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Natural engineering

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Nature is Amazing ☘️

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Airflow engineering meets natural design. Enjoy gaming with North Series.
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Airflow engineering meets natural design. Enjoy gaming with North Series.

Fractal Design

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So happy to see published our article in Nature Communications describing the first natural programmable metamaterial, demonstrating that biology uses engineering principles previously thought to be exclusive to humans. What is this? I will try to explain it...
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So happy to see published our article in Nature Communications describing the first natural programmable metamaterial, demonstrating that biology uses engineering principles previously thought to be exclusive to humans. What is this? I will try to explain it...

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Modern vessels are now using intelligent wind sails to harness natural airflow and reduce fuel consumption. It might look like a return to old sailing days but this is powered by advanced engineering- with automated systems that adjust to wind direction for maximum efficiency.
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Modern vessels are now using intelligent wind sails to harness natural airflow and reduce fuel consumption. It might look like a return to old sailing days but this is powered by advanced engineering- with automated systems that adjust to wind direction for maximum efficiency.

Science Simplified

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Dr. Bhupen Hazarika Setu Dhola Sadiya Bridge 🌉: 🇮🇳's longest, spanning over the Lohit River, linking Assam and Arunachal Pradesh. Discover the blend of engineering prowess and natural beauty in this architectural marvel. #DholaSadiyaBridge #PragatiKaHighway #GatiShakti #BuildingTheNation #ModiKiGuarantee Narendra Modi BJP Assam Pradesh BJP ArunachalPradesh BJP
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Dr. Bhupen Hazarika Setu Dhola Sadiya Bridge 🌉: 🇮🇳's longest, spanning over the Lohit River, linking Assam and Arunachal Pradesh. Discover the blend of engineering prowess and natural beauty in this architectural marvel. #DholaSadiyaBridge #PragatiKaHighway #GatiShakti #BuildingTheNation #ModiKiGuarantee Narendra Modi BJP Assam Pradesh BJP ArunachalPradesh BJP

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The Great Ziggurat of Ur has towered over the Iraqi desert for over 4,000 years. Sun-dried mud bricks, bound with natural bitumen (asphalt), reinforced with woven reed mats to stop cracking, one of the earliest examples of smart engineering in human history. Ancient builders were on another level. (clip by iggs89)
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The Great Ziggurat of Ur has towered over the Iraqi desert for over 4,000 years. Sun-dried mud bricks, bound with natural bitumen (asphalt), reinforced with woven reed mats to stop cracking, one of the earliest examples of smart engineering in human history. Ancient builders were on another level. (clip by iggs89)

Muse

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The Goliath Fungi of the Forest Floor 🍄🐌 Documenting the incredibly rare Goliath fungi in its natural habitat. From the perspective of a common garden snail, this magnificent structure must seem absolutely enormous. The intricate gill patterns and the sheer size of the stalk showcase nature’s incredible engineering in the damp undergrowth. A truly remarkable specimen to observe in the wild.
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The Goliath Fungi of the Forest Floor 🍄🐌 Documenting the incredibly rare Goliath fungi in its natural habitat. From the perspective of a common garden snail, this magnificent structure must seem absolutely enormous. The intricate gill patterns and the sheer size of the stalk showcase nature’s incredible engineering in the damp undergrowth. A truly remarkable specimen to observe in the wild.

Alexia👑

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🚨🌎🇬🇧 Climate Scam “Unfortunately the troubling reality that we face, is that this planets natural systems are rapidly approaching an irreversible tipping point” “Driven by unprecedented nature loss & climate change” Prince William doing his bit to perpetuate The Climate Scam. Notice how they never discuss ‘The Science’ or tell you Co2 = 0.04% of which humans contribute just 3% Nor do they wish to discuss the current Global Geo-Engineering efforts. What a Scam.
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🚨🌎🇬🇧 Climate Scam “Unfortunately the troubling reality that we face, is that this planets natural systems are rapidly approaching an irreversible tipping point” “Driven by unprecedented nature loss & climate change” Prince William doing his bit to perpetuate The Climate Scam. Notice how they never discuss ‘The Science’ or tell you Co2 = 0.04% of which humans contribute just 3% Nor do they wish to discuss the current Global Geo-Engineering efforts. What a Scam.

Concerned Citizen

258,627 görüntüleme • 1 yıl önce

Design Engineering Tip: Add friction at the end of a scroll interaction. When users reach the edge of a scrollable area, the movement should not just stop instantly. A subtle resistance, bounce, or slowdown can make the interface feel more physical and less mechanical. It helps users understand that they reached a boundary without needing extra labels or visual indicators. Used carefully, this can make scrolling feel more natural and closer to how objects behave in the real world.
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Design Engineering Tip: Add friction at the end of a scroll interaction. When users reach the edge of a scrollable area, the movement should not just stop instantly. A subtle resistance, bounce, or slowdown can make the interface feel more physical and less mechanical. It helps users understand that they reached a boundary without needing extra labels or visual indicators. Used carefully, this can make scrolling feel more natural and closer to how objects behave in the real world.

