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Pharmaceutical giants Moderna and Merck said Wednesday that their experimental cancer treatment showed signs of success in a study with high-risk melanoma patients. The first-of-its-kind treatment involves an mRNA vaccine that's tailored to individual patients and pairs it with a separate immunotherapy drug, Keytruda. The combination was effective in... show more

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Merck and Moderna announced Wednesday that a personalized mRNA-based cancer vaccine succeeded in a large, late-stage trial among high-risk patients who had melanoma — a dangerous type of skin cancer. The individualized vaccine, when paired with the existing immunotherapy, Keytruda, is the first and only combination regimen that demonstrated success in potentially extending melanoma patients' lifespans. The complete data set has not been made public or submitted to regulators for approval yet, but the initial results appear promising. Read more:

Merck and Moderna announced Wednesday that a personalized mRNA-based cancer vaccine succeeded in a large, late-stage trial among high-risk patients who had melanoma — a dangerous type of skin cancer. The individualized vaccine, when paired with the existing immunotherapy, Keytruda, is the first and only combination regimen that demonstrated success in potentially extending melanoma patients' lifespans. The complete data set has not been made public or submitted to regulators for approval yet, but the initial results appear promising. Read more:

ABC News

46,856 Aufrufe • vor 16 Tagen

A new, experimental skin cancer vaccine by the US company Moderna has had positive results in a late-stage trial. The mRNA vaccine, given to patients already diagnosed with melanoma, was given in conjunction with an immunotherapy drug and was shown to reduce the spread and recurrence of melanoma. It boosted the share price of Moderna - famous for its COVID vaccine - by as much as 93%. #News #Channel4News #C4News #Vaccine #Cancer #Health

A new, experimental skin cancer vaccine by the US company Moderna has had positive results in a late-stage trial. The mRNA vaccine, given to patients already diagnosed with melanoma, was given in conjunction with an immunotherapy drug and was shown to reduce the spread and recurrence of melanoma. It boosted the share price of Moderna - famous for its COVID vaccine - by as much as 93%. #News #Channel4News #C4News #Vaccine #Cancer #Health

Channel 4 News

24,624 Aufrufe • vor 16 Tagen

Drug companies Moderna and Merck have released encouraging results from a vaccine trial that shows promise in the battle against Stage 3 and Stage 4 melanoma, the most serious type of skin cancer. Dr. Natalie Azar breaks down the findings.

Drug companies Moderna and Merck have released encouraging results from a vaccine trial that shows promise in the battle against Stage 3 and Stage 4 melanoma, the most serious type of skin cancer. Dr. Natalie Azar breaks down the findings.

TODAY

37,988 Aufrufe • vor 3 Jahren

Moderna and Merck said a personalized mRNA cancer vaccine reduced the risk of melanoma recurrence and spread in a late-stage trial, sending Moderna shares soaring as much as 160%

Moderna and Merck said a personalized mRNA cancer vaccine reduced the risk of melanoma recurrence and spread in a late-stage trial, sending Moderna shares soaring as much as 160%

Reuters

102,912 Aufrufe • vor 16 Tagen

Last month Moderna reported the first individualized cancer vaccine to pass a Phase 3. Moderna CEO Stéphane Bancel and a16z's Jorge Conde on what that actually means: The treatment works by sequencing a patient’s tumor and healthy cells, identifying the mutations relevant to their cancer, and encoding up to 34 of them into an mRNA specific to the individual. Rather than simply unleashing the immune system, the goal is to teach it what to recognize and attack. In this conversation, they unpack the engineering challenge of manufacturing a different medicine for every patient, how Moderna has brought the process down to roughly 42 days from biopsy to treatment, and what it would take to manufacture personalized medicines at scale. 00:00 Intro 02:35 A Phase 3 that beat the standard of care 06:00 Why today's immunotherapy fails 40% of patients 09:35 A vaccine for cancer you already have 11:20 Why mRNA worked where 1,000 trials failed 13:15 90% of cancer antigens are unique to you 16:35 Why this vaccine only gets better from here 21:00 The only thing Moderna needs is your DNA sequence 22:20 Why the first robot was intentionally inefficient 27:10 How the FDA approves a drug that's different every time 33:05 A cancer treatment with the side effects of a flu shot 33:30 Why pancreatic cancer is worth a risk 36:30 Rare liver disease next, then autoimmune YouTube: Moderna Jorge Conde

