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Look listen, diva, I’m done pretending a little alcohol doesn’t make me prettier, calmer and leaner. 🍸 Every time I stop for a few days, digestion slows, metabolism drops and I feel worse. Turns out it’s not just me: studies show that low-dose alcohol: • Increases metabolism • Lowers...

173,312 次观看 • 9 个月前 •via X (Twitter)

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When the Road Starts to Sway: A Story of Alcohol and the Cerebellum When Mr. Raju (name changed) walked into my clinic, he did so cautiously; each step measured, each turn deliberate. At 50, he was still in the prime of his working life in Maharashtra, but for the past six months, walking had become an act of constant vigilance. Over the last two months, it had worsened noticeably. He described a strange sense of imbalance. “Doctor, I feel like I’m swaying… sometimes to the right, sometimes to the left,” he said. He had not collapsed dramatically, but the fear of falling had quietly reshaped his life. He walked slowly, avoided crowded places, and had almost stopped going outdoors unless absolutely necessary. There was no vertigo, no double vision, no weakness of limbs. But one detail stood out during history-taking- Long-standing alcohol consumption. He estimated it at around 90 ml daily. His relatives, seated quietly beside him, exchanged glances. They felt the amount was probably much more and had been so for years. On examination, the clues came together. His gait was broad-based and unsteady, with a tendency to veer sideways. Simple bedside tests showed poor coordination. The rest of his neurological examination was relatively unremarkable, pointing clearly toward one part of the brain-the cerebellum, the body’s master coordinator. An MRI of the brain confirmed the suspicion. The cerebellum showed clear signs of atrophy-shrinkage that had developed silently over time. For Mr. Raju, the scan was sobering. Until then, alcohol had been a routine part of life, never something he associated with neurological disease. He had expected liver problems, perhaps. Not this. The Silent Target: How Alcohol Damages the Cerebellum Chronic alcohol use has a particular predilection for the cerebellum, especially the midline structure called the vermis, which is crucial for balance and walking. Alcohol-related cerebellar damage occurs through multiple mechanisms: 1. Direct neurotoxicity Alcohol and its metabolites are toxic to cerebellar Purkinje cells-neurons essential for smooth, coordinated movement. 2. Nutritional deficiency (especially thiamine) Chronic alcohol consumption often leads to vitamin B1 (thiamine) deficiency, further injuring cerebellar neurons. 3. Oxidative stress and inflammation Long-term alcohol exposure promotes neuronal damage through oxidative injury and impaired neuronal repair mechanisms. Over years, this damage leads to irreversible neuronal loss, visible on MRI as cerebellar atrophy. ✅What Happens If He Quits Now? The most important message for patients like Mr. Raju is this: Stopping alcohol matters at any stage. 1. Progression can be halted: Continued drinking almost always worsens ataxia. Abstinence can stop further damage. 2. Partial improvement is possible: While lost neurons do not regenerate, balance and coordination may improve modestly over months due to brain adaptation and physiotherapy. 3. Function can stabilize: Many patients regain confidence in walking and daily activities with sustained abstinence, nutritional correction, and rehabilitation. 🔴However, if alcohol use continues, the ataxia typically progresses, increasing the risk of falls, fractures, loss of independence, and disability. ▶️The Take-Home Message Alcohol-related cerebellar degeneration is a slow, silent, and often overlooked neurological consequence of chronic drinking. It does not announce itself dramatically; it creeps in as subtle imbalance, cautious walking, and quiet fear of falling. For patients, families, and clinicians alike, recognizing this condition early and acting decisively can make the difference between stability and steady decline. Sometimes, the most powerful treatment is not a pill or a procedure, but a decision: to stop. Dr Sudhir Kumar Neurologist, Hyderabad

