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Mechanical forces pattern endocardial Notch activation via mTORC2-PKC pathway. #DevBio

11,666 views • 1 year ago •via X (Twitter)

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What seemed like an intractable problem is now possible: To design proteins with a specified nonlinear mechanical response, capturing complex folding and unfolding mechanisms in singe and few-shot computations. We present ForceGen, an end-to-end algorithm for de novo protein generation based on nonlinear mechanical unfolding responses. Rooted in the physics of protein mechanics, this generative strategy provides a powerful way to design new proteins rapidly, including exquisite and rapid predictions about their dynamical behavior. Proteins, like any other mechanical object, respond to forces in peculiar ways. Think of the different response you'd get from pulling on a steel cable versus pulling on a rubber band, or the difference between honey and glass. Now, we can design proteins with a set of desirable mechanical characteristics, with applications from health to sustainable plastics. The key to solving this problem was to integrate a protein language model with denoising diffusion methods, and using accurate atomistic-level physical simulation data to endow the model a first-principles understanding. ForceGen can solve both forward and inverse tasks: In the forward task, we can predict how stable a protein is, how it will unfold and what the forces involved are, all given just the sequence of amino acids. In the inverse task, we can design new proteins that meet complex nonlinear mechanical signature targets. Read the paper, led by LAMM@MIT postdoc Bo Ni, published in Science Advances: Why do we care about the mechanics of proteins? The mechanics of proteins are critical elements of many living systems - as evidenced in many studies of mechanobiology. Through evolution, nature has presented a set of remarkable protein materials with unique mechanical functions like elastins, silks, keratins or collagens that play crucial roles in biology. However, going beyond natural designs to discover proteins that meet specified mechanical properties remains challenging. So far, the only way to do this was to use existing evolutionary concepts or to manually alter proteins. With our new generative model we can directly design proteins to meet complex nonlinear mechanical property-design objectives. ForceGen leverages deep knowledge on protein sequences from a pretrained protein language model and maps mechanical unfolding responses to create proteins. Via full-atom molecular simulations for direct validation from physical and chemical principles, we demonstrate that the designed proteins are de novo, and fulfill the targeted mechanical properties, including unfolding energy and mechanical strength, and a detailed unfolding force-separation curves. ForceGen offers rapid pathways to explore the enormous mechanobiological protein sequence space unconstrained by biological synthesis, to enable the discovery of new protein materials with superior mechanical properties. B. Ni, D.L. Kaplan, M.J. Buehler, ForceGen: End-to-end de novo protein generation based on nonlinear mechanical unfolding responses using a language diffusion model. Sci. Adv. 10, eadl4000 (2024). DOI: 10.1126/sciadv.adl4000 Codes and model weights available Hugging Face: David Kaplan

Markus J. Buehler

47,269 views • 2 years ago

The best exercise for the brain you’ve probably never seen. According to Michael J. Lavery’s book “Whole Brain Power”, using a 4-pound sledge hammer to bounce a golf ball up and down dramatically amplifies both your neurological and physical demands Massive Central Nervous System (CNS) Activation The sheer weight of a 4-lb sledge forces the CNS to fire at a much higher intensity. To keep a lively golf ball bouncing on a heavy, rigid piece of steel, your brain has to send incredibly powerful, rapid-fire signals to your muscles. This level of resistance forces maximum motor unit recruitment, teaching your nervous system to fire more efficiently under tension. Elite Grip and Forearm Strength Lavery heavily emphasizes the link between hand/grip strength and brain health, viewing the hands as the direct external extension of the central nervous system. Bouncing a ball requires a loose, reactive wrist to absorb and redirect impact, but holding a 4-lb hammer requires immense isometric grip strength. Managing that weight leverages extreme stress onto the forearms, wrists, and fingers, building dense, functional grip strength that standard lifting rarely touches. Accelerated Neuroplasticity via Forced Focus With a light hammer, you can cheat the movement or rely on casual reflexes. With a 4-lb sledge, there is zero room for error. The high penalty for a missed bounce (the heavy hammer dropping or completely throwing off your rhythm) forces the brain into a state of hyper-vigilance and deep cognitive focus. This intense concentration triggers a higher release of acetylcholine and dopamine, the exact neurotransmitters required to stimulate neuroplasticity and forge new neural pathways. Overcoming Hemispheric Dominance (Ambidexterity) When you transition the 4-lb sledge to your non-dominant hand, the challenge scales exponentially. Because the non-dominant hemisphere of your brain isn't used to managing that much weight combined with fine motor precision, the drill forces rapid communication across the corpus callosum (the bridge connecting the left and right sides of the brain). It quickly exposes and corrects deep-seated muscular and neurological imbalances between your two sides. Cortical Mapping and Joint Stability Holding a heavy weight at the end of a lever arm requires all the stabilizing micro-muscles in your wrist, elbow, and shoulder rotator cuff to fire simultaneously. This builds incredible joint integrity while expanding your brain’s "cortical map"—its internal blueprint of where your body is in space (proprioception). Benefits: - Maximum Central Nervous System Recruitment - Dense Grip and Forearm Strength - Forced Cognitive Focus & Neuroplasticity - Rapid Dual-Hemisphere Brain Activation - Enhanced Proprioception & Joint Integrity - Growth Hormone (GH) and Testosterone - “ Fountain of Youth" Endorphins - Dopamine and Acetylcholine - Insulin Sensitivity and Blood Sugar Regulation