Last month Moderna reported the first individualized cancer vaccine to pass a Phase 3. Moderna CEO Stéphane Bancel and a16z's Jorge Conde on what that actually means: The treatment works by sequencing a patient’s tumor and healthy cells, identifying the mutations relevant to their cancer, and encoding up to 34 of them into an mRNA specific to the individual. Rather than simply unleashing the immune system, the goal is to teach it what to recognize and attack. In this conversation, they unpack the engineering challenge of manufacturing a different medicine for every patient, how Moderna has brought the process down to roughly 42 days from biopsy to treatment, and what it would take to manufacture personalized medicines at scale. 00:00 Intro 02:35 A Phase 3 that beat the standard of care 06:00 Why today's immunotherapy fails 40% of patients 09:35 A vaccine for cancer you already have 11:20 Why mRNA worked where 1,000 trials failed 13:15 90% of cancer antigens are unique to you 16:35 Why this vaccine only gets better from here 21:00 The only thing Moderna needs is your DNA sequence 22:20 Why the first robot was intentionally inefficient 27:10 How the FDA approves a drug that's different every time 33:05 A cancer treatment with the side effects of a flu shot 33:30 Why pancreatic cancer is worth a risk 36:30 Rare liver disease next, then autoimmune YouTube: Moderna Jorge Conde

a16z

68,597 Aufrufe • vor 2 Tagen

Shocking results, hope restored for cancer patients. Cancer vanished in 100% of the patients, after 6 months trial with a drug, dostarlimab, with no significant side effects, first time in history of cancer. Colorectal/rectal cancer the 5th commonest cancer in Africa, and usually by the time its diagnosed it would have spread throughout the body giving low survival rates with the traditional treatment.

Shocking results, hope restored for cancer patients. Cancer vanished in 100% of the patients, after 6 months trial with a drug, dostarlimab, with no significant side effects, first time in history of cancer. Colorectal/rectal cancer the 5th commonest cancer in Africa, and usually by the time its diagnosed it would have spread throughout the body giving low survival rates with the traditional treatment.

Dr. Misheck Ruwende

107,404 Aufrufe • vor 3 Jahren

"This isn't just a cancer therapy. This is a way of liberating people from the burden of having a disease that could come back and kill you." On World Cancer Day, medicine laureates James Allison and Tasuku Honjo share their personal experiences with cancer and the hope their remarkable cancer treatment - immunotherapy - gives to patients around the globe. #WorldCancerDay

"This isn't just a cancer therapy. This is a way of liberating people from the burden of having a disease that could come back and kill you." On World Cancer Day, medicine laureates James Allison and Tasuku Honjo share their personal experiences with cancer and the hope their remarkable cancer treatment - immunotherapy - gives to patients around the globe. #WorldCancerDay

The Nobel Prize

16,921 Aufrufe • vor 1 Jahr

Elliot is among the first in England to receive a personalised cancer vaccine as part of a trial aimed at helping cancer patients. If successful, these vaccines might one day prevent a patients cancer from returning or spreading. Find out more.

Elliot is among the first in England to receive a personalised cancer vaccine as part of a trial aimed at helping cancer patients. If successful, these vaccines might one day prevent a patients cancer from returning or spreading. Find out more.

NHS England

93,493 Aufrufe • vor 2 Jahren

Thank you Dyson Cancer Centre and RUH Bath 🏥 for all you do to provide cancer patients with the very best care. Today The Queen spent time with patients and families to hear about their ongoing treatment and the support they have received. 🏥 The Queen also met NHS staff, volunteers and clinicians at the centre to learn about their use of innovative technology. The new Dyson Cancer Centre, which opened in April, provides a nurturing and therapeutic environment. The centre also features a Macmillan Cancer Support Wellbeing Hub. ❤️‍🩹 Wishing the very best to all those continuing cancer treatment on their path to recovery.

