正在加载视频...

视频加载失败

加载此视频时出现问题。这可能是由于临时网络问题，或视频可能不可用。

Preclinical and observational studies suggest that exercise may improve cancer outcomes. However, definitive level 1 evidence is lacking. The CHALLENGE trial sought to address this knowledge gap. NEJM Editorial Fellow Sarah Gorey, MB (Sarah Gorey), explains in this 60-Second Journal Club video. Read the full trial results:

NEJM

1,033,791 subscribers

12,392 次观看 • 1 年前 •via X (Twitter)

Anya Rossi• Live Now

Private livecam show

2 条评论

Dr. Mahesh Banda 的头像

Dr. Mahesh Banda1 年前

@sarah_gorey First step: Case control studies with family history of cancer and age of presentation with physical fitness as one of the major parameter, might determine the next step for the cohort studies.

Naveen Sankar S 的头像

Naveen Sankar S1 年前

🚴‍♂️ Higher cardiorespiratory fitness may reduce dementia risk, even for those with a genetic predisposition! A study links high fitness to better cognition and delayed dementia onset by over 1.4 years. 🔗 #DementiaPrevention #Fitness #BrainHealth 🧠

相关视频

60-Second Journal Club: NEJM Editorial Fellow Sarah Gorey, MB, summarizes the REDOX trial assessing hospitalization and mortality among patients with chronic severe hypoxemia who received long-term oxygen therapy for either 24 or 15 hours per day. Full trial:

60-Second Journal Club: NEJM Editorial Fellow Sarah Gorey, MB, summarizes the REDOX trial assessing hospitalization and mortality among patients with chronic severe hypoxemia who received long-term oxygen therapy for either 24 or 15 hours per day. Full trial:

NEJM

18,799 次观看 • 1 年前

In this 60-Second Journal Club, NEJM Editorial Fellow Abarna Pearl, MD, MPH, summarizes the BALANCE trial comparing antibiotic treatment for 7 versus 14 days in patients with bloodstream infections. Read the full article and accompanying Research Summary:

In this 60-Second Journal Club, NEJM Editorial Fellow Abarna Pearl, MD, MPH, summarizes the BALANCE trial comparing antibiotic treatment for 7 versus 14 days in patients with bloodstream infections. Read the full article and accompanying Research Summary:

NEJM

10,641 次观看 • 1 年前

NEJM Editorial Fellow Minali Nigam, MD, shares the key results of the ORIENTAL-MeVO trial, which investigated whether endovascular thrombectomy for acute ischemic stroke improves functional outcomes in patients with medium-vessel occlusion and moderate-to-severe deficits. Read the full trial results:

NEJM Editorial Fellow Minali Nigam, MD, shares the key results of the ORIENTAL-MeVO trial, which investigated whether endovascular thrombectomy for acute ischemic stroke improves functional outcomes in patients with medium-vessel occlusion and moderate-to-severe deficits. Read the full trial results:

NEJM

16,994 次观看 • 1 个月前

Pharmacologic treatment options for cancer cachexia are limited. NEJM Editorial Fellow Harleen Marwah, MD, summarizes research on the safety and efficacy of the monoclonal antibody ponsegromab for treating cancer cachexia. Read the full trial results:

Pharmacologic treatment options for cancer cachexia are limited. NEJM Editorial Fellow Harleen Marwah, MD, summarizes research on the safety and efficacy of the monoclonal antibody ponsegromab for treating cancer cachexia. Read the full trial results:

NEJM

16,522 次观看 • 1 年前

Observational evidence is conflicting on whether the sex of blood donors affects recipient outcomes. New findings from a randomized trial are summarized in this short video.

Observational evidence is conflicting on whether the sex of blood donors affects recipient outcomes. New findings from a randomized trial are summarized in this short video.

NEJM

42,725 次观看 • 3 年前

Whole-blood transfusion has recently gained favor in the management of severe hemorrhage, but is it really better than standard care with blood components? NEJM Editorial Fellow Katerina Lin, MD, recaps the results of the SWiFT trial. Read the full trial results:

Whole-blood transfusion has recently gained favor in the management of severe hemorrhage, but is it really better than standard care with blood components? NEJM Editorial Fellow Katerina Lin, MD, recaps the results of the SWiFT trial. Read the full trial results:

NEJM

19,223 次观看 • 19 天前

What do you counsel patients with #AFib who are candidates for long-term anticoagulation? NEJM Editorial Fellow Katerina Lin, MD, provides an overview of the recently published CHAMPION-AF trial. Read the full trial results:

What do you counsel patients with #AFib who are candidates for long-term anticoagulation? NEJM Editorial Fellow Katerina Lin, MD, provides an overview of the recently published CHAMPION-AF trial. Read the full trial results:

NEJM

34,919 次观看 • 24 天前

Induction medication for emergency intubation — does the choice matter? NEJM Editorial Fellow Katerina Lin, MD, explains a randomized trial to determine the effects of ketamine vs. etomidate for induction of anesthesia during emergency tracheal intubation. Full RSI trial results:

Induction medication for emergency intubation — does the choice matter? NEJM Editorial Fellow Katerina Lin, MD, explains a randomized trial to determine the effects of ketamine vs. etomidate for induction of anesthesia during emergency tracheal intubation. Full RSI trial results:

NEJM

21,895 次观看 • 4 个月前

This video in our partnership with Dr. Glaucomflecken explains a head-to-head trial comparing rituximab versus ocrelizumab in newly diagnosed relapsing multiple sclerosis. Access the full results of the OVERLORD-MS trial for free: #neurology

This video in our partnership with Dr. Glaucomflecken explains a head-to-head trial comparing rituximab versus ocrelizumab in newly diagnosed relapsing multiple sclerosis. Access the full results of the OVERLORD-MS trial for free: #neurology

NEJM

35,268 次观看 • 1 个月前

Our latest video in our partnership with Dr. Glaucomflecken explains the results of the RESHAPE-HF2 trial investigating whether transcatheter mitral-valve repair improves outcomes in patients with heart failure and functional mitral regurgitation.

