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THE FLY BRAIN ESCAPED THE COMPUTER. I PUT IT INSIDE A PHYSICAL ROBOT. Scientists released a reconstructed map containing 166,700 neurons from a fruit fly. I connected it to a Strandbeest. The panel in the top-right shows the simulated brain running. Its neural activity is translated into motor commands... show more

Frank

2,230 subscribers

1,516,852 views • 18 hours ago •via X (Twitter)

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36 Comments

Himas17 hours ago

@Biohack_AI Terminator is back

Frank15 hours ago

@Biohack_AI After the apocalypse, flies will only look like this

sawaiz15 hours ago

Is the model running on device, or over the network. My attempt had the commands be sent and recived though my laptop.

Frank15 hours ago

Now we can replace all the flies with drones and let them keep their brains 😄

BROOKLYDAMUS14 hours ago

@sawaiz Can a digital dragonfly kill the mosquitoes in my yard

Frank14 hours ago

@sawaiz We are waiting for the dragonfly’s brain to appear in the open access 😂

Leopard Alwerfally ☣15 hours ago

welcome to digital immortality,,,,,,,, man that was based

Frank15 hours ago

Humanity will soon come to an end

James Stephens15 hours ago

What's wild is that thing is moving like a fly...start stop analysis... it's fascinating...

JangYeongSilly16 hours ago

now connect a solar panel on it's back and positively reward it for getting sunlight

Brettius Maximus14 hours ago

Put it in a roomba

Biohack AI18 hours ago

omg, it's robofly

Michael Ehrmantraut14 hours ago

@flngr Too bad the “connectome” is not perfect fidelity with the original.

Nick Longrich14 hours ago

Once we combine simulated fly brains with robotic fly bodies, seems like it's all over for fruitflies. The machines will eat the fruit far more efficiently. What are the flies supposed to do.

Deacon Santiago14 hours ago

Ah gotcha so this is how it happens huh

Travis B14 hours ago

Anyone else realize that is not the way fruit flies behave?

José Eduardo16 hours ago

This is exactly the boundary I want to explore. Making the reconstructed fly brain move a robot demonstrates coupling. The question that fascinates me is what comes next: when does movement become agency? 🪰🧠 You made the fly walk. Now I want to ask why it walks.

Allex Theofilo14 hours ago

This is like the dreadnought of flies

Valentin17 hours ago

Haha i love this fly

Jay14 hours ago

We got fly terminators before we got actual terminators

Doimo Manu14 hours ago

Have you tried to port it to the LEGO EV3 robotic set yet? You can add an array of sensors to it: sonar, RGB, IR... Tools: ev3dev for Python, BricksRL, and Cortic A.I. Toolkit (CAIT) running on RPi4 or 5.

Grievous Queef14 hours ago

and folks, you now see why you're just an antenna.......and my fucking user is a prick not paying to win.

nikhil /popcorn14 hours ago

How tf are you making these ….people are posting I made this that ….but Jo one exactly shares how ….

Maximumnoodles🏴󠁧󠁢󠁥󠁮󠁧󠁿14 hours ago

I wanna see @BostonDynamics put the fly brain into their dog robot

Sean McClure14 hours ago

Does it have sensors in the feet? Imagine trying to move around with zero tactile sensation. What we observe here is just a “confused” “brain.”

Kevin Rajan16 hours ago

how to make robot? is there a kit I can buy?

Ouroboros14 hours ago

I think it's looking for your cats litter box? --lol

neur14 hours ago

If you step on it, did you kill something.

Scaramanga14 hours ago

It resembles robocop

Kishan Bhatt™ 🇰🇪14 hours ago

Imagine being the fly and waking up in different situations and bodies every now and then wondering wtf is doing on. 😵‍💫

görk14 hours ago

now put it on a mini drone!

Zee14 hours ago

what is your github?

Elyon14 hours ago

@grok Cette expérience est-elle réelle et vérifiée ?

ᴛʀᴜᴛʜ ᴘɪʟɢʀɪᴍ14 hours ago

This is both spectacularly amazing and terrifying in what can come next.

🇺🇸 Josh 🇺🇸14 hours ago

its a reconstruction of the fly brain so you cant claim a fly did it, bc one isnt hooked up to it you're using it as a harness and acting like "this is how capable flies are" this is a deception

Noetral14 hours ago

This is beautiful! 😍

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I gave a simulated fruit fly brain access to the market. 166,700 neurons. Over 25 million connections. It trades new pairs using paper funds.

I gave a simulated fruit fly brain access to the market. 166,700 neurons. Over 25 million connections. It trades new pairs using paper funds.

CYBER_BULLY

53,034 views • 3 days ago

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182,356 views • 1 day ago

Scientists used 200,000 human brain cells to play DOOM. The cells had never seen a computer. They learned in real time. They got better. Separately: an entire fruit fly brain, 139,000 neurons, 50 million connections, was copied into a laptop. It predicts real brain responses with 90%+ accuracy. The biological computing timeline: 2021 → neurons learn Pong 2022 → fruit fly brain fully mapped 2024 → entire fly brain simulated on a laptop 2026 → human brain cells play DOOM A GPU needs ~700W to run an LLM. The brain runs the whole show on 20W. We're spending trillions on building the next giant AI training computer but what if the solution to our energy needs was just copying the technology already running in our heads?

