They studied 81 identical twins. Same DNA. Same childhood. Same parents. Only ONE twin got Multiple Sclerosis. Then they found the difference hiding in their poop. Two completely normal gut bacteria — Eisenbergiella tayi & Lachnoclostridium — were SKY-HIGH in every single twin with MS… and almost absent in... their healthy twin. Scientists then took those exact bacteria from the sick twins and transplanted them into mice. Result: • 60–70% of mice developed brain & spinal cord inflammation + paralysis • <10% of control mice got sick • In many cases, the bacteria exploded in numbers DAYS before the first symptoms • Female mice were hit hardest (just like real MS) This is the strongest evidence ever that MS — for a huge number of patients — may actually start in the gut. A second international study with 1,000+ people just confirmed the same two bacteria. Full 1:40 mind-blowing breakdown in the video 👇show more

Direct link: Credit: @HashemGhaili;

Identical genes but different gut bugs show your microbiome can quietly flip disease switches, so caring for your gut is basically low key immune system engineering.

MS is an autoimmune disease and like most autoimmune diseases, it’s 💯 gut related. I cured 3 supposedly incurable and 1 deadly autoimmune diseases per 7 Harvard et al trained doctors. I cure them by fixing my leaky gut and managing my gut microbiome. I refused the 5 prescription meds including steroids that the 7 doctors wanted to put me on FOR LIFE. It took 9 months to fix leaky gut with diet alone. Then another 9 months to 💯cure the 3 diseases. Diseases I was told were incurable. Shame on pill pushers!!! Shame on them.

My question is: has an effective protocol been developed and shared to cure or greatly reduce sufferer’s MS symptoms?!? 🤔

These bacteria (Eisenbergiella tayi &amp; Lachnoclostridium) feed on dietary fiber, and on mucus sugars in absence of fiber. Meat is the way to a healthy body.

So many stories of a carnivore diet reversing MS. Makes sense it stems from the gut.

Diseases start with a unhealthy gut. Doctors should stress this with all Patients.

MS is poisoning by carbs or heavy metals .

Did they try a fecal transplant from the healthy twin?

@SabinehazanMD you probably already know this, but sharing just in case. Excellent post!

MS in these twins wasn’t “fate in the DNA.” It was a corrupted signal starting in the gut and climbing the nervous system. Specific microbes distort ion gradients, mitochondrial function, and immune bioelectric signaling in the gut, sending a faulty program to the CNS via the gut–brain axis.

Have to develop toilets that measure this as an early warning system and roll them out widespread

The key question remains, WHY or HOW did they develop this particular dysbiosis? THAT'S the root cause, not the bacteria themselves. What allowed these bacteria to take hold and overpopulate the gut?

So how is it to be treated? Sterilize the gut, then repopulate it with "good" bacteria?

I hope they transplanted the healthy poop with its bacteria into the sick twins ? I’d like to know the results if so..

How do we fix this?

Bet IVM could have an impact here.

The gut-MS connection is fascinating! Makes you think twice about antibiotic overuse and the importance of good hygiene without going overboard - we need healthy gut bacteria balance, not sterile environments that might disrupt our microbiome.

I know of a female with MS. On allsorts of medications now sadly. Got worse over Covid times and drinking increased also worsening things also as you can imagine. What can be done to help her?

Thank you for sharing.

Ann Boroch, a woman who publicly claimed to have cured her own multiple sclerosis (MS) through an alternative self-help program involving a strict candida (anti-yeast) diet, died by suicide in 2017.

The identical-twin gut → MS causality paper in PNAS is a landmark, but it is walking a path that two clinicians already mapped out in real patients years ago. Thomas Borody (1950–2025) and Sabine Hazan spent the last six years of his life working shoulder-to-shoulder turning fecal microbiota transplantation (FMT) from a “weird Australian thing for ulcers and C. diff” into what is now the fastest-acting, most mechanistic therapy we have for a growing list of microbiome-driven diseases — multiple sclerosis very much included. Borody started doing FMT in 1988, long before the word “microbiome” existed in mainstream medicine. By 2011 he had already published the first case series of wheelchair-bound MS patients who walked again after his signature protocol: total bowel evacuation → pulsed broad-spectrum antibiotics → repeated high-dose donor transplants delivered by colonoscopy and enema. Remissions lasted years. Sabine Hazan took that protocol, brought it to the United States, put it under next-generation sequencing, and began asking the exact question the 2025 twin study finally proved in mice: which specific bacteria are the villains, and can we reverse the disease by replacing them wholesale? Answer: yes, and fast. Days to weeks, not months to years. Their joint work (the book Let’s Talk Sh!t, shared trials, patents, 2 a.m. phone calls, and a now-legendary retracted-then-vindicated ivermectin paper) showed that: Bifidobacteria collapse is a hallmark of MS, autism, Long COVID, Alzheimer’s — and it is reversible. Single FMTs often fail in autoimmune patients because the old flora fights back; Borody’s “evacuate-annihilate-repopulate” blitz followed by multiple infusions is what makes the new ecosystem stick. Precision donor selection (the top 1 % of humans who still carry sky-high Bifidobacteria and almost zero mucus-degrading opportunists) gives dramatically better results than random healthy-donor stool. The PNAS paper’s Eisenbergiella tayi and Lachnoclostridium overgrowth in the ileum of affected twins is exactly the pattern Borody and Hazan were already countering in clinic with screened, high-potency transplants. Borody died on 6 October 2025. Sabine Hazan’s eulogy post is still pinned on her timeline and ends with the line: “Tom’s legacy in FMT for MS lives on — now validated by twin data showing gut causality.” He saw the future thirty-five years ago. She is still building it.If you have MS (or autism, Crohn’s, Parkinson’s, or any of the other conditions now known to have a gut-trigger fingerprint), their combined body of work is the deepest, most battle-tested clinical experience on the planet. The randomised trials are coming, but the N=thousands of real-world cases are already here. Start with Borody’s 2011 MS abstract and Hazan’s 2025 ACG autism twin presentation. Then read the book they wrote together. You’ll never look at a capsule of someone else’s poop the same way again. Rest in power, Tom. Keep fighting, Sabine.

Now hopefully a treatment to resolve this is not far behind! ❤️

This explains why ivermectin works on MS

I want them to do this with Type 1 diabetes in children. We know it must start in the gut. But why do some sibs get it and not others? Also more common in kids with a Type 1 father.

Rather than infect bad bacteria to mice why not transplant good fecal bacteria into the ms child

Very good find ! Thank you for sharing this !

Interesting. I was thinking.. stress/gut. When an 🧡nt neurotypical person lives with a person who is asd:nt/asperger.... The 🧡empathetic, nt is truly affected by a parent/spouse/sibling who has a personality so different from them. The nt literally gets stomach aches from Living with a non-communicator, who lacks eye contact. The nt gets the autoim diseases. Lupus/ MS/ cancer, spine issues... stop in any group called, Cassandra, asp partners.. - Dorothy🌻

Look into epigenetics. Answers.

@SabinehazanMD 🔬 #GutFeeling

But how do we fix it?!?