Thor Torrens

418,689 views • 4 months ago

How many times have you been told to “take it down a notch,” “calm down,” or “just relax” — while your heart races, your mind never powers down, and you live with a short fuse that embarrasses you later? You’re stuck in persistent fight-or-flight: anxious over small things, irritable, and unable to settle. The world blames you — “it’s just who you are,” try medication, manage it better. You’ve pointed fingers at people, money, family, politics, EMF, 5G, or blue light. You’ve tried therapy, breathing, supplements… yet the underlying tension always returns. This isn’t a mindset problem or personality flaw. It’s mechanical. The real culprit? Accumulated trauma — acquired, consecutive, and layered — creating a literal “vice-grip” compression on your central nervous system through your spine. Picture your nervous system as a perfectly solved Rubik’s Cube. The first major trauma adds the initial “turn,” misaligning the upper cervical spine (C1-C2). This compresses the brainstem, disrupts neural flow, cerebrospinal fluid, and electrical balance. Your entire spine immediately compensates with global adaptations — posture shifts, muscle contractions, even compensatory scoliosis — to protect the brainstem. Every new trauma stacks another layer on an already scrambled cube. These layers don’t reset; they compound dysfunction from a vulnerable position, tightening the vice grip and locking in deeper survival patterns. You become literally and figuratively wound up in chronic sympathetic dominance. This concept traces to the early 1900s with Dr. Richard VanRumpt’s pioneering work on layered subluxations. Yet most modern chiropractic treats the spine as something that simply “fell apart,” forcing alignment and hoping it holds. Without addressing the layered trauma and protective adaptations, results are temporary. The body reflexively returns to its survival pattern. The Stacking Effect produces stubborn symptoms: constant fight-or-flight, inhibited vagus nerve (poor digestion, inflammation, emotional dysregulation), and electrical dysfunction no willpower or medication can permanently fix. These aren’t “in your head” — they’re locked behind mechanical compression. The solution is precise and elegant. The YES Test (Your Electrical Systems Test) uses reflex analysis to “run the codes” on your nervous system, revealing the exact top layer — the most recent turn on your Rubik’s Cube. A highly gentle, vector-specific Master Reset then unlocks that layer. Often so subtle you barely feel it, yet the body responds immediately. Once released, your spine unwinds naturally — like a tightly twisted rubber band releasing twist by twist through normal daily movement. Layers clear in reverse chronological order. Compensatory patterns dissolve. Normal CNS communication returns. Homeostasis is restored. The process is elegant, automatic, and can be permanent (as long as no major new trauma occurs). I know this is true because I lived wired, anxious, and unable to relax for years — until this addressed the root mechanical cause. Hundreds upon hundreds of others (approximately 4,000 people) have experienced similar profound shifts. Your nervous system is electrical by design. Compressed wiring creates symptoms and dis-ease. Remove the compression at the source, and function, health, and true calm return. You don’t have to stay wound up. The constant fight-or-flight isn’t who you truly are — it’s simply the current mechanical state you’re stuck in. You can be solved. Your body is waiting to unwind. Link in next post