Thank you Dyson Cancer Centre and RUH Bath 🏥 for all you do to provide cancer patients with the very best care. Today The Queen spent time with patients and families to hear about their ongoing treatment and the support they have received. 🏥 The Queen also met NHS staff, volunteers and clinicians at the centre to learn about their use of innovative technology. The new Dyson Cancer Centre, which opened in April, provides a nurturing and therapeutic environment. The centre also features a Macmillan Cancer Support Wellbeing Hub. ❤️‍🩹 Wishing the very best to all those continuing cancer treatment on their path to recovery.

The Royal Family

156,261 Aufrufe • vor 2 Jahren

Great to see Dr Joe Ladapo and Dr William Makis collaborating on the use of ivermectin/fenbendezole in cancer treatment. Studies that verify the astonishing findings of Dr Makis. Who is treating over 6000 patients with great success in early stages of cancer. Achieving remission or significant shrinkage in tumours. Even having some success with stage 4 cancers. The Fenbendazole study showing patients going from stage 4 to cancer free and remained so up to 3 years. ‘That’s why the research is so important so that we can prove these things that I’m seeing in my clinic.’

Great to see Dr Joe Ladapo and Dr William Makis collaborating on the use of ivermectin/fenbendezole in cancer treatment. Studies that verify the astonishing findings of Dr Makis. Who is treating over 6000 patients with great success in early stages of cancer. Achieving remission or significant shrinkage in tumours. Even having some success with stage 4 cancers. The Fenbendazole study showing patients going from stage 4 to cancer free and remained so up to 3 years. ‘That’s why the research is so important so that we can prove these things that I’m seeing in my clinic.’

Kat A 🌸

39,866 Aufrufe • vor 10 Monaten

#CancerCalculus: An ICIJ-led collaboration with 47 media partners in 37 countries reveals how Merck & Co. keeps the price of its lifesaving cancer drug Keytruda sky-high, locking out patients and squeezing health care systems worldwide.

#CancerCalculus: An ICIJ-led collaboration with 47 media partners in 37 countries reveals how Merck & Co. keeps the price of its lifesaving cancer drug Keytruda sky-high, locking out patients and squeezing health care systems worldwide.

ICIJ

25,474 Aufrufe • vor 4 Monaten

The Remarkable Cancer-Fighting Benefits of Ivermectin • “Ivermectin can actually kill cancer stem cells,” which are often resistant to chemotherapy. • “It can also reverse resistance that cancer cells develop to chemotherapy,” making treatments more effective. • “It makes cancer cells susceptible to radiation treatment as well. And so it’s a radiosensitizer.” • Patients are seeing “tumors shrinking down to almost nothing, liver metastases disappearing, [and] brain metastases disappearing.” “There are over 100 papers on the success of ivermectin and cancer,” but much of this research has been ignored because the drug is off-patent, meaning “no one’s going to make money on it.” Dr. Makis has treated over 1,000 patients using combinations of ivermectin, fenbendazole, and other therapies. Many of his patients, told by their doctors that there was “nothing they can do for them,” are now “cancer-free” or have their “cancer under control.” The success stories are undeniable, and the hope is spreading. MakisMD

The Remarkable Cancer-Fighting Benefits of Ivermectin • “Ivermectin can actually kill cancer stem cells,” which are often resistant to chemotherapy. • “It can also reverse resistance that cancer cells develop to chemotherapy,” making treatments more effective. • “It makes cancer cells susceptible to radiation treatment as well. And so it’s a radiosensitizer.” • Patients are seeing “tumors shrinking down to almost nothing, liver metastases disappearing, [and] brain metastases disappearing.” “There are over 100 papers on the success of ivermectin and cancer,” but much of this research has been ignored because the drug is off-patent, meaning “no one’s going to make money on it.” Dr. Makis has treated over 1,000 patients using combinations of ivermectin, fenbendazole, and other therapies. Many of his patients, told by their doctors that there was “nothing they can do for them,” are now “cancer-free” or have their “cancer under control.” The success stories are undeniable, and the hope is spreading. MakisMD

