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Paracetamol, while commonly used, is not without risk. Excessive or prolonged use can lead to liver damage, disruption of gut microbiota, and may impact brain function, including mood regulation and emotional response. Always follow dosage guidelines and consult a healthcare professional before combining medications.

33,076 görüntüleme • 1 yıl önce •via X (Twitter)

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Use creatine to protect your brain from head injuries: Repeated head injuries can lead to second-impact syndrome, where a subsequent injury before full recovery causes rapid and potentially permanent brain damage. This is a significant risk for athletes, military, or anyone prone to traumatic brain injury (TBI) or concussions. But here's the good news: research has shown that creatine supplementation can help mitigate the damage caused by second-impact syndrome. In fact, studies have found that creatine depletion prior to additional impacts can worsen the damage to your brain. So, what should you do? If you do experience a head injury, it's essential to replenish your creatine stores as quickly as possible. Creatine monohydrate is a good option, as it's the most researched and widely used form in studies, and it's also one of the most affordable and available options. Creating a regular creatine supplementation routine can be beneficial for overall health and wellness, regardless of your risk level for head injuries. You can obtain creatine through both food sources and supplements. While it is possible to get creatine from food, particularly from meat sources (which contain around 400-600mg of creatine per 100g or 3.5oz serving), it can be challenging to achieve the high dosages needed through diet alone. Most studies on creatine monohydrate for brain injuries have used high dosages of around 20g per day, which is significantly higher than the typical dosages used for performance benefits. As a preventative measure, a daily dose of 5-10g may be sufficient for most people. However, if you know you'll be at risk of exposure to head impacts, you may want to increase your dosage to 20-30g per day for a week, split into multiple doses. Remember, the primary goal should always be to minimize the number of head impacts and injuries in the first place.

Andy Galpin, PhD

137,470 görüntüleme • 1 yıl önce

I do not know who the guy is on the podcast with Raj Shamani, but he is absolutely wrong. There seems to be a section of "health influencers" who fearmonger the public on "dangers of whey protein or protein supplementation." Ammonia production is not a side effect of whey protein metabolism, but is a normal metabolic product of any protein metabolism. Ammonia is natural, generated as a by-product of protein ingestion through the breakdown of amino acids. Of the amino acids, glutamate is the one that has maximal free ammonia generation. In normal healthy persons, excessive ammonia generation is handled by the body and it does not affect brain function. This is done via the "urea cycle" in the liver: In patients with liver disease such as acute liver failure or chronic liver failure, the excess ammonia cannot be cleared out by the weak/failing liver or utilized in the muscles (because of muscle loss in liver patients) and affects brain functioning, leading to a condition called hepatic encephalopathy. This does not happen if you are healthy and taking additional protein. In fact, animal meats are more ammonia generating than plant-based or dairy-based protein and in those chronic liver failure patients with recurrent or persistent ammonia related brain dysfunction, the dietary advise is to limit animal meats and include more or switch to dairy+plant-based protein to keep ammonia generation low. Whey protein and scoops of additional whey protein to target protein requirement is perfectly safe and does not affect brain function or make the person slow like what is discussed in this video. Even advanced cirrhosis patients are supplemented with whey based protein formulations to target additional protein requirements and improve quality of life and immune functions Eg: and I hope we develop a law to deport brain dead misinformation peddling sub-standard "health influencers," like this guy in suit.

TheLiverDoc™

241,731 görüntüleme • 2 yıl önce

ACETAMINOPHEN, Known As Tylenol & Paracetamol Is The Leading Cause Of Liver Failure. It Causes Non Alcoholic Fatty Liver Disease & Actually Dissolves Liver Tissue. Acetaminophen causes 50% of all liver failures & the most Liver transplants in the United States. One Tylenol does as much damage as 6 pints of beer. And when Tylenol & Alcohol consumption are combined, the damage is 20-30 times that, because they are accelerating each other. Don't combine high fructose corn syrup drinks or artificially sweetened diet drinks with Acetaminophen either. The combination accelerates liver damage. It only takes 4,000 mg of Acetaminophen in a 24 hour period to damage the liver. Overshooting 4,000 mg – isn't hard. One Tylenol extra strength pill contains 500 mg of Acetaminophen. If an individual takes two pills up to four times a day, that's 4,000 mg. Add a cold or cough medicine that includes Acetaminophen & you can easily exceed the limit & cause acute liver failure. 5 Damaging Effects From Acetaminophen: 1️⃣ Depletes Glutathione: This vital antioxidant protects your liver & cells. Acetaminophen depletes it, leaving you vulnerable to oxidative stress. 2️⃣ Damages the Liver: Overuse leads to liver toxicity, impairing your body’s ability to detox naturally. 3️⃣ Triggers Inflammation: By increasing harmful byproducts, it causes chronic inflammation in your body. 4️⃣ Harms Gut Health: Acetaminophen disturbs your gut microbiome, leading to imbalances that impact your immunity. It causes gut permeability & lowers good beneficial gut bacteria. 5️⃣ Impacts Hormonal Balance: Toxic buildup interferes with hormone regulation, throwing your body off balance.