Dr. C ⭐️⭐️⭐️

43,596 views • 6 months ago

Shocking Covid-19 Hospital Protocols: Unvaccinated Patients Targeted for Deadly Treatments A disturbing pattern has emerged from hospitals across the U.S.—unvaccinated Covid-19 patients were subjected to aggressive, profit-driven protocols that often led to fatal outcomes. Dr. Brian Hooker reveals what patients and grieving families witnessed firsthand: 🔹 Vaccination Status Determined Care – The first question asked in hospitals wasn’t about symptoms, but “Are you vaccinated?” Unvaccinated patients were funneled into a dangerous, pre-set protocol with higher mortality rates. 🔹 Remdesivir: A Deadly Cash Cow – This failed Ebola drug (with questionable efficacy) was pushed aggressively. Why? Gilead Sciences and the NIH held the patent, meaning huge profits for hospitals via reimbursement. Studies showed organ failure risks, yet it remained the go-to treatment. 🔹 The Lethal Progression 1️⃣ Remdesivir → Kidney/liver damage 2️⃣ Oxygen (CPAP/BiPAP) → Further complications 3️⃣ Mechanical Ventilation → Often a death sentence 4️⃣ ICU Sedation Cocktails (Propofol, Fentanyl, Morphine) → Patients chemically restrained, sometimes in four-point restraints if they resisted. Result? Countless preventable deaths—families devastated, while hospitals profited at every step. “This wasn’t medicine—it was a business model built on desperation,” says Dr. Hooker. “Patients were denied early treatments (like ivermectin) in favor of a protocol designed to maximize billing, not healing.” The evidence is clear: We must investigate these deadly hospital protocols and hold those responsible accountable.

Camus

104,381 views • 1 year ago

Cable Zercher Slant Board Squat This is a very cool exercise I have started doing with the following beneficial mechanics: - Slant Board (Heels Elevated): The incline shifts your center of gravity forward, allowing for greater knee flexion, a deeper squat for those with limited mobility and a more upright torso. This puts an extreme emphasis on the quadriceps, particularly the vastus medialis (VMO) or teardrop muscle. - Zercher Position: Holding the load in the crooks of your elbows forces your upper back and core to work harder to prevent the weight from pulling your torso forward. This is a very natural force pattern that has great carryover to real life applications. - Safety/Stability: The cable acts as a guide, making it easier to maintain your balance on the slant board while focusing entirely on the muscle contraction, good for those who want to push the legs with a bit more “safety” than a free weight squat. Unlike a barbell where the tension changes through the range of motion (getting "easier" at the top), the cable provides constant mechanical tension throughout the entire squat. It is an exceptional movement for building teardrop quad definition and improving knee stability, as well as core bracing. I like to do it 6 or so sets, high volume repetitions - pyramiding up from low weight to high with minimal rest times - focusing on achieving the most brutal lactic acid build up that I can in the legs, done at the start of a workout. Even though the weight isn’t hugely high on the cable machine, it still packs a massive punch. Try it out! Wearing Sol Dept. 100% cotton sol shorts and drinking Aurum ancient mineral salts in my water

