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Shorts

Cells can pass proteins and RNA to each other through tubes that act as a channel between their membranes.

Cells can pass proteins and RNA to each other through tubes that act as a channel between their membranes.

192,223 Aufrufe

Proteins that allow water to move in and out of cells help shape the development of new blood vessels.

Proteins that allow water to move in and out of cells help shape the development of new blood vessels.

46,994 Aufrufe

Evidence of artefactual calcium microwaves during calcium imaging of neurons in the hippocampus.

Evidence of artefactual calcium microwaves during calcium imaging of neurons in the hippocampus.

59,644 Aufrufe

Enhanced single RNA imaging reveals dynamic gene expression in live animals.

Enhanced single RNA imaging reveals dynamic gene expression in live animals.

83,235 Aufrufe

Chronic Ca2+ imaging of cortical neurons with long-term expression of GCaMP-X.

Chronic Ca2+ imaging of cortical neurons with long-term expression of GCaMP-X.

86,681 Aufrufe

Researchers present a platform for cardiac tissue cultivation with 3D ring-shaped cardiac tissues generated from human stem cell-derived cardiomyocytes.

Researchers present a platform for cardiac tissue cultivation with 3D ring-shaped cardiac tissues generated from human stem cell-derived cardiomyocytes.

51,700 Aufrufe

The path we take while walking on rugged terrain can be mathematically predicted. 🔗

The path we take while walking on rugged terrain can be mathematically predicted. 🔗

38,320 Aufrufe

Researchers have developed Opto-RhoGEFs, an optimised optogenetic toolbox to reversibly control Rho GTPase activity, advancing the ability to manipulate the barrier between endothelial cells.

Researchers have developed Opto-RhoGEFs, an optimised optogenetic toolbox to reversibly control Rho GTPase activity, advancing the ability to manipulate the barrier between endothelial cells.

48,775 Aufrufe

Through monitoring a large group of marmosets, researchers have categorised their behaviours to find baselines for typical and atypical responses that can help us study psychiatric disorders.

Through monitoring a large group of marmosets, researchers have categorised their behaviours to find baselines for typical and atypical responses that can help us study psychiatric disorders.

29,475 Aufrufe

An imaging system with an ultra-wide field of view allows scientists to track millions of cells at once in large 3D tissues and embryos.

An imaging system with an ultra-wide field of view allows scientists to track millions of cells at once in large 3D tissues and embryos.

26,422 Aufrufe

Plant roots can rapidly change the acidity of their cell walls and the root-soil interface to efficiently navigate in the soil environment.

Plant roots can rapidly change the acidity of their cell walls and the root-soil interface to efficiently navigate in the soil environment.

41,084 Aufrufe

🧵 1/ Female #ReproductiveBiology is, unfortunately, notoriously understudied. So maybe it’s no surprise that a supposedly useless ‘developmental leftover’ in the ovaries could turn out to be...not so useless after all. Meet the rete ovarii 👇

🧵 1/ Female #ReproductiveBiology is, unfortunately, notoriously understudied. So maybe it’s no surprise that a supposedly useless ‘developmental leftover’ in the ovaries could turn out to be...not so useless after all. Meet the rete ovarii 👇

21,881 Aufrufe

New microscopy technology enables nanoscale imaging of centimetre-scale tissues, making it possible to image the entire expanded mouse brain at cellular and subcellular resolution. #ReviewedPreprint

New microscopy technology enables nanoscale imaging of centimetre-scale tissues, making it possible to image the entire expanded mouse brain at cellular and subcellular resolution. #ReviewedPreprint

35,249 Aufrufe

Fibronectin, a key component of the vessel wall, triggers smooth muscle cells to release collagen-rich extracellular vesicles that guide their movement during vessel repair and atherosclerosis.

Fibronectin, a key component of the vessel wall, triggers smooth muscle cells to release collagen-rich extracellular vesicles that guide their movement during vessel repair and atherosclerosis.

13,852 Aufrufe

Controlling the forces needed to move around is pretty complicated for soft-bodied organisms. Researchers have implemented a new technique for measuring these crawling forces with nanonewton precision in fruit fly larvae.

Controlling the forces needed to move around is pretty complicated for soft-bodied organisms. Researchers have implemented a new technique for measuring these crawling forces with nanonewton precision in fruit fly larvae.

27,923 Aufrufe

Calcium and bicarbonate signalling pathways have pivotal, resonating roles in matching ATP production to demand.

Calcium and bicarbonate signalling pathways have pivotal, resonating roles in matching ATP production to demand.

