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Introducing our BRAND NEW in-house fully functional lab‼️ created by Founder, Paul Han Haptica, Flexible Touch Panels for Robotic Skin & More the inventors residency of san francisco We have transformed our space to include: UV & IR Galvo Lasers SLA & FDM Printing Plasma Etching & Chemical Processing...

21,449 görüntüleme • 10 ay önce •via X (Twitter)

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Karl Popper on How We Gain Knowledge: ––Karl Popper: "People think, usually, that we acquire knowledge by opening our eyes and our ears and let the sensations stream into us, and they believe then that we record this like a camera. In my opinion, if we wish to get knowledge, we have to have a problem. It has to be knowledge of something. We have to find out something. We don't have to wait for information to stream into us, but we have to be inquisitive if we want to get knowledge. If we were passive, we would gain a confused mass of sensations or something like that, which we would hardly be able to understand and to convert into what one may call knowledge. Quite apart from that, perception is not really, in my opinion, the main source of our knowledge. The role of perception is to inform us about a momentary situation in our environment. But we couldn't really interpret our perceptions without knowing much more about our environment, namely, we know whether we are in a house or whether we are in a glacier. So we have two kinds of knowledge: this wider knowledge of a frame in which we orientate ourselves, and the momentary perception which gives us information about the situation at that particular moment. And it is only this situation in which we can use our perception. So we have theoretical knowledge and, if you like, the momentary practical challenge to our theoretical knowledge. And here comes perception in."

Karl Popper Quotes

115,200 görüntüleme • 3 ay önce

Welcome to the Lab of the Future! 🧬🤖 Excited to share LUMI-lab, out today in Cell — a self-driving platform that pairs an AI foundation model with a robotic lab to autonomously discover ionizable lipids (LNPs) for mRNA delivery. The core problem: Designing lipid nanoparticles (LNPs) is hard. The chemical space of ionizable lipids is vast, experimental cycles are slow, and — critically — historical LNP datasets are far too small to train a predictive model from scratch. Most AI approaches in this space hit a wall immediately: not enough data to learn from. Our solution: lab-in-the-loop foundation model learning. Instead of training on LNP data alone, LUMI starts as a transformer-based foundation model pretrained across broad chemical space, building rich molecular representations before it ever sees a single LNP experiment. Then it enters a closed loop with a robotic synthesis platform: predict → synthesize → assay → update. Each round of real wet-lab experiments fine-tunes the model, which then proposes smarter candidates for the next round. The lab isn't just validating AI predictions — it's actively teaching the model, continuously. What happened when we let it run: LUMI-lab autonomously synthesized and screened 1,700+ ionizable lipids in human bronchial epithelial cells. The top candidate — LUMI-6 — features a brominated lipid tail, a structural motif that had been largely overlooked in LNP design. LUMI found it without being told where to look. When formulated into LNPs and delivered intratracheally to mice, LUMI-6 achieved 20.3% gene editing efficiency in lung epithelial cells — a compelling result for one of the hardest-to-reach therapeutic targets, directly relevant to diseases like cystic fibrosis and alpha-1 antitrypsin deficiency. Why this matters beyond LNPs: This is a proof of concept for a broader thesis — that foundation model pretraining + active learning + robotic experimentation can overcome the data scarcity bottleneck that plagues AI-driven discovery in biology. You don't need a massive domain-specific dataset to start. You need a model that can generalize, a lab that can generate the right data, and a loop that connects them. Huge congratulations to first authors Yue Xu, Haotian Cui, and Kuan Pang, and to the entire Bowen LI team. Grateful to our collaborators at University Health Network and Leslie Dan Faculty of Pharmacy, and to Princess Margaret Cancer Centre Research Princess Margaret Cancer Centre Research. 📄 Paper:

Bo Wang

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More footage of the first documented cougar family in Minnesota in the past century. Volume up for the full experience. More to come soon! Our goal is to learn as much as we can about these cougars in the coming months. But we could really use some help covering costs associated with this research. For instance, we collected 9 scats at this kill and they are on their way to a lab for genetic analysis to try to get individual genetics and determine what western population the mom and dad originated from. Genetic samples cost ~$55-70 per sample, depending on the type and quality of the sample. Your support helps us cover costs like this, and gives us the ability and resources to study these individuals, and any others out there we might learn of. By donating at the link below, you directly support this research. Plus, the support helps us have the capacity to send in any samples we collect in the coming months.Once we have results, we will share with everyone! Notably, we also analyze the genetic samples from every adult wolf we collar, pup we tag, or dead wolf we come across. That work has been supported ENTIRELY by folks donating to our project, and the results have provided a wealth of information on wolf pack and population dynamics. And this work will only continue if generous folks continue to support our work. E.g., a $70 donation ensures we can get the genetics of a wolf. So please donate to our annual fundraiser to support our research, help us cover these costs, and keep this research going! Donate here:

Voyageurs Wolf Project

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It’s time. Introducing the Iris NFTs: Your gateway to the Iris DAO ecosystem. Iris DAO is an art collective that connects minority artists and collectors. Join the allowlist now 👉 Our mission is to bring about a revolution in the issue of diversity. Currently, artists from various minority groups encounter barriers that hinder their full potential due to biases related to age, gender, race, and other factors. These limitations result in unequal opportunities for minority artists, creating a significant lack of diversity. • Only 15% of digital art sales are by women artists. • 85% of artworks displayed in American museums are created by white artists. Even our 17 yo founder @Mark_Teenage faced criticism and hardship solely based on his age. They judged Mark without acknowledging his skills. We focus on providing support to minority groups, offering new opportunities and platforms for self-expression. What are Iris NFTs? Iris NFT grants exclusive access to the Iris Ecosystem, uniting curated collectors and artists on a mission to champion diversity. In addition to membership to the Iris's artists and collectors community, Iris NFT holders gain access to unique experiences throughout the Iris Ecosystem. Our allowlist is now open, but spaces are limited. We are carefully selecting individuals who align with our mission and values. This NFT isn’t just an investment; it comes with voting power. We want owners who are genuinely committed to supporting minorities and fostering inclusivity. If you’re here for a quick profit, this isn’t the right opportunity for you. However, if you believe in our cause and want to make a positive impact, we encourage you to apply. Explore more about us on our brand new website. Finally, We would like to extend our heartfelt thanks to all our partners, advisors, artists, and investors for being with us on this journey. A special thanks to our partner, manifold.xyz, for helping us deliver the best NFTs and support artists together. We also want to express our gratitude to our amazing partners: Forbes Web3, JJ, WAW, world of women, One Love Art DAO, and more partners that will be announced soon. Additionally, a huge shoutout to our incredible advisors: medved, Shannon Snow, and Mani. Lastly, thank you to all of our wonderful artist partners who are leading this space: Sara "Sparky" Baumann ⚡️, 𝓶𝓾𝓶𝓫𝓸𝓽, Andrea ✧, Rhi, Aoife O’Dwyer, Teresa Melvin, @Mireyita_art, Anastasia NFTart 💎 🫶 Thank you all for your support to achieve the diversity. In this tough bear market, we've been dedicated to building a platform that truly supports artists. We're not trying to ride any trends; we genuinely care about artists and are here to offer our support. We understand the market conditions are still challenging, but this initiative is about much more than money. If you are an artist, a collector, or even someone new to this space who wants to support minorities, this NFT is for you. We are using NFTs as a tool to address the issue of diversity in the space. We believe that the success of this project will provide new opportunities and platforms for minority artists in the Web3 space, fostering diversity and inclusivity. Thank you so much for reading through this. Even small support, like a repost, is incredibly meaningful to us and can make a big difference. Your support helps us reach more people and amplify the voices of minority artists. If you would like to be a part of this initiative, please sign up for the allowlist: We eagerly await your cooperation. Let's build a new future together.

