays only do a single readout. Our multiplexed approach provides far more data per experiment enabling us to measure 10-20 different toxicity phenotypes such as apoptosis, necrosis, mitochondrial fission, endoplasmic reticulum stress, stress granule formation, microtubules, and more all from a single well on a 384-well plate! The combination of scale, high content information, and data quality is exactly what is needed to train highly accurate AI models in biology. If you're interested, please explore the dataset in the comments below and let me know if you want to chat about the details!

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“Just vote yes and we’re our own country.” Cool. Here’s the actual to-do list you’d have to negotiate first You’d have to settle: → Share of the national debt → Split of federal assets → Embassies & foreign property → Crown corporations → Federal pensions → Keep the loonie? Make a new currency? → Central bank access → Deposit insurance & banking rules → Foreign reserves → Citizenship & dual nationality → Passports → Free movement across the new border → Exact land borders → Maritime borders → Indigenous treaty rights (these don’t just transfer) → Whether Indigenous nations can stay with Canada → A whole new trade deal → Status under USMCA, CETA, CPTPP (not automatic) → Tariffs, customs, standards → Professional licensing across the border → UN membership (you re-apply) → Hundreds of treaties, renegotiated → Diplomatic recognition → NATO & NORAD membership → Splitting the armed forces → Military bases & equipment → Intelligence sharing (Five Eyes access) → Border security & the RCMP → Coast guard & airspace → CPP & pension portability → Old Age Security → Health transfers → Employment insurance → Pipelines & the power grid → Railways, highways, seaways → Shared rivers & water → Telecom & spectrum → Air traffic control → Tax systems & taxpayer data → Courts & appeals (no more Supreme Court of Canada) → Every federal regulator: food, drugs, aviation, broadcasting → Thousands of federal employees → …and what happens if talks just collapse 50%+1 creates a duty to negotiate — not a guarantee you get what you want, or that a deal even happens. “Independence” is the easy word. That list is the actual job.

Dimitris Soudas 🇨🇦⚜️🇬🇷☦️ 13.12.1943

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50 websites that can turn a “5-minute break” into hours of exploring 🌐 1. — Discover fascinating websites at random 2. — Search the old-school web 3. — Find hidden internet gems 4. — Human-curated useful tools 5. — Random weird & wonderful websites 6. — Explore live radio around the world 7. — Drive through cities with local radio 8. — Geography games with real locations 9. — Guess cities from walking videos 10. — Explore the world through clues 11. — Street-level imagery from around the world 12. — Turn historical maps into interactive maps 13. — Browse historical maps 14. — Explore detailed interactive game maps 15. — Watch global winds & weather 16. — Visualize weather across the planet 17. — Explore Earth’s atmosphere in motion 18. — Travel through music by country & decade 19. — Discover music through connections 20. — Explore thousands of music genres 21. — Explore concert setlists from around the world 22. — Discover live music history 23. — Explore movies through people & lists 24. — Find movies by describing them 25. — Explore movie frames 26. — Search movies by visual composition 27. — Travel through the old internet 28. — Explore a massive web archive 29. — Explore Australia’s digital archives 30. — Search New Zealand’s cultural collections 31. — Explore Europe’s digital heritage 32. — Explore millions of digital objects 33. — Explore design history 34. — Explore American art collections 35. — Explore historic biology books 36. — Explore biodiversity data 37. — Explore species data worldwide 38. — Identify & explore species around you 39. — Watch ships move around the world 40. — Track flights worldwide 41. — Explore detailed satellite imagery 42. — Explore global population data 43. — Explore data about countries & cities 44. — Play with global development data 45. — Explore computational answers 46. — Jump between radio stations worldwide 47. — One click into internet chaos 48. — Find a random person pointing at your cursor 49. — Look through windows around the world 50. — Weird, clever & addictive interactive experiments The internet is still full of places most people never discover. 🔖 Save this list. following You’ll definitely come back to it. Follow Amelia hazel for more hidden websites, useful tools & AI discoveries.

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Wall St Engine

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50 completely new websites that can turn a quick visit into hours of exploring Earth milkey way galaxy experience 🌍👇 1. — Explore Mars in 3D 2. — Where your city was millions of years ago 3. — Timeline from Big Bang to now 4. — Feel the true scale of time 5. — Fly through 100,000 stars 6. — Music by any country + decade 7. — Explore the map of music genres 8. — Drive through cities with local radio 9. — Infinite zooming artwork 10. — Create silk-like digital art 11. — Powerful ambient sound generator 12. — Mix your own soundscapes 13. — Make music by pressing keys 14. — People pointing at your cursor 15. — Fake hacker terminal 16. — Find the invisible cow 17. — Zoom into koalas forever 18. — Ultra high-res satellite imagery 19. — Free Earth observation tool 20. — Live satellite & ISS tracker 21. — Real-time space weather 22. — Solar data & aurora forecasts 23. — Huge free space photo archive 24. — Ancient maps, atlases & globes 25. — Interactive map of 2400+ castles 26. — Ancient Roman roads planner 27. — Historical maps collection 28. — Possible future timelines 29. — Visual predictions of Earth 2050 30. — Interactive population history 31. — Interactive history timeline 32. — Deep interactive star map 33. — Online sky atlas 34. — ISS & satellite passes 35. — 3D objects in Earth orbit 36. — Live satellite positions 37. — Track Earth-imaging satellites 38. — Cozy lofi spaces 39. — Historical transit maps 40. — Collaborative annotated world map 41. Drop into random places 42. — Pure random Street View 43. — Create & explore custom maps 44. — Geospatial data explorer 45. — Interactive global maps 46. — Climate & weather data tools 47. — Sea level rise explorer 48. — Ancient Earth viewer 49. — Fresh curated cool websites 50. — Deep timeline experience The internet still has so many hidden corners. 🔖 Bookmark this for later. Follow for more rare finds. 🚀 Justin Brave💡

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