Gabriel

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Scientists at Cornell University have developed a “biohybrid” robot that moves in response to signals from the nervous system of fungi. These robots incorporate mycelium, the root system of fungi, which senses and communicates through electrical signals. Researchers grew mycelium directly into the robot's electronics, allowing it to drive the machine by processing these natural signals. The team built two versions: one with wheels and another spider-shaped with soft legs. Both versions respond to light and other stimuli, with the mycelium sending signals to the robot's actuators to initiate movement. Experiments demonstrated the robots' ability to move based on natural mycelium signals, react to ultraviolet light, and even allow manual override. Future developments may include multiple inputs like chemical signatures, enhancing the robot's ability to autonomously interact with its environment. Credit: Cornell University #engineering
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Scientists at Cornell University have developed a “biohybrid” robot that moves in response to signals from the nervous system of fungi. These robots incorporate mycelium, the root system of fungi, which senses and communicates through electrical signals. Researchers grew mycelium directly into the robot's electronics, allowing it to drive the machine by processing these natural signals. The team built two versions: one with wheels and another spider-shaped with soft legs. Both versions respond to light and other stimuli, with the mycelium sending signals to the robot's actuators to initiate movement. Experiments demonstrated the robots' ability to move based on natural mycelium signals, react to ultraviolet light, and even allow manual override. Future developments may include multiple inputs like chemical signatures, enhancing the robot's ability to autonomously interact with its environment. Credit: Cornell University #engineering

Wevolver

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Karpathy's Agentic Engineering finally has proper tooling! (built by Google) Karpathy defined agentic engineering as the discipline that separates production agent work from vibe coding. The core skills he listed were spec design, eval loops, and security oversight. The problem has been that practicing this still requires a different tool for every phase: - editor for code - a terminal for scaffolding - a browser for testing - a cloud console for deployment - and a separate framework for evals. Every transition is a context switch. The solution to production-grade Agentic Engineering is now actually implemented in Google’s Agents CLI. It covers the entire workflow in one place for scaffolding, evaluating, and deploying ADK agents. One setup command injects 7 ADK-specific skills into a coding agent's context, which lets it handle scaffolding, evals, deployment, and enterprise registration through natural language. I tested this end-to-end by building a RAG agent from scratch using Claude Code. It scaffolded the full project from the ADK agentic_rag template, generated 20 eval scenarios with LLM-as-judge scoring, and returned a quantitative scorecard. Finally, it also deployed everything to Agent Runtime and registered the agent to Gemini Enterprise, so the entire org can discover and use it. The video below shows this in action, and I worked with the Google Cloud team to put this together. Agents CLI GitHub repo → (don't forget to star it ⭐ ) I wrote up the full build covering all six steps from install to enterprise registration. It includes the eval scorecard, the instruction loophole the eval caught before deployment, and what the deployment process actually looks like end-to-end. Read it below.
0:15

Karpathy's Agentic Engineering finally has proper tooling! (built by Google) Karpathy defined agentic engineering as the discipline that separates production agent work from vibe coding. The core skills he listed were spec design, eval loops, and security oversight. The problem has been that practicing this still requires a different tool for every phase: - editor for code - a terminal for scaffolding - a browser for testing - a cloud console for deployment - and a separate framework for evals. Every transition is a context switch. The solution to production-grade Agentic Engineering is now actually implemented in Google’s Agents CLI. It covers the entire workflow in one place for scaffolding, evaluating, and deploying ADK agents. One setup command injects 7 ADK-specific skills into a coding agent's context, which lets it handle scaffolding, evals, deployment, and enterprise registration through natural language. I tested this end-to-end by building a RAG agent from scratch using Claude Code. It scaffolded the full project from the ADK agentic_rag template, generated 20 eval scenarios with LLM-as-judge scoring, and returned a quantitative scorecard. Finally, it also deployed everything to Agent Runtime and registered the agent to Gemini Enterprise, so the entire org can discover and use it. The video below shows this in action, and I worked with the Google Cloud team to put this together. Agents CLI GitHub repo → (don't forget to star it ⭐ ) I wrote up the full build covering all six steps from install to enterprise registration. It includes the eval scorecard, the instruction loophole the eval caught before deployment, and what the deployment process actually looks like end-to-end. Read it below.