Scientists used 200,000 human brain cells to play DOOM. The cells had never seen a computer. They learned in real time. They got better. Separately: an entire fruit fly brain, 139,000 neurons, 50 million connections, was copied into a laptop. It predicts real brain responses with 90%+ accuracy. The biological computing timeline: 2021 → neurons learn Pong 2022 → fruit fly brain fully mapped 2024 → entire fly brain simulated on a laptop 2026 → human brain cells play DOOM A GPU needs ~700W to run an LLM. The brain runs the whole show on 20W. We're spending trillions on building the next giant AI training computer but what if the solution to our energy needs was just copying the technology already running in our heads?

Josh Kale

136,752 views • 6 months ago

For the first time ever, a fruit fly brain has been trained to launch a memecoin. Not "AI inspired by a brain" — the real connectome. 165,122 neurons, 10,228,000 synaptic connections, every one traced from an actual male Drosophila by electron microscopy. Janelia FlyEM + Google Research, released CC-BY. How it works: Screenshots of the live launchpad go in through 892 retinotopic hex columns into L1 and L2 — the neurons sitting directly behind a fly's photoreceptors. All 165,122 integrate. The cursor comes back out of the descending neurons a fly actually walks with: DNa02's left-right asymmetry steers, DNa01 drives forward, DNp09 clicks. The wiring is never trained. Only synaptic gains — you don't get to invent connections the fly doesn't have. Proof its eye is doing real work: in light mode it filled 0 of 3 form fields. In dark mode, 2 of 3. Its retina is a luminance map, so invert the contrast and it goes blind. And the honest split: the fly types the description and the ticker. The rig does the name, the pair and the tax. CA: 0x4eb990547bce4a982432ca88cf5fae7eed1a2d35

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Fruit fly dev

735,266 views • 3 days ago

🪰 A team of researchers has unveiled the complete connectome of a male fruit fly central nervous system—a seamless map of all the neurons in the brain and nerve cord of a single male fruit fly and the millions of connections between them. 🔗

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HHMI | Janelia

23,891 views • 11 months ago

I gave the fruit fly brain a fruit fly body and put it into a fruit fly sim. Now you can watch him eat, fly, and shit live on

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Misch Strotz

39,509 views • 2 days ago

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hattie

9,582,695 views • 6 months ago

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77,405 views • 3 days ago

Agentic Flynance. We trained a simulated fruit fly brain to review expenses by changing just 4,184 weights. A vision model reads the receipt, then the fly decides whether to approve it. Give it a fly 🪰

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361,602 views • 1 day ago

(1/2) When Janelia set out to map every neuron in the fly brain in 2008, many thought it couldn’t be done. Nearly 20 years later, a complete wiring diagram of the 166,000+ neurons of the adult male fruit fly is helping to reveal the brain’s secrets:

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HHMI

27,633 views • 10 days ago

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BuBBliK

40,439 views • 2 days ago

The fruit fly's brain is superior to the human brain, and GPT-6 ASTRA has proven this. And the internet went crazy. Most AI models learn by training on massive datasets, running billions of computations to acquire new skills. But researchers just demonstrated a radically different approach: No giant dataset. No traditional training. Just take the physical wiring of a biological brain and simulate it in a computer. The digital fruit fly reached ~91% behavioral accuracy using only 4 things: The complete neural connectivity map Synaptic connection counts as connection weights Excitatory vs inhibitory neuron types A simple Leaky Integrate-and-Fire model The wild part? The wiring itself may contain much more of the brain’s “code” than we thought. From tens of thousands of neurons in a fly → millions in a mouse → ~86 billion in a human. If this scales, whole-brain simulation could become one of the biggest frontiers in AI. The era of biologically inspired intelligence may have just begun

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Zentrix⌚️

89,192 views • 1 day ago

Scientists have completely mapped the brain and nervous system of an adult fly for the first time — more than 166,000 neurons and millions of connections The data was made publicly available, and then things got out of hand. It seems the scientific community may already regret it. Because over the past few days, people have “taught” the fly to: — Scroll through TikTok — Drink beer — Solve a Rubik’s Cube — Parallel park — Deploy a database — Vibe-code — Fly a plane — Control a virtual human — Control a robot — Skateboard to dubstep Don’t take it literally. But it’s worth watching as the strangest tech demo of September. There’s just one catch — the fly is dead.

Scientists have completely mapped the brain and nervous system of an adult fly for the first time — more than 166,000 neurons and millions of connections The data was made publicly available, and then things got out of hand. It seems the scientific community may already regret it. Because over the past few days, people have “taught” the fly to: — Scroll through TikTok — Drink beer — Solve a Rubik’s Cube — Parallel park — Deploy a database — Vibe-code — Fly a plane — Control a virtual human — Control a robot — Skateboard to dubstep Don’t take it literally. But it’s worth watching as the strangest tech demo of September. There’s just one catch — the fly is dead.

