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Colossal Biosciences®

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The de-extinction company.

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SOUND ON. You’re hearing the first howl of a dire wolf in over 10,000 years. Meet Romulus and Remus—the world’s first de-extinct animals, born on October 1, 2024. The dire wolf has been extinct for over 10,000 years. These two wolves were brought back from extinction using genetic edits derived from a complete dire wolf genome, meticulously reconstructed by Colossal from ancient DNA found in fossils dating back 11,500 and 72,000 years. This moment marks not only a milestone for us as a company but also a leap forward for science, conservation, and humanity. From the beginning, our goal has been clear: “To revolutionize history and be the first company to use CRISPR technology successfully in the de-extinction of previously lost species.” By achieving this, we continue to push forward our broader mission on—accepting humanity’s duty to restore Earth to a healthier state. But this isn’t just our moment—it’s one for science, our planet, and humankind. All of which we love and are passionate about. Now, close your eyes and listen to that howl once more. Think about what this means for all of us.

SOUND ON. You’re hearing the first howl of a dire wolf in over 10,000 years. Meet Romulus and Remus—the world’s first de-extinct animals, born on October 1, 2024. The dire wolf has been extinct for over 10,000 years. These two wolves were brought back from extinction using genetic edits derived from a complete dire wolf genome, meticulously reconstructed by Colossal from ancient DNA found in fossils dating back 11,500 and 72,000 years. This moment marks not only a milestone for us as a company but also a leap forward for science, conservation, and humanity. From the beginning, our goal has been clear: “To revolutionize history and be the first company to use CRISPR technology successfully in the de-extinction of previously lost species.” By achieving this, we continue to push forward our broader mission on—accepting humanity’s duty to restore Earth to a healthier state. But this isn’t just our moment—it’s one for science, our planet, and humankind. All of which we love and are passionate about. Now, close your eyes and listen to that howl once more. Think about what this means for all of us.

28,470,513 Aufrufe

BREAKING: We're bringing back DRAGONS! The Victorian grassland earless dragon was extinct in the wild. Now it's returning thanks to breakthrough genetics. Follow for the wildest science on Earth.

BREAKING: We're bringing back DRAGONS! The Victorian grassland earless dragon was extinct in the wild. Now it's returning thanks to breakthrough genetics. Follow for the wildest science on Earth.

8,401,521 Aufrufe

We just built an artificial egg. It supports full bird development outside a natural shell, and could help hatch massive extinct birds like the South Island giant moa, whose eggs were too big for a living bird to hatch. We rebuilt the egg. Now we’re rebuilding what’s possible.

We just built an artificial egg. It supports full bird development outside a natural shell, and could help hatch massive extinct birds like the South Island giant moa, whose eggs were too big for a living bird to hatch. We rebuilt the egg. Now we’re rebuilding what’s possible.

34,245 Aufrufe

Whakataukī are ancestral Māori proverbs, short poetic sayings passed down through generations. Rich in metaphor and meaning, they spark reflection and guide growth. Many reference the moa. Here are a few of our favorites. May the moa eat again. (1/9)

Whakataukī are ancestral Māori proverbs, short poetic sayings passed down through generations. Rich in metaphor and meaning, they spark reflection and guide growth. Many reference the moa. Here are a few of our favorites. May the moa eat again. (1/9)

218,227 Aufrufe

Blue is super rare in nature. Fewer than 1 in 10 plants have blue flowers. It’s even rarer in animals. Most “blue” isn’t pigment, it’s physics. Tiny structures bend & scatter light so only blue reaches your eyes. It’s really an illusion, and that’s what makes it special. (1/8)

Blue is super rare in nature. Fewer than 1 in 10 plants have blue flowers. It’s even rarer in animals. Most “blue” isn’t pigment, it’s physics. Tiny structures bend & scatter light so only blue reaches your eyes. It’s really an illusion, and that’s what makes it special. (1/8)

39,493 Aufrufe

Why do we pour time, tech, money and way too many granola bars into this work? Because extinction isn’t just their loss. It’s ours too. Every species saved is a win for the whole planet. Support conservation, in all its forms.

Why do we pour time, tech, money and way too many granola bars into this work? Because extinction isn’t just their loss. It’s ours too. Every species saved is a win for the whole planet. Support conservation, in all its forms.

