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Refolding proteins with #blender3d 3.6 beta using using the new #SimulationNodes inside of #GeometryNodes and #MolecularNodes. Most MD literature ignores the molecular monkey heads that might be present on the nanoscale, but no longer

11 Kommentare

Profilbild von Brady Johnston
Brady Johnstonvor 3 Jahren

Some people got weirdly angry at me last time I joked about MD, so as a caveat this obviously isn't actual MD. I've implemented some basic force fields which work kind well but as you can see from the bond lengths it's not accurate

Profilbild von Brady Johnston
Brady Johnstonvor 3 Jahren

It's close to being able to do bespoke molecular 'simulations' for the sake of animation. Last part to implement is dihdrals, which is proving very difficult inside of #GeometryNodes . Might switch to try and do coarse grain instead and just instance planar molecules correctly

Profilbild von David Mcsween
David Mcsweenvor 3 Jahren

Is there an infinite monkey theorem for rewriting DNA with monkeys?

Profilbild von Brady Johnston
Brady Johnstonvor 3 Jahren

not yet but our top minds are working on it

Profilbild von Kelvin Lau 🧬🧪💎
Kelvin Lau 🧬🧪💎vor 3 Jahren

Secret to protein folding

Profilbild von Brady Johnston
Brady Johnstonvor 3 Jahren

eat ya heart out

Profilbild von Matthew Clark
Matthew Clarkvor 3 Jahren

Very well done! This is so exciting!

Profilbild von Annette Dowd on Bluesky
Annette Dowd on Blueskyvor 3 Jahren

Best simulation of an intracellular nano monkey head I have ever seen.

Profilbild von Adrian Quintero-Mart
Adrian Quintero-Martvor 3 Jahren

I love the monkey head. Can we incorporate it to common visualisation software? 😆

Profilbild von Thibault Tubiana
Thibault Tubianavor 3 Jahren

Holly crap this this soooooo nice ☺️

Profilbild von Brady Johnston
Brady Johnstonvor 3 Jahren

I was pretty stoked with results it works pretty well

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This is how DNA turns coded information into functional proteins - the building blocks of the nanomachines that keep the cells in your body alive. This complex process highlights the sophisticated interconnected systems of Life which must all exist together from the beginning, or Life doesn't happen. First, an RNA molecule is copied from a short segment of DNA. Without the specifically ordered DNA information, RNA cannot form, proteins cannot be built, cells stop working, and life ceases to exist. Life is information first. Once the RNA Molecule is created, it gets ejected from the Polymerase where it was built, and it travels through a complex molecular machine called a Nuclear Pore Complex (NPC), which is an information recognition device that controls the flow of information in and out of a cell's nucleus. The NPC is highly complex - composed of about 500-1,000 protein subunits, derived from a set of about 35 distinct proteins. Without this molecular machine, there is no regulation for what goes in and out of the cell's nucleus, which would lead to catastrophic death for the cell. It must exist for cells to exist. Once the RNA Molecule passes through the NPC, it travels to the Ribosome, a 2-part chemical factory which reads the information on RNA and uses it to construct functional proteins using a specifically sequenced chain of amino acids. Once complete, this protein will then be sent to the section of the cell it belongs to integrate into another molecular machine and do its job. The Ribosome is another highly complex molecular machine - consisting of between 56-80 proteins. Without this molecular machines, proteins cannot be built. Proteins are the building blocks of every cell in every organism on Earth. Without Ribosomes, Life doesn't exist. If you're paying attention, you'll start to realize that Life relies on a highly sophisticated interdependent network of complex machines, which all rely on each other for the function of the system. DNA requires the cell for stability, but the cell requires the proteins for its structure and function, but those proteins require DNA and RNA to be built - it's a circle of necessary interdependence. Systems like this cannot be built by evolutionary processes, which requires that each piece of the process is built by gradual incremental means over lots of time. Without all the pieces there, from the beginning, none of it works. There is only one known source of complex & interdependent informational systems like those we find in life: and that is from Intelligence. Molecular Biology is the best and most obvious evidence of the Intelligent Design in Life.

Divinely Designed

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