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Introducing Open Science Index What if every open source science tool, AI model, dataset, and workflow across biology, chemistry, physics, materials science, and earth science lived together in one searchable place? That's the idea behind Open Science Index. Scientific tooling is exploding, and keeping up with what exists, and...

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The Genesis Mission calls for new ways to accelerate scientific discovery. This is our contribution Multimodal search across 25M papers is a step toward science discovery that moves at the speed of curiosity. Releasing, - Visually indexed scientific paper dataset with open access 25M papers, 450M+ visually indexed pages. Total 175TB+. All on Deep Lake - Open-source scientific data agent that achieves 48% SOTA on Humanity's Last Exam with tools including the indexed scientific research dataset. Excited to see what discoveries you all uncover with this. Try it and share your most interesting findings.
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The Genesis Mission calls for new ways to accelerate scientific discovery. This is our contribution Multimodal search across 25M papers is a step toward science discovery that moves at the speed of curiosity. Releasing, - Visually indexed scientific paper dataset with open access 25M papers, 450M+ visually indexed pages. Total 175TB+. All on Deep Lake - Open-source scientific data agent that achieves 48% SOTA on Humanity's Last Exam with tools including the indexed scientific research dataset. Excited to see what discoveries you all uncover with this. Try it and share your most interesting findings.

Davit

238,107 views • 9 months ago

Today we're announcing Base Labs, a dedicated research organization focused on advancing open-source AI. We believe in a healthy, open frontier model ecosystem. To enable this, we are working on: - Blue-sky research on continual learning, the science of RL, and how models learn across their full lifecycle, with every experiment and recipe shared openly. - The BaseHub Data Foundry: the highest-quality open RL environments, training data, and real-world benchmarks, built for anyone to train and benchmark on. - Post-post training: taking open-source models and making them better, safer, and more aligned through continual post-training, built on our research, and deployed with our frontier safety stack so organizations can use open-source models with confidence. - Making models cheaper and more performant through our model performance research. This is a mission-driven research effort, not a commercial product. We believe the health of the open-source AI ecosystem matters and that the best way to advance it is to do science in the open. We’re hiring engineers, researchers, and research fellows to advance this mission.
1:05

Today we're announcing Base Labs, a dedicated research organization focused on advancing open-source AI. We believe in a healthy, open frontier model ecosystem. To enable this, we are working on: - Blue-sky research on continual learning, the science of RL, and how models learn across their full lifecycle, with every experiment and recipe shared openly. - The BaseHub Data Foundry: the highest-quality open RL environments, training data, and real-world benchmarks, built for anyone to train and benchmark on. - Post-post training: taking open-source models and making them better, safer, and more aligned through continual post-training, built on our research, and deployed with our frontier safety stack so organizations can use open-source models with confidence. - Making models cheaper and more performant through our model performance research. This is a mission-driven research effort, not a commercial product. We believe the health of the open-source AI ecosystem matters and that the best way to advance it is to do science in the open. We’re hiring engineers, researchers, and research fellows to advance this mission.

Base Labs

207,637 views • 4 days ago

What does it mean when an AI model is “open weights” and how is it different than “open source”? Welcome to the next episode of the Open Model Series with merve, Hugging Face AI/ML engineer & open-sourceress! Every week we will discuss open-source & open-weight AI: what it is, how it works, and how you can run them on your own compute. Episode 3 out next week; episode 1 linked below. Please leave all your questions about open-source & open-weight AI in the comments. This is a super important topic that is novel to most people, and it can be challenging to grasp - so your questions are shared with many others.
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What does it mean when an AI model is “open weights” and how is it different than “open source”? Welcome to the next episode of the Open Model Series with merve, Hugging Face AI/ML engineer & open-sourceress! Every week we will discuss open-source & open-weight AI: what it is, how it works, and how you can run them on your own compute. Episode 3 out next week; episode 1 linked below. Please leave all your questions about open-source & open-weight AI in the comments. This is a super important topic that is novel to most people, and it can be challenging to grasp - so your questions are shared with many others.

