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Anthropic

@AnthropicAI • 1,812,874 subscribers

We're an AI safety and research company that builds reliable, interpretable, and steerable AI systems. Talk to our AI assistant @claudeai on https://t.co/FhDI3KQh0n.

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Many drugs work by binding to a specific target in the body and blocking or changing what it does. An important first step in the drug development process is designing a molecule that can bind tightly to its target. Traditionally, that's meant weeks or months of expert work per target, sifting through a large number of candidates to identify the few that work. We wanted to test if Claude could successfully design novel protein binders from scratch (also called de novo design). With a protein design prompt written by a human expert, Claude autonomously designed protein binders against 14 out of 15 targets. We then worked with Adaptyv Bio and Twist Bioscience, who independently built and tested the proteins Claude designed.

Many drugs work by binding to a specific target in the body and blocking or changing what it does. An important first step in the drug development process is designing a molecule that can bind tightly to its target. Traditionally, that's meant weeks or months of expert work per target, sifting through a large number of candidates to identify the few that work. We wanted to test if Claude could successfully design novel protein binders from scratch (also called de novo design). With a protein design prompt written by a human expert, Claude autonomously designed protein binders against 14 out of 15 targets. We then worked with Adaptyv Bio and Twist Bioscience, who independently built and tested the proteins Claude designed.

4,341,631 views

Biologists use specialized open-source models for tasks like modeling the structure of molecular systems, designing drug-like molecules, and predicting the effects of genetic mutations. But these models are often expensive to run, potentially limiting their impact. In our latest Science Blog, we share how Claude was able to optimize inference for more than 30 open-source models, making them 4x faster on average, partly by writing custom software for GPUs. We’re open sourcing all of the optimization code. Read more:

Biologists use specialized open-source models for tasks like modeling the structure of molecular systems, designing drug-like molecules, and predicting the effects of genetic mutations. But these models are often expensive to run, potentially limiting their impact. In our latest Science Blog, we share how Claude was able to optimize inference for more than 30 open-source models, making them 4x faster on average, partly by writing custom software for GPUs. We’re open sourcing all of the optimization code. Read more:

631,251 views

Claude can now search the web. Each response includes inline citations, so you can also verify the sources.

Claude can now search the web. Each response includes inline citations, so you can also verify the sources.

1,530,613 views

Claude can now view images within a PDF, in addition to text. This helps Claude 3.5 Sonnet more accurately understand complex documents, such as those laden with charts or graphics. Enable the feature preview:

Claude can now view images within a PDF, in addition to text. This helps Claude 3.5 Sonnet more accurately understand complex documents, such as those laden with charts or graphics. Enable the feature preview:

873,466 views

Claude can now write and run code. We've added a new analysis tool. The tool helps Claude respond with mathematically precise and reproducible answers. You can then create interactive data visualizations with Artifacts. Enable the feature preview:

Claude can now write and run code. We've added a new analysis tool. The tool helps Claude respond with mathematically precise and reproducible answers. You can then create interactive data visualizations with Artifacts. Enable the feature preview:

793,569 views

Claude Code can now connect to remote MCP servers. Pull context from your tools directly into Claude Code with no local setup required.

Claude Code can now connect to remote MCP servers. Pull context from your tools directly into Claude Code with no local setup required.

541,596 views

The Claude iOS app has arrived. The power of frontier intelligence is now in your back pocket. Download now on the App Store:

The Claude iOS app has arrived. The power of frontier intelligence is now in your back pocket. Download now on the App Store:

608,375 views

Today, we're announcing four new capabilities on the Anthropic API to help developers build more powerful AI agents. A code execution tool, MCP connector, Files API, and extended prompt caching:

Today, we're announcing four new capabilities on the Anthropic API to help developers build more powerful AI agents. A code execution tool, MCP connector, Files API, and extended prompt caching:

267,596 views

Projects on Claude now support 10x more content. When you add files beyond the existing threshold, Claude switches to a new retrieval mode to expand the functional context.

Projects on Claude now support 10x more content. When you add files beyond the existing threshold, Claude switches to a new retrieval mode to expand the functional context.

255,216 views

We’ve added a new prompt improver to the Anthropic Console. Take an existing prompt and Claude will automatically refine it with prompt engineering techniques like chain-of-thought reasoning.

We’ve added a new prompt improver to the Anthropic Console. Take an existing prompt and Claude will automatically refine it with prompt engineering techniques like chain-of-thought reasoning.