184,118 Aufrufe

🤯 You’re looking at pigeon primordial germ cells (PGCs) grown in culture for the first time. These stem cells will be key to bringing back the dodo. Until now, this achievement was limited to chickens and geese, but unlocking it in pigeons opens the door to dodo de-extinction.

🤯 You’re looking at pigeon primordial germ cells (PGCs) grown in culture for the first time. These stem cells will be key to bringing back the dodo. Until now, this achievement was limited to chickens and geese, but unlocking it in pigeons opens the door to dodo de-extinction.

110,665 Aufrufe

Emus can’t fly, but they can sprint up to 31 mph(50 km/h). So why’s this chick so hyped? Because we just announced our newest de-extinction project: the South Island giant moa. And if you hadn’t seen your cousin in 400 years, you’d be freaking out too. 🎥HikeNSnorkel r/Eyebleach

Emus can’t fly, but they can sprint up to 31 mph(50 km/h). So why’s this chick so hyped? Because we just announced our newest de-extinction project: the South Island giant moa. And if you hadn’t seen your cousin in 400 years, you’d be freaking out too. 🎥HikeNSnorkel r/Eyebleach

99,090 Aufrufe

Don’t get all judgy, he’s just cold-weather adapted.

Don’t get all judgy, he’s just cold-weather adapted.

116,982 Aufrufe

Plastic is a macro problem. Breaking is the micro solution. Visit to learn more about X-32, our groundbreaking discovery.

Plastic is a macro problem. Breaking is the micro solution. Visit to learn more about X-32, our groundbreaking discovery.

166,012 Aufrufe

Pawsitively exhausted from being so cute. 💖 Just like their distant dog-relatives, our dire wolf pups did a fair amount of sleeping when they were young. But scientists believe most adult wolves sleep around eight hours, usually lightly, with long nods after a big meal and with short naps throughout the day. Solid self care in that neverending quest for hunt-life balance.

Pawsitively exhausted from being so cute. 💖 Just like their distant dog-relatives, our dire wolf pups did a fair amount of sleeping when they were young. But scientists believe most adult wolves sleep around eight hours, usually lightly, with long nods after a big meal and with short naps throughout the day. Solid self care in that neverending quest for hunt-life balance.

95,810 Aufrufe

We’re launching the Colossal Species Reintroduction Fund: $250K annually to help return missing and at-risk species to the wild. Rewilding restores ecosystems and helps prevent extinctions. This is one more step toward making extinction a thing of the past.

We’re launching the Colossal Species Reintroduction Fund: $250K annually to help return missing and at-risk species to the wild. Rewilding restores ecosystems and helps prevent extinctions. This is one more step toward making extinction a thing of the past.

70,188 Aufrufe

🐺 The dire wolves are growing fast. You’ve seen the Pupdates… now it’s your turn. Drop your questions below and we’ll have our Manager of Animal Husbandry answer them on video.👇

🐺 The dire wolves are growing fast. You’ve seen the Pupdates… now it’s your turn. Drop your questions below and we’ll have our Manager of Animal Husbandry answer them on video.👇

51,993 Aufrufe

The woolly mouse is woolly, woolly fast boi

The woolly mouse is woolly, woolly fast boi

22,242 Aufrufe

🎂 On January 30, 2025, the first female dire wolf was born. Queen Khaleesi. Which means today is her first birthday. Everyone is being extra sweet to her, and she is absolutely gonna get an elite snack pack. No question. Send her some birthday love below. 🥳 👇

🎂 On January 30, 2025, the first female dire wolf was born. Queen Khaleesi. Which means today is her first birthday. Everyone is being extra sweet to her, and she is absolutely gonna get an elite snack pack. No question. Send her some birthday love below. 🥳 👇

17,768 Aufrufe

Zoom, zoom, zoom—these wolves have room, room, room. Just like your favorite “in-home, not from the Pleistocene Epoch, overly dramatic house dog,” these wolves get the zoomies. The difference? These wolves aren’t doing laps around a coffee table—they’ve got an entire secure, expansive ecological preserve to zoom around in.

Zoom, zoom, zoom—these wolves have room, room, room. Just like your favorite “in-home, not from the Pleistocene Epoch, overly dramatic house dog,” these wolves get the zoomies. The difference? These wolves aren’t doing laps around a coffee table—they’ve got an entire secure, expansive ecological preserve to zoom around in.