Akshay 🚀

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One of the most common mistakes manufacturers make is relying on engineering logic to shape user behavior, while ignoring how users actually feel. Engineers often believe that as long as a feature exists, moves, or looks different, users will appreciate it. Users, however, care about something much simpler: whether the experience feels natural, refined, and intuitive. Great user experience is never created by stacking options. It is created by coherence and emotional consistency. Samsung’s recent update to Lock Star is a clear example. The new version introduces unlock animations that appear to add playfulness, yet the real experience feels disappointing. Many of these animations come across as childish, low level, poorly connected, and mechanically rigid. They feel closer to children’s UI effects than something designed for Samsung’s broad premium user base. The issue is not the presence of animations themselves. The problem lies in the mindset behind them. These effects are clearly driven by implementation logic rather than user perception. The assumption seems to be that adding visual flair automatically creates delight, while ignoring rhythm, emotional tone, and aesthetic maturity. This reflects a long standing pattern in Samsung’s software design. Random stickers, cartoon like emojis, and decorative elements often appear without a cohesive design language. There is a belief that younger users are attracted to these visuals, yet for Gen Z, such elements often feel outdated, immature, and disconnected from a premium identity. Strong product design allows user experience to constrain engineering decisions. When engineering begins to entertain itself, users quietly begin to disengage. Let's see how far apart Samsung and Xiaomi are.
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One of the most common mistakes manufacturers make is relying on engineering logic to shape user behavior, while ignoring how users actually feel. Engineers often believe that as long as a feature exists, moves, or looks different, users will appreciate it. Users, however, care about something much simpler: whether the experience feels natural, refined, and intuitive. Great user experience is never created by stacking options. It is created by coherence and emotional consistency. Samsung’s recent update to Lock Star is a clear example. The new version introduces unlock animations that appear to add playfulness, yet the real experience feels disappointing. Many of these animations come across as childish, low level, poorly connected, and mechanically rigid. They feel closer to children’s UI effects than something designed for Samsung’s broad premium user base. The issue is not the presence of animations themselves. The problem lies in the mindset behind them. These effects are clearly driven by implementation logic rather than user perception. The assumption seems to be that adding visual flair automatically creates delight, while ignoring rhythm, emotional tone, and aesthetic maturity. This reflects a long standing pattern in Samsung’s software design. Random stickers, cartoon like emojis, and decorative elements often appear without a cohesive design language. There is a belief that younger users are attracted to these visuals, yet for Gen Z, such elements often feel outdated, immature, and disconnected from a premium identity. Strong product design allows user experience to constrain engineering decisions. When engineering begins to entertain itself, users quietly begin to disengage. Let's see how far apart Samsung and Xiaomi are.

Ice Universe

59,669 görüntüleme • 6 ay önce

Web Scraping is dead. Web Agenting is here. Writing selectors (div > .class > span) breaks every time a site updates. Building custom bots for every new target is a waste of engineering hours. TinyFish turns the entire real-time web into a single API. Input: Natural Language ("Find availability for X"). Target: 1 or 100 URLs. Output: Structured JSON. This isn't a simulation. It visits the Real-Time Web. 1./ One API, Many Sites - Same contract whether you hit 1 URL or 50. You focus on the Goal (Business Logic). TinyFish handles the How (Navigation, Clicks, Inputs). 2./ Real Automation - It doesn't just "read." It interacts. It fills forms, navigates multi-step flows, and handles dynamic JS content. 3./ Production Ready - This is the same infrastructure used by large enterprises, now exposed as a clean developer primitive. Logs, error handling, and structured data are built-in. The web is finally a proper API.
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Web Scraping is dead. Web Agenting is here. Writing selectors (div > .class > span) breaks every time a site updates. Building custom bots for every new target is a waste of engineering hours. TinyFish turns the entire real-time web into a single API. Input: Natural Language ("Find availability for X"). Target: 1 or 100 URLs. Output: Structured JSON. This isn't a simulation. It visits the Real-Time Web. 1./ One API, Many Sites - Same contract whether you hit 1 URL or 50. You focus on the Goal (Business Logic). TinyFish handles the How (Navigation, Clicks, Inputs). 2./ Real Automation - It doesn't just "read." It interacts. It fills forms, navigates multi-step flows, and handles dynamic JS content. 3./ Production Ready - This is the same infrastructure used by large enterprises, now exposed as a clean developer primitive. Logs, error handling, and structured data are built-in. The web is finally a proper API.

Tech with Mak

119,568 görüntüleme • 5 ay önce

Big moment for text-to-speech. Qwen just open-sourced a text-to-speech model that lets you clone voices, design new ones, and control speech using natural language. Let me explain what I mean: You can literally tell it "speak in a cheerful tone with slight nervousness," and it actually does that. No complex audio engineering needed. What makes this special: - 3-second voice cloning - Covers 10 languages: English, German, French, and more - Latency as low as 97ms for real-time applications - Supports both streaming and non-streaming generation The model comes in two sizes (0.6B and 1.7B parameters), so you can pick based on your hardware and quality needs. Three modes to work with: 1. Custom Voice: Use pre-built premium voices with instruction-based style control 2. Voice Design: Describe the voice you want in plain English (or Chinese), and the model creates it 3. Voice Clone: Provide a 3-second reference audio and clone that voice The best part? It integrates with vLLM for production deployment and has a simple Python package you can pip install. I've shared a link to the GitHub repo in the next tweet.
0:17

