Colossal Biosciences®'s banner
Colossal Biosciences®'s profile picture

Colossal Biosciences®

@colossal • 339,691 subscribers

The de-extinction company.

Shorts

SOUND ON. You’re hearing the first howl of a dire wolf in over 10,000 years. Meet Romulus and Remus—the world’s first de-extinct animals, born on October 1, 2024. The dire wolf has been extinct for over 10,000 years. These two wolves were brought back from extinction using genetic edits derived from a complete dire wolf genome, meticulously reconstructed by Colossal from ancient DNA found in fossils dating back 11,500 and 72,000 years. This moment marks not only a milestone for us as a company but also a leap forward for science, conservation, and humanity. From the beginning, our goal has been clear: “To revolutionize history and be the first company to use CRISPR technology successfully in the de-extinction of previously lost species.” By achieving this, we continue to push forward our broader mission on—accepting humanity’s duty to restore Earth to a healthier state. But this isn’t just our moment—it’s one for science, our planet, and humankind. All of which we love and are passionate about. Now, close your eyes and listen to that howl once more. Think about what this means for all of us.

SOUND ON. You’re hearing the first howl of a dire wolf in over 10,000 years. Meet Romulus and Remus—the world’s first de-extinct animals, born on October 1, 2024. The dire wolf has been extinct for over 10,000 years. These two wolves were brought back from extinction using genetic edits derived from a complete dire wolf genome, meticulously reconstructed by Colossal from ancient DNA found in fossils dating back 11,500 and 72,000 years. This moment marks not only a milestone for us as a company but also a leap forward for science, conservation, and humanity. From the beginning, our goal has been clear: “To revolutionize history and be the first company to use CRISPR technology successfully in the de-extinction of previously lost species.” By achieving this, we continue to push forward our broader mission on—accepting humanity’s duty to restore Earth to a healthier state. But this isn’t just our moment—it’s one for science, our planet, and humankind. All of which we love and are passionate about. Now, close your eyes and listen to that howl once more. Think about what this means for all of us.

28,498,770 views

BREAKING: We're bringing back DRAGONS! The Victorian grassland earless dragon was extinct in the wild. Now it's returning thanks to breakthrough genetics. Follow for the wildest science on Earth.

BREAKING: We're bringing back DRAGONS! The Victorian grassland earless dragon was extinct in the wild. Now it's returning thanks to breakthrough genetics. Follow for the wildest science on Earth.

8,401,816 views

Whakataukī are ancestral Māori proverbs, short poetic sayings passed down through generations. Rich in metaphor and meaning, they spark reflection and guide growth. Many reference the moa. Here are a few of our favorites. May the moa eat again. (1/9)

Whakataukī are ancestral Māori proverbs, short poetic sayings passed down through generations. Rich in metaphor and meaning, they spark reflection and guide growth. Many reference the moa. Here are a few of our favorites. May the moa eat again. (1/9)

218,386 views

Why do we pour time, tech, money and way too many granola bars into this work? Because extinction isn’t just their loss. It’s ours too. Every species saved is a win for the whole planet. Support conservation, in all its forms.

Why do we pour time, tech, money and way too many granola bars into this work? Because extinction isn’t just their loss. It’s ours too. Every species saved is a win for the whole planet. Support conservation, in all its forms.

184,186 views

🤯 You’re looking at pigeon primordial germ cells (PGCs) grown in culture for the first time. These stem cells will be key to bringing back the dodo. Until now, this achievement was limited to chickens and geese, but unlocking it in pigeons opens the door to dodo de-extinction.

🤯 You’re looking at pigeon primordial germ cells (PGCs) grown in culture for the first time. These stem cells will be key to bringing back the dodo. Until now, this achievement was limited to chickens and geese, but unlocking it in pigeons opens the door to dodo de-extinction.

110,665 views

Heave ho, let's go! This look like you and your sibling fighting over the last bagel bite? The Colossal dire wolves got into a little game of tug of war when learning how to skin and share a whole deer. You think they liked it?

Heave ho, let's go! This look like you and your sibling fighting over the last bagel bite? The Colossal dire wolves got into a little game of tug of war when learning how to skin and share a whole deer. You think they liked it?

23,907 views

Emus can’t fly, but they can sprint up to 31 mph(50 km/h). So why’s this chick so hyped? Because we just announced our newest de-extinction project: the South Island giant moa. And if you hadn’t seen your cousin in 400 years, you’d be freaking out too. 🎥HikeNSnorkel r/Eyebleach

Emus can’t fly, but they can sprint up to 31 mph(50 km/h). So why’s this chick so hyped? Because we just announced our newest de-extinction project: the South Island giant moa. And if you hadn’t seen your cousin in 400 years, you’d be freaking out too. 🎥HikeNSnorkel r/Eyebleach

99,142 views

We just built an artificial egg. It supports full bird development outside a natural shell, and could help hatch massive extinct birds like the South Island giant moa, whose eggs were too big for a living bird to hatch. We rebuilt the egg. Now we’re rebuilding what’s possible.