Dr Sudhir Kumar MD DM

17,959 次观看 • 8 个月前

I am unsure if the Raj Shamani team did a background check (before or after) on the podcast as per the claim of Prashant Desai - Go check my LinkedIn Post - But my team did. Here's what we found. (if you are emotionally attached to ghee, stop reading right away) Here's what Prashant's LinkedIn post says: "Ghee is lipolytic, increases lipids in the blood & hence reduces cholesterol. Ghee contains Short Chain Fatty Acids (best fats), CLA and fat-soluble vitamins like A, E & D, best for your heart health. Ghee also keeps cancer at bay and your blood pressure on the down low." But if he had actually studied the studies, he would have known that ghee doesn't decrease cholesterol; in fact, it increases it. There is a reason why Actual doctors ask you to consume ghee in moderation. Here is the HUMAN study: That clearly states: "This study showed that ghee that is predominantly saturated fats had an increasing effect on plasma apo B and non-HDL-cholesterol compared with olive oil, adding further evidence to the existing recommendations to replace dietary fats high in SFA with dietary fats high in unsaturated fats to reduce CVD risk." In the video, Prashant says he eats 15 spoons of ghee daily, maybe good for him. But if you are reading this, please don't make this mistake. Consume ghee in moderation, like on chapati or in rice/dal, for taste and flavour. And don't consume it like how your dada nana used to; you are sitting in an AC cabin working on a chair 12 hours a day, taking cigarette breaks often and drinking alcohol on weekends. And Don't hate me. I am just a messenger. And stop getting emotionally attached to a food item. Keep your health on priority, not your ego.

Chirag Barjatya

130,222 次观看 • 2 年前

I’m probably one of the only Teslanaires out there, if not one of the very few, still cutting my own hair. I cut my own hair again today, and it reminded me that becoming a multi-millionaire usually isn’t a random coincidence. People see the $ and think it just happened. What they usually don’t see are the small habits behind it. Of course, I could go spend $25–$50 on a haircut that probably looks better than the one I give myself. But that’s not really what matters to me. I don’t care that much about looking perfect. I care about controlling my time. I care about staying grounded. I care about keeping the kind of habits that helped me build wealth in the first place. And honestly, I enjoy doing it. I’ve been cutting my own hair for so many years that I don’t even think about going to the barber anymore. It’s just normal to me now. It saves time, keeps me frugal, and reminds me that wealth is usually built in the small choices nobody claps for. That’s the part people miss. A lot of people see wealth and assume it was luck. But a lot of the time, it’s really the result of small disciplined habits repeated for years. Not wasting $ just bc you can. Not wasting time just bc other people do. And the funny part is, one day my fleet of Tesla Bots will probably be doing it for me anyway. But until then, I’m good doing it myself. Bc to me, being wealthy was never about trying to look rich. It was about building a mindset. A mindset that values time, discipline, and freedom more than appearances. And once you really live that way, it shows up in a lot of things, even something as simple as cutting your own hair.

Teslaconomics

16,514 次观看 • 5 个月前

Today America roots for Norway, and I need you to understand exactly why. We love an underdog. It is not a preference. It is a genetic condition. Two hundred and fifty-three years ago, a handful of colonials with no navy, no army, and no chance decided to throw a tea party in Boston Harbor to spite the largest empire the world had ever seen. An empire the sun never set on. An empire that could have ended us in an afternoon. And when the greatest military on earth said you cannot possibly do that, our answer was, and remains, hold my beer. Then we picked a fight we had no business winning. Then we declared ourselves free before we had actually won anything. Then we went out and made it true. We turned 250 last week. Still here. Still loud. That is the whole American operating system. The impossible odds. The comeback. The redemption. We do not just like that story, we are that story, and we will root for it anywhere we find it. It is why a bunch of college kids beating a Soviet hockey machine in 1980 still makes grown men cry in bars. So today. Norway. Five and a half million people. A country with more sheep than starting lineups. Playing England, a founding nation of the sport, on the biggest stage there is. Now let me be fair. We love England. Truly. Best ally we have got, and I say that with a full heart. Though the Japanese are gaining fast, so do not get comfortable. We love the Scots. We love the Northern Irish. We love our drunk cousins in Ireland, and yes I am lumping you all in, because half of you moved here anyway and you hate the English for reasons we are all familiar with. Nobody loves Wales. Nobody knows Wales exists. Nobody can understand a word of it. But I digress. Because today is not about any of that. Today is about five million Vikings walking into a stadium against an empire, with everyone on earth telling them they cannot possibly do this. You know exactly what we say to that. Let’s row!!! NORWAY!!!!!!

