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Predicting pelvic recurrence in #BladderCancer: A five-factor risk score. Vidit Sharma Mayo Clinic Urology joins Ashish M. Kamat, MD, MBBS MD Anderson News discussing a new pelvic recurrence risk score developed at Mayo Clinic and validated in #Milan. 🔹 Derived from 1,200 cases 🔹 5-year recurrence: 2%–52% (C-index 0.73–0.75)... show more
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![yesterday someone leaked a full quant trading system on GitHub before they deleted it i forked everything 5,000 lines of code. 7 modules. 25 mathematical factors funds use this system to manage millions i studied it for a week. then pointed it at crypto markets on polymarket here's the full breakdown you can feed this to your claude and build the same thing for just $200 ARCHITECTURE: Python thinks, analyzes, calculates C++ executes orders in 5-10ms data → factors → AI → strategy → risk → execution DATA. 4 streams simultaneously: - Binance WebSocket: prices every second, orderbook at 20 levels - AlphaVantage: news with sentiment score from -1 to +1 -X: mention volume, engagement, influencer activity - On-chain: BTC flows to/from exchanges cache in Redis ( target price) = N(d1) d1 = [ln(current/target) + (σ²/2)T] / (σ√T) then 4 adjustments on top: - momentum: +/-5% - AI sentiment: +/-7% - order flow: +/-2% - historical patterns: +/-8% compare final probability against polymarket price if edge > 10%: enter RISK - Quarter Kelly for position sizing - max 5% bankroll per trade - drawdown 15% = bot stops - VaR < 3% per day - correlation between positions < 0.7 - never take more than 1% of market liquidity key insight is don't hold to expiry. trade the movement, not the outcome cost: → Binance API: free → OpenAI: $50-100/month → AWS EC2: $120/month → monitoring: free - total: $200-300/month - code is open source. formulas above. you already have claude the only thing between you and a working system is one free evening](https://image.24vids.com/tw-2028582457000247657/amplify_video_thumb/2028582094247481344/img/KlC6FLZJsc2yRvTI.jpg)
![Oncologist Dr. William Makis: "The turbo cancers after the COVID vaccines do respond to the antiparasitics, and they respond very well... [And] why do these antiparasitics work?" Todd Callender: "Cancer's a parasite?" Makis: "That's one possibility." This clip of Dr. Makis (William Makis), a radiologist, oncologist, and cancer researcher, is taken from an interview with attorney Todd Callender posted to the VaxxCHOICE (VaxxCHOICE) Rumble channel on November 21, 2025. ---------------Partial transcription of clip---------------- Dr. Makis: "The turbo cancers after the COVID vaccines do respond to the antiparasitics and they respond very well. This is, you know, whether it's ivermectin, fenbendazole or mebendazole, these patients are responding. "Now this is very important because patients who've developed cancer after taking Covid vaccines, they don't respond usually to conventional treatments. That's one of the hallmarks of turbo cancer is they present at a very late stage. These are extremely rapidly growing tumors. They're coming in at stage four. And it's whether it's young women with breast cancer, women in their 20s, something we've never seen before, young women with, men and women with colon cancer in their 20s and 30s. "Again, we've never seen—" Callender: "Two- year-olds, I've heard of two- year-olds with colon cancer—" Dr. Makis: "—we've never seen this before. That's the incredible part. And they're not responding to conventional treatments. So, they're not responding to chemo, they're not responding to radiation therapy, immunotherapy, or if they do response, they have a very, very short response time or remission time. And then the cancer comes roaring back. "And in a lot of these tragic cases, the patient dies within six months. This is another one of the features of turbo cancer is the prognosis is extremely poor if you go the conventional route. So you need something else. Now when you're using antiparasitics, for cancer, the dose is higher than the dose you would use to treat parasites or to treat Covid. So I give just a rule of thumb for ivermectin, for example, it's about five times the dose that you would need for cancer, about 5 to 10 times the dose than if you were just treating parasites or viruses. "And to go into the— why does it work? Why do these antiparasitics work?" Callender: "Cancer's a parasite?" Dr. Makis: "Well, that's one possibility. But there's more to it than that because, out of the 400 papers that have been published, a lot of those researchers look at the mechanisms. They are trying to identify the mechanisms of how ivermectin is treating these cancers. "And you've got, for example, there was one study published a few years ago, Mexican researchers, again, you're not going to see this done in the United States, Mexico. Mexican researchers took 28 different cancer cell lines, applied ivermectin to them, and all of them responded. Now to various degrees, you had