We just built an artificial egg. It supports full bird development outside a natural shell, and could help hatch massive extinct birds like the South Island giant moa, whose eggs were too big for a living bird to hatch. We rebuilt the egg. Now we’re rebuilding what’s possible.

37,052 views

Blue is super rare in nature. Fewer than 1 in 10 plants have blue flowers. It’s even rarer in animals. Most “blue” isn’t pigment, it’s physics. Tiny structures bend & scatter light so only blue reaches your eyes. It’s really an illusion, and that’s what makes it special. (1/8)

Blue is super rare in nature. Fewer than 1 in 10 plants have blue flowers. It’s even rarer in animals. Most “blue” isn’t pigment, it’s physics. Tiny structures bend & scatter light so only blue reaches your eyes. It’s really an illusion, and that’s what makes it special. (1/8)

40,434 views

Plastic is a macro problem. Breaking is the micro solution. Visit to learn more about X-32, our groundbreaking discovery.

Plastic is a macro problem. Breaking is the micro solution. Visit to learn more about X-32, our groundbreaking discovery.

166,026 views

This isn’t really how it works, but you get it. The woolly mouse went Super Saiyan as a result of edits made to its genes to add woolly mammoth-inspired hair and increased fat storage. Engineering these cold-adapted traits is critical to bringing back a mammoth.

This isn’t really how it works, but you get it. The woolly mouse went Super Saiyan as a result of edits made to its genes to add woolly mammoth-inspired hair and increased fat storage. Engineering these cold-adapted traits is critical to bringing back a mammoth.

14,881 views

Pawsitively exhausted from being so cute. 💖 Just like their distant dog-relatives, our dire wolf pups did a fair amount of sleeping when they were young. But scientists believe most adult wolves sleep around eight hours, usually lightly, with long nods after a big meal and with short naps throughout the day. Solid self care in that neverending quest for hunt-life balance.

Pawsitively exhausted from being so cute. 💖 Just like their distant dog-relatives, our dire wolf pups did a fair amount of sleeping when they were young. But scientists believe most adult wolves sleep around eight hours, usually lightly, with long nods after a big meal and with short naps throughout the day. Solid self care in that neverending quest for hunt-life balance.

95,851 views

We’re launching the Colossal Species Reintroduction Fund: $250K annually to help return missing and at-risk species to the wild. Rewilding restores ecosystems and helps prevent extinctions. This is one more step toward making extinction a thing of the past.

We’re launching the Colossal Species Reintroduction Fund: $250K annually to help return missing and at-risk species to the wild. Rewilding restores ecosystems and helps prevent extinctions. This is one more step toward making extinction a thing of the past.

70,188 views

🐺 The dire wolves are growing fast. You’ve seen the Pupdates… now it’s your turn. Drop your questions below and we’ll have our Manager of Animal Husbandry answer them on video.👇

🐺 The dire wolves are growing fast. You’ve seen the Pupdates… now it’s your turn. Drop your questions below and we’ll have our Manager of Animal Husbandry answer them on video.👇

52,006 views

The woolly mouse is woolly, woolly fast boi

The woolly mouse is woolly, woolly fast boi

22,514 views

Had the gen z intern remix our new artificial egg 🤦‍♀️😅 Why build an artificial egg? To hatch a moa whose egg is 80x the volume of a chicken egg. No bird alive could hatch something that size. The next challenge is scaling up ☝️

Had the gen z intern remix our new artificial egg 🤦‍♀️😅 Why build an artificial egg? To hatch a moa whose egg is 80x the volume of a chicken egg. No bird alive could hatch something that size. The next challenge is scaling up ☝️

11,464 views

🎂 On January 30, 2025, the first female dire wolf was born. Queen Khaleesi. Which means today is her first birthday. Everyone is being extra sweet to her, and she is absolutely gonna get an elite snack pack. No question. Send her some birthday love below. 🥳 👇

🎂 On January 30, 2025, the first female dire wolf was born. Queen Khaleesi. Which means today is her first birthday. Everyone is being extra sweet to her, and she is absolutely gonna get an elite snack pack. No question. Send her some birthday love below. 🥳 👇

17,768 views

Scientists: “They’re powerful apex predators” Us: “Oooh… let’s give them cake” 🎂 🐺

Scientists: “They’re powerful apex predators” Us: “Oooh… let’s give them cake” 🎂 🐺

20,796 views

Videos

LIVE
1.2k

Anya Rossi

sweetdream.ai

SweetDream.aiSponsored•Livecam
Streaming Now

Watch Anya Live

Anya is streaming live right now! Join her private show and enjoy exclusive content.