Big moment for text-to-speech. Qwen just open-sourced a text-to-speech model that lets you clone voices, design new ones, and control speech using natural language. Let me explain what I mean: You can literally tell it "speak in a cheerful tone with slight nervousness," and it actually does that. No complex audio engineering needed. What makes this special: - 3-second voice cloning - Covers 10 languages: English, German, French, and more - Latency as low as 97ms for real-time applications - Supports both streaming and non-streaming generation The model comes in two sizes (0.6B and 1.7B parameters), so you can pick based on your hardware and quality needs. Three modes to work with: 1. Custom Voice: Use pre-built premium voices with instruction-based style control 2. Voice Design: Describe the voice you want in plain English (or Chinese), and the model creates it 3. Voice Clone: Provide a 3-second reference audio and clone that voice The best part? It integrates with vLLM for production deployment and has a simple Python package you can pip install. I've shared a link to the GitHub repo in the next tweet.

Akshay 🚀

31,249 görüntüleme • 5 ay önce

𝗖𝗿𝗶𝘁𝗶𝗰𝗮𝗹 𝗪𝗮𝘁𝗲𝗿 𝗦𝗵𝗼𝗿𝘁𝗮𝗴𝗲 𝗶𝗻 𝗗𝗲𝗿𝗮 𝗕𝘂𝗴𝘁𝗶 𝗦𝗽𝗮𝗿𝗸𝘀 𝗛𝘂𝗺𝗮𝗻𝗶𝘁𝗮𝗿𝗶𝗮𝗻 𝗖𝗿𝗶𝘀𝗶𝘀 𝘽𝙖𝙡𝙤𝙘𝙝 𝙔𝙖𝙠𝙟𝙚𝙝𝙩𝙞 𝘾𝙤𝙢𝙢𝙞𝙩𝙩𝙚𝙚 Pir Koh, a sub-tehsil of Dera Bugti in Balochistan, is currently facing a severe humanitarian crisis. Despite its proximity to Sui—home to one of Balochistan’s largest natural gas reserves—the region’s population of over 50,000 people is enduring a crippling shortage of drinking water. This devastating situation, worsened by extreme heat and chronic governmental neglect, has forced families to take to the streets in protest or abandon their ancestral homes in search of water. The continued failure of the Public Health Engineering Department (PHE) to provide a sustainable solution has placed tens of thousands of lives in immediate danger. This is not the result of a natural calamity—it is a man-made disaster caused by decades of state negligence. Despite being the electoral constituency of the current Chief Minister of Balochistan, Pir Koh remains parched and abandoned. Rather than prioritizing the urgent needs of his own community, the Chief Minister appears more concerned with advancing politicized narratives that vilify peaceful citizens. The people of Balochistan have long been denied their most basic rights. If they are not met with violence, they are left to die from thirst, medical neglect, or the breakdown of essential infrastructure. The water crisis in Pir Koh is not an isolated tragedy—it is part of a broader pattern of systemic discrimination and deliberate underdevelopment by the state. We urgently call on the United Nations, UNICEF, Amnesty International, and all relevant international humanitarian organizations to take immediate action in response to this man-made water crisis in Dera Bugti. The people of Pir Koh—and all of Balochistan—deserve access to water, dignity, and protection. The international community must not remain silent. United Nations Amnesty International United NationsHumanRights United NationsICEF Amnesty Internationalsasia
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𝗖𝗿𝗶𝘁𝗶𝗰𝗮𝗹 𝗪𝗮𝘁𝗲𝗿 𝗦𝗵𝗼𝗿𝘁𝗮𝗴𝗲 𝗶𝗻 𝗗𝗲𝗿𝗮 𝗕𝘂𝗴𝘁𝗶 𝗦𝗽𝗮𝗿𝗸𝘀 𝗛𝘂𝗺𝗮𝗻𝗶𝘁𝗮𝗿𝗶𝗮𝗻 𝗖𝗿𝗶𝘀𝗶𝘀 𝘽𝙖𝙡𝙤𝙘𝙝 𝙔𝙖𝙠𝙟𝙚𝙝𝙩𝙞 𝘾𝙤𝙢𝙢𝙞𝙩𝙩𝙚𝙚 Pir Koh, a sub-tehsil of Dera Bugti in Balochistan, is currently facing a severe humanitarian crisis. Despite its proximity to Sui—home to one of Balochistan’s largest natural gas reserves—the region’s population of over 50,000 people is enduring a crippling shortage of drinking water. This devastating situation, worsened by extreme heat and chronic governmental neglect, has forced families to take to the streets in protest or abandon their ancestral homes in search of water. The continued failure of the Public Health Engineering Department (PHE) to provide a sustainable solution has placed tens of thousands of lives in immediate danger. This is not the result of a natural calamity—it is a man-made disaster caused by decades of state negligence. Despite being the electoral constituency of the current Chief Minister of Balochistan, Pir Koh remains parched and abandoned. Rather than prioritizing the urgent needs of his own community, the Chief Minister appears more concerned with advancing politicized narratives that vilify peaceful citizens. The people of Balochistan have long been denied their most basic rights. If they are not met with violence, they are left to die from thirst, medical neglect, or the breakdown of essential infrastructure. The water crisis in Pir Koh is not an isolated tragedy—it is part of a broader pattern of systemic discrimination and deliberate underdevelopment by the state. We urgently call on the United Nations, UNICEF, Amnesty International, and all relevant international humanitarian organizations to take immediate action in response to this man-made water crisis in Dera Bugti. The people of Pir Koh—and all of Balochistan—deserve access to water, dignity, and protection. The international community must not remain silent. United Nations Amnesty International United NationsHumanRights United NationsICEF Amnesty Internationalsasia

