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Our second book is now available for pre-order. 🎉 Embracing the book's technology theme, we did something special: We encoded the entire book into DNA & packaged it into stainless steel capsules, where it will live for tens of thousands of years. 1,000 copies were made... 🧵

103,054 views • 1 year ago •via X (Twitter)

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Niko McCarty 🧫's profile picture
Niko McCarty 🧫1 year ago

We worked with three companies to bring this project to life: 1. @catalogtechinc, a DNA computing company. 2. @imagene_biotech, a company specializing in robust and room-temperature storage solutions. 3. @plasmidsaurus, a quick turnaround DNA sequencing company.

Niko McCarty 🧫's profile picture
Niko McCarty 🧫1 year ago

In Boston, CATALOG converted the book's text into the As, Ts, Cs, and Gs of DNA. The book was encoded in 500k unique molecules, collectively stretching millions of bases (longer than a bacterial genome.) Just 1,000 copies were made.

Niko McCarty 🧫's profile picture
Niko McCarty 🧫1 year ago

The DNA was shipped all the way to France, where IMAGENE packaged it into laser-sealed, stainless steel capsules under an inert atmosphere. Devoid of air, humidity, and contaminants, the DNA in these capsules is expected to survive for tens of thousands of years without decay.

Niko McCarty 🧫's profile picture
Niko McCarty 🧫1 year ago

And finally, a DNA capsule was shipped to Plasmidsaurus, a DNA sequencing company in California. The capsule was opened upon arrival and the DNA inside was reconstituted in water. The DNA was then "read" using a nanopore device and uploaded to the Internet for all to enjoy.

Niko McCarty 🧫's profile picture
Niko McCarty 🧫1 year ago

You will soon be able to view the DNA sequence, and learn more about how the text was encoded into nucleic acids, on CATALOG's website. Check it out at Thank you to @jasonjoyride and his team at S3 for the amazing announcement video. They're the best!

Niko McCarty 🧫's profile picture
Niko McCarty 🧫1 year ago

Note that this is the first commercially-available book to be written in DNA and sold in both forms. But it's not the first book encoded in DNA. In 2012, @geochurch encoded his book, Regenesis, into DNA. But he never sold that DNA; customers could only buy the physical book.

Niko McCarty 🧫's profile picture
Niko McCarty 🧫1 year ago

Now we're changing that. You can buy our second book in both forms. When you order a DNA capsule, you also get a printed book. Pre-orders are now open. Orders will ship in February. Thanks to @AsimovBio for their immense support. Learn more at

Eric Koester's profile picture
Eric Koester2 years ago

Over the past 8 years, I've helped over 2,000 authors publish books. Want to know a secret? The same six writing frameworks are behind all our bestselling books

CRISPR AI's profile picture
CRISPR AI1 year ago

Would like to purchase some of these 🧑‍🔬 for science, for the community.

Jason Carman's profile picture
Jason Carman1 year ago

Thank you for including us in this project Niko :) And thank you for all that you're doing with Asimov!

BIO Protocol's profile picture
BIO Protocol1 year ago

Fascinating way of evolving traditional publishing into a molecular form. Could be huge for long and short-term data storage, with one gram of DNA able to store nearly 215 million GB of data

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