HD live stream
Exclusive private shows
1.2k viewers online

Free preview available • Premium content

Click to Follow our De-Extinction Journey
0:41
colossal's profile picture

Click to Follow our De-Extinction Journey

Colossal Biosciences®

22,456,455 views • 8 months ago

Click to Follow our De-Extinction Journey
0:35
colossal's profile picture

Click to Follow our De-Extinction Journey

Colossal Biosciences®

12,187,910 views • 8 months ago

Click to Follow our De-Extinction Journey
0:37
colossal's profile picture

Click to Follow our De-Extinction Journey

Colossal Biosciences®

8,781,869 views • 8 months ago

2025 was the year de-extinction went mainstream. Dire wolves. Moa. Woolly mouse. If you thought this year was big, wait until 2026. Follow along.
0:43
colossal's profile picture

2025 was the year de-extinction went mainstream. Dire wolves. Moa. Woolly mouse. If you thought this year was big, wait until 2026. Follow along.

Colossal Biosciences®

4,157,703 views • 8 months ago

2025 was the year de-extinction went mainstream. Dire wolves. Moa. Woolly mouse. If you thought this year was big, wait until 2026. Follow along.
0:37
colossal's profile picture

2025 was the year de-extinction went mainstream. Dire wolves. Moa. Woolly mouse. If you thought this year was big, wait until 2026. Follow along.

Colossal Biosciences®

4,098,475 views • 8 months ago

2025 was the year de-extinction went mainstream. Dire wolves. Moa. Woolly mouse. If you thought this year was big, wait until 2026. Follow along.
0:41
colossal's profile picture

2025 was the year de-extinction went mainstream. Dire wolves. Moa. Woolly mouse. If you thought this year was big, wait until 2026. Follow along.

Colossal Biosciences®

3,095,018 views • 8 months ago

2025 was the year de-extinction went mainstream. Dire wolves. Moa. Woolly mouse. If you thought this year was big, wait until 2026. Follow along.
0:49
colossal's profile picture

2025 was the year de-extinction went mainstream. Dire wolves. Moa. Woolly mouse. If you thought this year was big, wait until 2026. Follow along.

Colossal Biosciences®

2,866,092 views • 8 months ago

2025 was the year de-extinction went mainstream. Dire wolves. Moa. Woolly mouse. If you thought this year was big, wait until 2026. Follow along.
0:24
colossal's profile picture

2025 was the year de-extinction went mainstream. Dire wolves. Moa. Woolly mouse. If you thought this year was big, wait until 2026. Follow along.

Colossal Biosciences®

2,224,152 views • 8 months ago

2025 was the year de-extinction went mainstream. Dire wolves. Moa. Woolly mouse. If you thought this year was big, wait until 2026. Follow along.
0:24
colossal's profile picture

2025 was the year de-extinction went mainstream. Dire wolves. Moa. Woolly mouse. If you thought this year was big, wait until 2026. Follow along.

Colossal Biosciences®

1,985,892 views • 8 months ago

2025 was the year de-extinction went mainstream. Dire wolves. Moa. Woolly mouse. If you thought this year was big, wait until 2026. Follow along.
0:24
colossal's profile picture

2025 was the year de-extinction went mainstream. Dire wolves. Moa. Woolly mouse. If you thought this year was big, wait until 2026. Follow along.

Colossal Biosciences®

1,715,163 views • 8 months ago

2025 was the year de-extinction went mainstream. Dire wolves. Moa. Woolly mouse. If you thought this year was big, wait until 2026. Follow along.
0:43
colossal's profile picture

2025 was the year de-extinction went mainstream. Dire wolves. Moa. Woolly mouse. If you thought this year was big, wait until 2026. Follow along.

Colossal Biosciences®

1,640,802 views • 8 months ago

We’re Colossal Biosciences, the de-extinction company responsible for bringing back the first animals from extinction. Our dire wolf pups, Romulus and Remus, were born on October 1, 2024. Watch these pups grow up on our YouTube channel. Link in bio. These two wolves were returned from extinction using genetic edits derived from a complete dire wolf genome, meticulously reconstructed from ancient DNA found in fossils dating back 11,500 and 72,000 years. This achievement is the result of years of pioneering science, tireless innovation, and unwavering dedication. It marks a major milestone not only for our company, but for science, conservation, and humanity. With the birth of Romulus and Remus, de-extinction is no longer theory—it’s reality. There’s more work ahead, but this moment redefines what’s possible for the planet’s future.
0:42
colossal's profile picture

We’re Colossal Biosciences, the de-extinction company responsible for bringing back the first animals from extinction. Our dire wolf pups, Romulus and Remus, were born on October 1, 2024. Watch these pups grow up on our YouTube channel. Link in bio. These two wolves were returned from extinction using genetic edits derived from a complete dire wolf genome, meticulously reconstructed from ancient DNA found in fossils dating back 11,500 and 72,000 years. This achievement is the result of years of pioneering science, tireless innovation, and unwavering dedication. It marks a major milestone not only for our company, but for science, conservation, and humanity. With the birth of Romulus and Remus, de-extinction is no longer theory—it’s reality. There’s more work ahead, but this moment redefines what’s possible for the planet’s future.