39,204 Aufrufe

"I fear not the man who has practiced 10,000 kicks once, but I fear the man who has practiced one kick 10,000 times. Also… I fear Ice Age apex predators in wolf form. Just sayin’.” 🔊 Sound on for peak kung fu cinema

"I fear not the man who has practiced 10,000 kicks once, but I fear the man who has practiced one kick 10,000 times. Also… I fear Ice Age apex predators in wolf form. Just sayin’.” 🔊 Sound on for peak kung fu cinema

14,015 Aufrufe

Scientists: “They’re powerful apex predators” Us: “Oooh… let’s give them cake” 🎂 🐺

Scientists: “They’re powerful apex predators” Us: “Oooh… let’s give them cake” 🎂 🐺

20,791 Aufrufe

Being found is a huge part of this ferret’s story. Once thought extinct, these were rediscovered in 1981 and brought back through cloning. Using frozen DNA, ViaGen Pets & Equine (a Colossal company) created the first cloned black-footed ferret. 👏

Being found is a huge part of this ferret’s story. Once thought extinct, these were rediscovered in 1981 and brought back through cloning. Using frozen DNA, ViaGen Pets & Equine (a Colossal company) created the first cloned black-footed ferret. 👏

10,926 Aufrufe

Time will tell. Cloning a dinosaur may always be impossible, but with AI, ancestral state reconstruction, and a deeper understanding of genetics, science may one day be able to engineer something convincingly dinosaur-like. 🙂

Time will tell. Cloning a dinosaur may always be impossible, but with AI, ancestral state reconstruction, and a deeper understanding of genetics, science may one day be able to engineer something convincingly dinosaur-like. 🙂

11,667 Aufrufe

Videos

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Click to Follow our De-Extinction Journey

Click to Follow our De-Extinction Journey

Colossal Biosciences®

22,455,450 Aufrufe • vor 5 Monaten

Click to Follow our De-Extinction Journey

Click to Follow our De-Extinction Journey

Colossal Biosciences®

8,781,212 Aufrufe • vor 5 Monaten

2025 was the year de-extinction went mainstream. Dire wolves. Moa. Woolly mouse. If you thought this year was big, wait until 2026. Follow along.

2025 was the year de-extinction went mainstream. Dire wolves. Moa. Woolly mouse. If you thought this year was big, wait until 2026. Follow along.

Colossal Biosciences®

4,157,703 Aufrufe • vor 5 Monaten

2025 was the year de-extinction went mainstream. Dire wolves. Moa. Woolly mouse. If you thought this year was big, wait until 2026. Follow along.

2025 was the year de-extinction went mainstream. Dire wolves. Moa. Woolly mouse. If you thought this year was big, wait until 2026. Follow along.

Colossal Biosciences®

3,094,916 Aufrufe • vor 5 Monaten

2025 was the year de-extinction went mainstream. Dire wolves. Moa. Woolly mouse. If you thought this year was big, wait until 2026. Follow along.

2025 was the year de-extinction went mainstream. Dire wolves. Moa. Woolly mouse. If you thought this year was big, wait until 2026. Follow along.

Colossal Biosciences®

2,865,198 Aufrufe • vor 5 Monaten

2025 was the year de-extinction went mainstream. Dire wolves. Moa. Woolly mouse. If you thought this year was big, wait until 2026. Follow along.

2025 was the year de-extinction went mainstream. Dire wolves. Moa. Woolly mouse. If you thought this year was big, wait until 2026. Follow along.

Colossal Biosciences®

1,715,163 Aufrufe • vor 5 Monaten

2025 was the year de-extinction went mainstream. Dire wolves. Moa. Woolly mouse. If you thought this year was big, wait until 2026. Follow along.

2025 was the year de-extinction went mainstream. Dire wolves. Moa. Woolly mouse. If you thought this year was big, wait until 2026. Follow along.

Colossal Biosciences®

1,640,802 Aufrufe • vor 5 Monaten

We’re Colossal Biosciences, the de-extinction company responsible for bringing back the first animals from extinction. Our dire wolf pups, Romulus and Remus, were born on October 1, 2024. Watch these pups grow up on our YouTube channel. Link in bio. These two wolves were returned from extinction using genetic edits derived from a complete dire wolf genome, meticulously reconstructed from ancient DNA found in fossils dating back 11,500 and 72,000 years. This achievement is the result of years of pioneering science, tireless innovation, and unwavering dedication. It marks a major milestone not only for our company, but for science, conservation, and humanity. With the birth of Romulus and Remus, de-extinction is no longer theory—it’s reality. There’s more work ahead, but this moment redefines what’s possible for the planet’s future.

