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I interviewed Aubrey de Grey on why neither billionaires nor AI will solve aging. And why a single mouse breakthrough could be the ChatGPT moment for longevity. 0:00 - Longevity Field 20 Years On 08:58 - Are Billionaires Getting It Wrong? 17:13 - Bryan Johnson vs Peter Thiel 23:42... show more

Mgoes (bio/acc 🤖💉)

36,707 subscribers

45,346 次观看 • 5 个月前 •via X (Twitter)

健康养生科学技术

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Mgoes (bio/acc 🤖💉)

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12,064 次观看 • 1 年前

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Raoul Pal

166,795 次观看 • 1 年前

Today I am launching the Free Radicals podcast with Eric Dai . Every Tuesday, we’ll be releasing long form conversations with the visionaries giving humanity control over biology and working to dramatically extend human lifespan. We’re thrilled to host Celine Halioua, Founder + CEO Loyal, for our inaugural episode. Celine is building the world’s first lifespan extension drugs for dogs. Follow me, Eric Dai and Free Radicals for new episodes every Tuesday. 00:00:00 - Intro 00:01:51 - Celine’s background 00:05:00 - Dropping out of academia 00:07:50 - Finding ways to increase free will 00:09:36 - How to align financial incentives with longevity 00:14:52 - Longevity drugs should be boring 00:21:24 - Celine’s leadership style 00:24:08 - Advice on fundraising and constructing feedback loops 00:26:52 - Loyal’s fundraising history 00:27:57 - Building for Zero Billion Dollar Markets 00:29:11 - How to succeed in biotech 00:30:21 - How to find blockbuster opportunities 00:33:25 - How to create a gold rush in longevity 00:35:25 - The problem with the aging field 00:39:32 - How to identify signal from noise 00:41:54 - AI applications to biology 00:45:15 - Importance of naiveté 00:47:24 - FREE RADICALS

Today I am launching the Free Radicals podcast with Eric Dai . Every Tuesday, we’ll be releasing long form conversations with the visionaries giving humanity control over biology and working to dramatically extend human lifespan. We’re thrilled to host Celine Halioua, Founder + CEO Loyal, for our inaugural episode. Celine is building the world’s first lifespan extension drugs for dogs. Follow me, Eric Dai and Free Radicals for new episodes every Tuesday. 00:00:00 - Intro 00:01:51 - Celine’s background 00:05:00 - Dropping out of academia 00:07:50 - Finding ways to increase free will 00:09:36 - How to align financial incentives with longevity 00:14:52 - Longevity drugs should be boring 00:21:24 - Celine’s leadership style 00:24:08 - Advice on fundraising and constructing feedback loops 00:26:52 - Loyal’s fundraising history 00:27:57 - Building for Zero Billion Dollar Markets 00:29:11 - How to succeed in biotech 00:30:21 - How to find blockbuster opportunities 00:33:25 - How to create a gold rush in longevity 00:35:25 - The problem with the aging field 00:39:32 - How to identify signal from noise 00:41:54 - AI applications to biology 00:45:15 - Importance of naiveté 00:47:24 - FREE RADICALS

Daniel Shur

29,403 次观看 • 7 个月前

New Limit just raised $435 million. This is, in part, because they've had a massive breakthrough on reversing the age of the liver with their new brand of genetic reprogramming drugs. For the first time, NewLimit's co-founder and president Jacob Kimmel details the company's breakthrough here. We also get into the longevity and bio-tech fields more broadly to explain where aging science and AI are heading. If nothing else, come to see some mice get drunk. The Core Memory podcast is available wherever you pod, and I'll put the YouTube link down below in the replies. Our show is sponsored by Brex and SendCutSend. They are both wise and benevolent. Timestamps 0:00 Intro 3:50 What Is Epigenetic Reprogramming? 7:16 Growing a Whole Animal From One Old Cell 13:06 Meet Ambrosia, the AI Hunting for Youth 22:44 $435 Million and the Race to Human Trials 29:26 The Drunk Mice That Skip the Hangover 36:48 Inside the First Human Trial 43:14 Will There Ever Be a Hangover Pen? 49:39 Beyond the Liver: The Delivery Problem 1:03:27 Answering the Skeptics 1:12:42 Will OpenAI Become a Drug Company? 1:23:53 The Health Story Bigger Than AI? 1:35:00 How Far Behind Is the US vs China? 1:53:10 Can We Build Computers From Neurons?