skymeds store | Online Ivermectin Pharmacy

5,142,525 Aufrufe • vor 1 Jahr

🚨 GAZA HEALTH CRISIS: THOUSANDS OF CANCER PATIENTS WITHOUT ACCESS TO CARE • Around 10,000 cancer patients in Gaza • Nearly 3,500 women diagnosed with breast cancer • Thousands of new cases emerging during the war Haneen Shamieh, a mother of four in her thirties, was diagnosed with breast cancer during the war and has been unable to access proper treatment due to severe medication shortages and the collapse of medical services. She warns that continued delays may lead to a mastectomy and is urgently appealing for permission to travel abroad for life-saving treatment. Gaza’s healthcare system is rapidly deteriorating, leaving patients with life-threatening conditions without access to care.

🚨 GAZA HEALTH CRISIS: THOUSANDS OF CANCER PATIENTS WITHOUT ACCESS TO CARE • Around 10,000 cancer patients in Gaza • Nearly 3,500 women diagnosed with breast cancer • Thousands of new cases emerging during the war Haneen Shamieh, a mother of four in her thirties, was diagnosed with breast cancer during the war and has been unable to access proper treatment due to severe medication shortages and the collapse of medical services. She warns that continued delays may lead to a mastectomy and is urgently appealing for permission to travel abroad for life-saving treatment. Gaza’s healthcare system is rapidly deteriorating, leaving patients with life-threatening conditions without access to care.

Gaza Notifications

11,383 Aufrufe • vor 3 Monaten

Reminder - Recent studies have found the synthetic mRNA (modified messenger RNA) code in tumor cells. Keep that in mind when listening to the latest propaganda piece about mRNA vaccines. Health: mRNA Covid vaccines may help fight cancer Preliminary research published in Nature suggests that COVID-19 vaccines, particularly Pfizer and Moderna, may offer unexpected benefits for cancer patients. People with advanced lung or skin cancer who received the vaccine within 100 days of starting immunotherapy lived significantly longer. Researchers found that the mRNA in the vaccines might enhance the immune system’s response to cancer treatments, independent of any virus-related effects. Source: FRANCE 24 English

Reminder - Recent studies have found the synthetic mRNA (modified messenger RNA) code in tumor cells. Keep that in mind when listening to the latest propaganda piece about mRNA vaccines. Health: mRNA Covid vaccines may help fight cancer Preliminary research published in Nature suggests that COVID-19 vaccines, particularly Pfizer and Moderna, may offer unexpected benefits for cancer patients. People with advanced lung or skin cancer who received the vaccine within 100 days of starting immunotherapy lived significantly longer. Researchers found that the mRNA in the vaccines might enhance the immune system’s response to cancer treatments, independent of any virus-related effects. Source: FRANCE 24 English

Camus

26,296 Aufrufe • vor 10 Monaten

A personal message: Five years ago, my younger brother was diagnosed with an aggressive form of brain cancer. While we’re incredibly grateful that he responded well to treatment, the sad reality is that too many families of pediatric cancer patients aren’t as lucky. Please take a moment to watch his video, and if you can, send a message to your state’s U.S. Senators to urge them to vote yes on the Mikaela Naylon Give Kids a Chance Act. This bipartisan legislation aims to expedite the process of developing new treatment options for pediatric patients by providing the FDA with the authority to compel pharmaceutical companies to study the efficacy of combination drug therapies in children. This will help increase survival rates while minimizing treatment-induced side effects, many of which are irreversible. In return, the companies can receive priority review vouchers, which is mutually beneficial to the pediatric patients as it makes new drugs available sooner. In addition to reaching out to your Senators, please share this with as many people as you can, and thank you for supporting kids like my brother. Kids V Cancer

A personal message: Five years ago, my younger brother was diagnosed with an aggressive form of brain cancer. While we’re incredibly grateful that he responded well to treatment, the sad reality is that too many families of pediatric cancer patients aren’t as lucky. Please take a moment to watch his video, and if you can, send a message to your state’s U.S. Senators to urge them to vote yes on the Mikaela Naylon Give Kids a Chance Act. This bipartisan legislation aims to expedite the process of developing new treatment options for pediatric patients by providing the FDA with the authority to compel pharmaceutical companies to study the efficacy of combination drug therapies in children. This will help increase survival rates while minimizing treatment-induced side effects, many of which are irreversible. In return, the companies can receive priority review vouchers, which is mutually beneficial to the pediatric patients as it makes new drugs available sooner. In addition to reaching out to your Senators, please share this with as many people as you can, and thank you for supporting kids like my brother. Kids V Cancer

