Dr. Alex Tatem
@DrAlexTatem • 17,373 subscribers
Board Certified Men’s Health Urologist specializing in TRT, Penile Implant Surgery, Male Fertility, Erectile Dysfunction, and Vasectomy Reversal at @UrologyofIN
Videos
The “steroid killer” might finally be real. Myostatin inhibitors are doing something we’ve never really had a drug do before: Lose fat. Preserve muscle. And potentially increase lean mass. Apitegromab. Bimagrumab. Trevogrumab. Garetosmab. The data is getting VERY interesting—but there’s a massive catch almost nobody is talking about. Here’s everything we know so far 👇
Dr. Alex Tatem72,032 görüntüleme • 9 gün önce
Most TRT clinics give you one testosterone shot a week. I inject every day. Not more testosterone. The same weekly dose, divided into much smaller injections. Why? Fewer dramatic peaks and troughs—and a much flatter week. Here’s why injection frequency can completely change your TRT experience:
Dr. Alex Tatem33,288 görüntüleme • 5 gün önce
Clav’s stack is absolutely wild. Testosterone. Reta. Dutasteride. Minoxidil. Emsam. Nebivolol. Tadalafil. Do I recommend it? No. But pretending people can’t get these drugs without a doctor doesn’t make anyone safer. You can’t harm-reduce something you refuse to talk about. Welcome to medicine in 2026.
Dr. Alex Tatem92,696 görüntüleme • 26 gün önce
Retatrutide just posted Phase 3 numbers that are hard to ignore. ~30% average body weight loss. ~70 pounds lost. Even the lowest dose outperformed what used to be considered best-in-class. But the most interesting part of the story isn't the weight loss. It's the thousands of people already using grey-market Retatrutide before there's an approved pharmacy version available. What did the trials actually do? What dose produced the best balance of results and tolerability? And why might the biggest risk have nothing to do with the drug itself?
Dr. Alex Tatem232,738 görüntüleme • 3 ay önce
This is the COMPLETE Peptide Tier List compilation — Parts 1 through 3 combined into one deep dive. We break down the most talked-about compounds in fitness, longevity, anti-aging, and fat loss: Semaglutide, Tirzepatide, Retatrutide, Mazdutide, Growth Hormone (HGH), HCG, IGF-1 LR3, Tesamorelin, Sermorelin, CJC-1295, Ipamorelin, BPC-157, TB-500, NAD+, Melanotan, Selank, SEMAX, MOTS-C, Kisspeptin, Insulin, and more. If you’ve ever searched: • Best peptides for fat loss • Best peptide for muscle growth • GLP-1 vs growth hormone • Is BPC-157 legit? • Is insulin dangerous for bodybuilding? This thread answers it. We cover: ✔️ Real human data vs hype ✔️ Fat loss vs muscle-building compounds ✔️ GLP-1 agonists (semaglutide, tirzepatide, retatrutide) ✔️ Growth hormone secretagogues ✔️ Longevity + nootropic peptides ✔️ The compounds people massively overestimate Some are revolutionary. Some are promising. Some are pure internet fantasy. This isn’t bro science. It’s mechanism + data + real-world application. If you’re considering peptides for weight loss, muscle gain, performance, anti-aging, or cognition — read this before you inject anything. 👇 Which compound surprised you the most?
Dr. Alex Tatem290,149 görüntüleme • 6 ay önce
Primobolan might be the most elegant anabolic steroid ever made. No estrogen. No DHT amplification. Higher androgen receptor affinity than testosterone. It was once considered gentle enough to give to premature infants. So why did it disappear from medicine—and why is it now one of the most expensive and counterfeited steroids in bodybuilding? I went all the way back to the human trials, receptor data, side effects, black-market testing, and a wild new muscle receptor discovered in 2025. The deeper I went, the stranger Primo got. Full Primobolan deep dive 👇
Dr. Alex Tatem35,394 görüntüleme • 24 gün önce
NAD+ has been studied since 1906. It has 2 Nobel Prizes, randomized human trials, and over a century of biochemistry behind it. Yet in 2017, the FDA advisory committee voted against adding it to the 503A bulks list. The reason wasn't what most people think.