breast cancer and ovarian cancer actually responding the most to ivermectin. You had the most cancer cell killing when they were exposed to ivermectin. "But when they look at the mechanisms, they've identified a number of interesting things. For example, ivermectin shuts down and kills cancer stem cells. Now, this is important because cancer stem cells are the reason chemotherapy doesn't work. When you have stage four pancreatic cancer, stage four ovarian cancer, and you go to your oncologist, they will tell you, we will give you chemo, but we can't cure you. It's palliative chemo. It'll buy you an extra six months, an extra 12 months of life. "The reason why they say that is why the chemo is palliative, not curative. It's is because chemo cannot kill cancer stem cells, which are not rapidly dividing. Chemo will kill everything that's rapidly dividing, but cancer stem cells are not rapidly dividing. And so the chemo will kill the rapidly dividing tumor cells, and it'll leave the cancer stem cells alone, while the cancer stem cells will start rapidly dividing a year later, two years later, they're going to spread to other parts of the body. Suddenly you've got recurrence, you've got metastases. Ivermectin will shut down and kill cancer stem cells. "So imagine you, added to your chemo regimen, and now you've essentially turned what's palliative chemo or a palliative situation to potentially a curative situation. And I really do believe I've come to the point, having helped over 7,000 cancer patients in the last year, I've come to the point where I could confidently say that stage 4 pancreatic cancer is curable, stage 4 ovarian cancer is curable, stage 4 colon cancer, lung cancer. These cancers are curable. I think if you add repurposed drugs, you add antiparasitics, you can turn these into curable situations. "Now, of course, we have to prove that. We have to do the research, do the publications. But in the meantime, I say stage 4 cancer patients don't have 10 years to wait for mainstream oncology or mainstream medicine to catch up with what we're seeing already clinically, in practice."](https://image.24vids.com/tw-1993127013713166353/amplify_video_thumb/1993124339852754944/img/m5izGyXtNBTWkWd4.jpg)
![My fellow Kenyans, Many of you have seen my recent posts about the deadly cancer that is corruption in our country. In my last post, I tried to paint a picture of the disconnect between our potential as a country and the economic circumstances we find ourselves in today, and the connection between corruption and the incalculable pain and suffering and cruelty that is meted out every single day to the most vulnerable among us by thieves operating out of public office. And after covering the goings-on in Mandera County, I told you that in my honest opinion, our governments exist to cater for the filthy-rich lifestyles of the vilest and most corrupt among us, at the expense of everyone else. I received tremendous support from all of you, for speaking on behalf of so many struggling Kenyans who don’t have a voice, or the audience necessary to spark the much-needed discussion about where we are heading as a country. But even with all that support, I have received messages asking me to be careful. One compatriot told me: “prepare to be relentlessly pursued, threatened, enticed, guilt-tripped, and gas-lit”. This is from a someone who knows how our government operates, and how it uses violence and its monopoly on power to silence those who question why politicians are stealing so much. I am not naive about the dangers of speaking up and calling out thieves who control state machinery, and who possess the ability to shut me up in a few seconds. But I will tell you why we CAN NOT and MUST NOT keep quiet. In November of 2023, I stumbled upon the story of a young man from Turkana, Calvin Esekon Esewit , who, despite scoring an A-, and getting an acceptance into medical school, spent two years not knowing whether his dreams of becoming a doctor would ever come true. I was moved by that story in a way that I can never adequately explain. I could not understand how it is possible that, in our country, a young man who appears to be every parent’s dream child can spend two years in limbo while we as a country possess the ability to invest in our best and brightest. And so, I spent weeks trying to chase down Calvin to see how I could help him attend college. After a lot of searching, I finally found Calvin, and by this time he had managed to get some help and is now in college. While this story has a great ending, it did not to be this way. And we know that the number of cases that end like this, with some success, are a small fraction of those ones which end tragically, with broken dreams. This is what happens when corruption consumes anything and everything in a country. It destroys lives. See attached video to learn about Calvin's story. I tell you all this story because it provides context to today's topic. For one story like this one that you see on the news, there are millions that