Ryan Shenker

24,493 Aufrufe • vor 9 Monaten

Megyn Kelly sat down with Dr. Patrick Soon-Shiong to discuss his revolutionary cancer protocol—a treatment that has already extended lives by years for patients with terminal diagnoses, including the late Senator Harry Reid. The Science Behind the Breakthrough Dr. Soon-Shiong’s approach challenges conventional cancer treatments like chemotherapy and radiation, which destroy the immune system’s natural killer (NK) cells and T-cells—critical for fighting cancer. His BioStripe treatment works by rebuilding the immune system, even in patients who have exhausted all other options. Real Patients, Miraculous Results Merkel cell carcinoma (5th-line treatment): Complete remission—patient lived 6+ years and didn’t die from cancer. Bladder cancer: Patients still alive 10-11 years later. Triple-negative breast cancer: Multiple complete remissions. Metastatic pancreatic cancer: One patient disease-free after 5 years, now 6+ years and counting. FDA Roadblocks & Lost Time Despite undeniable success, Dr. Soon-Shiong faced years of resistance from regulators. In 2015, he proposed testing his method before chemo/radiation—but the FDA insisted on starting with end-stage patients. After 700,000 pages of submissions, approval finally came in late 2024. The Future: Beyond Cancer This treatment isn’t just for cancer—it’s showing promise against sepsis and severe infections. One recent case: A Valley Fever patient on a ventilator, given last rites—fully recovered after treatment. The Urgent Question Why is bureaucracy slowing down a therapy that could save millions? With pancreatic cancer, glioblastoma, and lung cancer patients still dying every day, how many more lives could have been saved if this had been fast-tracked?

Megyn Kelly sat down with Dr. Patrick Soon-Shiong to discuss his revolutionary cancer protocol—a treatment that has already extended lives by years for patients with terminal diagnoses, including the late Senator Harry Reid. The Science Behind the Breakthrough Dr. Soon-Shiong’s approach challenges conventional cancer treatments like chemotherapy and radiation, which destroy the immune system’s natural killer (NK) cells and T-cells—critical for fighting cancer. His BioStripe treatment works by rebuilding the immune system, even in patients who have exhausted all other options. Real Patients, Miraculous Results Merkel cell carcinoma (5th-line treatment): Complete remission—patient lived 6+ years and didn’t die from cancer. Bladder cancer: Patients still alive 10-11 years later. Triple-negative breast cancer: Multiple complete remissions. Metastatic pancreatic cancer: One patient disease-free after 5 years, now 6+ years and counting. FDA Roadblocks & Lost Time Despite undeniable success, Dr. Soon-Shiong faced years of resistance from regulators. In 2015, he proposed testing his method before chemo/radiation—but the FDA insisted on starting with end-stage patients. After 700,000 pages of submissions, approval finally came in late 2024. The Future: Beyond Cancer This treatment isn’t just for cancer—it’s showing promise against sepsis and severe infections. One recent case: A Valley Fever patient on a ventilator, given last rites—fully recovered after treatment. The Urgent Question Why is bureaucracy slowing down a therapy that could save millions? With pancreatic cancer, glioblastoma, and lung cancer patients still dying every day, how many more lives could have been saved if this had been fast-tracked?