Dr. Alex Tatem37,058 görüntüleme • 1 ay önce
Today I testified before the FDA's Pharmacy Compounding Advisory Committee to advocate for patient access to BPC-157, TB-500, KPV, and MOTS-c. The committee voted to recommend moving all four peptides forward—but this is not final FDA approval. There are still important steps ahead. I break down exactly what happened, what this vote actually means, and what comes next.👇
Dr. Alex Tatem44,501 görüntüleme • 1 ay önce
SS-31 might be the most misunderstood peptide in the longevity world. ✅ Incredible cell data. ✅ Incredible mouse data. ❌ Multiple failed human trials. ...and yet it still became the first FDA-approved mitochondria-targeting medicine. How can all of those things be true at once? Full breakdown below. 👇
Dr. Alex Tatem37,793 görüntüleme • 1 ay önce
BPC-157 causing cancer? FDA shutting down peptide trials? “No human RCTs have ever been done on peptides?” In this video, Dr. Alex Tatem — board-certified urologist and fellowship-trained men’s health specialist — reacts to viral claims made on Shawn Ryan Show about BPC-157, TB-500, peptides, angiogenesis, cancer risk, and peptide safety. We break down: • Whether BPC-157 actually causes cancer • The truth about angiogenesis and tumor growth • FDA regulation of peptides and compounding • Why the “no randomized controlled trials” claim is completely false • Human clinical trial data on peptides • The real history of BPC-157 clinical studies • Huberman’s correction of viral peptide misinformation • Why peptide fearmongering could push patients toward unsafe gray-market sourcing This is not bro-science or influencer hype. This is a deep dive into the actual published literature, peptide pharmacology, FDA policy, and performance medicine. Topics covered include: BPC-157, TB-500, peptides, angiogenesis, cancer biology, GLP-1 drugs, Ozempic, tirzepatide, semaglutide, TRT, peptide therapy, biohacking, longevity, anti-aging medicine, compounding pharmacies, peptide legality, Andrew D. Huberman, Ph.D. , Shawn Ryan Show, FDA peptide regulation, growth hormone history, and performance medicine. If you’ve ever wondered whether BPC-157 is dangerous, whether peptides are legal, or whether the internet is fearmongering about peptide therapy — this video is for you.
Dr. Alex Tatem77,608 görüntüleme • 3 ay önce
I promise I'm still Team Reta. 😂 But this might be its most underrated benefit. Lilly built retatrutide to shrink body fat. Instead, it accidentally produced one of the largest liver fat reductions ever reported: • 82% reduction in liver fat • 86% returned to normal liver fat levels Important caveat: this was liver fat, not proof it reverses liver scarring. Phase 3 biopsy trials are still underway. Sometimes the best discoveries are the ones nobody was trying to make.
Dr. Alex Tatem25,727 görüntüleme • 1 ay önce
Everyone knows Deca. Almost nobody knows nandrolone. It's one of the few anabolic steroids with decades of human clinical data, FDA approval, and legitimate medical use. But that doesn't mean it's harmless. We cover the real evidence behind muscle growth, joint pain, fertility, cardiovascular risk, TRT, and the infamous "Deca Dick." The internet has had this compound wrong for years. Watch the full breakdown below. Thanks to Rugiet Health for sponsoring today’s video! And to our non-sponsors Yapper from TJ Bongiorno and Alp Pouch for powering the recording session. 📷
Dr. Alex Tatem26,414 görüntüleme • 1 ay önce
Everyone wants the fountain of youth. The internet thinks it comes in a peptide vial called Epitalon. It supposedly lengthens telomeres, activates telomerase, improves sleep, and maybe even slows aging itself. But when you actually read the research... The story gets a lot more interesting. We dug through the Cold War origins, the Russian longevity studies, the cancer concerns, the sleep data, and what the evidence really says about one of the most hyped peptides in biohacking. If you've ever wondered whether Epitalon is the closest thing we have to an anti-aging therapy—or just another internet myth—this one's for you. Abud Bakri MD
Dr. Alex Tatem30,634 görüntüleme • 2 ay önce