never make the news. But they are real situations, nonetheless. There are millions of your compatriots who are devastated by this killer cancer of corruption that is perpetuated by people that you and I have put into public office ostensibly to improve our lives. They go into these offices and abuse the trust you bestowed upon them and deny you and everyone else a decent opportunity in life. You see, Calvin and millions of other victims of this shameless level of corruption and plunder have no voice, and no real ability to look the thieves that are destroying lives and generations of Kenyans in eye and tell them to stop this unbearable pain and the cruelty. This is the reason I embarked on this journey to attempt to expose this shameful situation. Watch the attached video of Calvin’s situation, and I am sure that you will agree that the millions of Calvins in our country need a voice, NO MATTER THE RISK. The thieves that are destroying the futures of millions of children just so they can have beachside homes in Miami, Dubai and other places count on the idea that most people will fear for their lives, and therefore not speak up. They count on the growing apathy in the Kenyan psyche. But we cannot give in to that. We cannot cower to thieves. We must look them straight in the eye and tell them that they MUST STOP. If we don't, our children and their children are guaranteed the same level of cruelty. And so with that, today I want to talk about the utterly insane crime scene that is Turkana County. I don’t know any other way to describe it, other than, it is a “shit-show”. Just follow along, and let me know if you disagree. As I did in my previous commentary, I will ask you to indulge me a little bit, and allow me to use a couple of pictures, because pictures speak louder than a thousand words. The first picture shows the state-of-the art County Government offices, that the County Government of Turkana decided to invest an ungodly amount of money on. Close to a billion shillings. The second picture is a classroom in session. In Turkana County. These two realities are occurring in parallel in the same county, at the same time. Ladies and gentlemen, let me just tell you that I do not go out of my way to find bad news. I want stories that would help re-affirm our belief in the fundamental decency of human beings. When I find good news as I review these Counties’ decisions and how they behave with our resources, I will be the first one to report it to you. But I don’t have any good news today. I have bad news. If you read my commentary yesterday and were offended by what you saw, I am afraid you might not make it to the end of this article, because what you will hear will be quite shocking. The cancer of corruption, particularly at the County Government level, is worse than your wildest imagination. And so, as I like to do, I like to start off by putting some numbers on the table for us to use as reference points. Bear in my that all the information I put in this article is publicly available. Nothing came to me through a whistle blower. The first number is KSH 100 Billion. With a B. In the last decade or so, you and I, through the National Government, has sent over KSH 100 billion to Turkana County. To support recurrent expenditure, and development. For example, in the 2022-2023 fiscal year, we sent KSH 12.6 billion. In the 2021-2022 fiscal year, we sent KSH 11.4 billion. And on and on and on. The second number is 1 million. This is the population of Turkana County. The third number is KSH 18.4 billion. This was Turkana County’s budget for the 2022-2023 fiscal year. The fourth number is KSH 190 million. This was the amount of money that Turkana County was able to generate on its own accord within the county, from all its investments and other activities in the period in question. This number is an important proxy, in my view, for the value of the county’s economic prospects for the foreseeable future, and to people that are not driven by greed and corruption, would be an important consideration when they are thinking about how and where to deploy your money as taxpayers. If you are doing the math, Turkana County, for the 2022-2023 fiscal year, was only able to raise 1% of the funds needed to keep the lights on. 99% came from you and I, and a tiny amount from grants. The next number is KSH 129, 040. This is the average ANNUAL [emphasis added] income of a resident of Turkana County ( Keep that number in mind when we are discussing the massive theft of public funds by Turkana County leaders. The next number is 80%. 80% of the residents of Turkana County live below the poverty line. They have a really difficult time putting food on the table. ( The next number is KSH 12 Million. This is the basic salary of the Governor of Turkana County before other benefits that, as I explained yesterday, can often double the salary. Remember the “housing allowance”, the “hardship allowance”, the “commuter allowance”, the “risk allowance”, the “extraneous allowance”, etc.? Remember that? I still cannot figure out, for the life of me, what “extraneous” means in the context of County business, but we don’t time to dwell on this. The next number is 93. The Governor of Turkana County makes 93 times the average Turkana County resident’s annual income. 