Camus

615,893 Aufrufe • vor 1 Jahr

CANCER IS REAL BUSINESS Dr. Stanislaw Burzynski's unconventional cancer treatment has sparked intense debate. His Antineoplaston therapy has inspired hope in some, but the medical mainstream remains skeptical. Devotees see him as a visionary, while detractors dismiss him as a quack. The controversy raises important questions about the future of cancer treatment. Can conventional and alternative approaches find common ground? How can we balance innovation with rigor and oversight? The answers will have far-reaching implications for patients and the medical community. The debate around Dr. Stanislaw Burzynski's cancer treatment is complicated by the FDA's involvement. Critics argue that the agency's oversight has hindered Burzynski's efforts, citing instances of bureaucratic delays and stringent regulations that can slow down the approval process for new treatments. Some claim the FDA's stance is influenced by a preference for conventional therapies and pressure from the pharmaceutical industry, suggesting the agency's actions are more about protecting established interests than safeguarding patients. However, others believe the FDA is fulfilling its role of ensuring treatments meet high safety and efficacy standards. They assert that Burzynski's methods have yet to be convincingly validated and express concerns about potential risks associated with his treatment. The reality may be somewhere in the middle. While the FDA aims to protect patients, its approach can sometimes be perceived as overly strict. Finding a balance between promoting innovation and maintaining robust oversight is key to offering patients safe, effective cancer treatments while also fostering progress in medical research.

CANCER IS REAL BUSINESS Dr. Stanislaw Burzynski's unconventional cancer treatment has sparked intense debate. His Antineoplaston therapy has inspired hope in some, but the medical mainstream remains skeptical. Devotees see him as a visionary, while detractors dismiss him as a quack. The controversy raises important questions about the future of cancer treatment. Can conventional and alternative approaches find common ground? How can we balance innovation with rigor and oversight? The answers will have far-reaching implications for patients and the medical community. The debate around Dr. Stanislaw Burzynski's cancer treatment is complicated by the FDA's involvement. Critics argue that the agency's oversight has hindered Burzynski's efforts, citing instances of bureaucratic delays and stringent regulations that can slow down the approval process for new treatments. Some claim the FDA's stance is influenced by a preference for conventional therapies and pressure from the pharmaceutical industry, suggesting the agency's actions are more about protecting established interests than safeguarding patients. However, others believe the FDA is fulfilling its role of ensuring treatments meet high safety and efficacy standards. They assert that Burzynski's methods have yet to be convincingly validated and express concerns about potential risks associated with his treatment. The reality may be somewhere in the middle. While the FDA aims to protect patients, its approach can sometimes be perceived as overly strict. Finding a balance between promoting innovation and maintaining robust oversight is key to offering patients safe, effective cancer treatments while also fostering progress in medical research.

Teaᡣ𐭩

125,284 Aufrufe • vor 2 Jahren

Hey, I'm Dr. Jason Williams, Director of Interventional Oncology and Immunotherapy at Williams Cancer Institute, and the foundation of everything I do comes down to one idea: the immune system is the answer. The standard approach to cancer - cut, poison, burn - wasn't designed with the patient in mind. That's why at Williams Cancer Institute, we go directly into tumors with immunotherapy instead of using systemic treatments that damage the whole body. We use off-label drugs and research that challenges conventional thinking and treatment approaches. Listen to the clip below from our first X Space where I talked more about our approach to cancer treatment at Williams Cancer Institute.

Hey, I'm Dr. Jason Williams, Director of Interventional Oncology and Immunotherapy at Williams Cancer Institute, and the foundation of everything I do comes down to one idea: the immune system is the answer. The standard approach to cancer - cut, poison, burn - wasn't designed with the patient in mind. That's why at Williams Cancer Institute, we go directly into tumors with immunotherapy instead of using systemic treatments that damage the whole body. We use off-label drugs and research that challenges conventional thinking and treatment approaches. Listen to the clip below from our first X Space where I talked more about our approach to cancer treatment at Williams Cancer Institute.

Jason R. Williams, MD, DABR

19,850 Aufrufe • vor 9 Monaten

Families of suspected Ebola patients in the DRC stormed a quarantine site where their relatives were receiving treatment, reportedly removing patients from the facility. It happened minutes after the health minister visited and has raised fears over the risk of transmission.

Families of suspected Ebola patients in the DRC stormed a quarantine site where their relatives were receiving treatment, reportedly removing patients from the facility. It happened minutes after the health minister visited and has raised fears over the risk of transmission.

Al Jazeera English

46,099 Aufrufe • vor 2 Monaten