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The post summarizes a 2016 Temple University study published in Scientific Reports, where CRISPR/Cas9 excised HIV-1 DNA from infected human T-cells, rendering them resistant to re-infection without off-target effects. Also check out the work from leor weinberger at Gladstone Institutes on TIPs hijacking therapy! TED Talks

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Carl Freer

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15,200 просмотров • 1 год назад •via X (Twitter)

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Ha, clever idea! Grafting & mobile CRISPR for genome editing in plants. An unmodified shoot is grafted onto roots containing a mobile CRISPR/Cas9 moving from root to shoot. There it edits the plant DNA but leaves no trace of itself in the next gen! Voilà!
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Ha, clever idea! Grafting & mobile CRISPR for genome editing in plants. An unmodified shoot is grafted onto roots containing a mobile CRISPR/Cas9 moving from root to shoot. There it edits the plant DNA but leaves no trace of itself in the next gen! Voilà!

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A ribozyme that cuts DNA - programmably!! It has a ways to go before it can be a precision genome editing tool - short target recognition sequence, doesn’t bind dsDNA well - but an exciting discovery nonetheless! Study from Jun-Jie Gogo Liu lab at Tsinghua University, published in Science Magazine
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the amazing vocals from FLO’s sophomore album, “Therapy at the Club,” a thread: 1. Side Effects #TherapyattheClub
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Yes! Journal club! Our latest video in partnership with Dr. Glaucomflecken summarizes the B-Well 1 and B-Well 2 trials investigating bepirovirsen therapy for chronic hepatitis B virus infection. Read the full study for free: #hepatology
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Many people often times wonder why it is that mosquitoes transmit malaria from one person to another but same mosquito cannot transmit HIV from one person to another. I summarized the reason in this video but I will also reiterate 1. HIV cannot survive inside mosquitoes When mosquito bites someone infected with HIV, it actually picks up some of the virus . However the virus is rapidly broken down in the gut of the mosquito . Hence it does not get passed to the next person. 2. Mosquitoes do not inject previous blood into the next person When mosquitoes bite a person, they inject saliva into the person’s bite spot and this saliva is what prevents the blood from clotting while the mosquito sucks out the blood juice. It is through this process of injection of saliva that it passes Malaria , Dengue fever etc but HIV can’t be passed this way 3. HIV can only survive I specific body cells HIV needs specific body cells called CD4 cells to survive . Of course mosquito does not have those cells and HIV can thus not survive inside them. It is degraded immediately Therefore when next someone suggests that Mosquito can transmit HIV. Please feel free to give them a resounding slap on my behalf . Thank You Dr Penking

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Young women are far more likely than men of the same age, to hurt themselves on stairs. That's according to a university study published in a reputable scientific journal - which reveals the reasons why females are losing their footing. Emily Rice #9News

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