Ashlee Vance

93,172 次观看 • 1 个月前

Is there a Christian revival going on in America? Cliffe Knechtle would know. He’s been preaching on college campuses for 45 years. (0:00) Moral Relativism Is Running Rampant (8:23) The Tragedy of Transgenderism (17:54) Protestantism vs. Catholicism vs. Orthodoxy (25:12) Cliffe’s Greatest Challenge (28:12) The Importance of Self-Discipline (29:43) Cliffe’s Biggest Debates (34:54) Why Is the Old Testament So Violent? (44:49) The Emotional Fragility of Young America (48:44) Why Secularists Hate Christianity (53:52) The Demonic Forces at Work In the World (56:05) Judas, Pharaoh, and Free Will (1:03:03) Are People Inherently Good? (1:07:28) Cliffe’s Thoughts on Gay Marriage (1:11:34) Cliffe’s Response to Abortion (1:19:15) The Dangers of Self-Righteousness (1:27:21) Who Really Are God’s Chosen People? (1:34:18) The Continuous Rise of Christian Persecution (1:37:58) Is Cliffe Ever Worried for His Safety? (1:38:49) More and More People Are Converting to Christianity (1:39:48) Is Divorce a Sin? (1:41:36) Drugs and Alcoholism (1:45:28) Is Cliffe Hopeful for America’s Future? Includes Paid Partnerships.

Is there a Christian revival going on in America? Cliffe Knechtle would know. He’s been preaching on college campuses for 45 years. (0:00) Moral Relativism Is Running Rampant (8:23) The Tragedy of Transgenderism (17:54) Protestantism vs. Catholicism vs. Orthodoxy (25:12) Cliffe’s Greatest Challenge (28:12) The Importance of Self-Discipline (29:43) Cliffe’s Biggest Debates (34:54) Why Is the Old Testament So Violent? (44:49) The Emotional Fragility of Young America (48:44) Why Secularists Hate Christianity (53:52) The Demonic Forces at Work In the World (56:05) Judas, Pharaoh, and Free Will (1:03:03) Are People Inherently Good? (1:07:28) Cliffe’s Thoughts on Gay Marriage (1:11:34) Cliffe’s Response to Abortion (1:19:15) The Dangers of Self-Righteousness (1:27:21) Who Really Are God’s Chosen People? (1:34:18) The Continuous Rise of Christian Persecution (1:37:58) Is Cliffe Ever Worried for His Safety? (1:38:49) More and More People Are Converting to Christianity (1:39:48) Is Divorce a Sin? (1:41:36) Drugs and Alcoholism (1:45:28) Is Cliffe Hopeful for America’s Future? Includes Paid Partnerships.

Tucker Carlson

2,725,017 次观看 • 10 个月前

I spoke with Jordi Visser this week to break down: - AI mid-cycle slowdown - $90 trillion AI infrastructure buildout - memory and Micron's role in AI bottleneck - Fed under Warsh - what rate cuts could mean for markets - why bitcoin is positioned to be the best performing assets once the negatives of AI start to show up YouTube: Apple: Spotify: TIMESTAMPS: 0:00 - Intro 1:20 - Has bitcoin bottomed? 6:03 - Bitcoin vs the Mag 7: is the correlation breaking? 9:00 - Sam Altman, OpenAI & the government getting involved 11:11 - American open source vs Chinese AI models 14:28 - AI compute demand & the infrastructure buildout 20:37 - AI slowdown: how bad, how long? 22:44 - Where do markets go from here? 27:30 - AI agents in the workplace & security risk 34:50 - Memory, Micron & the AI bottleneck 39:53 - The next 10-20 years: robots, AI & society 44:18 - The Fed, rate cuts & inflation's impact on AI 49:55 - Why bitcoin wins in the end

I spoke with Jordi Visser this week to break down: - AI mid-cycle slowdown - $90 trillion AI infrastructure buildout - memory and Micron's role in AI bottleneck - Fed under Warsh - what rate cuts could mean for markets - why bitcoin is positioned to be the best performing assets once the negatives of AI start to show up YouTube: Apple: Spotify: TIMESTAMPS: 0:00 - Intro 1:20 - Has bitcoin bottomed? 6:03 - Bitcoin vs the Mag 7: is the correlation breaking? 9:00 - Sam Altman, OpenAI & the government getting involved 11:11 - American open source vs Chinese AI models 14:28 - AI compute demand & the infrastructure buildout 20:37 - AI slowdown: how bad, how long? 22:44 - Where do markets go from here? 27:30 - AI agents in the workplace & security risk 34:50 - Memory, Micron & the AI bottleneck 39:53 - The next 10-20 years: robots, AI & society 44:18 - The Fed, rate cuts & inflation's impact on AI 49:55 - Why bitcoin wins in the end