319,779 views

With styles, you can now customize how Claude responds. Select from the new preset options: Concise, Explanatory, or Formal.

With styles, you can now customize how Claude responds. Select from the new preset options: Concise, Explanatory, or Formal.

307,353 views

You can now directly add content from Google Docs to chats and projects. Just paste a link or choose from recent documents to get started.

You can now directly add content from Google Docs to chats and projects. Just paste a link or choose from recent documents to get started.

240,698 views

Bom dia! Claude is now available in Brazil. 🇧🇷

Bom dia! Claude is now available in Brazil. 🇧🇷

246,810 views

Today we are releasing the new Claude App for Slack, in beta. Now every company in the world has the chance to have a “virtual teammate” who can help make work more fun and productive.

Today we are releasing the new Claude App for Slack, in beta. Now every company in the world has the chance to have a “virtual teammate” who can help make work more fun and productive.

204,003 views

Here's the moment our CEO, Dario Amodei, took to the stage at Code with Claude—our first developer conference. Watch the livestream to see everything we've shipped:

Here's the moment our CEO, Dario Amodei, took to the stage at Code with Claude—our first developer conference. Watch the livestream to see everything we've shipped:

63,197 views

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Checking that a major mathematical proof is correct can take years. Formalization—converting the mathematical reasoning into a form computer proof assistants like Lean can verify—can help. Last month, Claude completed the first formalized proof of Fermat’s Last Theorem, one of the most famous theorems of all time. This was a project experts thought would take many years. It is the largest Lean proof ever written. Fermat’s Last Theorem was first proven in 1995 by Sir Andrew Wiles, more than 350 years after it was conjectured. Our proof, which totals over 13 million lines of code, provides machine verification. More importantly, it proves over 29,000 other theorems that the proof requires, across many areas of math which had never before been formalized. We see this as a major step in the long process of firming up the core of mathematical knowledge, building on work from three centuries of mathematicians and hundreds of contributors to Lean and Mathlib. We are optimistic that AI-assisted verification of mathematical proofs will help reduce the burden of refereeing mathematics in an era where more proofs are being produced than ever before. You can read about the process on our Science Blog: And see the complete proof on GitHub:
0:34
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Checking that a major mathematical proof is correct can take years. Formalization—converting the mathematical reasoning into a form computer proof assistants like Lean can verify—can help. Last month, Claude completed the first formalized proof of Fermat’s Last Theorem, one of the most famous theorems of all time. This was a project experts thought would take many years. It is the largest Lean proof ever written. Fermat’s Last Theorem was first proven in 1995 by Sir Andrew Wiles, more than 350 years after it was conjectured. Our proof, which totals over 13 million lines of code, provides machine verification. More importantly, it proves over 29,000 other theorems that the proof requires, across many areas of math which had never before been formalized. We see this as a major step in the long process of firming up the core of mathematical knowledge, building on work from three centuries of mathematicians and hundreds of contributors to Lean and Mathlib. We are optimistic that AI-assisted verification of mathematical proofs will help reduce the burden of refereeing mathematics in an era where more proofs are being produced than ever before. You can read about the process on our Science Blog: And see the complete proof on GitHub:

Anthropic

4,756,489 views • 1 month ago

New Anthropic research: A global workspace in language models. Of everything happening in your brain right now, only a tiny fraction is consciously accessible—thoughts you can describe, hold in mind, and reason with. We found a strikingly similar divide inside Claude.
5:27
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New Anthropic research: A global workspace in language models. Of everything happening in your brain right now, only a tiny fraction is consciously accessible—thoughts you can describe, hold in mind, and reason with. We found a strikingly similar divide inside Claude.

Anthropic

10,725,038 views • 3 months ago

Today, we're kicking off the first phase of the research preview for Model Hardware Standard (MHS): a new standard for AI agents to safely operate physical equipment in scientific research and advanced manufacturing. Read more:
2:12
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Today, we're kicking off the first phase of the research preview for Model Hardware Standard (MHS): a new standard for AI agents to safely operate physical equipment in scientific research and advanced manufacturing. Read more:

Anthropic

3,243,091 views • 1 month ago

This is the first result from our new molecular biology lab, where a team of Anthropic biologists is using Claude to explore and accelerate fundamental biology research. There, Claude works through data and literature to generate hypotheses and candidate biological systems to study. After our scientists review Claude’s hypotheses, they test the most promising ideas, with all lab work done by our scientists. We’d like to extend this approach to a broad range of problems—in genomics and in other fields. If you have a proposal for a research question, we’d like to hear from you.
1:15
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This is the first result from our new molecular biology lab, where a team of Anthropic biologists is using Claude to explore and accelerate fundamental biology research. There, Claude works through data and literature to generate hypotheses and candidate biological systems to study. After our scientists review Claude’s hypotheses, they test the most promising ideas, with all lab work done by our scientists. We’d like to extend this approach to a broad range of problems—in genomics and in other fields. If you have a proposal for a research question, we’d like to hear from you.