Baloch Yakjehti Committee

10,923 görüntüleme • 1 yıl önce

When it comes to destination dining, some restaurants rely entirely on their menus to draw a crowd. But on the sun-bleached coast of Puglia, Italy, there is a venue where the setting itself is a masterpiece of natural engineering. Tucked into the historic winding streets of Polignano a Mare, Grotta Palazzese is a legendary cave restaurant perched dramatically inside a hollowed-out limestone cliff, delivering what is easily one of the most breathtaking and unforgettable dining experiences in all of Italy. The history of the cave is just as fascinating as its modern allure; local nobility used this exact marine cavern for exclusive banquets as far back as the 1700s. Today, stepping onto the dimly lit wooden dining terrace feels entirely surreal. The cavern wraps around the tables like a massive stone amphitheater, opening up to unobstructed, panoramic views of the deep blue Adriatic Sea. As you dine on elevated Mediterranean seafood, the sound of the tide echoing off the ancient cave walls creates an intoxicating, deeply romantic atmosphere. While it represents a significant financial splurge, it stands as an absolute rite of passage for travelers seeking the intersection of dramatic Italian geography and luxury gastronomy. 🎥 | IG
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When it comes to destination dining, some restaurants rely entirely on their menus to draw a crowd. But on the sun-bleached coast of Puglia, Italy, there is a venue where the setting itself is a masterpiece of natural engineering. Tucked into the historic winding streets of Polignano a Mare, Grotta Palazzese is a legendary cave restaurant perched dramatically inside a hollowed-out limestone cliff, delivering what is easily one of the most breathtaking and unforgettable dining experiences in all of Italy. The history of the cave is just as fascinating as its modern allure; local nobility used this exact marine cavern for exclusive banquets as far back as the 1700s. Today, stepping onto the dimly lit wooden dining terrace feels entirely surreal. The cavern wraps around the tables like a massive stone amphitheater, opening up to unobstructed, panoramic views of the deep blue Adriatic Sea. As you dine on elevated Mediterranean seafood, the sound of the tide echoing off the ancient cave walls creates an intoxicating, deeply romantic atmosphere. While it represents a significant financial splurge, it stands as an absolute rite of passage for travelers seeking the intersection of dramatic Italian geography and luxury gastronomy. 🎥 | IG

𝕏 Travels, Hotels and Resorts

67,927 görüntüleme • 1 ay önce

eXoZymes (eXoZymes) (Nasdaq: EXOZ) CEO Michael Heltzen was featured on Session 20 of the GeneCoda podcast Executive Insights for Life Sciences Innovators, in an episode titled “AI-enabled cell-free biomanufacturing and the future of enzyme engineering,” streamed live on YouTube on April 17. eXoZymes is a B2i Digital (B2i Digital) Featured Company. See their full profile at In the conversation, Heltzen discusses the company’s thesis that producing complex molecules outside living cells can enable greater control, scalability, and speed compared to traditional biologic manufacturing. The discussion also covers how AI is helping identify and optimize enzyme pathways, the strategic considerations involved in building a platform company in today’s capital environment, what differentiates cell-free systems from established synthetic biology approaches, and where cell-free biomanufacturing could create commercial impact across nutraceutical, pharmaceutical, and industrial markets. Watch or listen here: Separately, eXoZymes and Cayman Chemical were featured in a Springwise case study on how the two companies are rethinking chemical manufacturing. The piece focuses on eXoZymes’ work bringing enzyme pathways from biology into the world of chemistry, with Cayman Chemical helping to scale the approach. CCO Damien Perriman is featured in the article. See the eXoZymes summary: eXoZymes is a Los Angeles, California-based biotechnology company that has developed a biomanufacturing platform offering the tools and insights to design, engineer, control, and optimize nature’s own natural processes to produce highly valuable natural products via a commercially scalable, sustainable, and abundant alternative: exozymes. eXoZymes is led by an experienced management team including Michael Heltzen, CEO; Damien Perriman, CCO; Dr. Tyler Korman, CSO and Co-founder; Dr. Paul Opgenorth, VP of Development and Co-founder; Fouad Nawaz, VP of Finance; Lasse H. Görlitz, VP of Communications; and Amy Lunzer, Chief of Staff. Learn more about eXoZymes Inc. at For investor inquiries, visit and learn about other B2i Digital Featured Companies at Disclosure: David Shapiro, Chief Executive Officer of B2i Digital, personally purchased in the open market and currently owns shares of unrestricted EXOZ stock, in line with B2i Digital’s practice of investing alongside its Featured Companies. This post is not intended to solicit the sale of EXOZ or any security, and it is not intended to offer any opinion on EXOZ as an investment. Conduct your own research and consult with your own professional advisors prior to making any investment decisions. See the complete disclosure in the Risks and Disclosures section of
0:15

