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If serotonin plays a crucial role in fetal development (which it does) & if SSRIs disrupt the serotonin system (which they do) then the SSRIs must alter fetal development - and the public should be warned. This point was not disputed at yesterday's panel.

Adam Urato, MD

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43,657 views • 1 year ago •via X (Twitter)

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ICYMI: Highlights from yesterday’s expert panel on SSRIs and pregnancy. “Serotonin may play a crucial role in the development of the organs of a baby in utero, specifically the heart, brain, and even the gut. SSRIs have also been implicated in different studies to be involved in postpartum hemorrhage, pulmonary hypertension, and cognitive downstream effects in the baby.”

ICYMI: Highlights from yesterday’s expert panel on SSRIs and pregnancy. “Serotonin may play a crucial role in the development of the organs of a baby in utero, specifically the heart, brain, and even the gut. SSRIs have also been implicated in different studies to be involved in postpartum hemorrhage, pulmonary hypertension, and cognitive downstream effects in the baby.”

U.S. FDA

28,036 views • 1 year ago

Gary Brecka just flipped everything we’ve been told about depression: We’re told low serotonin causes depression, so we take SSRIs to “fix” it. But Brecka says SSRIs don’t raise serotonin — they just ration what little you have. 90% of your serotonin is made in your gut from tryptophan. If your gut or methylation is off, your brain never gets what it needs. Research shows that gut bacteria play a key role in serotonin production — up to 90% of the body’s supply is synthesized in the intestines, not the brain. He argues many mood disorders (depression, anxiety, ADHD, ruminating thoughts) may actually start in the gut — not the brain. This shifts the conversation from lifelong meds to fixing root causes. Real hope for people who’ve been struggling. This one really made sense to me. I’ve seen how gut issues can tank mood and energy. The idea that we might be able to support natural serotonin production feels way more empowering. What do you think — could gut health and methylation be a bigger piece of mood disorders than we’ve been told?

Gary Brecka just flipped everything we’ve been told about depression: We’re told low serotonin causes depression, so we take SSRIs to “fix” it. But Brecka says SSRIs don’t raise serotonin — they just ration what little you have. 90% of your serotonin is made in your gut from tryptophan. If your gut or methylation is off, your brain never gets what it needs. Research shows that gut bacteria play a key role in serotonin production — up to 90% of the body’s supply is synthesized in the intestines, not the brain. He argues many mood disorders (depression, anxiety, ADHD, ruminating thoughts) may actually start in the gut — not the brain. This shifts the conversation from lifelong meds to fixing root causes. Real hope for people who’ve been struggling. This one really made sense to me. I’ve seen how gut issues can tank mood and energy. The idea that we might be able to support natural serotonin production feels way more empowering. What do you think — could gut health and methylation be a bigger piece of mood disorders than we’ve been told?

Camus

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🔥 MAHA is about to go after SSRIs FDA chief Dr. Marty Makary: “Some observational studies have suggested SSRIs taken during pregnancy may increase the risk of birth defects, miscarriage, and neurological and behavioral problems later in childhood.” “At least one SSRI has been linked to heart defects in babies when exposed in the first trimester.” “This birth defect may be due to the fact that serotonin may play a critical role in the development of the heart as well as the brain and the gut of babies in utero.” “Next Monday, July 21st at 10am, we will be gathering a diverse group of experts to have a public discussion that you can watch about the current state of science regarding the impact of SSRIs in pregnancy.” Marty Makary MD, MPH Dr. Marty Makary

🔥 MAHA is about to go after SSRIs FDA chief Dr. Marty Makary: “Some observational studies have suggested SSRIs taken during pregnancy may increase the risk of birth defects, miscarriage, and neurological and behavioral problems later in childhood.” “At least one SSRI has been linked to heart defects in babies when exposed in the first trimester.” “This birth defect may be due to the fact that serotonin may play a critical role in the development of the heart as well as the brain and the gut of babies in utero.” “Next Monday, July 21st at 10am, we will be gathering a diverse group of experts to have a public discussion that you can watch about the current state of science regarding the impact of SSRIs in pregnancy.” Marty Makary MD, MPH Dr. Marty Makary

Holden Culotta

34,490 views • 1 year ago

New research links maternal diet to ADHD & autism risk. A Western diet during pregnancy increases ADHD risk by 66% and autism risk by 122%. Findings suggest prenatal nutrition plays a critical role in fetal brain development. Should dietary guidelines be reconsidered?