93 times! The next number is 82%. This was the percentage of people that were illiterate in Turkana County in 2013 ( Could not read or write. A point to note about the above literacy figure. Ten years later, and despite over KSH 100 billion is spent in Turkana County, including many billions for education, that literacy rate HAS NOT CHANGED ONE BIT. Only 20% of the population can read or write today. ( KSH 829 million. This is how much it cost to build the County Government offices. Yes, the ones shown in the first picture. KSH 120 million. The County Government decided that it was prudent to pay a contractor KSH 120 million to construct the Governor’s personal residence. Get this, even after this payment, no construction took place. The money was stolen. All of it. KSH 90 Million. This is the amount that the County Government paid to another contractor, to build the Governor a mansion, having previously lost KSH 120 million. So, the tally for the Governor’s residence now stands at KSH 210 million. Never mind that the limit allowed by law is KSH 45 million. KSH 5 billion. In the last days of his term in office, an outgoing Governor of Turkana, Koli Nanok, EGH. , sought to inflate pending bills by adding KSH 5 billion so that it can be paid to his criminal cartel. KSH 5 billion. We have our key numbers, ladies and gentlemen, so let us discuss. So, we have a county that is dead last in literacy, and in the top 2 of the poorest counties in the republic. Only 20% of the population can read. The Governor earns 92 times the average citizen. The Governor lives in a house that cost over KSH 200 million. When he leaves his house in the morning, he goes to his office that cost KSH 829 million. And this is all happening when 80% of the County residents struggle to put food on the table. Those are the facts, and they are not in dispute. During the same time, the County Government geniuses decide to build the Speaker of the County Assembly a house. And a home office, and a garage. The house was initially estimated to cost KSH 75 million. But due to circumstances that not a soul in the government could explain to auditors, the contract expired before the house was completed, and the County Government found a new contractor to complete the job for an additional KSH 29 million. But this palace in the jungle worth apparently worth over KSH 100 million in Turkana County was not enough. The County proceeded to build the Speaker a guest house for another KSH 19 million, and a few other amenities, and so the whole cost went to KSH 276 million! The legal limit for a Speaker’s house is KSH 35 million, and they spent close to KSH 130 million just for one residence. By this time, I am sure you are getting tired of these obscene numbers. You and I work, and pay taxes. Nobody pays you 92 times the income your average neighbor is making. And for sure nobody will drop KSH 100 million to build you a house. These are the perks of working in government in a poor country. Go figure. And so, as a country, we need to answer for ourselves the question I posed yesterday, which is, what is the point of government? What is its role in our lives. If this level of criminality and pillaging can occur in our country in the midst of so much poverty, questioning the need for government is a totally valid question. I said in my last post that, when the average citizen looks at the thug on the street and the government, and is unable to discern any meaningful difference between them, that society from that point on is on its journey to becoming a failed state. A journey to anarchy. Over the last two months or so, Kenyans have been shouting at the top of their lungs, begging for their government to listen. To hear them out. Kenyans have asked that their government stop this unbelievable level of plunder. Dozens of Kenyans have died, thousands injured, and many more are missing today. To this day, the people that govern us continue to use the power of the gun to subdue Kenyans, until they can take everything in their sight. And so, as a society, we all have to ask whether today there is any difference between the thug on the street and our governments. Every Kenyan will have to answer this question for themselves. And before answering this question, everyone needs to remember the many Calvins in our society. Smart, upright children whose only crime is to be born in an unforgiving, lawless, and corrupt purgatory that is Kenya today. For myself, I have concluded that there is no difference between the thug on the street and our governments, county and national alike. If you can see any meaningful difference, let me know. I am willing to listen. So despite over KSH 100 billion in money sent to Turkana County, there is almost no measurable improvement in people’s