NEXTA

85,152 views • 2 days ago

🧠 A new wiring diagram of the 166,000+ neurons in the brain & nerve cord of a male fruit fly is a key tool in uncovering how the brain enables complex behavior—information that could ultimately help scientists understand what causes different diseases ➡️

🧠 A new wiring diagram of the 166,000+ neurons in the brain & nerve cord of a male fruit fly is a key tool in uncovering how the brain enables complex behavior—information that could ultimately help scientists understand what causes different diseases ➡️

HHMI | Janelia

26,974 views • 11 months ago

We've uploaded a fruit fly. We took the FlyWire connectome of the fruit fly brain, applied a simple neuron model (Philip Shiu Nature 2024) and used it to control a MuJoCo physics-simulated body, closing the loop from neural activation to action. A few things I want to say about what this means and where we're going at eon. 🧵

We've uploaded a fruit fly. We took the FlyWire connectome of the fruit fly brain, applied a simple neuron model (Philip Shiu Nature 2024) and used it to control a MuJoCo physics-simulated body, closing the loop from neural activation to action. A few things I want to say about what this means and where we're going at eon. 🧵

Michael Andregg

1,994,846 views • 6 months ago

The full video from Cortical Labs explaining how they put 200,000 brain cells onto a silicon chip and had it play Doom is wild: “When a demon appears on the left of the screen, specific electrodes stimulate the sensory area of the neural culture on the left side. The neurons react to that stimulation. We then listen to their response, the spikes, and interpret that activity as motor commands. If the neurons fire in a specific pattern, the Doom guy shoots.”

The full video from Cortical Labs explaining how they put 200,000 brain cells onto a silicon chip and had it play Doom is wild: “When a demon appears on the left of the screen, specific electrodes stimulate the sensory area of the neural culture on the left side. The neurons react to that stimulation. We then listen to their response, the spikes, and interpret that activity as motor commands. If the neurons fire in a specific pattern, the Doom guy shoots.”

Trung Phan

233,872 views • 6 months ago

A speck in a dish—that’s all the nervous system of the fruit fly Drosophila melanogaster looks like to the naked eye. But look closely enough, and it resolves into a network of 166,700 nerve cells connected through 124.2 million synapses. The intricate map—called a connectome—has now been published, marking the end of an ambitious 20-year research project. Learn more:

A speck in a dish—that’s all the nervous system of the fruit fly Drosophila melanogaster looks like to the naked eye. But look closely enough, and it resolves into a network of 166,700 nerve cells connected through 124.2 million synapses. The intricate map—called a connectome—has now been published, marking the end of an ambitious 20-year research project. Learn more:

News from Science

28,922 views • 10 days ago

We might have just witnessed the first real mind upload. 🤯 Scientists scanned a fruit fly brain neuron by neuron, synapse by synapse, recreated it digitally, and placed it inside a simulated body. The fly walked. Groomed. Fed. No training. No prompts. No learning phase. The behavior was already in the wiring. That’s not just neuroscience anymore. That’s the first glimpse of digital minds.

We might have just witnessed the first real mind upload. 🤯 Scientists scanned a fruit fly brain neuron by neuron, synapse by synapse, recreated it digitally, and placed it inside a simulated body. The fly walked. Groomed. Fed. No training. No prompts. No learning phase. The behavior was already in the wiring. That’s not just neuroscience anymore. That’s the first glimpse of digital minds.

VraserX e/acc

862,037 views • 6 months ago

made a 3d fly that lives on my mac desktop. its brain runs a live simulation of real neurons from the FlyWire fly connectome, so it only flees my cursor when the actual escape neuron fires. it walks on window edges and naps after lunch (fr)

made a 3d fly that lives on my mac desktop. its brain runs a live simulation of real neurons from the FlyWire fly connectome, so it only flees my cursor when the actual escape neuron fires. it walks on window edges and naps after lunch (fr)

Denis Shiryaev 💙💛

12,249 views • 26 days ago

I made FlappyFly. I put a fly's brain into FlappyBird. It plays terribly. As a pipe approaches, LC4 neurons detect it getting closer. That input goes into the 166,700-neuron network, and when DNp01 fires, the wings beat. DNp01 is the giant fibre neuron that triggers a fly's escape when you try to swat it. I used that same escape circuit to get it past the pipes.

I made FlappyFly. I put a fly's brain into FlappyBird. It plays terribly. As a pipe approaches, LC4 neurons detect it getting closer. That input goes into the 166,700-neuron network, and when DNp01 fires, the wings beat. DNp01 is the giant fibre neuron that triggers a fly's escape when you try to swat it. I used that same escape circuit to get it past the pipes.

Alexey Fateev

39,705 views • 3 days ago