632nm
@632nmPodcast • 1,364 subscribers
Technical interviews with the greatest scientists in the world. +50K on YT: https://t.co/VAMZKZAB7Z
Videos
“Almost everything you learn in biology textbooks is a hallucination.” This week we spoke with Nobel Prize-winning physicist Eric Betzig about one of the biggest challenges in biology: actually seeing what happens inside a living cell. Betzig’s work in super-resolution microscopy revealed a dynamic molecular world that often looks very different from the static picture in biology textbooks. We discuss PALM, the diffraction limit, live-cell imaging, and his ambitious Cell Observatory project to combine automated microscopy, massive datasets, and AI to understand the complexity of living cells. Full episode here on X and YouTube (see comment). Timestamps: 00:00 - Intro 01:30 - The Diffraction Limit 12:30 - Imaging Cells 19:04 - Betzig's Transition from Physics to Biology 32:37 - Getting Fed Up with Science 34:57 - Leaving Science for the Automotive Industry 55:55 - 2008 and the Fall of the Automotive Industry 1:09:50 - Building a Microscope in a Living Room 1:34:01 - Insights from Super-Resolution Microscopy 1:47:53 - AI for Analyzing Petabytes of Data 2:10:35 - Improving Microscopes 2:15:27 - Nuclear Energy and Politics 2:23:18 - The Magic of Bell Labs 2:36:17 - Is SpaceX the New Bell Labs?
632nm36,308 Aufrufe • vor 16 Tagen
We sat down with Philip Johnston, co-founder and CEO of Starcloud, at MIT to discuss why the future of data centers might be in space. After graduating Y Combinator less than 2 years ago, Starcloud just raised an impressive $170M Series A at a $1.1B valuation led by Benchmark and EQT Ventures & Growth. The conversation covers everything from solar physics and cooling systems to GPU economics, radiation hardening, launch costs, and satellite design. Philip also shares what it takes to build a unicorn deeptech startup. We discuss his experience with YC, the skepticism around their demoday launch, and the crazy last minute race to get Starcloud’s first satellite onboard their scheduled Falcon flight. Full episode is here on X and at any of the links below (see comment). Timestamps: 00:00 - Intro 01:12 - What is Starcloud? 02:44 - Why do data centers need to go to space? 06:15 - Can’t we just build more solar panels on earth? 11:10 - Economic analysis of Starcloud 19:56 - How does Starcloud’s cooling work? 28:26 - Training an LLM in space 32:07 - Addressing critics on space Twitter 34:23 - Is Starcloud overfunded? 35:59 - Will demand for data centers keep going up? 38:11 - GPU lifespan and disposal in space 39:47 - Bus structures 41:43 - Starcloud’s origin and founders 49:29 - Fundraising, Competition, and Meeting Expectations 53:29 - Satellite size and collisions 56:29 - Manufacturing Bottlenecks 1:00:20 - Starcloud 1 tests 1:01:57 - Acceleration after YC 1:03:43 - Testing on Earth 1:05:06 - Motivations for Starcloud 1:06:45 - Data centers on the Moon 1:08:12 - Interacting with AI companies 1:08:18 - What’s next for Starcloud? 1:14:01 - Other uses for Starcloud satellites 1:17:56 - Lunar hotels and space elevators 1:24:28 - Complementary business ideas to Starcloud 1:29:51 - Philip’s competitive twin 1:32:18 - Philip and Mike’s thoughts on YC 1:36:04 - Advice for young entrepreneurs Elon Musk Scott Manley Kyle Hill Hank Green
632nm46,599 Aufrufe • vor 5 Monaten
We sat down with Michael Levin, developmental biologist at Tufts University, about the emerging field of developmental bioelectricity: how electrical signals help control how organisms build and regenerate themselves. Levin explains how voltage gradients, ion channels, and gap junctions guide embryonic development and encode large-scale anatomical information that cells use to determine what structures to build. We also discuss two-headed planarian worms, ectopic eye formation, regenerative medicine, morphogenesis, and why bioelectricity may represent a layer of biological control that exists beyond genes alone. Full episode is here on X and at the links below (see comment). Timestamps: 00:00 - Intro 01:40 - Early Interest in Bioelectricity 05:22 - External Electric Stimulation 19:54 - Two-Headed Planarians 31:40 - Designing Bioelectric Experimental Methods 56:37 - Different Model Organisms 1:07:34 - TAME Theory 1:24:16 - Xenobots and Advice for Young Scientists
632nm19,515 Aufrufe • vor 3 Monaten
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