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🦓 Self-supervised multimodal ML is promising the next AI breakthrough - in our new work published in nature, we debut @CEBRAai: for self-supervised hypothesis- and discovery-driven science. 📝 💻 🦓 🧵⬇️

249,881 views • 3 years ago •via X (Twitter)

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Mackenzie Mathis, PhD's profile picture
Mackenzie Mathis, PhD3 years ago

First, this is a story about people 🥳 @stes_io & @jinnnnnlee  are co-first authors and it was absolute pleasure to work with them & see the 🦓 CEBRA magic come to life. A few happy/fun bits in the @Nature research briefing! 🔗

Mackenzie Mathis, PhD's profile picture
Mackenzie Mathis, PhD3 years ago

The work: we focused in on 4 open-access datasets: synthetic, hippocampus, sensorimotor, and vision across species & recording methods to show the general performance and many features of #CEBRA cc @AllenInstitute @sejdevries @PresNCM & more (🙏)

Mackenzie Mathis, PhD's profile picture
Mackenzie Mathis, PhD3 years ago

The strength of CEBRA is the flexibility & performance: no generative model = no restrictions on data, & it can be used unsupervised (Time) or w/labels (Behavior). Here, we demo on hippocampus with CEBRA-Time and then do hypo. testing for a quantitative readout of model fit!

Mackenzie Mathis, PhD's profile picture
Mackenzie Mathis, PhD3 years ago

One big #CEBRA moment for us was seeing the impressive video decoding results: 🐭🧠+🎥->🦓= - high perf. >95% accuracy at frame prediction 🔥 - highly similar latents across Neuropixels & 2-photon data ✅ - differences in performance across the visual system of 🐭

Mackenzie Mathis, PhD's profile picture
Mackenzie Mathis, PhD3 years ago

To be continued... we won't tweet all the science today, so stay tuned for more highlights later 🖤🦓🍾

Mackenzie Mathis, PhD's profile picture
Mackenzie Mathis, PhD3 years ago

✨🦓🖤 Our Research Briefing can now be found at - the problem, our solution, and future directions … 🚨including how CEBRA is not limited to neural data🚨— if you use t-SNE or UMAP, consider using CEBRA for more consistent and higher accuracy results

NeurodataWithoutBorders's profile picture
NeurodataWithoutBorders3 years ago

@Nature @cebraAI Exciting news! 🎉 The @cebraAI paper just got published in @Nature, using secondary analysis of an NWB dataset on the @DANDIArchive 🧠. This marks a new milestone in scientific research and collaboration. Congrats to the team! #OpenScience #research #collaboration #datasharing

Mackenzie Mathis, PhD's profile picture
Mackenzie Mathis, PhD3 years ago

@Nature @cebraAI @DANDIarchive Thanks very much! This is one thing we are proud of in this paper - all data was open source and useable! 🥰 #dandi #figshare #crcns

Fabian Theis's profile picture
Fabian Theis3 years ago

@Nature @cebraAI Congrats Mackenzie and @stes_io - exciting new avenue, let’s try to learn eg cellular or other dynamics.

Ana Marija Jakšić, PhD🦄🧬🪰's profile picture
Ana Marija Jakšić, PhD🦄🧬🪰3 years ago

@sainsbury_tom @Nature @cebraAI Stunning work, love seeing it out!! Congratulations!!! 🥳 🍾 🥂

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