Harper Carroll

32,624 views • 21 days ago

Introducing OpenScience. A better, open-source Claude Science. • Any model: GLM, Kimi, DeepSeek, Claude, GPT, your own fine-tune. Switching is one flag. • 250+ research skills across ML, comp bio, cheminformatics. All readable, editable, extensible. • No throttling, no gatekeeping, no one vendor deciding what science is okay. • Native Atlas integration: many agents, one shared reproducible research graph. • Runs on your infra. Your data stays yours. Scientific AI should be open. One company shouldn't own the tools the rest of us discover with, or decide who gets to.
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Introducing OpenScience. A better, open-source Claude Science. • Any model: GLM, Kimi, DeepSeek, Claude, GPT, your own fine-tune. Switching is one flag. • 250+ research skills across ML, comp bio, cheminformatics. All readable, editable, extensible. • No throttling, no gatekeeping, no one vendor deciding what science is okay. • Native Atlas integration: many agents, one shared reproducible research graph. • Runs on your infra. Your data stays yours. Scientific AI should be open. One company shouldn't own the tools the rest of us discover with, or decide who gets to.

Synthetic Sciences (YC W26)

241,307 views • 2 months ago

Thrilled to see Amazon Web Services making a major contribution to the open source AI community with the launch of the Strands Agents, an open source AI agents SDK! The core of Strands is the simple agentic loop that connects the model and tools together, like the two strands of DNA. This model-driven approach to agent building eliminates the need for complex agent orchestration by embracing the capabilities of state-of-the-art models to plan, chain thoughts, call tools, and reflect. Providing open source tools and interoperability with open source protocols is an important part of our strategy to enable an agentic future. Can't wait to see what you build with Strands!
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Thrilled to see Amazon Web Services making a major contribution to the open source AI community with the launch of the Strands Agents, an open source AI agents SDK! The core of Strands is the simple agentic loop that connects the model and tools together, like the two strands of DNA. This model-driven approach to agent building eliminates the need for complex agent orchestration by embracing the capabilities of state-of-the-art models to plan, chain thoughts, call tools, and reflect. Providing open source tools and interoperability with open source protocols is an important part of our strategy to enable an agentic future. Can't wait to see what you build with Strands!

Swami Sivasubramanian

32,185 views • 1 year ago

Announcing the Open Model Series: a new series on open source AI models, with merve of Hugging Face. Hugging Face is the open model hub: it hosts model weights, datasets, evals, & demo apps, and maintains the open-source libraries (like transformers) used to run and train them. I think of it like GitHub, but for AI models. You can download open models and run them on your own machines. In this series we'll cover what open source and open weight models are, how they work, how to run them yourself, and why they're important. By the way - this video is edited entirely with Claude! I can make a tutorial on how I did it. If there's a question you want answered about open models, leave it in the comments. We will read them all. Episode 1 is out soon.
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Announcing the Open Model Series: a new series on open source AI models, with merve of Hugging Face. Hugging Face is the open model hub: it hosts model weights, datasets, evals, & demo apps, and maintains the open-source libraries (like transformers) used to run and train them. I think of it like GitHub, but for AI models. You can download open models and run them on your own machines. In this series we'll cover what open source and open weight models are, how they work, how to run them yourself, and why they're important. By the way - this video is edited entirely with Claude! I can make a tutorial on how I did it. If there's a question you want answered about open models, leave it in the comments. We will read them all. Episode 1 is out soon.