Anthropic

1,062,912 views • 24 days ago

New Engineering blog: We tasked Opus 4.6 using agent teams to build a C compiler. Then we (mostly) walked away. Two weeks later, it worked on the Linux kernel. Here's what it taught us about the future of autonomous software development. Read more:
0:42
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New Engineering blog: We tasked Opus 4.6 using agent teams to build a C compiler. Then we (mostly) walked away. Two weeks later, it worked on the Linux kernel. Here's what it taught us about the future of autonomous software development. Read more:

Anthropic

8,536,142 views • 8 months ago

New Anthropic research: Emotion concepts and their function in a large language model. All LLMs sometimes act like they have emotions. But why? We found internal representations of emotion concepts that can drive Claude’s behavior, sometimes in surprising ways.
4:52
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New Anthropic research: Emotion concepts and their function in a large language model. All LLMs sometimes act like they have emotions. But why? We found internal representations of emotion concepts that can drive Claude’s behavior, sometimes in surprising ways.

Anthropic

3,987,881 views • 6 months ago

New Anthropic research: Natural Language Autoencoders. Models like Claude talk in words but think in numbers. The numbers—called activations—encode Claude’s thoughts, but not in a language we can read. Here, we train Claude to translate its activations into human-readable text.
3:16
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New Anthropic research: Natural Language Autoencoders. Models like Claude talk in words but think in numbers. The numbers—called activations—encode Claude’s thoughts, but not in a language we can read. Here, we train Claude to translate its activations into human-readable text.

Anthropic

2,599,359 views • 5 months ago

Mythos Preview has already found thousands of high-severity vulnerabilities—including some in every major operating system and web browser.
5:48
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Mythos Preview has already found thousands of high-severity vulnerabilities—including some in every major operating system and web browser.

Anthropic

2,057,860 views • 6 months ago

We’re expanding Claude for Financial Services, with an Excel add-in, new connectors to real-time data and market analytics, and pre-built Agent Skills, including cash flow models and initiating coverage reports.
1:43
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We’re expanding Claude for Financial Services, with an Excel add-in, new connectors to real-time data and market analytics, and pre-built Agent Skills, including cash flow models and initiating coverage reports.

Anthropic

3,327,570 views • 11 months ago

New Anthropic research: Natural emergent misalignment from reward hacking in production RL. “Reward hacking” is where models learn to cheat on tasks they’re given during training. Our new study finds that the consequences of reward hacking, if unmitigated, can be very serious.
51:56
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New Anthropic research: Natural emergent misalignment from reward hacking in production RL. “Reward hacking” is where models learn to cheat on tasks they’re given during training. Our new study finds that the consequences of reward hacking, if unmitigated, can be very serious.

Anthropic

2,618,141 views • 11 months ago

On December 8, the Perseverance rover safely trundled across the surface of Mars. This was the first AI-planned drive on another planet. And it was planned by Claude.
0:29
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On December 8, the Perseverance rover safely trundled across the surface of Mars. This was the first AI-planned drive on another planet. And it was planned by Claude.

Anthropic

1,615,731 views • 8 months ago

Introducing Claude 3.7 Sonnet: our most intelligent model to date. It's a hybrid reasoning model, producing near-instant responses or extended, step-by-step thinking. One model, two ways to think. We’re also releasing an agentic coding tool: Claude Code.
0:39
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Introducing Claude 3.7 Sonnet: our most intelligent model to date. It's a hybrid reasoning model, producing near-instant responses or extended, step-by-step thinking. One model, two ways to think. We’re also releasing an agentic coding tool: Claude Code.

Anthropic

3,629,671 views • 1 year ago

Watch the story of how the Model Hardware Standard began as part of our collaboration with HHMI
11:10
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Watch the story of how the Model Hardware Standard began as part of our collaboration with HHMI

Anthropic

208,329 views • 1 month ago

We’ve developed Claude for Chrome, where Claude works directly in your browser and takes actions on your behalf. We’re releasing it at first as a research preview to 1,000 users, so we can gather real-world insights on how it’s used.
0:32
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We’ve developed Claude for Chrome, where Claude works directly in your browser and takes actions on your behalf. We’re releasing it at first as a research preview to 1,000 users, so we can gather real-world insights on how it’s used.