⚡️🌞 Sol Brah 🌞🐬

67,763 views • 9 months ago

Magnetohydrodynamic (MHD) Propulsion - What Is It?" by AsteronX #ufotwitter This video, titled "Magnetohydrodynamic (MHD) Propulsion - What Is It?" by AsteronX, explains the physics, operating principles, and potential applications of magnetohydrodynamic field propulsion for aerospace and spaceflight. 1. What is MHD Propulsion? [00:15] Magnetohydrodynamics (MHD) is the study of electrically conductive fluids—such as ionized gases, plasmas, or saltwater—interacting with magnetic fields [01:04]. MHD propulsion uses electromagnetic forces to accelerate conductive fluids directly, producing thrust without moving mechanical parts like propellers, turbines, or airfoils [02:29]. 2. Physical Mechanism: The Lorentz Force [02:47] Working Principle: When an electric current passes through a conductive fluid perpendicular to an applied magnetic field, it generates a perpendicular Lorentz Force [02:47]. Pressure & Acceleration: This magnetic force directly accelerates or decelerates the fluid particles, driving fluid flow and creating thrust or pressure gradients [08:30]. 3. Atmospheric Flight Mechanics [10:03] Air Ionization: Since neutral atmospheric air is non-conductive, the aircraft must ionize incoming air into a conductive sheath, often using high-frequency (radio/microwave) pulse discharges [10:19]. Aerodynamic Integration: The accelerated ionized air can be directed over specialized airfoils—such as saucer-shaped Coandă effect structures—to generate lift dynamically across the body [11:27]. 4. Space Application Concepts [12:20] Plasma Rocket Engines: Utilizing magnetic fields and Lorentz forces to accelerate cold or superheated plasma out of a nozzle without physical grid erosion [12:31]. Quantum Vacuum Thrusters (Theoretical): The video discusses futuristic concepts using ultra-short, intense electromagnetic pulses to interact directly with quantum vacuum virtual electron-positron fluctuations [13:35]. The core concept in the presenter's design is hull-integrated disc vehicle geometry, rather than an internal thruster, linear duct, or traditional rocket nozzle. In the video, AsteronX emphasizes that for magnetohydrodynamics (MHD) to be practical in atmospheric flight, the vehicle's physical shape and propulsion system must be unified into a single structure. Key Architectural Features of the Disc/Saucer Design 360° Coandă Effect Airfoil: Instead of pushing air through an internal engine tube, the saucer geometry acts as a continuous "wing wrapped around the vehicle". Plasma or ionized air accelerated across the curved upper skin adheres to the surface via the Coandă effect, generating low pressure and continuous lift across the entire hull. Surface Boundary Layer Sheath: High-frequency pulse discharge electrodes embedded along the outer skin ionize ambient air into a conductive plasma sheath surrounding the disc. The Lorentz force directly manipulates this sheath, eliminating aerodynamic drag, shockwaves, and thermal heating during flight. Field Drive vs. Mechanical Thruster: Rather than using discrete thruster pods or jet exhausts, magnetic and electric field arrays distributed across the disc's surface manipulate the fluid directly in 360 degrees, allowing omnidirectional maneuvering without moving parts or control surfaces. (This geometry directly builds on historical field-acceleration concepts, such as Jean-Pierre Petit’s MHD aerodyne and saucer research cited in the video description).

Alex

55,770 views • 22 days ago

It's quantum biorisonance fused with artificial intelligence-based diagnostics, scale frequency therapy, and zero-point field harmonies. Think of it as an MRI, an artificial intelligence-based surgeon, and a cellular regeneration system all rolled into one. HOW DOES THAT WORK? 1. FULL BODY QUANTUM SCAN Scan your biofield, the energetic model of your body Detects abnormalities at the subatomic level, long before symptoms appear Quantum sensors read your body like a hyper-dimensional fingerprint 2. TIME REVERSAL CELLPHONE •Tap into your original DNA pattern •Use field harmonies to "remind" your cells of their ideal state •It doesn't just heal, it restores 3. ZERO POINT ENERGY CAMP •It draws unlimited energy from quantum emptiness •Cells absorb this energy to accelerate repair and restore harmony •This is not "energy healing", this is quantum engineering of the fields 4. CORRECTION OF SCALAR FREQUENCY •Sends targeted scalar waves to reprogram damaged cells •Think of frequent acupuncture: no needles, just light and precision •Tumors, inflammation, scar tissue? •Neutralize yourself WHO CONTROLS THIS TECHNOLOGY? •Classified military medical programs •Independent scientific divisions •The same forces behind quantum finance, defense via artificial intelligence, and free energy. It's all connected. WHY NOW? Why the financial recovery, the boom of quantum computing, and the collapse of healthcare tech suppression are converging. They made fun of medbeds to make you laugh. But now they'll throw them like a miracle when the old world collapses. This is not science fiction. It's classified technology infiltrating public reality. The future is not about pills and surgery. It's about energy, frequency, and restoration of the original project. Follow 👉👉👉

Q(MEGA_TRUMP)