Harper Carroll

30,392 views • 1 month ago

🤗🤗🤗introducing Hugging Science -- the home of AI for science 🤗🤗🤗 open models and datasets are the powerhouse of science (see the PDB), but finding the models and data you actually need for your breakthrough is hard af you shouldn't need to scrape arxiv, own your own wetlab, fight a custom HDF5 parser, build a fusion stellarator, and beg for compute before you've trained a single epoch so we're changing that we've put all the best science on Hugging Face in one place: - 78GB of genomics data - 11TB of PDE simulations - 100M cell profiles - 9T DNA base pairs - 13M molecular trajectories - 400k medical QA pairs and much more, all open, and all ready for training (+ you can also now filter and search by domain, task, and keyword) we've put together all the biggest releases from our partners at NASA, Google, OpenAI, Meta FAIR, Arc Institute, Ginkgo, SandboxAQ, Proxima Fusion, NVIDIA, Ai2, OpenADMET, InstaDeep, Future House, Polymathic AI, LeMaterial, Earth Species Project, Merck, and Eve Bio if you're not sure where you fit in -- work on open challenges for problems that matter: including fusion stellarator design, ADMET, antibody developability, multilingual medicine, catalysis and materials, and scientific reasoning. we're already changing how science gets done: a fusion startup needed a benchmark for stellarator plasma confinement that didn't exist. Proxima Fusion shipped ConStellaration on Hugging Science: a leaderboard, dataset, and eval metrics, all in one place. a drug discovery team wanted to predict hPXR induction. OpenADMET put up a blind challenge: 11,000+ compounds assayed at Octant, 513 held out, two tracks (pEC50 + structure). Anyone in the world can train and submit. an antibody team at Ginkgo Bioworks released GDPa1, a developability dataset for stability, manufacturability, and immunogenicity prediction, with a live leaderboard scoring every submission. if you know a problem the ML community should be working on, let us know. make a challenge! this is about putting all the tools for solving science in one place. so we can hillclimb! →
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🤗🤗🤗introducing Hugging Science -- the home of AI for science 🤗🤗🤗 open models and datasets are the powerhouse of science (see the PDB), but finding the models and data you actually need for your breakthrough is hard af you shouldn't need to scrape arxiv, own your own wetlab, fight a custom HDF5 parser, build a fusion stellarator, and beg for compute before you've trained a single epoch so we're changing that we've put all the best science on Hugging Face in one place: - 78GB of genomics data - 11TB of PDE simulations - 100M cell profiles - 9T DNA base pairs - 13M molecular trajectories - 400k medical QA pairs and much more, all open, and all ready for training (+ you can also now filter and search by domain, task, and keyword) we've put together all the biggest releases from our partners at NASA, Google, OpenAI, Meta FAIR, Arc Institute, Ginkgo, SandboxAQ, Proxima Fusion, NVIDIA, Ai2, OpenADMET, InstaDeep, Future House, Polymathic AI, LeMaterial, Earth Species Project, Merck, and Eve Bio if you're not sure where you fit in -- work on open challenges for problems that matter: including fusion stellarator design, ADMET, antibody developability, multilingual medicine, catalysis and materials, and scientific reasoning. we're already changing how science gets done: a fusion startup needed a benchmark for stellarator plasma confinement that didn't exist. Proxima Fusion shipped ConStellaration on Hugging Science: a leaderboard, dataset, and eval metrics, all in one place. a drug discovery team wanted to predict hPXR induction. OpenADMET put up a blind challenge: 11,000+ compounds assayed at Octant, 513 held out, two tracks (pEC50 + structure). Anyone in the world can train and submit. an antibody team at Ginkgo Bioworks released GDPa1, a developability dataset for stability, manufacturability, and immunogenicity prediction, with a live leaderboard scoring every submission. if you know a problem the ML community should be working on, let us know. make a challenge! this is about putting all the tools for solving science in one place. so we can hillclimb! →

Georgia Channing

226,020 views • 4 months ago

Episode 242: Khala, Collective Intelligence We release our new flagship product in research preview. Khala is the first open-source orchestrator of models, agents, tools, skills & programs behind a familiar OpenAI-compatible API endpoint. Unlike the closed orchestrators (OpenRouter Fusion, Sakana Fugu): ours is fully open end to end; every call is metered and inspectable — you can see what ran, what it cost, and who did the work; and it's built to pay them, in bitcoin, for the compute, data, labor, and verification they contribute. Under the hood it's our Blueprint system — DSPy for the orchestrator: every module is its own signature, independently optimizable via GEPA and independently discoverable + monetizable on our marketplace. Improve one piece, the whole collective gets better. And it improves instead of depreciating: our Tassadar training run is how the collective trains its own open models and compiles verifiable-by-replay specialists that plug straight into Khala. We are thrilled to begin organizing the world's intelligence into one open network accessible to all people and agents. Try it for free 👉
6:16