eXoZymes (eXoZymes) (Nasdaq: EXOZ) CEO Michael Heltzen was featured on Session 20 of the GeneCoda podcast Executive Insights for Life Sciences Innovators, in an episode titled “AI-enabled cell-free biomanufacturing and the future of enzyme engineering,” streamed live on YouTube on April 17. eXoZymes is a B2i Digital (B2i Digital) Featured Company. See their full profile at In the conversation, Heltzen discusses the company’s thesis that producing complex molecules outside living cells can enable greater control, scalability, and speed compared to traditional biologic manufacturing. The discussion also covers how AI is helping identify and optimize enzyme pathways, the strategic considerations involved in building a platform company in today’s capital environment, what differentiates cell-free systems from established synthetic biology approaches, and where cell-free biomanufacturing could create commercial impact across nutraceutical, pharmaceutical, and industrial markets. Watch or listen here: Separately, eXoZymes and Cayman Chemical were featured in a Springwise case study on how the two companies are rethinking chemical manufacturing. The piece focuses on eXoZymes’ work bringing enzyme pathways from biology into the world of chemistry, with Cayman Chemical helping to scale the approach. CCO Damien Perriman is featured in the article. See the eXoZymes summary: eXoZymes is a Los Angeles, California-based biotechnology company that has developed a biomanufacturing platform offering the tools and insights to design, engineer, control, and optimize nature’s own natural processes to produce highly valuable natural products via a commercially scalable, sustainable, and abundant alternative: exozymes. eXoZymes is led by an experienced management team including Michael Heltzen, CEO; Damien Perriman, CCO; Dr. Tyler Korman, CSO and Co-founder; Dr. Paul Opgenorth, VP of Development and Co-founder; Fouad Nawaz, VP of Finance; Lasse H. Görlitz, VP of Communications; and Amy Lunzer, Chief of Staff. Learn more about eXoZymes Inc. at For investor inquiries, visit and learn about other B2i Digital Featured Companies at Disclosure: David Shapiro, Chief Executive Officer of B2i Digital, personally purchased in the open market and currently owns shares of unrestricted EXOZ stock, in line with B2i Digital’s practice of investing alongside its Featured Companies. This post is not intended to solicit the sale of EXOZ or any security, and it is not intended to offer any opinion on EXOZ as an investment. Conduct your own research and consult with your own professional advisors prior to making any investment decisions. See the complete disclosure in the Risks and Disclosures section of

B2i Digital

70,350 görüntüleme • 3 ay önce

BREAKING 🚨Google’s quantum chip didn’t prove we live in a multiverse. It just proved the universe is one beautifully connected sea.🧨 Google’s latest quantum chip solved a problem in five minutes that would take a classical supercomputer 10 septillion years. Some physicists are calling it proof of a multiverse — the idea that every possible outcome branches into its own reality, so the chip is somehow “sampling” answers from parallel universes. Uniphics shows there is no need for any multiverse. Everything is made of spinning Gyrotrons whose waves propagate through one single ξM-field sea of unbound energy that fills all space. When the quantum chip sets up its qubits, those Gyrotrons create vast networks of perfectly coherent spin waves. Because the waves interfere across the entire sea at once, the chip can explore enormous numbers of possibilities simultaneously — not by jumping into other universes, but by letting the single connected field do what it always does: keep perfect harmony across its entire volume. The speed-up comes from the natural parallelism of spin-wave interference plus local time-flow variations (t_flow = k / E_d,total) that let dense regions of the chip run on slightly different clocks, giving the appearance of massive parallel computation without ever leaving our one deterministic universe. The same three pillars that explain gravity as a push and the cyclic cosmos also turn quantum computing into simple, single-universe physics. The universe isn’t splitting into trillions of realities every time a chip runs. It’s simply one sea singing in perfect harmony — and Google just learned a new note. How soon will quantum computing explode when we stop inventing multiverses and start engineering the single connected sea? A Theory of Everything should be able to answer everything. Uniphics Explained Simply PDF: Chapters 1–10 free:
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BREAKING 🚨Google’s quantum chip didn’t prove we live in a multiverse. It just proved the universe is one beautifully connected sea.🧨 Google’s latest quantum chip solved a problem in five minutes that would take a classical supercomputer 10 septillion years. Some physicists are calling it proof of a multiverse — the idea that every possible outcome branches into its own reality, so the chip is somehow “sampling” answers from parallel universes. Uniphics shows there is no need for any multiverse. Everything is made of spinning Gyrotrons whose waves propagate through one single ξM-field sea of unbound energy that fills all space. When the quantum chip sets up its qubits, those Gyrotrons create vast networks of perfectly coherent spin waves. Because the waves interfere across the entire sea at once, the chip can explore enormous numbers of possibilities simultaneously — not by jumping into other universes, but by letting the single connected field do what it always does: keep perfect harmony across its entire volume. The speed-up comes from the natural parallelism of spin-wave interference plus local time-flow variations (t_flow = k / E_d,total) that let dense regions of the chip run on slightly different clocks, giving the appearance of massive parallel computation without ever leaving our one deterministic universe. The same three pillars that explain gravity as a push and the cyclic cosmos also turn quantum computing into simple, single-universe physics. The universe isn’t splitting into trillions of realities every time a chip runs. It’s simply one sea singing in perfect harmony — and Google just learned a new note. How soon will quantum computing explode when we stop inventing multiverses and start engineering the single connected sea? A Theory of Everything should be able to answer everything. Uniphics Explained Simply PDF: Chapters 1–10 free:

Paul Maley

46,801 görüntüleme • 4 ay önce

Beauty should be a core pursuit of biotechnology. There should be companies and nonprofits that engineer organisms solely for the sake of crafting beautiful things. A few reasons why: 1/ Biotechnology has historically worked in reductionist ways, but many useful functions only emerge at the systems level. By engineering a systems-level outcome, like beauty, we will get much better at engineering organisms in predictable ways. When I say "reductionist," I mean that most useful things in biotechnology (drugs and tools) were discovered by stripping molecules from their natural contexts. Scientists collect organisms from soil or wherever and then study their molecules in isolation. This basic approach has yielded everything from rapamycin to antibiotics and CRISPR. This reductionism, though, means that that we know disturbingly little about how life actually works at a systems-level. My core argument is that, by studying beauty, we can remedy this. Beauty has persisted through tens of millions of years of evolution because it is functional; bright colors help attract pollinators to a plant, for example, which helps the plant breed. If evolution has created all of this beauty for functional reasons, then it stands to reason that by trying to create **new** forms of beauty, we'll be able to discover and understand how these systems-level functions work! Indeed, we may even be able to create entirely new functions that biology hasn't evolved yet. These functions will not possible to understand via isolated molecules or reductionism. Therefore, a company pursuing engineered beauty for the sake of beauty will probably make many fundamental discoveries about how organisms develop, interact, adapt to their surroundings, and so on. 2/ Beauty is a way to grow the field and bring more people into biotechnology. Nick Desnoyer’s flower design work, for example, has probably reached hundreds of thousands of people. The glowing plants from Light Bio, too, were featured in the mainstream press. You may not think that these examples are “important” for the universe relative to, say, an incrementally better cancer therapeutic, but there’s no question that they are way more popular to mainstream audiences and good, overall, for the field. 3/ The market is huge! Breeding is already widely used to engineer beauty, or at least to select for aesthetic preferences. Pugs are evolutionarily suboptimal, but they've been bred precisely to satisfy a certain aesthetic desire are now a multi-billion dollar industry. The Juliet Rose, developed via breeding over a 15-year period, debuted at the 2006 Chelsea Flower Show and is enormously profitable today. Why should deliberately engineered forms of beauty be any different? If you are building a biotech company or nonprofit that is pursuing beauty, please reach out! I’d love to help.
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Beauty should be a core pursuit of biotechnology. There should be companies and nonprofits that engineer organisms solely for the sake of crafting beautiful things. A few reasons why: 1/ Biotechnology has historically worked in reductionist ways, but many useful functions only emerge at the systems level. By engineering a systems-level outcome, like beauty, we will get much better at engineering organisms in predictable ways. When I say "reductionist," I mean that most useful things in biotechnology (drugs and tools) were discovered by stripping molecules from their natural contexts. Scientists collect organisms from soil or wherever and then study their molecules in isolation. This basic approach has yielded everything from rapamycin to antibiotics and CRISPR. This reductionism, though, means that that we know disturbingly little about how life actually works at a systems-level. My core argument is that, by studying beauty, we can remedy this. Beauty has persisted through tens of millions of years of evolution because it is functional; bright colors help attract pollinators to a plant, for example, which helps the plant breed. If evolution has created all of this beauty for functional reasons, then it stands to reason that by trying to create **new** forms of beauty, we'll be able to discover and understand how these systems-level functions work! Indeed, we may even be able to create entirely new functions that biology hasn't evolved yet. These functions will not possible to understand via isolated molecules or reductionism. Therefore, a company pursuing engineered beauty for the sake of beauty will probably make many fundamental discoveries about how organisms develop, interact, adapt to their surroundings, and so on. 2/ Beauty is a way to grow the field and bring more people into biotechnology. Nick Desnoyer’s flower design work, for example, has probably reached hundreds of thousands of people. The glowing plants from Light Bio, too, were featured in the mainstream press. You may not think that these examples are “important” for the universe relative to, say, an incrementally better cancer therapeutic, but there’s no question that they are way more popular to mainstream audiences and good, overall, for the field. 3/ The market is huge! Breeding is already widely used to engineer beauty, or at least to select for aesthetic preferences. Pugs are evolutionarily suboptimal, but they've been bred precisely to satisfy a certain aesthetic desire are now a multi-billion dollar industry. The Juliet Rose, developed via breeding over a 15-year period, debuted at the 2006 Chelsea Flower Show and is enormously profitable today. Why should deliberately engineered forms of beauty be any different? If you are building a biotech company or nonprofit that is pursuing beauty, please reach out! I’d love to help.