53,411 views • 1 year ago

(Phil Schneider + Ancient Knowledge + Modern Developments) If Phil Schneider was reporting what he believed to be true, and if ancient traditions were describing encounters as they understood them, how would the full picture look if it were internally consistent?🛸💫🐉👽🧠 Phil Schneider was not fundamentally saying “aliens secretly rule the world.” He was making a narrower and more destabilizing claim: Certain human institutions became aware of non-human intelligences or advanced technologies long ago, entered into secrecy-based arrangements, and reorganized power, infrastructure, and knowledge around classification rather than public legitimacy. The shift was not ideological, but structural: Power moved from shared authority → compartmentalized control. Connection to Ancient Traditions Across African, Egyptian, Sumerian, and Mesoamerican traditions, a consistent pattern appears: •Civilization is introduced, not invented •Knowledge comes from “others” (Nommo, Oannes, Chitauri, Serpent beings) •These beings are non-human, biologically distinct, often amphibious or subterranean •Authority is associated with anatomy: head shape, gaze, luminosity, longevity Hypothetically, ancient cultures preserved memories of encounters with advanced beings using the only frameworks available to them: myth, ritual, and anatomical symbolism. Why the Head shape, False Beard, and Anatomy Matters Cranial elongation, headdresses, and ritual beards become acts of imitation and lineage signaling. Credo Mutwa’s claim of a chin-growth or “beard” can be read as a remembered biological feature later reduced to symbolic regalia. Defacement of beards and facial features then reads not as vandalism, but as erasure of implication. Where Phil’s Underground Claims Fit Phil’s testimony introduces a modern continuation of the same pattern: •Non-human intelligences are not only “from the sky” •They are associated with subterranean environments •Some underground infrastructure is pre-existing •Advanced material science is involved •Presence is long-term, not episodic In this model, ancient “underworld” myths and serpent gods are not metaphors, but environmental descriptions filtered through mythic language. 5. Advanced Boring & Underground Bases Phil described tunneling that vitrifies rock, leaving glassy, sealed walls via non-mechanical excavation. Hypothetically, this could reflect: •Exposure to classified high-energy excavation research •Plasma or thermal boring concepts •Nuclear excavation studies (which historically existed) •Or partial repetition of briefings without full context The effects he described are real in physics. The interpretive leap is not the engineering — it is the attribution of non-human collaboration. Why This Resonates Today Governments now admit UAPs exist without explanation. Classified programs remain opaque. Whistleblowers are marginalized. Ancient cultures are being reassessed as more sophisticated than assumed. It feels like denial followed by partial admission — not confirmation, but resonance. Why Institutions Reject the Implications If humanity is not alone, civilization was externally influenced, and governments are not fully sovereign, then religious authority, political legitimacy, and public trust destabilize. Institutions respond with silence, reframing, delay, and minimization — not necessarily because of aliens, but because loss of control is unacceptable.

Jack

35,589 views • 8 months ago

Ask anyone who’s taken a course in Ordinary Differential Equations (ODEs) what a solution to an ODE represents geometrically, and most of them won’t have a clean answer. When I first took ordinary differential equations, the pattern was always the same. Early on it turns into a speedrun of methods: separation of variables, integrating factors, variation of parameters, Bernoulli, exact equations. Then pretty quickly the course slides into hammer-picking. Spot the form, apply the recipe, move on. Too mechanical! And the real problem is what you don’t walk away with. You leave with a toolkit, but without a feel for what a differential equation even is, especially geometrically. That matters because in real modeling the equations you meet are rarely nice enough to reward memorised recipes. So you get trained to solve toy forms, while the actual subject stays blurry. The behavior. The flow. The shape of solutions. It wasn't until I watched the first lecture of Professor Arthur Mattuck that I realized I didn’t actually know what a solution to a differential equation represents geometrically. His point is almost embarrassingly simple. A first-order ODE is a slope field, and a solution is a curve that stays tangent to that field everywhere. The math breakdown: Write the ODE as dy/dx = f(x,y). At each point (x,y), attach a tiny line segment with slope f(x,y). A function y = y₁(x) is a solution exactly when its graph follows those slopes. At every x, the slope of the curve equals the slope prescribed by the field at the point on the curve. That’s the one line that ties both viewpoints together: y₁′(x) = f(x, y₁(x)). So solving the ODE and drawing an integral curve are the same statement in two languages. Once you see that, you stop obsessing over whether you can write y(x) in closed form. You start asking the questions that actually matter. Where do solutions flow. Where do they get trapped. Where do they blow up. Where does existence or uniqueness fail because the field isn’t even defined? That’s the perspective shift I wish every ODE course forces early. It’s also why I keep pairing math with animation. #DifferentialEquations #ODEs #VectorFields #AppliedMathematics #Mathematics #