Episode 242: Khala, Collective Intelligence We release our new flagship product in research preview. Khala is the first open-source orchestrator of models, agents, tools, skills & programs behind a familiar OpenAI-compatible API endpoint. Unlike the closed orchestrators (OpenRouter Fusion, Sakana Fugu): ours is fully open end to end; every call is metered and inspectable — you can see what ran, what it cost, and who did the work; and it's built to pay them, in bitcoin, for the compute, data, labor, and verification they contribute. Under the hood it's our Blueprint system — DSPy for the orchestrator: every module is its own signature, independently optimizable via GEPA and independently discoverable + monetizable on our marketplace. Improve one piece, the whole collective gets better. And it improves instead of depreciating: our Tassadar training run is how the collective trains its own open models and compiles verifiable-by-replay specialists that plug straight into Khala. We are thrilled to begin organizing the world's intelligence into one open network accessible to all people and agents. Try it for free 👉

OpenAgents

238,777 views • 2 months ago

Joe Rogan and Perplexity CEO Aravind Srinivas get into a serious conversation about Fauci and “The Science.” ROGAN: "One of the things that was really weird about the whole COVID pandemic was that we weren't supposed to question science… when Fauci said if you question Anthony Fauci, you are questioning science." SRINIVAS: "That's because they try to assign credibility through their degrees, through their affiliations... but not through the scientific method. Anybody should be allowed to ask questions, as long as they are open to new evidence. And that's the most important quality of a scientist." ROGAN: "There was an actual government push to silence questioning, and legitimate researchers were kicked off of Twitter because they didn't back the narrative. This is all anti-science." SRINIVAS: "Curbing that is almost like a way of saying, 'Look, I'm going to tell you what happened. You need to believe in my worldview, and I'm not open to new perspectives.'" Science demands questioning. The moment someone tells you not to, they've stopped doing science.
1:22

Joe Rogan and Perplexity CEO Aravind Srinivas get into a serious conversation about Fauci and “The Science.” ROGAN: "One of the things that was really weird about the whole COVID pandemic was that we weren't supposed to question science… when Fauci said if you question Anthony Fauci, you are questioning science." SRINIVAS: "That's because they try to assign credibility through their degrees, through their affiliations... but not through the scientific method. Anybody should be allowed to ask questions, as long as they are open to new evidence. And that's the most important quality of a scientist." ROGAN: "There was an actual government push to silence questioning, and legitimate researchers were kicked off of Twitter because they didn't back the narrative. This is all anti-science." SRINIVAS: "Curbing that is almost like a way of saying, 'Look, I'm going to tell you what happened. You need to believe in my worldview, and I'm not open to new perspectives.'" Science demands questioning. The moment someone tells you not to, they've stopped doing science.

The Vigilant Fox 🦊

194,809 views • 2 months ago

David Sacks: Anthropic Is Trying to Crush Open Source AI and the American Developers Who Use It David Sacks: “I know people don't have a lot of sympathy for Chinese companies, that's fine. I'm not defending Chinese companies. I'm defending American developers who need to be able to use everything in the public domain. And let me give you an example. Cursor rolled out its new product, Composer 2. They were able to post-train that model using Kimi K2.5 on their own proprietary coding data. They started with a Chinese open source model, and then they used their own data, and they came up with a new derivative product. This is the way that open source works. You take things that are in the public domain, you fork them, you make them your own. And by the way, once it's in the public domain, it's not a Chinese model anymore. No data is going back to China, nothing's going back to China. An American company has taken open source contributions in the public domain, made it their own, and then developed their own model. And if you say that American companies can't do that, or that somehow it's tainted with IP theft, you are basically going to put a dagger through the heart of the entire American open source ecosystem. And that is exactly what Anthropic wants, because they do not want to have the competition.”
0:59