New research links maternal diet to ADHD & autism risk. A Western diet during pregnancy increases ADHD risk by 66% and autism risk by 122%. Findings suggest prenatal nutrition plays a critical role in fetal brain development. Should dietary guidelines be reconsidered?

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It is because of the All Bodo Students Union (ABSU), which played a crucial role in the Bodo Agreement, that today Assam is witnessing peace, development, and enthusiasm.

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Dr. Ben Lynch - MTHFR expert - explains in this one minute video why children with AUTISM should NEVER be given dairy - ANY DAIRY. Dairy BLOCKS folate from getting into the brain. And FOLATE is ESSENTIAL for brain health: Folate (vitamin B9) is essential for brain health, regulating DNA synthesis, repair, and methylation, which are critical for cognitive function, neurotransmitter production (serotonin, dopamine), and myelin sheath maintenance. It prevents neural tube defects in fetal development, supports neuron growth, and helps mitigate depression and cognitive decline.

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Tillis: If someone knowingly launched a second missile at that boat which led to the deaths of the other two, then they have to be held accountable and they shouldn't be in whatever role they're in.

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British psychiatrist Dr Joanna Moncrieff is the author of “Chemically Imbalanced: The Making and Unmaking of the Serotonin Myth.” She challenges the long-held belief that depression is caused by a lack of the hormone serotonin in the brain. “The serotonin myth… was first put out there in the 1960s, then picked up by the pharmaceutical industry in the 1990s, and widely propagated by them as part of their campaign to sell SSRIs—their new generation of antidepressants,” Moncrieff argues. "In the textbooks, we were being told we had these amazing new drugs… In reality, I saw hospitals where there were wards full of people who were zombified… heavily sedated, shuffling around." In our interview, she recounts how the serotonin myth took hold.

British psychiatrist Dr Joanna Moncrieff is the author of “Chemically Imbalanced: The Making and Unmaking of the Serotonin Myth.” She challenges the long-held belief that depression is caused by a lack of the hormone serotonin in the brain. “The serotonin myth… was first put out there in the 1960s, then picked up by the pharmaceutical industry in the 1990s, and widely propagated by them as part of their campaign to sell SSRIs—their new generation of antidepressants,” Moncrieff argues. "In the textbooks, we were being told we had these amazing new drugs… In reality, I saw hospitals where there were wards full of people who were zombified… heavily sedated, shuffling around." In our interview, she recounts how the serotonin myth took hold.