Anthony Pompliano 🌪

64,370 次观看 • 9 天前

LIVE NOW - The Holy Grail of Crypto Privacy: Encrypted Ethereum, FHE & Living Forever Ethereum is transparent by design, and that’s a problem if you don’t want your entire financial life on display. Rand , co-founder of Zama, joins us to explain how fully homomorphic encryption (FHE) can turn Ethereum into an encrypted, confidential blockchain where contracts stay composable and UX feels exactly the same. -------------- TIMESTAMPS 0:00 Intro 0:24 Why Are Blockchains Public? 9:11 Privacy vs Confidentiality 11:13 Zama: Privacy on Ethereum 15:05 Fully Homomorphic Encryption (FHE) 19:34 Multi-Party Computation (MPC) 23:50 FHE vs ZK 37:25 FHE Critiques 40:08 Nation State Attacks 45:58 Combining ZK & FHE 49:20 Privacy Season 51:39 Compliance 1:00:18 Zama 1:04:03 Confidential Tokens 1:08:12 How it Works 1:11:30 Zama Token & Protocol 1:14:09 Privacy Competitors 1:17:36 Fhenix 1:19:46 Rand’s Background 1:23:07 AI Privacy 1:26:42 Longevity 1:33:01 Crypto & Privacy in 2026 1:33:33 Closing & Disclaimers

LIVE NOW - The Holy Grail of Crypto Privacy: Encrypted Ethereum, FHE & Living Forever Ethereum is transparent by design, and that’s a problem if you don’t want your entire financial life on display. Rand , co-founder of Zama, joins us to explain how fully homomorphic encryption (FHE) can turn Ethereum into an encrypted, confidential blockchain where contracts stay composable and UX feels exactly the same. -------------- TIMESTAMPS 0:00 Intro 0:24 Why Are Blockchains Public? 9:11 Privacy vs Confidentiality 11:13 Zama: Privacy on Ethereum 15:05 Fully Homomorphic Encryption (FHE) 19:34 Multi-Party Computation (MPC) 23:50 FHE vs ZK 37:25 FHE Critiques 40:08 Nation State Attacks 45:58 Combining ZK & FHE 49:20 Privacy Season 51:39 Compliance 1:00:18 Zama 1:04:03 Confidential Tokens 1:08:12 How it Works 1:11:30 Zama Token & Protocol 1:14:09 Privacy Competitors 1:17:36 Fhenix 1:19:46 Rand’s Background 1:23:07 AI Privacy 1:26:42 Longevity 1:33:01 Crypto & Privacy in 2026 1:33:33 Closing & Disclaimers

Bankless

121,302 次观看 • 7 个月前

Here's my conversation with Charan Ranganath, psychologist & neuroscientist at UC Davis, specializing in human memory. We talk about memory, imagination, deja vu, false memories, why we remember, why we forget, and a lot of other fascinating mysteries about the human mind. It's here on X in full, and is up on YouTube, Spotify, and everywhere else. Links in comment. Timestamps: 0:00 - Introduction 1:03 - Experiencing self vs remembering self 14:44 - Creating memories 24:16 - Why we forget 31:53 - Training memory 42:22 - Memory hacks 54:10 - Imagination vs memory 1:03:29 - Memory competitions 1:13:18 - Science of memory 1:28:33 - Discoveries 1:39:37 - Deja vu 1:44:54 - False memories 2:04:59 - False confessions 2:08:45 - Heartbreak 2:16:19 - Nature of time 2:24:00 - Brain–computer interface (BCI) 2:38:04 - AI and memory 2:48:18 - ADHD 2:55:15 - Music 3:05:00 - Human mind

Here's my conversation with Charan Ranganath, psychologist & neuroscientist at UC Davis, specializing in human memory. We talk about memory, imagination, deja vu, false memories, why we remember, why we forget, and a lot of other fascinating mysteries about the human mind. It's here on X in full, and is up on YouTube, Spotify, and everywhere else. Links in comment. Timestamps: 0:00 - Introduction 1:03 - Experiencing self vs remembering self 14:44 - Creating memories 24:16 - Why we forget 31:53 - Training memory 42:22 - Memory hacks 54:10 - Imagination vs memory 1:03:29 - Memory competitions 1:13:18 - Science of memory 1:28:33 - Discoveries 1:39:37 - Deja vu 1:44:54 - False memories 2:04:59 - False confessions 2:08:45 - Heartbreak 2:16:19 - Nature of time 2:24:00 - Brain–computer interface (BCI) 2:38:04 - AI and memory 2:48:18 - ADHD 2:55:15 - Music 3:05:00 - Human mind