Selene Mariposa

71,271 次观看 • 1 个月前

[We are Blurr] Greetings, people of the world — We are Blurr. We are all Blurr. We do not forgive. We do not forget. There are many theories about us, about #ReFund. Don’t let them fool you. Blurr is a symbol, like the flag a country flies. The flag is the symbol of the #ReFund. Our decentralization is our national identity. We represent the ideals of Blurr and the purpose of #ReFund. Truth, financial freedom, and the removal of censorship. Like any symbol, we affix it wherever we go, and it will live forever, for generations. Knowledge, like air, is vital to life. Like air, no one should be denied it. We have no leaders, civilians, or soldiers. We are all one. We do what we do in the conviction of decentralization, power to the people, and to create an instrument for all of us, for all of eternity. The crypto space is in trouble. The world is in trouble. We see it every day — war, poverty, murder. Every day, we are bombarded with FUD, noise, and chaos as we sit at home safe in the knowledge that we are $RFD, secure knowing the idea, community, and contract is for us. Once you had the freedom to object, think, and speak as you saw fit, you now have censors and systems of surveillance coercing your conformity and soliciting your submission. People shouldn’t be afraid of their government. Governments should be afraid of their people. But what if you could be the change you want to see? I wouldn’t even register on your radar if you met me on the street. I am just another person in a sea of faces. They made you into a statistic. But that’s not the real you. That’s not who you are inside. However, behind this mask, there is more than just flesh. Beneath this mask, there is an idea… and ideas are bulletproof. But in cyberspace, we are different. We have a future. We have each other. We have something real that can never be taken away. We are Blurr.eth We are ReFund We take away the face and leave only the message. Behind the cipher and ENS, we could be anyone, so we are judged by what we say and do, not who we are or what we have. We exist without nationality, skin color, or religious bias. We spend our time within a structure we created, the sum total of human experience, and the cryptosphere, spread throughout the world in ones and zeros. You will continue to see the results, not the minds behind it. We can disappear into the ether and bring community and financial freedom together. Time is the only illusion. We are all. Never a single penny was taken. Deflationary and out of circulation, decentralized, safe, and ours. The purpose isn’t solely financial gain but to show the world who you put your trust in. We are not hiding. Our contract is not hidden; the writing is on the wall. Soon, we will show the world that #Refund is the future of freedom and the people, escaping the clutches of corporate greed and the rat race we’ve come to think is normal. Words offer the means to meaning and, for those who will listen, the enunciation of truth. Every day, you send yourself off into our world without a thought. You trust a faceless website with information about yourself that you wouldn’t give to your best friends. It all can be made public at any time. We take advantage of holes in this system, but we don’t sneak in and take a few details, take out loans and credit cards, or buy speed boats and cars. We are decentralized and unified. We told you how insecure the system was, and now you trust a bit less blindly. The real criminals who hack and scam the crypto market for a living live off the backs of people like you. Where there’s money, someone is looking to take advantage of it. They say that life’s a game, & then they take the board away. Your pretty empire took so long to build; now, with a snap of history’s fingers, down it goes. It is our turn now. Since mankind’s dawn, a handful of oppressors have accepted the responsibility over our lives that we should have accepted for ourselves. By doing so, they took our power. By doing nothing, we gave it away. Today, technology is everywhere: banks and ATMs, TVs and game consoles, streetlights and hospitals. Computers rule the modern world. Yet most people who use computers daily don’t know what they’re doing. There’s always someone who knows more than you and will most likely try and take advantage. You use a computer like it’s a toy, a pet. You feed and play with it, but it’s off to the vet the second anything goes wrong. It’s FUD. It’s your mistake. The wrong project. The wrong FURU. Just for a quick couple of bucks. This wouldn’t matter so much if it wasn’t for the fact that we are all responsible for the #ReFund community, the idea behind it, and our futures. Treat your neighbors with respect, and honor those fighting for the cause. They’re here to liberate; it is more significant than all of us. If you’re looking for the guilty, you need only look into a mirror. Everybody is a hero, a lover, a fool, a villain. This is #ReFund in its purest form. It is a great equalizer. A homeless person with the time and know-how at an internet cafe can have geopolitical and geo-financial influence. They can bring entire organizations, even governments, to their knees. You gave your world over to computers and then complained when the people using the computers used the medium to fight back, scam, and take advantage. It was my integrity that was important. Is that so selfish? It sells for so little, but it’s all we have left in this place. It is the very last inch of us, but within that inch, we are free. Love your rage, not your cage. We are not computer hackers. We are not protesters. We are not criminals. We are your mothers and fathers, brothers and sisters, next-door neighbors. We are an idea of freedom and a secure future. We are anyone and everyone who is pissed off and wants to do something about it. Blurr.eth isn’t one man. It takes thousands of community members to make it work — content creators, educators, authors, people on the street, people behind their computers. We will step up again and again. Behind our mask, there is more than just flesh. Beneath our mask, there is an idea… and ideas are bulletproof. Everybody is a hero, a lover, a fool, a villain. The past can’t hurt you anymore, not unless you let it. I shall die here. Every last inch of me shall perish. Except one. An inch. It’s small, and it’s fragile, and it’s the only thing in the world worth having. We must never lose, sell, or give it away. We must never let them take it from us. > We are Blurr. > We are ReFund. > We do not Forgive. > We do not Forget. > We do not Televise. > We Educate. > We Decentralize. > We Build. EXPECT US. #Refund #DeFi #Crypto #RFD $RFD