We’re Colossal Biosciences, the de-extinction company responsible for bringing back the first animals from extinction. Our dire wolf pups, Romulus and Remus, were born on October 1, 2024. Watch these pups grow up on our YouTube channel. Link in bio. These two wolves were returned from extinction using genetic edits derived from a complete dire wolf genome, meticulously reconstructed from ancient DNA found in fossils dating back 11,500 and 72,000 years. This achievement is the result of years of pioneering science, tireless innovation, and unwavering dedication. It marks a major milestone not only for our company, but for science, conservation, and humanity. With the birth of Romulus and Remus, de-extinction is no longer theory—it’s reality. There’s more work ahead, but this moment redefines what’s possible for the planet’s future.

Colossal Biosciences®

2,912,538 Aufrufe • vor 1 Jahr

🦖 Jurassic Park got a few things wrong. Shocking, I know. 🙃 But real scientists aren’t out here making the same mistakes. We’re reviving lost species, and giving them the best shot at thriving in today’s world. 🎥 Someday they’re gonna make a movie about this.

🦖 Jurassic Park got a few things wrong. Shocking, I know. 🙃 But real scientists aren’t out here making the same mistakes. We’re reviving lost species, and giving them the best shot at thriving in today’s world. 🎥 Someday they’re gonna make a movie about this.

Colossal Biosciences®

791,643 Aufrufe • vor 5 Monaten

The future is so bright, you might need to take your shades OFF for this one. De-extinction is now a reality. Meet Khaleesi—a dire wolf pup, reborn on January 31, 2025, more than 10,000 years after her species vanished. It's not #JurassicPark but this moment signals the start of a new era in biodiversity and ecological restoration. The dire wolf is back, and for Colossal, this is only the beginning.

The future is so bright, you might need to take your shades OFF for this one. De-extinction is now a reality. Meet Khaleesi—a dire wolf pup, reborn on January 31, 2025, more than 10,000 years after her species vanished. It's not #JurassicPark but this moment signals the start of a new era in biodiversity and ecological restoration. The dire wolf is back, and for Colossal, this is only the beginning.

Colossal Biosciences®

741,985 Aufrufe • vor 1 Jahr

2025 was the year de-extinction went mainstream. Dire wolves. Moa. Woolly mouse. If you thought this year was big, wait until 2026. Follow along.

2025 was the year de-extinction went mainstream. Dire wolves. Moa. Woolly mouse. If you thought this year was big, wait until 2026. Follow along.

Colossal Biosciences®

244,853 Aufrufe • vor 5 Monaten

Convergent evolution is when unrelated species evolve similar traits to adapt to similar environments. Dragonflies and birds both developed wings for flight, yet share no close relative and have completely different wing structures.

Convergent evolution is when unrelated species evolve similar traits to adapt to similar environments. Dragonflies and birds both developed wings for flight, yet share no close relative and have completely different wing structures.

Colossal Biosciences®

227,570 Aufrufe • vor 5 Monaten

🦤Why do people say “dodo bird”? We don’t say moa bird. Or chicken bird. Sounds ridiculous, right? So let’s settle this once and for all. It’s just dodo. Cool dodo. Cute dodo. Cuddly dodo. Call it anything you want…as long as it’s not “dodo bird.” We shall consider this settled.

🦤Why do people say “dodo bird”? We don’t say moa bird. Or chicken bird. Sounds ridiculous, right? So let’s settle this once and for all. It’s just dodo. Cool dodo. Cute dodo. Cuddly dodo. Call it anything you want…as long as it’s not “dodo bird.” We shall consider this settled.

Colossal Biosciences®

259,514 Aufrufe • vor 8 Monaten

We’re bringing the bluebuck back from extinction. A literal blue, furry grazer with royal-level horns. Humans wiped it out 200 years ago. Now genomics + IVF will help us bring it back. And the tech build along the way could boost antelope conservation across Africa.