Jan Jekielek

33,685 views • 6 months ago

My entire SSRI series in one video. What doctors never tell you about SSRI withdrawal. Chris Masterjohn, PhD, Founder and Scientific Director of explains why SSRI withdrawal is mitochondrial dysfunction and what to do about it. This is not medical advice, diagnosis, or treatment. 29 million Americans and about 5-10% of the world's population are on SSRIs, which have become the first-line treatment of depression. These can cause sexual dysfunction and emotional blunting in up to half of people, an unclear incidence of sleep disruption, and a rare risk of suicidality, self-harm, and new-onset psychosis. On the other hand, 20-50% of people who go off experience SSRI discontinuation syndrome. This can involve irritability, anxiety, mood problems, crying, dread, suicidal ideation, insomnia, nightmares, excessive dreaming, lethargy, fatigue, headache, tremor, sweating, anorexia, flu-like symptoms, nausea, vomiting, diarrhea, pain, numbness, tingling, feeling like something is crawling on the skin, electric shocks running through the brain or body, rushing noises, visual traces (seeing something persist when it is no longer there, or seeing moving objects leaving illusory streaks of light behind them, etc), dizziness, light-headedness, "brain zaps," vertigo, confusion, difficulty concentrating, amnesia, genital hypersensitivity, and premature ejaculation. A closely related problem is post-SSRI sexual dysfunction (PSSD), which can cause total inability to feel the penis for males or for females the genitals and nipples, loss of sexual pleasure, weak orgasms, decreased libido, erectile dysfunction, and premature ejaculation. PSSD is often associated with general anhedonia, apathy, and poor mood. In this video, I maintain that the reason there are no good solutions to these problems is because we have completely misunderstood the role of serotonin and SSRIs. Serotonin's role is to help mitochondria adapt to changing demands for oxygen-based energy production. SSRIs enhance some of the mechanisms, and interfere with others. They enter the cell and stimulate independent mechanisms of mitochondrial stress adaptation, but in doing so they turn a cyclical and rhythmic pathway into a constantly stimulated one, creating mitochondrial dependence and making mitochondria vulnerable to new-onset dysfunction upon withdrawal. Once they make it to the mitochondria itself, the SSRIs act as mitochondrial toxins. Scientific references for everything can be found in the series on my web site. 0:30 SSRI Side Effects 1:00 SSRI Discontinuation Syndrome and PSSD 11:33 The Problem With Primary Care Doctors and Psychiatrists 14:56 The Reason We Don’t Have Good Solutions Is Because We Don’t Understand the Problem 16:22 Prozac Is a Performance-Enhancing Drug 18:40 Depression and Altitude 19:36 The Truth About Serotonin 25:10 How Serotonin Helps Us Breathe 30:05 Hypoxia Explains Why Serotonin Is So Abundant In the Gut 33:55 Serotonin, Melatonin, and the Mitochondria 35:50 Serotonin and Light 39:25 Intermittent Hypobaric Hypoxia Training 42:56 SSRIs Are Whole-Body, Primarily Non-Brain, Non-Neuronal, Mitochondrial Drugs 44:00 SSRIs and Birth Defects 46:37 SSRIs Deplete Serotonin 48:50 SSRIs Distort the Sigma-1 Receptor From a Cyclical to a Constant Activation 51:10 Different SSRIs Promote Different Ratios of Mitophagy and Mitochondrial Biogenesis 54:00 Going Off SSRIs Causes New-Onset Mitochondrial Dysfunction 58:30 Slow and Parabolic Tapers 1:02:10 What to Do About SSRI Withdrawal Mitochondrial Dysfunction Do You Have Hidden Mitochondrial Dysfunction? Mitochondrial dysfunction is one of the earliest signs of aging and chronic disease—and most people don’t know they have it. Mitome is the first at-home test that measures your cellular energy directly and gives you a personalized roadmap to optimize energy, slow aging, and protect against disease. Find it here at Mitome™