life today. None. And it makes sense, when you look at how that money is spent. I want you to forget for a second the obscene obsession by the County Government with spending ungodly amounts of money on themselves. The houses, etc. If you step back and look at how the government is actually spending the hard-earned money on other things, you will be depressed. I am telling you that I wept three times in the middle of the night trying to make sense of this crazy situation in Turkana County. Three times. I have never imagined that human beings can be so greedy and cold-blooded. Think about this: In the couple of years I reviewed, the County spent around KSH 400 million annually in “tourism” initiatives, including marketing, and apparently upgrading certain facilities. KSH 400 million for tourism. In Turkana County. In 1 year. KSH 400 million per year in marketing and other money pits. The government’s own website says that the county gets around 3000 visitors per month. Around 36,000 per year. That’s them saying that, on their website. Are you curious to know the return on that KSH 400 million investment? I have an answer for you. Remember that I told you that the County has never raised more than KSH 200 million in a year within the county, despite its KSH 18.4 billion budget? Let me walk you through the breakdown of the absolutely embarrassing shit-show that is the County Government’s “own source revenue” operations. In 2022-2023, the County Government collected KSH 190 million locally against their KSH 18.4 billion budget. 1% of the budget. Remember, there is absolutely no requirement on the County to cut costs, or achieve certain local revenue targets today. So they raised KSH 45 million in single business permits, KSH 72 million in CESS, KSH 8 million in market fee, KSH 9 million in “slaughter fees”. And then finally, there is the return on the tourism investment that you were looking for. A whopping KSH 209, 000 in “park fees”. KSH 209,000 in fees, after investing KSH 400 million. And so, take this as an example and extrapolate it across the entire budget, and you can see how one can spend KSH 100 billion and get NOTHING in return. You don’t need to be a genius to see the absurdity of this situation. Let me explain using an example that should illustrate the utter dimwittedness of this situation. Remember the KSH 100 billion sent to Turkana by you and me? Part of this amount is supposed to be for “service delivery”, or “recurrent expenditure”. Usually about 70% of the budget. The balance, 30%, is designed to go to development projects. With that in mind, from KSH 100 billion, the County apparently has made KSH 30 billion worth of investments, right? 30% of the KSH 100 billion. Now, if you employed someone to run a business for you, and they asked you to invest KSH 30 billion, which is no small fortune, at some point you would have to start seeing returns, right? That’s common sense, isn’t it? So, when we look at the revenues streams that make up this paltry sum of KSH 190 million, and see things like “slaughter fees’ and “market fees”, what does it tell you? It tells me there is no real “development” happening in that county. Trust me, if you had real development totaling KSH 30 billion, you would have corporate taxes in the hundreds of millions or billions, a booming real estate market, rising wages and standards of living, etc., low unemployment, etc. You would not have 80% of the people living hand-to mouth, and a County Government that can not afford to support itself for 5 days out of the year that has 365 days! We do not have enough time, trust me, to deal with the shit-show that is Turkana County. Dealing with that mess would require a forensic team. I will just highlight a few of other “in your-face” type of theft of public funds, and then conclude my submission. A government that has a budget of KSH 18.4 billion annually, and which has never raised more than 1% of its budget had the wisdom to do the following with your money: · Spend KSH 222 million on a project building something that NOBODY uses. You got that right. They spent KSH 222 million on a facility that NOBODY uses. KSH 222 million gone to waste, in a county that is dead last in pretty much all measures of human progress. · Remember the County Government offices that cost KSH 829 million? The County spent KSH 82 million on “air-conditioning” for that building. · Despite the County Spending hundreds of millions for the top three officers of the County, the Governor and his Deputy, in the 2022-2023 year, illegally charged the county (you and I) KSH 2.2 million in housing allowance! · Built two facilities for KSH 16 million, that were completed, but NOBODY uses them. · Entered into a contract for the construction of a plastic use facility for KSH 13 million in 2021. The contractor gets paid KSH 4.9 million, and has never been seen since. · Paid out KSH 62 million in salaries that were not supportable in just one year. They could not point to anybody and say, that is who we paid. · Paid out KSH 