We’re bringing the bluebuck back from extinction. A literal blue, furry grazer with royal-level horns. Humans wiped it out 200 years ago. Now genomics + IVF will help us bring it back. And the tech build along the way could boost antelope conservation across Africa.

Colossal Biosciences®

41,437 Aufrufe • vor 1 Monat

We just dropped the Colossal artificial egg: an incubation system that can raise and hatch a chick outside a natural eggshell. Getting to care for these little birds and watch them hatch is an incredible feeling. And this is just the beginning.

We just dropped the Colossal artificial egg: an incubation system that can raise and hatch a chick outside a natural eggshell. Getting to care for these little birds and watch them hatch is an incredible feeling. And this is just the beginning.

Colossal Biosciences®

17,123 Aufrufe • vor 14 Tagen

Don’t try this at home, but Colossal Chief Science Officer, Dr. Beth Shapiro, breaks down the extremely complex process of making a dire wolf into a simple seven steps you’ll actually understand.

Don’t try this at home, but Colossal Chief Science Officer, Dr. Beth Shapiro, breaks down the extremely complex process of making a dire wolf into a simple seven steps you’ll actually understand.

Colossal Biosciences®

332,250 Aufrufe • vor 1 Jahr

The world’s first de-extincted animals, dire wolf brothers Romulus and Remus, were born on October 1, 2024. They are best buds, growing stronger every day, and they live together on a secure, expansive ecological preserve. And while they’re BFFs, they are being socialized with other wolves, as appropriate, to help develop strong social skills. Music: Grover Washington Jr. - “Just the Two of Us (feat. Bill Withers)”

The world’s first de-extincted animals, dire wolf brothers Romulus and Remus, were born on October 1, 2024. They are best buds, growing stronger every day, and they live together on a secure, expansive ecological preserve. And while they’re BFFs, they are being socialized with other wolves, as appropriate, to help develop strong social skills. Music: Grover Washington Jr. - “Just the Two of Us (feat. Bill Withers)”

Colossal Biosciences®

257,426 Aufrufe • vor 1 Jahr

Let’s make majestic frolicking a thing ❄️🐺 When you see these magnificent and powerful creatures moving through the snow, remember the vital role predators play in our world. The dire wolf, sometimes called the “great wolf,” holds deep cultural and ecological significance across North America, especially in Indigenous traditions. In conversations with Indigenous groups, ecologists, and landowners, one request stood out: work on a carnivore alongside herbivores. Wolves, as keystone species, are vital for healthy ecosystems yet often misunderstood. This project goes beyond de-extinction and conservation—it’s about reframing the conversation on wolves and their role in biodiversity.

Let’s make majestic frolicking a thing ❄️🐺 When you see these magnificent and powerful creatures moving through the snow, remember the vital role predators play in our world. The dire wolf, sometimes called the “great wolf,” holds deep cultural and ecological significance across North America, especially in Indigenous traditions. In conversations with Indigenous groups, ecologists, and landowners, one request stood out: work on a carnivore alongside herbivores. Wolves, as keystone species, are vital for healthy ecosystems yet often misunderstood. This project goes beyond de-extinction and conservation—it’s about reframing the conversation on wolves and their role in biodiversity.

Colossal Biosciences®

200,420 Aufrufe • vor 1 Jahr

🚨👨‍🔬 Big news: Dr. Andrew Pask, mastermind of the thylacine comeback, is now full time at Colossal as Chief Biology Officer. He’ll lead Colossal Australia 🇦🇺 in partnership with @‌unimelb, advancing de-extinction and conservation on a global scale.

🚨👨‍🔬 Big news: Dr. Andrew Pask, mastermind of the thylacine comeback, is now full time at Colossal as Chief Biology Officer. He’ll lead Colossal Australia 🇦🇺 in partnership with @‌unimelb, advancing de-extinction and conservation on a global scale.

Colossal Biosciences®

107,222 Aufrufe • vor 9 Monaten

Cane toads wreaked havoc in Australia after their 1935 introduction, poisoning native predators like the northern quoll. But our genetic study found that a single letter change in 3.5 billion base pairs could offer resistance and bring real hope for survival.

Cane toads wreaked havoc in Australia after their 1935 introduction, poisoning native predators like the northern quoll. But our genetic study found that a single letter change in 3.5 billion base pairs could offer resistance and bring real hope for survival.

Colossal Biosciences®

98,308 Aufrufe • vor 8 Monaten