My entire SSRI series in one video. What doctors never tell you about SSRI withdrawal. Chris Masterjohn, PhD, Founder and Scientific Director of explains why SSRI withdrawal is mitochondrial dysfunction and what to do about it. This is not medical advice, diagnosis, or treatment. 29 million Americans and about 5-10% of the world's population are on SSRIs, which have become the first-line treatment of depression. These can cause sexual dysfunction and emotional blunting in up to half of people, an unclear incidence of sleep disruption, and a rare risk of suicidality, self-harm, and new-onset psychosis. On the other hand, 20-50% of people who go off experience SSRI discontinuation syndrome. This can involve irritability, anxiety, mood problems, crying, dread, suicidal ideation, insomnia, nightmares, excessive dreaming, lethargy, fatigue, headache, tremor, sweating, anorexia, flu-like symptoms, nausea, vomiting, diarrhea, pain, numbness, tingling, feeling like something is crawling on the skin, electric shocks running through the brain or body, rushing noises, visual traces (seeing something persist when it is no longer there, or seeing moving objects leaving illusory streaks of light behind them, etc), dizziness, light-headedness, "brain zaps," vertigo, confusion, difficulty concentrating, amnesia, genital hypersensitivity, and premature ejaculation. A closely related problem is post-SSRI sexual dysfunction (PSSD), which can cause total inability to feel the penis for males or for females the genitals and nipples, loss of sexual pleasure, weak orgasms, decreased libido, erectile dysfunction, and premature ejaculation. PSSD is often associated with general anhedonia, apathy, and poor mood. In this video, I maintain that the reason there are no good solutions to these problems is because we have completely misunderstood the role of serotonin and SSRIs. Serotonin's role is to help mitochondria adapt to changing demands for oxygen-based energy production. SSRIs enhance some of the mechanisms, and interfere with others. They enter the cell and stimulate independent mechanisms of mitochondrial stress adaptation, but in doing so they turn a cyclical and rhythmic pathway into a constantly stimulated one, creating mitochondrial dependence and making mitochondria vulnerable to new-onset dysfunction upon withdrawal. Once they make it to the mitochondria itself, the SSRIs act as mitochondrial toxins. Scientific references for everything can be found in the series on my web site. 0:30 SSRI Side Effects 1:00 SSRI Discontinuation Syndrome and PSSD 11:33 The Problem With Primary Care Doctors and Psychiatrists 14:56 The Reason We Don’t Have Good Solutions Is Because We Don’t Understand the Problem 16:22 Prozac Is a Performance-Enhancing Drug 18:40 Depression and Altitude 19:36 The Truth About Serotonin 25:10 How Serotonin Helps Us Breathe 30:05 Hypoxia Explains Why Serotonin Is So Abundant In the Gut 33:55 Serotonin, Melatonin, and the Mitochondria 35:50 Serotonin and Light 39:25 Intermittent Hypobaric Hypoxia Training 42:56 SSRIs Are Whole-Body, Primarily Non-Brain, Non-Neuronal, Mitochondrial Drugs 44:00 SSRIs and Birth Defects 46:37 SSRIs Deplete Serotonin 48:50 SSRIs Distort the Sigma-1 Receptor From a Cyclical to a Constant Activation 51:10 Different SSRIs Promote Different Ratios of Mitophagy and Mitochondrial Biogenesis 54:00 Going Off SSRIs Causes New-Onset Mitochondrial Dysfunction 58:30 Slow and Parabolic Tapers 1:02:10 What to Do About SSRI Withdrawal Mitochondrial Dysfunction Do You Have Hidden Mitochondrial Dysfunction? Mitochondrial dysfunction is one of the earliest signs of aging and chronic disease—and most people don’t know they have it. Mitome is the first at-home test that measures your cellular energy directly and gives you a personalized roadmap to optimize energy, slow aging, and protect against disease. Find it here at Mitome™

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Depression might not be a mental disorder. It could be a biological deficiency. Here’s the science: 90% of serotonin (the mood neurotransmitter) is made in the gut, not the brain. To make serotonin, your body needs to convert tryptophan through a process called methylation. If you can’t methylate properly, you can’t produce enough serotonin. What happens next? You’re told you have a mental illness and handed a prescription, but the root cause is never addressed.

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When SSRIs came out, the FDA was deluged with reports of suicide, homicide and mass shootings caused by those "antidepressants." Lawsuits then revealed the industry knew that risk, but, just like now, the FDA hid it from the public. This 1991 FDA hearing will blow you mind as many of these stories should have been immediate grounds to take SSRIs off the market-but instead more and more people keep getting put onto them. In this thread I'll show the suppressed data on the real dangers of SSRIs they keep covering up and never tell you about when you start the drugs.🧵

When SSRIs came out, the FDA was deluged with reports of suicide, homicide and mass shootings caused by those "antidepressants." Lawsuits then revealed the industry knew that risk, but, just like now, the FDA hid it from the public. This 1991 FDA hearing will blow you mind as many of these stories should have been immediate grounds to take SSRIs off the market-but instead more and more people keep getting put onto them. In this thread I'll show the suppressed data on the real dangers of SSRIs they keep covering up and never tell you about when you start the drugs.🧵

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SSRIs robbed my mom of 15 years of her life & forced two stints in rehab to wean her of them (and benzos). Today she’s 77 with dementia. Unless absolutely necessary, avoid taking serotonin reuptake inhibitors like the plague. This poor guy has a long road ahead.

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119,704 views • 1 year ago