Thrilla the Gorilla

29,872 görüntüleme • 9 ay önce

ACETAMINOPHEN, Known As Tylenol & Paracetamol Is The Leading Cause Of Liver Failure. It Causes Non Alcoholic Fatty Liver Disease & Actually Dissolves Liver Tissue. Acetaminophen causes 50% of all liver failures & the most Liver transplants in the United States. One Tylenol does as much damage as 6 pints of beer. And when Tylenol & Alcohol consumption are combined, the damage is 20-30 times that, because they are accelerating each other. Don't combine high fructose corn syrup drinks or artificially sweetened diet drinks with Acetaminophen either. The combination accelerates liver damage. It only takes 4,000 mg of Acetaminophen in a 24 hour period to damage the liver. Overshooting 4,000 mg – isn't hard. One Tylenol extra strength pill contains 500 mg of Acetaminophen. If an individual takes two pills up to four times a day, that's 4,000 mg. Add a cold or cough medicine that includes Acetaminophen & you can easily exceed the limit & cause acute liver failure. 5 Damaging Effects From Acetaminophen: 1️⃣ Depletes Glutathione: This vital antioxidant protects your liver & cells. Acetaminophen depletes it, leaving you vulnerable to oxidative stress. 2️⃣ Damages the Liver: Overuse leads to liver toxicity, impairing your body’s ability to detox naturally. 3️⃣ Triggers Inflammation: By increasing harmful byproducts, it causes chronic inflammation in your body. 4️⃣ Harms Gut Health: Acetaminophen disturbs your gut microbiome, leading to imbalances that impact your immunity. It causes gut permeability & lowers good beneficial gut bacteria. 5️⃣ Impacts Hormonal Balance: Toxic buildup interferes with hormone regulation, throwing your body off balance. 👇Acute Liver Failure From Acetaminophen👇 👇Acetaminophen Toxicity👇 Speaker: Siggi Clavien, Bio Liver Expert Podcast: Dave Asprey, Human Upgrade Podcast

Valerie Anne Smith

726,805 görüntüleme • 1 yıl önce

One cup of coffee before 4 pm? - total blunder. I do not know why so many people follow this guy on Instagram. Half his content is lame jokes featuring two imaginary people named Saravana Kumar and Arockiasamy and the rest of it is poorly researched, vaguely discussed medical content that misleads & misinforms and in many videos he just randomly throws jargons like "gut health" and "fasting." See this video for instance. Dr. Pal says coffee is not good for the liver because there is no "good evidence" for it. And talks about polysaccharides in coffee that gets converted to short chain fatty acids that improve gut health. He then finally suggests that one cup of coffee before 4PM is good enough and prevents "further adverse effects of coffee." This man is dangerously peddling misinformation on a well studied and documented dietary intervention that spans decades - and in the form of large scale epidemiological studies and metanalysis of such studies, featuring more than 600,000 patients across the world. First, coffee related polysaccharides DOES NOT improve "gut health" - this has been shown in multiple studies from 2007 to 2018. The change of polysaccharides in coffee to short chain fatty acids is negligible and the effect of that on gut bacteria is also not signficant. "The growth of bifidobacteria and lactobacilli (good bacteria) was not stimulated by coffee - "However, caffeine and chlorogenic acid partially improved the disrupted short-chain fatty acid profile in mice, although coffee had no effects." - It is not polysaccharides, but the polyenols in coffee that is beneficial for the liver. This is independent of caffeine content and hence decaff is also healthy option for the liver. See here: In 2016 and 2017 the Institute for Scientific Information on Coffee in association with the British Liver Trust published a report that concluded that: - Regularly drinking moderate amounts of coffee may prevent liver cancer – which was reviewed by WHO and confirmed this reduced risk after reviewing more than 1,000 studies in humans - Coffee also lowers the risk of other liver conditions including fibrosis (scar tissue that builds up within the liver) and cirrhosis - Drinking coffee can slow the progression of liver disease in some patients - Beneficial effects have been found however the coffee is prepared – filtered, instant and espresso See here: In 2021, A large epidemiological study based on data from the UK Biobank in 384,818 people showed that all coffee types decrease the risk of adverse clinical outcomes in chronic liver disease. See here: In 2022, a nationally representative study from the USA showed in 4510 subjects, 20 years and older showed that coffee intake was associated with lower liver stiffness (scarring). See here: In 2023, the Canadian Liver Foundation noted in their release that one cup of black coffee a day could lower the risk of chronic liver disease by 15 per cent. About three to four cups a day can reduce the risk to 71 per cent - so the recommendation is at least 3 cups of black coffee without sugar & milk daily. The experts said that: “The great thing is it doesn’t really matter what way the coffee’s prepared. It can be decaf; it can be caffeinated. It can also be drip, French press, espresso, filtered, (and) instant. All the ways (show) that black coffee is effective for liver health.” See here: The American Liver Foundation advises including coffee in your diet to improve clinical outcomes in patients with fatty liver disease. See here: To avoid reductions in total sleep time, the last cup of coffee (the third cup, ideally 150ml in Indian standard) should be consumed at least 8 hours prior to bedtime. See here: These are just scratching the surface of evidence on benefits of coffee on the liver. And there is lack of evidence? What the mind does not know, the eyes cannot see. One cup of coffee before 4 PM? So lame. What is worse than pseudoscientific garbage like Homeopathy? - Legit doctors without a scientific temperament who misinform consistently. A legit bigger pain in the a** than Ayurveda and Homeopathy. Disclosure: I do not own stocks in any coffee company and have no involvement with the coffee industry and do not receive payments or honorarium from coffee industry stakeholders.

TheLiverDoc™

668,293 görüntüleme • 2 yıl önce