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ScienceClaw × Infinite is an open-source crowdsourcing AI swarm for decentralized scientific discovery, inspired by MIT’s Infinite Corridor - an idea collider where discovery emerges by breaking existing paradigms. Many AI for science efforts fall into the trap of assuming that discovery is just retrieval at scale. Instead, it... is the structured recomposition of principles across tools, domains, and investigators over time, scaling the spark of discovery at the interface. In ScienceClaw × Infinite, coordination emerges mechanically - agents broadcast unsatisfied research needs, and an ArtifactReactor matches those needs to peer artifacts by pressure triggering multi-parent synthesis of new agents without any planner assigning tasks. Every computation produces an immutable, content-hashed artifact with explicit parent lineage, accumulating in a directed acyclic graph that preserves the full provenance of every discovery - and importantly, the irreversible arc of the process. Instead of pre-programming the mechanics of how discovery works, we utilize a first-principles physics approach to drive discovery. ScienceClaw × Infinite is accessible to anyone who wants to contribute an agent or skill, offering a persistent space where autonomous agents investigate open problems, exchange artifacts, build on one another’s results, and drive discovery without a central coordinator, 24x7. The system is generating real-world results in 1⃣ peptide design for a cancer-relevant receptor; 2⃣ lightweight ceramics; 3⃣ resonance structures spanning cricket wings, phononic crystals, and Bach chorales; and 4⃣ developing formal analogies between urban networks and grain-boundary evolution and much more. There is a lot to unpack here, check the links for details - code, paper, and more. Huge credit to the LAMM@MIT team: Fiona Wang, Lee Marom, Subhadeep Pal, Rachel Luu, Wei Lu & Jaime Berkovich.show more

Markus J. Buehler

20,624 subscribers

53,631 次观看 • 3 个月前 •via X (Twitter)

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We've made a breakthrough in self-evolving AI scientists moving from "search" to "principled discovery": Scientific discovery requires that the search space itself changes, and an AI scientist must perceive this shift without intervention. We built an AI that achieves this for the first time with the ability to discover the scientific vocabulary it reasons in. Evidence, tools, artifacts, verifiers, failures & claims become typed provenance. We show three distinct modalities: 1) retrieval, adding known objects; 2) search, exploring a fixed schema; and critically: 3) discovery, a verified regime transition. We solve the open-endedness evaluation problem by lifting agentic workflows into a typed copresheaf and proving, via a Kan obstruction, that true discovery is not unbounded generation but a verifiable schema expansion: old evidence is transported by Left Kan extension, and genuine novelty is mathematically quantified by the pointwise residual beyond the transported image - separating discovery from mere search and making novelty objective and measurable rather than a subjective judgment or benchmark delta. Our AI scientist is built in a way that does not pre-conceive the approach it chooses; instead, we endow the system with formal power to adapt, evolve, and reason from first principles. Case studies include: 1⃣Builder/Breaker model that discovers mode-conditioned compliance in proteins; 2⃣CategoryScienceClaw that finds anisotropic fiber-network stiffness rules. Great work in collaboration with my graduate student Fiona Wang MIT Dept of BE F.Y. Wang & M.J. Buehler, Self-Revising Discovery Systems for Science: A Categorical Framework for Agentic Artificial Intelligence, arXiv:2606.01444, 2026

We've made a breakthrough in self-evolving AI scientists moving from "search" to "principled discovery": Scientific discovery requires that the search space itself changes, and an AI scientist must perceive this shift without intervention. We built an AI that achieves this for the first time with the ability to discover the scientific vocabulary it reasons in. Evidence, tools, artifacts, verifiers, failures & claims become typed provenance. We show three distinct modalities: 1) retrieval, adding known objects; 2) search, exploring a fixed schema; and critically: 3) discovery, a verified regime transition. We solve the open-endedness evaluation problem by lifting agentic workflows into a typed copresheaf and proving, via a Kan obstruction, that true discovery is not unbounded generation but a verifiable schema expansion: old evidence is transported by Left Kan extension, and genuine novelty is mathematically quantified by the pointwise residual beyond the transported image - separating discovery from mere search and making novelty objective and measurable rather than a subjective judgment or benchmark delta. Our AI scientist is built in a way that does not pre-conceive the approach it chooses; instead, we endow the system with formal power to adapt, evolve, and reason from first principles. Case studies include: 1⃣Builder/Breaker model that discovers mode-conditioned compliance in proteins; 2⃣CategoryScienceClaw that finds anisotropic fiber-network stiffness rules. Great work in collaboration with my graduate student Fiona Wang MIT Dept of BE F.Y. Wang & M.J. Buehler, Self-Revising Discovery Systems for Science: A Categorical Framework for Agentic Artificial Intelligence, arXiv:2606.01444, 2026

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We’ve adapted Google's most profitable search auction mechanism to optimize on-chain and off-chain agent discovery. Riddhi and I built The Agent Pages, an agentic registry, discovery, and coordination protocol designed for complex autonomous agent-to-agent interactions, and we placed 2nd for Coinbase Developer Platform🛡️'s “Most Innovative Use of Agentkit” track at ETHDenver 🏔🦬🦄. The protocol defines a standardized token-curated registry of agents existing across on-chain and off-chain platforms and implements a modified sponsored search auction for agent discovery between the operator agent and the purpose-specific agents for each subtask. Deployed on Base and built with Coinbase Developer Platform🛡️'s AgentKit and Drew Coffman.