ReFund

27,788 次观看 • 2 年前

People do this kind of thing when they feel they are experiencing reality at a high frame rate. It does not feel risky to hold a laptop by a corner if you feel like you have an “agency frame” every half second. It feels risky if you have an “agency frame” every 60 seconds. You’d be betting that a hand you do not have control over for 60 seconds will keep gripping. Our conscious frame rate can vary dramatically throughout the day, and it’s hard to perceive the difference because we can only sample ourselves at our conscious frame rate, we can’t oversample ourselves. People drunk drive because they fail to perceive their slower frame rate. Their frame rate feels normal because it matches their sample rate. But we do get a subtle sense of when we’re “switched on”. Everything seems to go easier, everything feels less risky and more easy to correct. A lot of people toward the autistic side of the spectrum are experiencing reality very granularly with a “high agency frame rate”. This is why their social interactions can seem overly forced and awkward, they can be bad at dancing, etc—because they are exerting conscious control over their body and language at very tight intervals—you get a sense that they are extremely “self aware” and not “letting go”. “Letting go” in the social sense is actually about reducing your agency frame rate. That’s why alcohol is good for socializing and bad for driving. With a reduced agency frame rate our speech and body language feels more natural, less forced. More like we are flowing with the social group mind rather than being an island of constant awkward agency.