David Sacks: Anthropic Is Trying to Crush Open Source AI and the American Developers Who Use It David Sacks: “I know people don't have a lot of sympathy for Chinese companies, that's fine. I'm not defending Chinese companies. I'm defending American developers who need to be able to use everything in the public domain. And let me give you an example. Cursor rolled out its new product, Composer 2. They were able to post-train that model using Kimi K2.5 on their own proprietary coding data. They started with a Chinese open source model, and then they used their own data, and they came up with a new derivative product. This is the way that open source works. You take things that are in the public domain, you fork them, you make them your own. And by the way, once it's in the public domain, it's not a Chinese model anymore. No data is going back to China, nothing's going back to China. An American company has taken open source contributions in the public domain, made it their own, and then developed their own model. And if you say that American companies can't do that, or that somehow it's tainted with IP theft, you are basically going to put a dagger through the heart of the entire American open source ecosystem. And that is exactly what Anthropic wants, because they do not want to have the competition.”

The All-In Podcast

278,276 views • 1 month ago

Earlier this week at GTC, we announced our partnership with Nvidia. We will work with Nvidia to build strong, American open-source models that are at the frontier of scientific reasoning. These models will be essential for the US to compete with China on science in the coming decades. Jensen is committing to spend tens of billions of dollars developing open-source models, and we are excited to be a partner with them in figuring out how to benchmark, train and use those agents to accelerate scientific research. We have already open-sourced some of the work we have done with them, and are looking forward to open-sourcing more. There are few things today that are more important. See our blog post below, and watch the video to learn more, narrated by the man himself.
1:44

Earlier this week at GTC, we announced our partnership with Nvidia. We will work with Nvidia to build strong, American open-source models that are at the frontier of scientific reasoning. These models will be essential for the US to compete with China on science in the coming decades. Jensen is committing to spend tens of billions of dollars developing open-source models, and we are excited to be a partner with them in figuring out how to benchmark, train and use those agents to accelerate scientific research. We have already open-sourced some of the work we have done with them, and are looking forward to open-sourcing more. There are few things today that are more important. See our blog post below, and watch the video to learn more, narrated by the man himself.

Sam Rodriques

24,295 views • 5 months ago

We are now Cult.Repo. The original creators behind the iconic Open Source documentaries (Vue, React, GraphQL) are back together! Honeypot is now called Cult.Repo and is independently-owned. We are on a mission to document the complete history of every major open source language ever created. With 250K subscribers and over 15M views, we're building on our foundation as creators of the acclaimed Open Source Origin Story documentary format. Coming in 2025: Python Software Foundation, Vite ⚡ documentaries and much more. Our independence is core to our mission. We believe the human stories behind open source deserve authentic, in-depth storytelling. Our new model is powered directly by: - Community support from viewers - Sponsorships from organizations that champion open source This transition represents our commitment to independent, meaningful tech storytelling that honours the collaborative spirit of open source itself.
0:42

We are now Cult.Repo. The original creators behind the iconic Open Source documentaries (Vue, React, GraphQL) are back together! Honeypot is now called Cult.Repo and is independently-owned. We are on a mission to document the complete history of every major open source language ever created. With 250K subscribers and over 15M views, we're building on our foundation as creators of the acclaimed Open Source Origin Story documentary format. Coming in 2025: Python Software Foundation, Vite ⚡ documentaries and much more. Our independence is core to our mission. We believe the human stories behind open source deserve authentic, in-depth storytelling. Our new model is powered directly by: - Community support from viewers - Sponsorships from organizations that champion open source This transition represents our commitment to independent, meaningful tech storytelling that honours the collaborative spirit of open source itself.