27 million in legal fees that nobody could say what they related to. And the County’s Legal Advisor, who, in 2022-2023, had a budget of KSH 123 million, apparently did not know anything about it! · Had an outstanding bill at Kenya Revenue Authority in the amount of KSH 486 million, that did not show up on the County Government’s financial statements. Think about that. KSH 486 million owned to the Kenya Revenue Authority, and that liability is not on the financial statements! This only means that someone took those funds for themselves, which is why the liability would be missing from the county’s books. · Could not account for KSH 367 million in expenditures for 2022-2023. KSH 367 million, in unexplained expenses. · Awarded a contract worth over KSH 200 million to a bidder with no bank statement, against the law. This contract was entered into and approved before the statutory time after the bidding process lapsed. Someone was in a hurry to get paid. KSH 200 million, illegally awarded to a bidder who did not have a 6-month bank statement. · Apparently purchased KSH 1.5 billion in assets in 2022-2023, but kept no records of the said assets. For this reason, NOBODY can verify where these assets are located. KSH 1.5 billion. Let me just say this. In my last article, the most common critique was that it was too long. Too many words. I did not intend to make another long article. Trust me when I tell you this, we do not have the time to detail half of the problems in Turkana County. For just 1 year! We do not. Now, you recall my point about how societies descend to madness and anarchy. In our country today, our leaders are accusing those of us who are agitating for honest and transparent governance of being traitors to the country. They call us anarchists, criminals, and merchants of chaos. They are questioning our patriotism. You have all seen the government and its horde of propagandists threatening the Ford Foundation and others because they may have helped civil society keep the lights on, and investigative journalists to have the capacity to continue to do the Lord’s work of investigating criminality in government. As though citizens are so dumb and ignorant, that they cannot see what is going on. The reason why millions of Calvins in this country will never graduate from college and earn a decent living is not because of the Ford Foundation. No. It is because of the thieves we have in office today, like the ones in Turkana County. In this post, I copy our leaders, the President and his deputy. I copy them because I want them to help Kenyans understand the following conundrum, about crime and criminals. There is nothing so special or peculiar about criminals or where they pop up. There are criminals in the US, Canada, France, and other places. Just like we have criminals in Kenya. The difference between banana republics and failed states, and civilized societies, is WHAT we do to and about criminals. In civilized societies, criminals are prosecuted and punished heavily. They are shunned. In some places, those charged with serious crimes such as corruption are executed. These are societies that are committed to sending the message that corruption, which robs citizens of their rights, is not acceptable. And they demonstrate this commitment by heavily punishing those who steal from the most vulnerable in society. In Kenya, we see the opposite. Criminals are exalted. They are promoted and embraced in government. It was just last week that the president unveiled his nominees for his Cabinet. Among them, are the likes of Hassan Ali Joho, EGH. , @GovWOparanya , and Davis Chirchir, ALL people who have been accused or charged with massive corruption against Kenyans. And am sure you remember that I mentioned Koli Nanok, EGH. , the man who tried to steal KSH 5 billion in his last days in office. Would you believe it if I told you that he works in government, at State House? He plunded billions of your money, got no measurable improvement in the lives of his subjects, and now has a government job in State House. Let that sink in. And so, the question is, how is it that in a country of 55 million people, with thousands of highly qualified people who have never ever stolen from Kenyans, he ends up with the criminals and thieves in the government, despite the fact that their crimes are in the public domain? How is this possible? Is it possible that these thieves possess a certain unique ability to run government, save Kenyans billions, and solve problems in a way that the president performs a cost-benefit analysis, and the benefits outweigh the costs of their theft? If not, what message does it send to Kenyans, when their own president puts into office known thieves? I think that is a fair question, don’t you? Dr. Ekuru Aukot Rigathi Gachagua William Samoei Ruto, PhD Okiya Omtatah Okoiti Citizen TV Kenya Nation Breaking News TI-Kenya CNN County Government of Turkana](https://image.24vids.com/tw-1818840969066037558/ext_tw_video_thumb/1818834432502951936/pu/img/ab9du2ECDO-A_5N7.jpg)