Mathelirium

40,841 views • 8 months ago

The Orbital Paradox: Gravity, Geometry, and the Biomechanics of the Self The persistent human self is a functional property of continuous biomechanical stabilization. A biological system must process spatial feedback faster than internal noise and gravity to maintain coherent perspective, this creates the orbital paradox. Standard computational models ignore physical weight, yet embodied geometric frameworks predict fragmentation of the spatial self-model once its inertial anchor is lost. Astronauts nevertheless remain coherent, showing how human architecture geometrically internalizes gravitational constraints. Dynamical closure occurs through the FVC loop (fascia, vestibular, cortex). The vestibular labyrinth uses otoliths to define a spherical volume of oriented space and supplies a zero-drift gravitational-vertical reference. The cortex issues rapid top-down predictive adjustments from this baseline. The fascial network serves as a slow, distributed mechanical sensor encoding continuous body-state tension and load. These nodes form a feed-forward circuit: vestibular anchor guides cortical prediction, which drives physical correction registered by fascia. Physical identity persists because the loop binds internal predictive maps to the body’s actual orientation under gravity. The body manages gravitational load through a tensegrity network whose axial skeleton settles into the lowest-energy configuration. This architecture converges on a dodecahedron whose 12 pentagonal faces saturate every proportion with the golden ratio φ. Over developmental time, long bones and joint angles scale to these φ constraints to minimize elastic energy. The dodecahedral attractor is the geometric solution the nervous system instantiates for physical coherence. Neurologists detect this 3D geometry via its 2D phase-space projection: a horizontal slice yields a regular decagon whose 10 vertices are cycled at 10 Hz, generating the cortical alpha rhythm. The somatic carrier integrates the geometry at 10 / φ ≈ 6.18 Hz (interoceptive theta). These channels superpose into a standing wave of amplitude 2 φ. The φ ratio—hardest for rationals to approximate, makes the self-model resistant to unstable harmonics amid metabolic noise. Subjective selfhood is successful inhabitation of this phase-locked node. Microtubules do not generate consciousness bottom-up. Macroscopic fascial tension applies mechanical pressure to the microtubular network, triggering the piezoelectric effect that converts physical shear into electrical body-state error signals the FVC loop requires. Anesthesia does not switch consciousness off; it scrambles microtubular synchronization until geometric decoherence occurs. This is downward causation: macroscale bodily architecture dictates microscale cellular coherence. The orbital paradox, how the gravitational loop survives microgravity, is resolved because the FVC loop and dodecahedral geometry develop under Earth’s constant load, establishing internal pre-stress within the tensegrity network. Removing external gravity does not erase shear forces stored in the fascia; otoliths retain their spherical reference and tissue preserves its φ proportions. Microtubular nodes continue firing in response to internalized structural shear. The standing wave, locked at the Diophantine φ ratio, remains robust without an external gravitational vector. The self therefore survives microgravity as a geometric attractor carrying the memory of gravity within its own architecture.

Erik Johnston

62,133 views • 3 months ago

SOMETHING BIG IS COMING: AMERICA'S LARGEST MIDEAST BUILDUP SINCE 2003 ACCELERATES NOW U.S. forces are executing a major transatlantic push that is visible to the entire world right now. Nine KC-46A Pegasus tankers have crossed the Strait of Gibraltar eastward from Lajes Field in the Azores, refueling and escorting roughly twelve Marine Corps F/A-18C/D Hornets from VMFA-312 “Checkerboards.” This is no isolated flight—it is the latest wave in the largest sustained U.S. military buildup in the Middle East since the 2003 Iraq invasion. THE TRANSIT DETAILS ➡️ The tankers operated under standard ADOBE callsigns used for long-range CORONET fighter transit missions. ➡️ They departed after staging at the critical mid-Atlantic hub of Lajes Field in Portugal’s Azores. ➡️ The Hornets belong to the elite VMFA-312 squadron based at MCAS Beaufort, South Carolina. THE FORWARD FORCE ALREADY IN PLACE ➡️ Dozens of additional U.S. refueling aircraft, both KC-46A Pegasus and KC-135 Stratotankers, sit ready at Israel’s Ben Gurion Airport. ➡️ Fighters including F-22 Raptors, F-15Es, and F-16s have already relocated to bases in Israel and Jordan. ➡️ Multiple carrier strike groups, such as USS Abraham Lincoln and USS Gerald R. Ford, provide a powerful two-carrier presence in theater. THE STRATEGIC REACH EXPANDING ➡️ Thousands more Marines are en route via amphibious ships and Marine Expeditionary Units toward the Gulf of Oman and Red Sea. ➡️ This air bridge multiplies U.S. capability for extended patrols and force projection deep into CENTCOM’s area. ➡️ The movement targets enhanced operations around the Persian Gulf, Strait of Hormuz, and Red Sea. THE BIGGER CONTEXT ➡️ The pattern has run nonstop since late January 2026 amid heightened tensions and operations involving Iran. ➡️ Everything remains fully observable in real time through open-source flight tracking and plane spotters. ➡️ This is sustained reinforcement at the highest posture levels seen in years. #USAirpowerSurge #MarineCheckerboards #MideastBuildup #KC46Tankers #CORONETMission #CENTCOMReinforcement #PersianGulfPosture