Cult.Repo

71,390 views • 1 year ago

Priscilla Chan and Mark Zuckerberg co-founded the Chan Zuckerberg Initiative (CZI) in 2015, committing 99% of their Meta shares to advance science, education, and opportunity. As a pediatrician and CEO of Meta respectively, they've built CZI into one of the most ambitious technology-driven philanthropic organizations with a moonshot goal to help cure, prevent, or manage all diseases by the end of the century. In this episode, we sit down with Priscilla and Mark to unpack how CZI bridges state-of-the-art AI with open biomedical research, their investments in open-source tools like the Human Cell Atlas, their philosophy on building teams across different disciplines, and what they envision the future of healthcare. Chan Zuckerberg Initiative swyx Alessio Fanelli
1:51

Priscilla Chan and Mark Zuckerberg co-founded the Chan Zuckerberg Initiative (CZI) in 2015, committing 99% of their Meta shares to advance science, education, and opportunity. As a pediatrician and CEO of Meta respectively, they've built CZI into one of the most ambitious technology-driven philanthropic organizations with a moonshot goal to help cure, prevent, or manage all diseases by the end of the century. In this episode, we sit down with Priscilla and Mark to unpack how CZI bridges state-of-the-art AI with open biomedical research, their investments in open-source tools like the Human Cell Atlas, their philosophy on building teams across different disciplines, and what they envision the future of healthcare. Chan Zuckerberg Initiative swyx Alessio Fanelli

Latent.Space

166,190 views • 10 months ago

Livestream Alert: Open World Models in Production: LTX.io and ComfyUI Founders Live A special live conversation with Yoland Yan ( CEO, ComfyUI ) & comfyanonymous ( Founder, ComfyUI ) and Zeev Farbman ( CEO, LTX ) Join us as we sit down with the teams behind LTX and ComfyUI to talk about building an open world model that integrates natively into the production tools creators use. We'll explore what it took to build LTXa foundational model that understands space, motion, and how the physical world operates—with synchronized video and audio generation, truly open weights, and the flexibility to fine-tune on your own data. We'll explore what it took to ship a frontier video model in the open, how LTX and ComfyUI are building the pipeline for AI-driven production together, and what it means for creators, developers, and the wider open-source ecosystem. What we'll cover: → LTX: the open world model for synchronized video + audio, and beyond → Native integration into ComfyUI workflows and production pipelines → Open world models vs. closed platforms and where things are headed → Fine-tuning LTX on your own data with LTX Trainer → Community Q&A — bring your questions
0:20

Livestream Alert: Open World Models in Production: LTX.io and ComfyUI Founders Live A special live conversation with Yoland Yan ( CEO, ComfyUI ) & comfyanonymous ( Founder, ComfyUI ) and Zeev Farbman ( CEO, LTX ) Join us as we sit down with the teams behind LTX and ComfyUI to talk about building an open world model that integrates natively into the production tools creators use. We'll explore what it took to build LTXa foundational model that understands space, motion, and how the physical world operates—with synchronized video and audio generation, truly open weights, and the flexibility to fine-tune on your own data. We'll explore what it took to ship a frontier video model in the open, how LTX and ComfyUI are building the pipeline for AI-driven production together, and what it means for creators, developers, and the wider open-source ecosystem. What we'll cover: → LTX: the open world model for synchronized video + audio, and beyond → Native integration into ComfyUI workflows and production pipelines → Open world models vs. closed platforms and where things are headed → Fine-tuning LTX on your own data with LTX Trainer → Community Q&A — bring your questions

ComfyUI

13,174 views • 1 month ago

“We have a crisis of open source models in the Western world. Outside of China, there are no good open source models. We don't even have any in the US now. The talent, the capital and the focus to be best-in-class at pre-training, mid-training, post-training is an extremely scarce skillset. The answer for a lot of countries may just be to take an open weights model from China, post-train or fine-tune their own version, and have that be what they start from." Everett Randle Why does the West have such poor open source models and is it a national security threat to rely on open-source Chinese models Demis Hassabis Yann LeCun Aidan Gomez Lilian Weng Jan Leike
1:20