Enclomiphene has become one of the most prescribed men's health drugs in America. It raises testosterone. It preserves fertility. It isn't a controlled substance. So why did it fail FDA approval? In this deep dive, I break down the actual evidence, who it's great for, why it leaves some men feeling incredible and others feeling nothing, and where the marketing gets ahead of the science. This one's dedicated to two people: Dr. Cameron Maximus🤴🏻 🥷🏻 🧙🏻♂️ 🤵♂️ , who loves enclomiphene... ...and CoffeeBlackMD , who hates it. Now fight in the comments. 🍿 Watch the full video below. 👇
Dr. Alex Tatem31,848 görüntüleme • 2 ay önce
The testosterone booster industry did about $6 billion last year. Most of it is built on one assumption: "There's a study" = "It actually works." Those are not the same thing. In this video, I ranked the biggest natural testosterone boosters by one metric only: How much they actually move testosterone levels in real human studies. Tongkat Ali. Ashwagandha. Shilajit. Boron. Zinc. Some surprised me. One nearly doubled testosterone levels. Most of the industry probably won't like where it landed. Watch here 👇
Dr. Alex Tatem12,900 görüntüleme • 2 ay önce
Imagine a compound that claims to improve focus, boost learning, increase BDNF, and even help protect the brain after a stroke. Sounds like science fiction. It's called Semax—a peptide developed in the Soviet Union that's been used clinically in Russia for over 30 years. So... is it actually a real brain booster? In this video I break down: • The actual human and animal data • How Semax works • Whether it can really make you "smarter" • Side effects and safety • The biggest risk most people completely overlook: the bottle it's coming from I also cover the upcoming FDA PCAC meeting that could determine the future of legal access to Semax and several other peptides in the U.S. If you're interested in evidence—not hype—this one's for you. Have you tried Semax? Did it help your focus, or did you feel absolutely nothing? Let me know below. 👇
Dr. Alex Tatem11,437 görüntüleme • 2 ay önce
BPC-157 and TB-500 are two of the most talked-about peptides in fitness, bodybuilding, and biohacking. Together they’re often called the “Wolverine Stack” — a peptide combination rumored to dramatically accelerate healing of tendons, ligaments, muscles, and injuries. But do BPC-157 and TB-500 actually work in humans, or is the Wolverine Stack just another example of internet bro-science? In this evidence-based deep dive, Dr. Alex Tatem (board-certified urologist and men’s health specialist) breaks down the real science behind BPC-157 and TB-500 — including their biochemical mechanisms, animal research, potential healing effects, safety concerns, and why pharmaceutical companies have never brought these peptides through full FDA clinical trials. We explore the nitric oxide signaling, angiogenesis, VEGF pathways, actin regulation, and tissue repair biology behind these compounds and explain why rodent studies look promising — but why human clinical evidence is still extremely limited. You’ll also learn about: • What BPC-157 (Body Protection Compound-157) actually is • TB-500 vs Thymosin Beta-4 explained • The origin of the Wolverine Stack peptide protocol • Peptides for tendon healing and ligament injuries • BPC-157 for gut healing and musculoskeletal repair • TB-500 and actin-mediated tissue regeneration • Why most peptide research comes from one Croatian research group • The patent law problem preventing pharmaceutical development • Real risks of grey-market peptide contamination • Why WADA bans BPC-157 and TB-500 in competitive athletes • Theoretical cancer risks related to angiogenesis • What the current scientific literature actually shows If you've ever searched: “Does BPC-157 work?” “What is TB-500?” “Peptides for healing injuries” “BPC-157 tendon repair” “Wolverine Stack peptides explained” — this video breaks down the science. The peptides may be promising. But promise and proof are not the same thing. Drop a comment below: Have you ever used BPC-157, TB-500, or other peptides? What was your experience? 👍 Like the video if you want more evidence-based breakdowns of supplements, PEDs, and peptides. Subscribe for deep dives on testosterone, steroids, peptides, supplements, and men’s health science.
Dr. Alex Tatem22,765 görüntüleme • 6 ay önce
Daha fazla içerik yok.