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Polygenics and Machine SuperIntelligence; Billionaires, Philo-semitism, and Chosen Embryos – Manifold #102 This is a two-part episode. The first ~30m covers the most important 2025 breakthroughs in polygenic embryo screening, while the second 30m focuses specifically on AI capabilities at the frontier of human knowledge. Both segments make predictions...

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steve hsu

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a16z

195,623 Aufrufe • vor 8 Monaten

The Delta of Intelligence is Human Data! Curtis G. Northcutt is Director of AI Research at Handshake AI. In this episode, Curtis shares his unique perspectives on human data, RL envs, four quadrants of the AI market, journey of Handshake and much more. 0:00:00 - INTRO 0:02:08 - The Snowman Effect: From Rural Kentucky to 7 Years at MIT 0:09:50 - Confident Learning, Two Systems of Intelligence, Classical ML Has to Prevail 0:20:37 - Origin of CleanLab and Handshake acquisition 0:28:00 - How does GPT-5 become GPT-6? 0:31:20 - The Fastest growing Data Lab: What makes Handshake different? 0:35:32 - Difference between Good Data and Bad Data 0:38:17 - New kind of Data, IA and AI 0:42:04 - Scaling Coding Benchmarks and Efficiency in Long Horizon Tasks 0:49:12 - On Pre-Training, Misconception around Human Data 0:57:13 - Open Question: Taste and Personality, Quick Fire 01:05:15 - Advice to 20yo : Skill and Obsession
1:08:18

The Delta of Intelligence is Human Data! Curtis G. Northcutt is Director of AI Research at Handshake AI. In this episode, Curtis shares his unique perspectives on human data, RL envs, four quadrants of the AI market, journey of Handshake and much more. 0:00:00 - INTRO 0:02:08 - The Snowman Effect: From Rural Kentucky to 7 Years at MIT 0:09:50 - Confident Learning, Two Systems of Intelligence, Classical ML Has to Prevail 0:20:37 - Origin of CleanLab and Handshake acquisition 0:28:00 - How does GPT-5 become GPT-6? 0:31:20 - The Fastest growing Data Lab: What makes Handshake different? 0:35:32 - Difference between Good Data and Bad Data 0:38:17 - New kind of Data, IA and AI 0:42:04 - Scaling Coding Benchmarks and Efficiency in Long Horizon Tasks 0:49:12 - On Pre-Training, Misconception around Human Data 0:57:13 - Open Question: Taste and Personality, Quick Fire 01:05:15 - Advice to 20yo : Skill and Obsession

himanshu

22,221 Aufrufe • vor 2 Monaten