30,542 Aufrufe

New microscopy technology enables nanoscale imaging of centimetre-scale tissues, making it possible to image the entire expanded mouse brain at cellular and subcellular resolution. #ReviewedPreprint

New microscopy technology enables nanoscale imaging of centimetre-scale tissues, making it possible to image the entire expanded mouse brain at cellular and subcellular resolution. #ReviewedPreprint

27,496 Aufrufe

Generating active T1 transitions through mechanochemical feedback.

Generating active T1 transitions through mechanochemical feedback.

26,108 Aufrufe

Ultrastructural reconstructions of T. brucei reveal that the endosomal system in trypanosomes forms a continuous membrane system instead of being compartmentalised.

Ultrastructural reconstructions of T. brucei reveal that the endosomal system in trypanosomes forms a continuous membrane system instead of being compartmentalised.

19,618 Aufrufe

One protein, two opposing roles: This ‘compelling’ study shows how the same signalling molecule can drive either protrusion or retraction in migrating cells depending on its concentration and activation dynamics.

One protein, two opposing roles: This ‘compelling’ study shows how the same signalling molecule can drive either protrusion or retraction in migrating cells depending on its concentration and activation dynamics.

10,601 Aufrufe

Videos

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For the first time, scientists analysed the connectome for part of the brain in the common octopus involved in long-term memory. Here, they use #ElectronMicroscopy to trace the length of an axon micron by micron.

For the first time, scientists analysed the connectome for part of the brain in the common octopus involved in long-term memory. Here, they use #ElectronMicroscopy to trace the length of an axon micron by micron.

eLife - the journal

107,274 Aufrufe • vor 2 Jahren

The centrosome decides which branch extending from the body of microglia will successfully engulf and clear away dead neurons.

The centrosome decides which branch extending from the body of microglia will successfully engulf and clear away dead neurons.

eLife - the journal

103,205 Aufrufe • vor 3 Jahren

Enhanced single RNA imaging reveals dynamic gene expression in live animals.

Enhanced single RNA imaging reveals dynamic gene expression in live animals.

eLife - the journal

83,235 Aufrufe • vor 3 Jahren

With three simple steps and in just 48 hr, EZ Clear effectively renders adult mouse organs optically transparent while preserving signals from fluorescent reporters.

With three simple steps and in just 48 hr, EZ Clear effectively renders adult mouse organs optically transparent while preserving signals from fluorescent reporters.

eLife - the journal

60,459 Aufrufe • vor 3 Jahren

Can you infer cause and effect between genes without disturbing the cell? 🧬 This study shows how natural “noise” in gene expression can reveal directed gene–gene interactions.

Can you infer cause and effect between genes without disturbing the cell? 🧬 This study shows how natural “noise” in gene expression can reveal directed gene–gene interactions.

eLife - the journal

11,164 Aufrufe • vor 4 Monaten

New microscopy technology enables nanoscale imaging of centimetre-scale tissues, making it possible to image the entire expanded mouse brain at cellular and subcellular resolution. #ReviewedPreprint

New microscopy technology enables nanoscale imaging of centimetre-scale tissues, making it possible to image the entire expanded mouse brain at cellular and subcellular resolution. #ReviewedPreprint

eLife - the journal

38,026 Aufrufe • vor 2 Jahren

A novel method for imaging glutamate receptors in situ via #CryoET.

A novel method for imaging glutamate receptors in situ via #CryoET.

eLife - the journal

24,691 Aufrufe • vor 1 Jahr

Structural insights into actin isoforms #CryoEM

Structural insights into actin isoforms #CryoEM

eLife - the journal

30,434 Aufrufe • vor 3 Jahren

“This fundamental work provides a creative and thoughtful analysis of rodent foraging behavior” Mice can take shortcuts to find food, demonstrating their ability to make a mental map of their surroundings.

“This fundamental work provides a creative and thoughtful analysis of rodent foraging behavior” Mice can take shortcuts to find food, demonstrating their ability to make a mental map of their surroundings.

eLife - the journal

18,731 Aufrufe • vor 1 Jahr

Retinal motion statistics during natural locomotion.

Retinal motion statistics during natural locomotion.

eLife - the journal

22,638 Aufrufe • vor 3 Jahren

Mechanical forces pattern endocardial Notch activation via mTORC2-PKC pathway. #DevBio

Mechanical forces pattern endocardial Notch activation via mTORC2-PKC pathway. #DevBio

eLife - the journal

11,665 Aufrufe • vor 1 Jahr

What makes one member of the species behave differently from another? It's a core problem in behavioural #neuroscience. This valuable study seeks an answer for the specific case of the fruit fly expressing preferences for one odour over another.

What makes one member of the species behave differently from another? It's a core problem in behavioural #neuroscience. This valuable study seeks an answer for the specific case of the fruit fly expressing preferences for one odour over another.

eLife - the journal

10,043 Aufrufe • vor 1 Jahr

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