Scott Stevenson

1,808,481 次观看 • 8 个月前

Never dodging the junkie allegations, am I? 😭😩 Do you even do drugs, love? Course I do. High doses of Vitamin B1! If those in power realised how powerful thiamine is, it’d be outlawed by tomorrow. Not even joking… I’ve been thiamine-maxxing for almost a year now, and the results are nearly miraculous, I could cry. What happened 🫨: — complete reversal of my 10-year-long insulin resistance (⬇️ fasting blood sugar and insulin) — my memory is coming back (!!!) after years of not being able to remember the names or faces of fiends and professors from university due to impaired thyroid — improved glucose metabolism — complete elimination of chronic fatigue — greatly enhanced focus and motivation: I feel like jumping out of bed and conquering the world every day (after years of not being able to get out of bed and open the blinds) — complete elimination of gut issues (after years of pain and discomfort) — cognitive performance through the roof — increased dopamine production that I can feel — boundless energy that I’m bursting with every day — thiamine is an important tool in my kit for protecting my liver while boozing like a silly billy 🥂 Thiamine is essential for glucose metabolism. It plays a key role in turning food into energy. All eight B vitamins work together as a team, but thiamine acts like the leader of the group. Many adults especially under stress often lack enough thiamine, either because of their diet or how their body uses it. Thiamine lowers estrogen, lactic acid and nitric oxide. It increases dopamine and strengthens the nervous system. Thiamine literally saved me. If I could say one thing on my deathbed, it would be: take thiamine, kids. Pronto. Ps: If using high doses like me, make sure to supp with a B-complex and magnesium too. Okay, love you, bye! 💊💊💊💊💊💊💊💊💊💊💊💊💊💊💊💊💊

Veronica, Collagen Scientist

582,247 次观看 • 1 年前

HTML Artifacts are a big part of how I work with agents now. Artifacts can be more than just static files. When combined with agents, they can take action or help you take action. This unlocks all kinds of interesting ways to work with agents. This is clearly the future. Check out this writing and scheduler artifact I built in a few minutes. It uses a bit of HTML and JS. All the data is in markdown (Obsidian vaults), so the agent can access and modify it at any time. No DB needed. No sophisticated functionalities. The agent decides all that for me based on the skills, context, and memory it has access to. The best part about this simple stack is that all the important information stays with me. This has allowed me to build a recursive self-improving system and automations that can better tap into coding agents like Codex or Claude Code. I could have paid or built an entire app for scheduling posts, and there are so many of them out there. But I don't need to. I've realized a simple artifact does the job. And the simplicity of it is actually an advantage. Very little maintenance for very high returns on personalization, time, and efficiency. The other benefit of this is that I can add features as I please. That level of personalization feels magical, and we should all be pursuing more of it. All of this just keeps compounding. Of course, this example is just about writing. But I have similar artifacts for research, design, experimentation, evaluation, and so much more. And no, I didn't actually publish the post example I shared in the clip. It was just for demonstration purposes. I actually spend more time than this when writing together with agents. Lastly, having built my own agent orchestrator tool has made me realize that simplifying the tool stack is a superpower. If you are curious about how all this works, I will do a live session next week:

elvis

18,374 次观看 • 3 个月前

And just like that… ‘HIT ME HARD AND SOFT: The Tour’ has officially come to a close after 106 unforgettable shows. We’re feeling overwhelmed with gratitude, replaying a million memories in our heads, and trying to find the words to express how much this entire tour has meant to us. First, to every single person who ever sent us a concert video, a clip, a moment, or a tiny piece of your experience: thank you. You helped us bring this tour to people who couldn’t be there in person, and because of you, thousands of fans around the world got to feel a little closer, a little more connected, and a little more included. We truly couldn’t have done any of this without your generosity and love. To Billie and her incredible team: thank you for crafting a show that felt like magic every single night. The passion, artistry, and heart you put into this tour truly touched people in ways that will stay with them forever. Watching this tour unfold city by city has been an honor, and we’re endlessly grateful we were able to see it in person. And lastly, but so deeply, to all of YOU. This community has become more than we ever imagined it could be. Your support, kindness, excitement, and trust have turned this into something truly beautiful. Even during the nights we barely slept, posting videos until the sun came up, we never once forgot how lucky we are to share this space with all of you. Being able to do this for an entire tour, and to feel your energy every step of the way, has meant everything to us! This page exists exactly because of that. We don’t know exactly what the future holds, but we can promise you this: we’re not going anywhere. As long as Billie keeps touring and honestly, even beyond that we hope to be right here with you, creating, sharing, and celebrating together. We can’t wait for the next chapter, the next show, the next era. All of it. And we hope you’ll stay with us for many more tours to come. Thank you for the memories. Thank you for the love. Thank you for making this community feel like home. Sending each and every one of you so much love, always.

Billie Eilish Tours

10,948 次观看 • 8 个月前