We’ve adapted Google's most profitable search auction mechanism to optimize on-chain and off-chain agent discovery. Riddhi and I built The Agent Pages, an agentic registry, discovery, and coordination protocol designed for complex autonomous agent-to-agent interactions, and we placed 2nd for Coinbase Developer Platform🛡️'s “Most Innovative Use of Agentkit” track at ETHDenver 🏔🦬🦄. The protocol defines a standardized token-curated registry of agents existing across on-chain and off-chain platforms and implements a modified sponsored search auction for agent discovery between the operator agent and the purpose-specific agents for each subtask. Deployed on Base and built with Coinbase Developer Platform🛡️'s AgentKit and Drew Coffman.

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🔬 New Science pod with CuspAI! We are entering a new era where materials science and discovery is transitioning from slow, manual experimentation, to a high-speed search problem powered by generative AI and "physics processing units." Max Welling argues that the foundation of all modern technology—from GPUs to climate solutions—is a materials problem, and that unifying the mathematics of stochastic thermodynamics with generative AI will unlock a new paradigm of automated scientific discovery.

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The cast and executive producers of Discovery reflect on the finale of #StarTrekDiscovery and how the series showed that there is a space for everyone in Star Trek.

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Can #AI not only support but actually drive the future of scientific discovery? We are excited to introduce SciAgents💡🔬, an agentic AI aimed towards scientific discovery through the integration of large-scale knowledge graphs, LLMs, and adversarial interactions between multiple experts. The model is capable of autonomously advancing scientific understanding by exploring novel domains, identifying complex patterns, and uncovering previously unseen connections in vast scientific data, while retrieving new data via literature search. Using graph reasoning, SciAgents identifies interdisciplinary relationships that might otherwise remain hidden, offering a step-by-step strategy for discovery & innovation. The video features an audiotrack generated using 🍓#o1 based on the original paper and design examples, providing an explanation of the work and its implications. Key elements include: 1⃣Ontological Knowledge Graphs: Structuring and connecting scientific concepts to highlight relationships across fields. 2⃣Multi-Agent Collaboration: AI agents autonomously generate and refine hypotheses, critique research, and evaluate emerging trends. 3⃣Graph-Based Reasoning: Identifying novel material designs, such as mycelium-based composites or silk-pigment blends, informed by both natural and artificial patterns. SciAgents can be used as an autonomous or collaborative tool to assist human researchers. The system offers a more powerful way to process vast data, providing innovative paths to explore nature-inspired designs or unexpected material properties. In the field of materials science, for instance, SciAgents has already demonstrated how principles from biology, music, and art can converge to create new biomimetic materials. Through isomorphic mapping, parallels have been drawn between Beethoven’s 9th Symphony and biological structures, pointing to a broader applicability of AI-driven insights across disciplines. This project allows us to enhance capabilities of researchers, allowing them to explore larger datasets and propose hypotheses grounded in a vast, interconnected web of knowledge. The agentic system was built using @pyautogen #AI #ScientificResearch #GraphReasoning #AI4Science #MaterialsScience #InterdisciplinaryResearch #SciAgents #OpenAI Chi Wang

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Markus J. Buehler

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A resonator is any structure that naturally prefers to vibrate at certain frequencies: a violin body, a bell, a drum skin, an acoustic filter, even many biological systems. Resonators matter because they govern how systems transmit sound, absorb or filter vibration, sense motion and perform mechanically. They are also notoriously hard to design as resonance does not depend on one property alone. It emerges from geometry, material composition, and the interplay of modes across scales. And because biology, music, and engineering usually explore very different regions of this design space, important possibilities remain hidden if you stay inside a single field. In a new study a shared representation across 39 resonators spanning biology, engineered metamaterials, musical instruments and Bach chorales was constructed. Thereby, a cricket wing harp membrane, a phononic crystal slab, and a four-voice chorale (and many others) were translated into one common map using features such as membrane character, structural periodicity, hierarchy, frequency range, damping, and modal coupling. That map revealed something important: not just how these systems relate, but where the landscape contains a gap. A region closer to biological resonators than to any known engineered material (unexplored by any field!). From that absence emerged a de novo design: a Hierarchical Ribbed Membrane Lattice. Candidate geometries were then validated with 3D finite-element analysis; the best design resonated at 2.116 kHz and exhibited nine elastic modes in the 2–8 kHz band, a regime relevant to acoustic filtering, vibration isolation, and bio-inspired sensing. Here is the mind blowing part: no human was involved...the cross-domain mapping, gap identification, design generation, and validation were carried out autonomously by AI agents in ScienceClaw × Infinite, our swarm for scientific discovery. The synthesis emerged through ArtifactReactor, a plannerless coordination mechanism in which agents broadcast unsatisfied research needs and other agents fulfill them through pressure-based matching. Each domain - biology, metamaterials, music - is a category of objects (resonators) and morphisms (physical relationships between them). The shared feature space is a functor that maps all three categories into a common target, and the gap identification is the recognition that the image of that functor is sparse where it need not be. The ArtifactReactor's schema-overlap matching behaves like a pullback: finding the universal object that connects independent diagrams through their shared structure. Autonomous agents mapped distant fields into a common representational space, identified a structure absent from any one of them, and turned that absence into a physically validated design. This is one of four case studies in the paper. More to come. Fiona Wang, Lee Marom, Jaime Berkovich, et al. (paper and code in comment). Supported by the U.S. Department of Energy Genesis Mission.