Our latest video in our partnership with Dr. Glaucomflecken explains the results of the RESHAPE-HF2 trial investigating whether transcatheter mitral-valve repair improves outcomes in patients with heart failure and functional mitral regurgitation.

NEJM

98,985 次观看 • 1 年前

Our latest video in our partnership with Dr. Glaucomflecken summarizes a new trial investigating the mass administration of ivermectin for reducing malaria transmission. Read the full results of the BOHEMIA trial for free:

Our latest video in our partnership with Dr. Glaucomflecken summarizes a new trial investigating the mass administration of ivermectin for reducing malaria transmission. Read the full results of the BOHEMIA trial for free:

NEJM

19,398 次观看 • 9 个月前

Our latest video in our partnership with Dr. Glaucomflecken summarizes the results of a trial investigating the effectiveness of shunt surgery for idiopathic normal-pressure hydrocephalus. Read the full results for free: #neurology

Our latest video in our partnership with Dr. Glaucomflecken summarizes the results of a trial investigating the effectiveness of shunt surgery for idiopathic normal-pressure hydrocephalus. Read the full results for free: #neurology

NEJM

56,868 次观看 • 7 个月前

Monoclonal gammopathy of undetermined significance (MGUS) is a common, asymptomatic plasma-cell disorder in older adults that can progress to cancer or systemic illness. NEJM Editorial Fellow Katerina Lin, MD, shares some key points from a review published in October. Read the full article:

Monoclonal gammopathy of undetermined significance (MGUS) is a common, asymptomatic plasma-cell disorder in older adults that can progress to cancer or systemic illness. NEJM Editorial Fellow Katerina Lin, MD, shares some key points from a review published in October. Read the full article:

NEJM

16,361 次观看 • 6 个月前

Drs. Greg Katz, MD, Shreya P. Trivedi MD, MHPE & Abby Schubach MD discuss the NordICC trial: Does colonoscopy reduce colorectal cancer incidence? Hear more in the latest episode of Beyond Journal Club, a CORE IM in collaboration with NEJM Group:

Drs. Greg Katz, MD, Shreya P. Trivedi MD, MHPE & Abby Schubach MD discuss the NordICC trial: Does colonoscopy reduce colorectal cancer incidence? Hear more in the latest episode of Beyond Journal Club, a CORE IM in collaboration with NEJM Group:

NEJM

14,595 次观看 • 2 年前

Ondansetron is often prescribed at ED discharge for children seen for gastroenteritis to reduce further symptoms, but evidence to support doing so is limited. A new trial investigates whether postdischarge ondansetron is beneficial. Full trial results:

Ondansetron is often prescribed at ED discharge for children seen for gastroenteritis to reduce further symptoms, but evidence to support doing so is limited. A new trial investigates whether postdischarge ondansetron is beneficial. Full trial results:

NEJM

14,357 次观看 • 1 年前

Our latest video in our partnership with Dr. Glaucomflecken summarizes the results of a trial that evaluated whether management of shock without early arterial catheterization is noninferior to the practice of early catheter insertion with regard to death from any cause at day 28. Read the full results for free:

Our latest video in our partnership with Dr. Glaucomflecken summarizes the results of a trial that evaluated whether management of shock without early arterial catheterization is noninferior to the practice of early catheter insertion with regard to death from any cause at day 28. Read the full results for free:

NEJM

47,843 次观看 • 8 个月前

In low-risk patients with MI and early complete revascularization, stopping aspirin after 1 month and continuing P2Y12 monotherapy was noninferior to dual antiplatelet therapy for ischemic outcomes and led to reduced bleeding at 1 year. Read the full TARGET-FIRST trial results in the Original Article “Early Discontinuation of Aspirin after PCI in Low-Risk Acute Myocardial Infarction”:

In low-risk patients with MI and early complete revascularization, stopping aspirin after 1 month and continuing P2Y12 monotherapy was noninferior to dual antiplatelet therapy for ischemic outcomes and led to reduced bleeding at 1 year. Read the full TARGET-FIRST trial results in the Original Article “Early Discontinuation of Aspirin after PCI in Low-Risk Acute Myocardial Infarction”:

NEJM

32,419 次观看 • 9 个月前

Could clesrovimab, a human RSV monoclonal antibody, reduce the incidence of RSV infection in preterm and full-term infants? Find out in the latest video in our partnership with Dr. Glaucomflecken. Read the full results of the CLEVER trial for free:

Could clesrovimab, a human RSV monoclonal antibody, reduce the incidence of RSV infection in preterm and full-term infants? Find out in the latest video in our partnership with Dr. Glaucomflecken. Read the full results of the CLEVER trial for free:

NEJM

46,802 次观看 • 9 个月前