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Patrick Collison says humanity has never cured a complex disease. Not cancer. Not Alzheimer’s. Not Type 1 diabetes. His Arc Institute is trying something new: Simulate biology with AI. Test interventions before touching the body. Build a virtual cell. Test hypotheses in code. If it works, biology becomes computable.

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1,096,216 次观看 • 1 年前 •via X (Twitter)

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10 条评论

vitrupo 的头像

vitrupo1 年前

Arc Institute co-founder and Stripe CEO Patrick Collison at Hard Fork Live:

Muse Modalities 的头像

Muse Modalities1 年前

All of this absolutely needs cyberspace-native physics⚛

Ant A 的头像

Ant A1 年前

ASI having 100% benchmark saturation in chemistry, biology, physics, engineering, etc. will happen.

Suyash Verma 的头像

Suyash Verma1 年前

Great work!

𝗝 𝟯 𝟯 𝗣 𝟰 | 𝗷𝟯𝟯𝗽𝟰.𝗲𝘁𝗵 的头像

𝗝 𝟯 𝟯 𝗣 𝟰 | 𝗷𝟯𝟯𝗽𝟰.𝗲𝘁𝗵1 年前

Moronic. We test stuff in cells all of the time and they produce amazing results. In mice, lose many. In human studies lose almost all. That’s why it’s hard - we can’t simulate humans. We don’t need to simulate cells. We can already just try stuff at high throughout.

TRUST-AI BY TWC 的头像

TRUST-AI BY TWC1 年前

It could well be that there’s simply more money to be made in “managing” long-term chronic disease than developing actual cures. Never underestimate mankind’s tendency towards inhumanity to maximise self-interest.

Alicorn 的头像

Alicorn1 年前

Telling the truth is hard for some people. IT wasn't hard you just rather invest in wars and black site projects and money systems than to focus on uplifting the very people you farm everyday under the Veil of we just couldn't figure it out.

Erik Espinosa-DeLoges 的头像

Erik Espinosa-DeLoges1 年前

Yes, this was one of the original (futurist) claims--that AGI would be able to run simulations, and run them rapidly, without having to use any human test subjects, or even animals. AGI will also be able to map each persons body/biology, and create specific/detailed resolutions

Sean X. Luo MD PhD 的头像

Sean X. Luo MD PhD1 年前

Completely false. About 30% of stage iv melanoma is now cured. The recent trial of stem cells for DM1 was quite impressive.

Adan Z Becerra, PhD 的头像

Adan Z Becerra, PhD1 年前

Many curative treatments exist for cancer

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Patrick Collison on what changes when biology becomes programmable: "We, humanity, have never cured a complex disease." "Most cardiovascular disease, most cancers, most autoimmune disease, most neurodegenerative disease... For none of them can we really say that we've cured it, that we understand the causal pathways in meaningful detail." "Then over the last 10 ish years... we’ve gotten three new classes of technology in biology." "If you put those together, you now have the ability… to read, think, and to write. And this starts to really feel like a new kind of Turing loop." Patrick Collison with Michael Truell

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