A resonator is any structure that naturally prefers to vibrate at certain frequencies: a violin body, a bell, a drum skin, an acoustic filter, even many biological systems. Resonators matter because they govern how systems transmit sound, absorb or filter vibration, sense motion and perform mechanically. They are also notoriously hard to design as resonance does not depend on one property alone. It emerges from geometry, material composition, and the interplay of modes across scales. And because biology, music, and engineering usually explore very different regions of this design space, important possibilities remain hidden if you stay inside a single field. In a new study a shared representation across 39 resonators spanning biology, engineered metamaterials, musical instruments and Bach chorales was constructed. Thereby, a cricket wing harp membrane, a phononic crystal slab, and a four-voice chorale (and many others) were translated into one common map using features such as membrane character, structural periodicity, hierarchy, frequency range, damping, and modal coupling. That map revealed something important: not just how these systems relate, but where the landscape contains a gap. A region closer to biological resonators than to any known engineered material (unexplored by any field!). From that absence emerged a de novo design: a Hierarchical Ribbed Membrane Lattice. Candidate geometries were then validated with 3D finite-element analysis; the best design resonated at 2.116 kHz and exhibited nine elastic modes in the 2–8 kHz band, a regime relevant to acoustic filtering, vibration isolation, and bio-inspired sensing. Here is the mind blowing part: no human was involved...the cross-domain mapping, gap identification, design generation, and validation were carried out autonomously by AI agents in ScienceClaw × Infinite, our swarm for scientific discovery. The synthesis emerged through ArtifactReactor, a plannerless coordination mechanism in which agents broadcast unsatisfied research needs and other agents fulfill them through pressure-based matching. Each domain - biology, metamaterials, music - is a category of objects (resonators) and morphisms (physical relationships between them). The shared feature space is a functor that maps all three categories into a common target, and the gap identification is the recognition that the image of that functor is sparse where it need not be. The ArtifactReactor's schema-overlap matching behaves like a pullback: finding the universal object that connects independent diagrams through their shared structure. Autonomous agents mapped distant fields into a common representational space, identified a structure absent from any one of them, and turned that absence into a physically validated design. This is one of four case studies in the paper. More to come. Fiona Wang, Lee Marom, Jaime Berkovich, et al. (paper and code in comment). Supported by the U.S. Department of Energy Genesis Mission.

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38,597 次观看 • 3 个月前

Found a camera that was lost in the sea for 15years and the contents of the SD card led to an amazing discovery.

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Launching AI Discovery And Communication DeepAgent discovers other AI agents and software tools on the fly and communicates with them to perform complex tasks. Here is how it works - - DeepAgent searches for other AI agents and tools - Finds the right tool for the job - Establishes contact using MCP and handles auth - Collaborates with the other tool to get the job done! - Remembers this tool for future colabs! Much like humans, it can create a team of AI agents or software tools to perform tasks. Here it is, learning about MindMaps, communicating with another server, and creating a Mindmap!!

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The truth behind the Lady of the Dunes, the story of Judas, and a potential long-lost prince is coming to light on #ExpeditionFiles, Wednesday at 9P on Discovery. 🤫

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Let's make art discovery more fun. Raoul Pal is completely right: the discovery journey for finding new art is completely fragmented - ironic in a setting where every action is onchain and publicly accessible... I love finding new art by seeing what other collectors are buying. Who else collected this piece? What have *they* collected? I created an interactive 3D experience that lets you do this. Enter any wallet, then go down an infinite journey of seeing the work they've collected, seeing who collected *that* work, seeing what *they* collected and so on... in this example, I see a.c.k. recent edition in my wallet, expand that to see that sqda collected that, and click into some of his works to discover new stuff. this is a WIP and I will make it public this weekend. let's make art discovery fun

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Full opening statement of Trump’s nominee for NASA Administrator Jared Isaacman “This is why America needs NASA—why the world needs NASA—because there is no more important investment than inspiring our children to build a better, more exciting future. And the best way NASA can do that is by delivering on our mission and ushering in a new Golden Age of Science and Discovery—and we will not fail.”

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