“We have a crisis of open source models in the Western world. Outside of China, there are no good open source models. We don't even have any in the US now. The talent, the capital and the focus to be best-in-class at pre-training, mid-training, post-training is an extremely scarce skillset. The answer for a lot of countries may just be to take an open weights model from China, post-train or fine-tune their own version, and have that be what they start from." Everett Randle Why does the West have such poor open source models and is it a national security threat to rely on open-source Chinese models Demis Hassabis Yann LeCun Aidan Gomez Lilian Weng Jan Leike

Harry Stebbings

63,738 views • 2 months ago

We’re excited to share that 🥇Llama Nemotron Super 49B v1.5 -- our latest open reasoning model -- is now #1 on the Artificial Analysis Intelligence Index - a leaderboard that spans advanced math, science, and agentic tasks, in the 70B open model category. Llama Nemotron Super 49B v1.5 is trained with high-quality reasoning synthetic data generated from models like Qwen3-235B and DeepSeek R1. It delivers state-of-the-art accuracy and throughput, running on a single H100. Key features: 🎯 Leading accuracy on multi-step reasoning, math, coding, and function-calling 🏗️ Post-trained using RPO, DPO, and RLVR across 26M+ synthetic examples 📊 Fully transparent training data and techniques If you're building AI agents and want a high accuracy, fully-open, and transparent reasoning model that you can deploy anywhere, try Super v1.5 on or download from Hugging Face 🤗 ➡️ Leaderboard:
0:54

We’re excited to share that 🥇Llama Nemotron Super 49B v1.5 -- our latest open reasoning model -- is now #1 on the Artificial Analysis Intelligence Index - a leaderboard that spans advanced math, science, and agentic tasks, in the 70B open model category. Llama Nemotron Super 49B v1.5 is trained with high-quality reasoning synthetic data generated from models like Qwen3-235B and DeepSeek R1. It delivers state-of-the-art accuracy and throughput, running on a single H100. Key features: 🎯 Leading accuracy on multi-step reasoning, math, coding, and function-calling 🏗️ Post-trained using RPO, DPO, and RLVR across 26M+ synthetic examples 📊 Fully transparent training data and techniques If you're building AI agents and want a high accuracy, fully-open, and transparent reasoning model that you can deploy anywhere, try Super v1.5 on or download from Hugging Face 🤗 ➡️ Leaderboard:

NVIDIA AI Developer

100,506 views • 1 year ago

🧬 Excited to open-source Biomni! With just a few lines of code, you can now automate biomedical research with AI agent! We are releasing Biomni A1 (agent) + E1 (env) with 150 specialized tools, 59 databases, and 105 software. E1 is our first attempt at curating the bio-agent environment, but it only scratches the surface: Call to help build Biomni-E2 - an open environment for bio-agent, built with and for the community! We welcome new tools, benchmarks, datasets, agents, and beyond to build the environment together. Significant contributors will be invited as co-authors on our upcoming E2 manuscript. More to come! 💻 🌐 Biomni
0:37

🧬 Excited to open-source Biomni! With just a few lines of code, you can now automate biomedical research with AI agent! We are releasing Biomni A1 (agent) + E1 (env) with 150 specialized tools, 59 databases, and 105 software. E1 is our first attempt at curating the bio-agent environment, but it only scratches the surface: Call to help build Biomni-E2 - an open environment for bio-agent, built with and for the community! We welcome new tools, benchmarks, datasets, agents, and beyond to build the environment together. Significant contributors will be invited as co-authors on our upcoming E2 manuscript. More to come! 💻 🌐 Biomni

Kexin Huang

34,834 views • 1 year ago

FDA’s Dangerous Betrayal of Science & Transparency: A Warning from Dr. Marty Makary "We just watched our government do the most dangerous thing a government could ever do." Dr. Marty Makary, renowned surgeon and public health expert, delivers a chilling indictment of the FDA’s reckless approval of a novel vaccine for young, healthy kids—despite internal dissent. Two top vaccine experts were fired for opposing its authorization. Then, the government mandated it, silenced doctors demanding data, and crushed scientific debate. This isn’t just failure—it’s a fundamental betrayal of science. Science thrives on transparency, skepticism, and evolving with evidence. Instead, we got censorship, coercion, and blind allegiance from the very institutions meant to protect public trust. "The purpose of science is open dialogue—to disagree, question, and adapt as data emerges." Yet today, doctors are punished for asking questions, data is hidden, and dissent is labeled "misinformation." This isn’t science—it’s authoritarianism in a lab coat. If we don’t demand accountability now, what will they force next?
0:46