Lex Fridman

294,521 次观看 • 2 年前

Ex-DeepMind researcher Misha Laskin on building superintelligence, coding as a shortcut, reinforcement learning, launching Reflection AI's first product, Asimov, and competing with the big AI labs 00:00 - Intro 01:42 - Reflection AI: Company Origins and Mission 04:14 - Making Superintelligence Concrete 06:04 - ASI vs. AGI: Why the Goalposts Moved 07:55 - Organizational Superintelligence as an Oracle 12:05 - Coding as Shortcut: Hands, Legs & Brain for AI 20:55 - Capturing Tribal Knowledge in Organizations 26:31 - Introducing Asimov: Deep Research for Code 28:44 - Team-Wide Memory 33:07 - Multi-Agent Design 34:48 - Data Retrieval and Integration in Asimov 39:41 - Reinforcement Learning in Asimov 41:04 - Misha's Journey: From Physics to AI 42:06 - Growing Up in a Science-Driven Desert Town 53:03 - Building General Agents at DeepMind 56:57 - Founding Reflection AI After DeepMind 58:54 - Product vs tech in AI 1:02:22 - The State of Autonomous Coding Agents 1:04:26 - What's Next for Reflection AI

Ex-DeepMind researcher Misha Laskin on building superintelligence, coding as a shortcut, reinforcement learning, launching Reflection AI's first product, Asimov, and competing with the big AI labs 00:00 - Intro 01:42 - Reflection AI: Company Origins and Mission 04:14 - Making Superintelligence Concrete 06:04 - ASI vs. AGI: Why the Goalposts Moved 07:55 - Organizational Superintelligence as an Oracle 12:05 - Coding as Shortcut: Hands, Legs & Brain for AI 20:55 - Capturing Tribal Knowledge in Organizations 26:31 - Introducing Asimov: Deep Research for Code 28:44 - Team-Wide Memory 33:07 - Multi-Agent Design 34:48 - Data Retrieval and Integration in Asimov 39:41 - Reinforcement Learning in Asimov 41:04 - Misha's Journey: From Physics to AI 42:06 - Growing Up in a Science-Driven Desert Town 53:03 - Building General Agents at DeepMind 56:57 - Founding Reflection AI After DeepMind 58:54 - Product vs tech in AI 1:02:22 - The State of Autonomous Coding Agents 1:04:26 - What's Next for Reflection AI

Matt Turck

11,971 次观看 • 1 年前

Here's my conversation with the founding team of Cursor, a popular code editor (based on VSCode) that specializes in AI-assisted programming. This is a super technical conversation that is bigger than just about one code editor. It's about the future of programming and, in general, the future of human-AI collaboration. It's here on X in full, and is up on everywhere else. Timestamps: 0:00 - Introduction 0:59 - Code editor basics 3:09 - GitHub Copilot 10:27 - Cursor 16:54 - Cursor Tab 23:08 - Code diff 31:20 - ML details 36:54 - GPT vs Claude 43:28 - Prompt engineering 50:54 - AI agents 1:04:51 - Running code in background 1:09:31 - Debugging 1:14:58 - Dangerous code 1:26:09 - Branching file systems 1:29:20 - Scaling challenges 1:43:32 - Context 1:48:39 - OpenAI o1 2:00:01 - Synthetic data 2:03:48 - RLHF vs RLAIF 2:05:34 - Fields Medal for AI 2:08:17 - Scaling laws 2:17:06 - The future of programming

Here's my conversation with the founding team of Cursor, a popular code editor (based on VSCode) that specializes in AI-assisted programming. This is a super technical conversation that is bigger than just about one code editor. It's about the future of programming and, in general, the future of human-AI collaboration. It's here on X in full, and is up on everywhere else. Timestamps: 0:00 - Introduction 0:59 - Code editor basics 3:09 - GitHub Copilot 10:27 - Cursor 16:54 - Cursor Tab 23:08 - Code diff 31:20 - ML details 36:54 - GPT vs Claude 43:28 - Prompt engineering 50:54 - AI agents 1:04:51 - Running code in background 1:09:31 - Debugging 1:14:58 - Dangerous code 1:26:09 - Branching file systems 1:29:20 - Scaling challenges 1:43:32 - Context 1:48:39 - OpenAI o1 2:00:01 - Synthetic data 2:03:48 - RLHF vs RLAIF 2:05:34 - Fields Medal for AI 2:08:17 - Scaling laws 2:17:06 - The future of programming

Lex Fridman

1,260,683 次观看 • 1 年前