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Mitraclip Tweetorial Pt.2. Optimizing a perpendicular grasp. Getting off the aorta. I use this advanced steering technique in most Mitraclip cases. A perpendicular grasp allows for even bileaflet insertion without tension and clip canting on release.🧵 1/6 #UABStructural

36,517 views • 3 years ago •via X (Twitter)

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I just built my own wiki generator plugin for my agents. My agents can now generate wikis for anything I ask. One of my favorite wikis is called PaperWiki. This is a great example of what Andrej Karpathy describes. It uses obsidian vaults to organize papers, retrieve LLM-generated summaries, diagrams, and other advanced views for paper exploration. When Obsidian UI is not enough, I use my own artifact generator inside my agent orchestrator (see clip for example). This allows my agents to build any kind of view or exploration feature that I need. The papers are all curated with automations and several rules/patterns I have manually built over the years. On the surface, this looks basic. But behind the scenes, there are advanced search capabilities, connections, metadata, derived data, and other interesting bits of information that are extremely useful for my research agents. This is mostly built for agents. The artifact preview is just a high-level way to validate and quickly assess the quality of the wiki, suggest improvements, and it's also great for research. I use tobi lutke's qmd for all search capabilities. Everything is markdown. The summaries and even the diagrams. The wiki updates on its own based on several automations I have optimized over the past couple of weeks. The wiki grows and self-improves based on several requirements important for my research use cases. This is as personalized as it gets. There is nothing like it out there. And I use my research expertise to continue improving it over time. This is a vanilla wiki. There are so many things I want to build on top of this. Different aggregations, views, artifacts, etc. All to help automate more of my research work and accelerate productivity. I think the biggest leverage here is how powerful this could be for discovery and experimentation. One of my goals is to use it to find deeper connections and insights that would otherwise elude the top human researchers and use those to generate interesting new hypotheses and research experiments. That way, my agents can use autoresearch to explore research ideas at the frontier. Stay tuned for more.

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Do your nervous system a favor This looks ridiculous. The science is solid. When you inflate your cheeks fully, you create increased pressure inside your oral cavity and nasopharynx. That pressure pushes gently against the tissues that sit right alongside the vagus nerve as it passes through your throat and behind your palate. It’s a mild version of the Valsalva maneuver — the same technique ER doctors use to slow dangerously fast heart rates. You’re creating internal pressure that directly stimulates your vagus nerve without any equipment, any training, or any special technique. The slow release through barely parted lips extends the stimulation. As the air seeps out gradually, it creates a prolonged, gentle exhale — which is the single most effective breathing pattern for activating your parasympathetic nervous system. A longer exhale tells your brainstem to slow everything down. And the physical act of puffing your cheeks stretches the buccinator muscles in your face, which are almost always tensed during stress. When they stretch and then release, facial tension drops — and your brain reads a relaxed face as evidence of safety. Three things in one silly move: vagal stimulation, extended exhale, and facial tension release. Puff up. Hold 3-5 seconds. Release as slowly as possible. Do it 3 times. Your heart rate will be noticeably slower by the third one. Nobody said nervous system regulation had to look dignified.

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