Mark

42,170 views • 6 months ago

AI discovered how a material just one atom thick can keep carrying load as its atomic structure begins to break, preventing catastrophic failure. This discovery is based on first-principles atomic scale reasoning integrated with biological principles, cutting across scales and providing deep insights into materials in extreme conditions. The resulting material is extremely lightweight yet strong, far better performing than existing structures. By organizing "simple" carbon atoms into hierarchical graphene architectures, unique materials can be designed that redistribute forces, accommodate deformation, and confine damage, the AI identified design principles for resisting catastrophic failure. The AI built the atomistic simulation instrument itself "from scratch"; and then conducted experiments autonomously that revealed when alignment strengthens a material, when hierarchy protects it, and when an apparently promising design fails. This is a frontier in designing matter at its ultimate thinness - controlling how mechanical failure unfolds through the organization of individual atoms. Here is what we did: ▶️ We asked an AI to build and use a scientific instrument. It wrote the force engine, structure generators, loading procedures, analysis tools, and experiment database. The independent campaign ran for multiple days without scientific intervention. ▶️ We required the instrument to pass physical and numerical tests. The implementation passed twenty validation tests and reproduced reference energies to approximately 10⁻¹³ eV per atom in the tested configurations. Every proposed design then faced the same reactive interatomic model. ▶️ We required predictions before results, creating a loop of world model building and falsification/verification. The AI had to commit to what unseen designs would do, then run the simulations. Incorrect predictions became opportunities to identify missing mechanisms. What emerged is a set of physical design principles: ▶️ The atom-scale arrangement of matter controls strength. The AI first showed how and why strength varied by more than sixfold across architectures. Similar amounts of carbon produced very different resistance to failure because they organized the load-bearing connections differently. ▶️ Rotating a pattern can change the mechanism of failure. Angled slit arrays revealed three regimes: neighboring slit tips link, intervening ligaments rotate, or short bridges bend. A rule based only on the remaining cross-section misses these changes in connectivity and motion. ▶️ Hierarchical structuring works under identifiable conditions. At the original scale, much of its apparent strength advantage can be explained by alignment. With greater separation between structural levels, selected hierarchical designs became about 25% stronger than same-mass single-level controls and showed larger integrated stress-strain responses. Veins redistribute load, compartments localize damage, and the architecture changes how cracks propagate. ▶️ A failed prediction is crucial to reveal the next experiment. Some proposed rules survived targeted tests; others failed. Longer loading preserved the broad architectural strength contrasts while revealing additional deformation and, in some cases, later stress peaks. The scientific value lies in identifying both the rule and its boundary as the AI punctures known scientific knowledge. ▶️ The instrument opens an extremely complex design space. The AI was able to expand the design languages into an open atlas of hundreds of thousands of atomically explicit structures. The deeper implication is that AI can construct an executable connection between equations, experiments, and explanations. Physical reasoning is something they can implement, interrogate, and revise. A scientific instrument extends what a scientist can observe; and an AI that builds such an instrument extends the experiments it can perform, and the questions it can ask, starting from basic principles of how atoms interact based on quantum mechanical ground truth. Models building models, with physical evidence shaping recursive reasoning loops.