FDA’s Dangerous Betrayal of Science & Transparency: A Warning from Dr. Marty Makary "We just watched our government do the most dangerous thing a government could ever do." Dr. Marty Makary, renowned surgeon and public health expert, delivers a chilling indictment of the FDA’s reckless approval of a novel vaccine for young, healthy kids—despite internal dissent. Two top vaccine experts were fired for opposing its authorization. Then, the government mandated it, silenced doctors demanding data, and crushed scientific debate. This isn’t just failure—it’s a fundamental betrayal of science. Science thrives on transparency, skepticism, and evolving with evidence. Instead, we got censorship, coercion, and blind allegiance from the very institutions meant to protect public trust. "The purpose of science is open dialogue—to disagree, question, and adapt as data emerges." Yet today, doctors are punished for asking questions, data is hidden, and dissent is labeled "misinformation." This isn’t science—it’s authoritarianism in a lab coat. If we don’t demand accountability now, what will they force next?

Camus

84,870 views • 1 year ago

We already have a superintelligence. It's called civilization. Humans, institutions, and now AI agents all interact among each other in one big economy. Allison Duettmann's take is that the real project in such a system is building and preparing AI enabled institutions on top of what already works. Her other argument is that science stayed open for centuries and that has lead to a flourishing outcome for humanity as a whole. Now the frontier models are putting guardrails and restrictions. Open source AI plus community compute ( personally, for me, this definitely resonates with the project Darkbloom) might end up being the only independent path for doing real science outside the labs. 0:25 AI for flourishing, not just fear 4:21 Amateurs vs Google's quantum result 7:06 Decentralized inference on MacBooks 11:58 Civilization as superintelligence 15:38 The case for cryonics Full episode with PostAGI.
16:43

We already have a superintelligence. It's called civilization. Humans, institutions, and now AI agents all interact among each other in one big economy. Allison Duettmann's take is that the real project in such a system is building and preparing AI enabled institutions on top of what already works. Her other argument is that science stayed open for centuries and that has lead to a flourishing outcome for humanity as a whole. Now the frontier models are putting guardrails and restrictions. Open source AI plus community compute ( personally, for me, this definitely resonates with the project Darkbloom) might end up being the only independent path for doing real science outside the labs. 0:25 AI for flourishing, not just fear 4:21 Amateurs vs Google's quantum result 7:06 Decentralized inference on MacBooks 11:58 Civilization as superintelligence 15:38 The case for cryonics Full episode with PostAGI.

Soubhik Deb

11,759 views • 1 month ago

I’m excited to share Deputies, an open source control plane for background coding agents! The goal is simple: move agentic software development off individual laptops and into a central hub where teams can see what agents are doing, review their outputs, and keep a traceable history of the work. Inspired by systems like Inspect/Open-Inspect, Minions, and Open SWE, I built Deputies on top of fks's Flue Framework. It’s designed to run in your own infrastructure and trust boundaries, with Slack/GitHub integrations and Daytona + Docker sandbox support.
8:51

I’m excited to share Deputies, an open source control plane for background coding agents! The goal is simple: move agentic software development off individual laptops and into a central hub where teams can see what agents are doing, review their outputs, and keep a traceable history of the work. Inspired by systems like Inspect/Open-Inspect, Minions, and Open SWE, I built Deputies on top of fks's Flue Framework. It’s designed to run in your own infrastructure and trust boundaries, with Slack/GitHub integrations and Daytona + Docker sandbox support.

Sid Palas

12,965 views • 3 months ago