Niko McCarty.

18,291 görüntüleme • 2 ay önce

🚨SCIENCE NEWS🚨: We’re no longer pushing electrons around wires — we’re learning to whisper directly to the sea’s own spins.🧨 Scientists just figured out how to control magnetism at the atomic level by manipulating individual electron spin patterns and creating stable magnetic whirlpools called skyrmions. These tiny structures can store and move data with almost zero energy, promising faster computers, ultra-dense memory, and a fundamental shift from charge-based electronics to pure spin-based technology. Uniphics already sees this as natural behavior of the ξM-field sea. Every particle is a bound gyrotron made from exactly three spin quanta whose rotations create coherent waves. When those waves form stable, self-sustaining patterns (exactly like the skyrmions now being engineered), they minimize local bound energy density through the negentropy drive. The surrounding unbound energy in the sea always repels itself, so any local spin configuration is naturally stabilized or moved by tiny density gradients. No extra materials or high-power circuits are fundamentally required — the sea itself carries and preserves the information as propagating spin waves. Chrono-coils — three orthogonal toroidal rings with golden-ratio windings and Fibonacci pulsing — let us engineer controlled low-density regions right now, tuning the time flow and stabilizing these spin patterns even more efficiently while harvesting vacuum energy through negentropy relaxation. The same three pillars that flatten galactic rotation curves at 220 km/s without dark matter and thin the cosmos without dark energy also make atomic-scale spin engineering straightforward. We don’t have to invent new physics to build spintronics; we only have to work with the sea that is already doing it everywhere. How soon do you think computing changes when we stop fighting electrons and start sailing the sea’s own spin waves? A Theory of Everything should be able to answer everything. Uniphics Explained Simply PDF: Chapters 1–10 free: Grokipedia: Grok xAI Elon Musk #Uniphics #Spintronics #Skyrmions #TheoryOfEverything
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🚨SCIENCE NEWS🚨: We’re no longer pushing electrons around wires — we’re learning to whisper directly to the sea’s own spins.🧨 Scientists just figured out how to control magnetism at the atomic level by manipulating individual electron spin patterns and creating stable magnetic whirlpools called skyrmions. These tiny structures can store and move data with almost zero energy, promising faster computers, ultra-dense memory, and a fundamental shift from charge-based electronics to pure spin-based technology. Uniphics already sees this as natural behavior of the ξM-field sea. Every particle is a bound gyrotron made from exactly three spin quanta whose rotations create coherent waves. When those waves form stable, self-sustaining patterns (exactly like the skyrmions now being engineered), they minimize local bound energy density through the negentropy drive. The surrounding unbound energy in the sea always repels itself, so any local spin configuration is naturally stabilized or moved by tiny density gradients. No extra materials or high-power circuits are fundamentally required — the sea itself carries and preserves the information as propagating spin waves. Chrono-coils — three orthogonal toroidal rings with golden-ratio windings and Fibonacci pulsing — let us engineer controlled low-density regions right now, tuning the time flow and stabilizing these spin patterns even more efficiently while harvesting vacuum energy through negentropy relaxation. The same three pillars that flatten galactic rotation curves at 220 km/s without dark matter and thin the cosmos without dark energy also make atomic-scale spin engineering straightforward. We don’t have to invent new physics to build spintronics; we only have to work with the sea that is already doing it everywhere. How soon do you think computing changes when we stop fighting electrons and start sailing the sea’s own spin waves? A Theory of Everything should be able to answer everything. Uniphics Explained Simply PDF: Chapters 1–10 free: Grokipedia: Grok xAI Elon Musk #Uniphics #Spintronics #Skyrmions #TheoryOfEverything

Paul Maley

15,949 görüntüleme • 3 ay önce