Colossal Biosciences®

2,914,773 views • 1 year ago

🦖 Jurassic Park got a few things wrong. Shocking, I know. 🙃 But real scientists aren’t out here making the same mistakes. We’re reviving lost species, and giving them the best shot at thriving in today’s world. 🎥 Someday they’re gonna make a movie about this.
0:57
colossal's profile picture

🦖 Jurassic Park got a few things wrong. Shocking, I know. 🙃 But real scientists aren’t out here making the same mistakes. We’re reviving lost species, and giving them the best shot at thriving in today’s world. 🎥 Someday they’re gonna make a movie about this.

Colossal Biosciences®

791,822 views • 8 months ago

There are some animals we definitely won't de-extinct. Anything that starred in The Meg is high on that list. What's your pick for the species we should absolutely never bring back?
0:22
colossal's profile picture

There are some animals we definitely won't de-extinct. Anything that starred in The Meg is high on that list. What's your pick for the species we should absolutely never bring back?

Colossal Biosciences®

12,953 views • 6 days ago

The future is so bright, you might need to take your shades OFF for this one. De-extinction is now a reality. Meet Khaleesi—a dire wolf pup, reborn on January 31, 2025, more than 10,000 years after her species vanished. It's not #JurassicPark but this moment signals the start of a new era in biodiversity and ecological restoration. The dire wolf is back, and for Colossal, this is only the beginning.
0:26
colossal's profile picture

The future is so bright, you might need to take your shades OFF for this one. De-extinction is now a reality. Meet Khaleesi—a dire wolf pup, reborn on January 31, 2025, more than 10,000 years after her species vanished. It's not #JurassicPark but this moment signals the start of a new era in biodiversity and ecological restoration. The dire wolf is back, and for Colossal, this is only the beginning.

Colossal Biosciences®

742,811 views • 1 year ago

2025 was the year de-extinction went mainstream. Dire wolves. Moa. Woolly mouse. If you thought this year was big, wait until 2026. Follow along.
0:49
colossal's profile picture

2025 was the year de-extinction went mainstream. Dire wolves. Moa. Woolly mouse. If you thought this year was big, wait until 2026. Follow along.

Colossal Biosciences®

244,856 views • 8 months ago

Convergent evolution is when unrelated species evolve similar traits to adapt to similar environments. Dragonflies and birds both developed wings for flight, yet share no close relative and have completely different wing structures.
0:38
colossal's profile picture

Convergent evolution is when unrelated species evolve similar traits to adapt to similar environments. Dragonflies and birds both developed wings for flight, yet share no close relative and have completely different wing structures.

Colossal Biosciences®

227,641 views • 8 months ago

🦤Why do people say “dodo bird”? We don’t say moa bird. Or chicken bird. Sounds ridiculous, right? So let’s settle this once and for all. It’s just dodo. Cool dodo. Cute dodo. Cuddly dodo. Call it anything you want…as long as it’s not “dodo bird.” We shall consider this settled.
0:22
colossal's profile picture

🦤Why do people say “dodo bird”? We don’t say moa bird. Or chicken bird. Sounds ridiculous, right? So let’s settle this once and for all. It’s just dodo. Cool dodo. Cute dodo. Cuddly dodo. Call it anything you want…as long as it’s not “dodo bird.” We shall consider this settled.

Colossal Biosciences®

259,831 views • 11 months ago

Don’t try this at home, but Colossal Chief Science Officer, Dr. Beth Shapiro, breaks down the extremely complex process of making a dire wolf into a simple seven steps you’ll actually understand.
1:45
colossal's profile picture

Don’t try this at home, but Colossal Chief Science Officer, Dr. Beth Shapiro, breaks down the extremely complex process of making a dire wolf into a simple seven steps you’ll actually understand.

Colossal Biosciences®

332,661 views • 1 year ago

2025 marked a defining year for de-extinction and species preservation. In a global biodiversity crisis, it showed what’s possible when imagination meets action. By looking to the past, we’re working to rebuild ecosystems and restore balance.
2:28
colossal's profile picture

2025 marked a defining year for de-extinction and species preservation. In a global biodiversity crisis, it showed what’s possible when imagination meets action. By looking to the past, we’re working to rebuild ecosystems and restore balance.

Colossal Biosciences®

159,699 views • 8 months ago