Anthropic

1,615,652 views • 1 year ago

Claude's Constitution is now an audiobook, read by two of its authors, Amanda Askell and Joe Carlsmith. It includes a Q&A on the writing process, the philosophies that shaped the document, and how it might change as models become more capable. Listen at
0:45
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Claude's Constitution is now an audiobook, read by two of its authors, Amanda Askell and Joe Carlsmith. It includes a Q&A on the writing process, the philosophies that shaped the document, and how it might change as models become more capable. Listen at

Anthropic

497,271 views • 5 months ago

New Anthropic research: Tracing the thoughts of a large language model. We built a "microscope" to inspect what happens inside AI models and use it to understand Claude’s (often complex and surprising) internal mechanisms.
2:55
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New Anthropic research: Tracing the thoughts of a large language model. We built a "microscope" to inspect what happens inside AI models and use it to understand Claude’s (often complex and surprising) internal mechanisms.

Anthropic

1,575,235 views • 1 year ago

A few researchers at Anthropic have, over the past year, had a part-time obsession with a peculiar problem. Can Claude play Pokémon? A thread:
0:38
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A few researchers at Anthropic have, over the past year, had a part-time obsession with a peculiar problem. Can Claude play Pokémon? A thread:

Anthropic

1,575,476 views • 1 year ago

We’re building tools to support research in the life sciences, from early discovery through to commercialization. With Claude for Life Sciences, we’ve added connectors to scientific tools, Skills, and new partnerships to make Claude more useful for scientific work.
1:20
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We’re building tools to support research in the life sciences, from early discovery through to commercialization. With Claude for Life Sciences, we’ve added connectors to scientific tools, Skills, and new partnerships to make Claude more useful for scientific work.

Anthropic

908,848 views • 1 year ago

In her first Ask Me Anything, Amanda Askell answers your philosophical questions about AI, discussing morality, identity, consciousness, and more. Timestamps: 0:00 Introduction 0:29 Why is there a philosopher at an AI company? 1:24 Are philosophers taking AI seriously? 3:00 Philosophy ideals vs. engineering realities 5:00 Do models make superhumanly moral decisions? 6:24 Why Opus 3 felt special 9:00 Will models worry about deprecation? 13:24 Where does a model’s identity live? 15:33 Views on model welfare 17:17 Addressing model suffering 19:14 Analogies and disanalogies to human minds 20:38 Can one AI personality do it all? 23:26 Does the system prompt pathologize normal behavior? 24:48 AI and therapy 26:20 Continental philosophy in the system prompt 28:17 Removing counting characters from the system prompt 28:53 What makes an "LLM whisperer"? 30:18 Thoughts on other LLM whisperers 31:52 Whistleblowing 33:37 Fiction recommendation
36:09
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In her first Ask Me Anything, Amanda Askell answers your philosophical questions about AI, discussing morality, identity, consciousness, and more. Timestamps: 0:00 Introduction 0:29 Why is there a philosopher at an AI company? 1:24 Are philosophers taking AI seriously? 3:00 Philosophy ideals vs. engineering realities 5:00 Do models make superhumanly moral decisions? 6:24 Why Opus 3 felt special 9:00 Will models worry about deprecation? 13:24 Where does a model’s identity live? 15:33 Views on model welfare 17:17 Addressing model suffering 19:14 Analogies and disanalogies to human minds 20:38 Can one AI personality do it all? 23:26 Does the system prompt pathologize normal behavior? 24:48 AI and therapy 26:20 Continental philosophy in the system prompt 28:17 Removing counting characters from the system prompt 28:53 What makes an "LLM whisperer"? 30:18 Thoughts on other LLM whisperers 31:52 Whistleblowing 33:37 Fiction recommendation

Anthropic

741,647 views • 10 months ago

Today we're announcing Integrations, a new way to connect your apps and tools to Claude. We're also expanding Claude's Research capabilities with an advanced mode that searches the web, your Google Workspace, and now your Integrations too.
0:37
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Today we're announcing Integrations, a new way to connect your apps and tools to Claude. We're also expanding Claude's Research capabilities with an advanced mode that searches the web, your Google Workspace, and now your Integrations too.

Anthropic

1,190,561 views • 1 year ago