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THIS IS A CALL TO EVERY MAN & WOMAN IN IRELAND...IT'S TIME Will you answer Ireland's call at this pivotal turning point in our history? After Gardaí (and PSNI) ambushed the men who feed us? The men who deliver the goods we need? Men who we will have no food without? Men who work hard and are robbed blind? Like the rest of us are robbed? Men peacefully protesting to save their livelihoods and feed their children? Will you stand by after 14-year-old boys were pepper sprayed? After women were pushed over by those who swore to protect us? Will you condone tractors and trucks being seized even after peaceful protesters stepped down? Will you send a message that ambushing peaceful men in the middle of the night is not going to be tolerated? We all know something is JUST NOT RIGHT in Ireland (and in other EU countries). We all feel it in our gut. Our bones. Our souls. We see it in the cost of everything. We see it in our bare cupboards. We see it in our empty wallets. We see it at the fuel pumps. We see it in the house prices. We see it when we watch entire town loads of our young leave Ireland because they have no choice. We see it in government actions that never benefit us, but always benefit someone else. We see how our opinions and protestations are turned into attacks on our characters. We see wrongdoing all around us and the truth is we have been far too compliant for far too long. Ireland is a country with plentiful natural resources, all given away, all for greed. It is a great little country, for everyone other than us. For politicians friends. For data centres. Corporations and Globalists with agendas that will forever change the course of our country and the future of her people. The government, like many others, is actively attempting to decimate our farmers and more besides. Replace our food with lab grown meat, EU sanctioned cricket meal and massive industrial GMO corporate farming. There are bigger agendas at play and those we pay no longer serve us and we know they will send riot police for us too. Things are going to get bad. What had happened with our farmers and hauliers will not be an isolated event. There is no denying that. We can no longer sit at home and watch from the sidelines, and we are running out of time. Our children and grandchildren need us to get off our knees. Rise up. IT'S TIME TO GET MAD. It's time to say "I'M AS MAD AS HELL, AND I'M NOT GOING TO TAKE THIS ANYMORE!". Please watch until the end. Follow us IrishInquiry. Thank you all.

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37,349 görüntüleme • 4 ay önce

Over the past few months at Dedalus Labs, we’ve noticed how many talented founders from around the world are being held back by one thing: location. There is no better place in the world to build an AI startup than San Francisco. SF is home to all the major AI labs, top talent, world-class investors, and it is where the future is being built every day. That’s why, this December, we’re giving builders everywhere a chance to break in. We are taking over and launching Break In—a month-long hacker house program in the heart of San Francisco. If you’re not from SF, and you’re building an AI startup, this is your chance to join us. Build your startup on top of Dedalus’ Agents SDK or MCP deployment infrastructure and we’ll cover your stay (housing, lunch, and co-working space). As a member of Break In, you’ll get access to all the best parts of SF. You’ll be introduced to top founders, mentors, and investors. You’ll get to skip the line at the biggest tech events. Plus, you’ll receive free API credits and expanded access to the best-in-class AI stack through our partner network of top AI infrastructure companies. Applications open October 27th and close November 10th. We will be accepting applications on a rolling basis. Final acceptances will go out November 14th to ensure international founders have enough time to secure visas. Ready to break in? Follow us on Twitter/X for more updates and visit the link in the comments to apply on October 27th!

Cathy Di

109,650 görüntüleme • 10 ay önce

THIS IS A CALL TO EVERY MAN & WOMAN IN IRELAND... IT'S TIME! Will you answer Ireland's call at this pivotal turning point in our history? After Gardaí (and PSNI) ambushed the men who feed us? The men who deliver the goods we need? Men who we will have no food without? Men who work hard and are robbed blind? Like the rest of us are robbed? Men peacefully protesting to save their livelihoods and feed their children? Will you stand by after 14-year-old boys were pepper sprayed? After women were pushed over by those who swore to protect us? Will you condone tractors and trucks being seized even after peaceful protesters stepped down? Will you send a message that ambushing peaceful men in the middle of the night is not going to be tolerated? We all know something is JUST NOT RIGHT in Ireland (and in other EU countries). We all feel it in our gut. Our bones. Our souls. We see it in the cost of everything. We see it in our bare cupboards. We see it in our empty wallets. We see it at the fuel pumps. We see it in the house prices. We see it when we watch entire town loads of our young leave Ireland because they have no choice. We see it in government actions that never benefit us, but always benefit someone else. We see how our opinions and protestations are turned into attacks on our characters. We see wrongdoing all around us and the truth is we have been far too compliant for far too long. Ireland is a country with plentiful natural resources, all given away, all for greed. It is a great little country, for everyone other than us. For politicians friends. For data centres. Corporations and Globalists with agendas that will forever change the course of our country and the future of her people. The government, like many others, is actively attempting to decimate our farmers and more besides. Replace our food with lab grown meat, EU sanctioned cricket meal and massive industrial GMO corporate farming. There are bigger agendas at play and those we pay no longer serve us and we know they will send riot police for us too. Things are going to get bad. What had happened with our farmers and hauliers will not be an isolated event. There is no denying that. We can no longer sit at home and watch from the sidelines, and we are running out of time. Our children and grandchildren need us to get off our knees. Rise up. IT'S TIME TO GET MAD. It's time to say "I'M AS MAD AS HELL, AND I'M NOT GOING TO TAKE THIS ANYMORE!" #FuelProtest #NoConfidence

IrishInquiry

22,782 görüntüleme • 4 ay önce