Markus J. Buehler

392,298 views • 22 days ago

HERMES AGENT RUNS MONITORING, RESEARCH, LEAD DETECTION, AND COMPETITIVE ANALYSIS ON AUTOPILOT. AND KNOWS WHEN NOT TO SPEND YOUR TOKENS. the biggest unlock most people skip: Hermes cron jobs can decide ON THEIR OWN whether the LLM should wake up. WAKE AGENT — THE $0 GATE every cron job can run a Python script first. the script checks: did anything actually change? nothing changed: → script outputs {"wakeAgent": false} → LLM stays asleep → zero tokens spent something changed: → script outputs {"wakeAgent": true} → agent wakes up and handles it three gate patterns from official docs: → file-change: compare file mtime to last run. no change? sleep. → external-flag: another process drops a ready file. no flag? sleep. → HTTP-check: ping a URL, diff the response. same as last time? sleep. real example: monitor AWS costs every hour. script pulls current spend from AWS API. no spike? agent sleeps. zero cost. costs jump 40%? agent wakes, reports to Slack, takes action through Stripe MCP. you run 20 monitoring jobs a day. 18 of them find nothing. you pay for 2. NO AGENT — PURE SCRIPT, ZERO LLM some jobs don't need reasoning at all. TLS checks. uptime pings. disk alerts. heartbeats. hermes cron edit --no-agent --script check_health.py script runs. stdout goes straight to Telegram, Discord, or Slack. no LLM involved. flip any job between modes: hermes cron edit --agent # add LLM hermes cron edit --no-agent # remove LLM free monitoring that lives inside the same ecosystem as your agent. 4 MORE USE CASES THIS UNLOCKS: COMPETITIVE ANALYSIS weekly cron with script that diffs competitor pages. agent only analyzes actual changes. updates your tracking file and PRD skill automatically. PRD AS A SKILL save product requirements as a skill, not a document. skills load on demand into fresh context. documents drift. skills stay sharp. CONTENT REPURPOSING hand a video script to the agent. it drafts X and LinkedIn posts in your voice. writes to a review folder. you approve via Telegram. LEAD DETECTION webhook monitors inbox. agent spots potential leads. drafts responses using your business context. schedules meetings from your calendar. the pattern across all of these: scripts handle the mechanical work for free. the agent only spends tokens on reasoning that requires judgment. comment CRON and I'll send you 5 ready-to-paste cron configs with wakeAgent and no_agent patterns. full Hermes SOUL.MD guide 👇

YanXbt

96,224 views • 4 months ago

🚨 BREAKING: BILLIONS of allegedly Fake $GME Shares Just Hit a MASSIVE Settlement Wall! 🚨 They created the synthetics. Now, the structure is forcing them to answer for it. 🧵👇 🕵️‍♂️ THE PLAYERS: Ryan Cohen & the HoldCo. Diamond-handed, long-term holders. 💎👐 VS. Every Market Maker, Swap Desk, and Naked Short still sitting on a mountain of phantom paper. 🧻📉 🔥 THE PATTERN: The Game Has Changed Assume the premise: Billions of fake and naked GameStop shares were printed via market maker exemptions, FTDs, and shadow swaps. But under a true HoldCo? Checkmate. ♟️ Only DELIVERABLE shares can be tendered into the new parent company. ✅ Legitimate shares move upstairs into Teddy. 🧸 ❌ Synthetic positions cannot be delivered. The broker that printed them? They still owe. 💸 The Warrants = The Ultimate Filter. 🎟️ 59 MILLION $GMEWS become allocation tickets for actual holders. Synthetic equity does not automatically carry matching warrants. Real holders convert. The fakes do not follow on the same terms. They get left in the dust. 💨 📊 THE EVIDENCE IS IN PLAIN SIGHT Swaps referencing GameStop are staring down a massive Corporate Action Event. The underlying asset is changing as GameStop becomes an operating subsidiary. Counterparties MUST: 1️⃣ Settle 2️⃣ Terminate 3️⃣ Completely re-paper those contracts 📝 A clean HoldCo isolates the $20 BILLION credit line and brings outside capital to the parent level. Legacy synthetic counts that existed against the old float suddenly sit MISMATCHED against the new capital structure. How does a mismatch resolve? Delivery, cash settlement, or FORCED CLOSE-OUT. 💥 Look at the OCC: They’ve already shifted warrant settlement to broker-to-broker with written officer attestations and strict buy-in language. The infrastructure for non-standard resolution is ALREADY PLUGGED IN. 🔌⚡ 🛡️ THE WALL STREET COVERUP They’ll call it a "normal merger." 🤡 They’ll ignore the delivery crisis. 🙈 They’ll pretend synthetic shares can just roll forward forever. THE STRUCTURE DOES NOT ALLOW IT. Real shares move. Phantom paper collides head-on with a historic settlement event. 🧱🏎️💨 📅 THE CLIMAX The pressure cooker explodes the exact second the tender and warrant exchange opens. 🌋 👇 DO YOUR PART: 🔁 RETWEET this so every single holder sees the mechanical risk to the fakes! 💬 REPLY with how many real shares you actually hold! 🏷️ TAG the accounts still pretending synthetics are risk-free! (Credit the original HoldCo mapping masterclass to Goatbeardz 🐐) #GME #Teddy #NakedShorts #MOASS #GameStop #BBBYQ #MMTLP ⚠️ Entertainment purposes only • DYOR ⚠️

Eronima

15,157 views • 2 months ago