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Microsoft researchers introduce MatterGen, a model that can discover new materials tailored to specific needs—like efficient solar cells or CO2 recycling—advancing progress beyond trial-and-error experiments.

Microsoft researchers introduce MatterGen, a model that can discover new materials tailored to specific needs—like efficient solar cells or CO2 recycling—advancing progress beyond trial-and-error experiments.

1,330,126 views

Robots are getting smarter, but how can their hardware match that growth? New Microsoft Research findings show that moving AI inference beyond the robot can improve task success, boost efficiency, and support more advanced physical AI workloads.

Robots are getting smarter, but how can their hardware match that growth? New Microsoft Research findings show that moving AI inference beyond the robot can improve task success, boost efficiency, and support more advanced physical AI workloads.

21,465 views

LLMs do not get smarter just by remembering more. EvoLib turns experience into evolving knowledge, taking reusable skills and insights that help models learn and adapt across tasks long after deployment.

LLMs do not get smarter just by remembering more. EvoLib turns experience into evolving knowledge, taking reusable skills and insights that help models learn and adapt across tasks long after deployment.

23,495 views

Cryptographic code supports vital protections in modern computing systems. Learn how a new method helps verify code as developers write it while preserving speed and adaptability as it gets implemented and evolves.

Cryptographic code supports vital protections in modern computing systems. Learn how a new method helps verify code as developers write it while preserving speed and adaptability as it gets implemented and evolves.

23,154 views

AI agents often fail because their instructions, or skills, are manually modified with no guarantee of improvement. Learn how SkillOpt turns skill editing into a training process, making agent behavior more reliable without changing model weights:

AI agents often fail because their instructions, or skills, are manually modified with no guarantee of improvement. Learn how SkillOpt turns skill editing into a training process, making agent behavior more reliable without changing model weights:

20,583 views

Safe agents don’t guarantee a safe ecosystem of interconnected agents. Microsoft Research examines what breaks when AI agents interact and why network-level risks require new approaches. Learn more:

Safe agents don’t guarantee a safe ecosystem of interconnected agents. Microsoft Research examines what breaks when AI agents interact and why network-level risks require new approaches. Learn more:

20,385 views

Vega turns a full credential into a single proof, sharing only what is needed and nothing more, with performance that works in real apps.

Vega turns a full credential into a single proof, sharing only what is needed and nothing more, with performance that works in real apps.

18,083 views

Aurora 1.5 adds 22 more variables, hourly temporal resolution, and probabilistic ensemble forecasting to the Aurora foundation model, making it more useful for real-world weather, climate, and energy applications.

Aurora 1.5 adds 22 more variables, hourly temporal resolution, and probabilistic ensemble forecasting to the Aurora foundation model, making it more useful for real-world weather, climate, and energy applications.

13,237 views

Introducing GridSFM, a small foundation model that can predict AC optimal power flow in milliseconds, boosting efficiency and unlocking cost savings. Learn how GridSFM gives grid operators direct visibility into congestion, stability, and system health:

Introducing GridSFM, a small foundation model that can predict AC optimal power flow in milliseconds, boosting efficiency and unlocking cost savings. Learn how GridSFM gives grid operators direct visibility into congestion, stability, and system health:

15,213 views

MatterSim is expanding what AI can do for materials science—from faster large-scale simulations to MatterSim-MT, a new multi-task model for simulating properties beyond potential energy surfaces alone.

MatterSim is expanding what AI can do for materials science—from faster large-scale simulations to MatterSim-MT, a new multi-task model for simulating properties beyond potential energy surfaces alone.

14,733 views

Using SocialReasoning Bench, we observed a stable pattern across models—agents execute competently, but fail to consistently improve the user’s position, even with explicit instructions to optimize for user interest.

Using SocialReasoning Bench, we observed a stable pattern across models—agents execute competently, but fail to consistently improve the user’s position, even with explicit instructions to optimize for user interest.

12,812 views

AutoAdapt automates the design and tuning of domain adaptation workflows for large language models. It improves performance without requiring additional compute, making deployment more accessible:

AutoAdapt automates the design and tuning of domain adaptation workflows for large language models. It improves performance without requiring additional compute, making deployment more accessible:

10,753 views

In Episode 1 of the podcast “The AI Revolution in Medicine, Revisited,” host Peter Lee, president of Microsoft Research, & guests Dr. Christopher A. Longhurst, MD & Dr. Sara Murray discuss how generative AI is impacting patient care & workflows in healthcare:

In Episode 1 of the podcast “The AI Revolution in Medicine, Revisited,” host Peter Lee, president of Microsoft Research, & guests Dr. Christopher A. Longhurst, MD & Dr. Sara Murray discuss how generative AI is impacting patient care & workflows in healthcare:

18,494 views

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Coming May 14 at Microsoft Research Forum: a new release and demo from MSR AI Frontiers. Plus new work on Agentic GitHub Workflows, Real-time agent verification, Energy-based fine-tuning, and Guiding the AI transition. Register now:
0:35
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Coming May 14 at Microsoft Research Forum: a new release and demo from MSR AI Frontiers. Plus new work on Agentic GitHub Workflows, Real-time agent verification, Energy-based fine-tuning, and Guiding the AI transition. Register now:

Microsoft Research

17,748,603 views • 5 months ago

The latest Microsoft Research Forum episode is now available on-demand. Explore new ARO, Dion2, Magentic Marketplace, OptiMind, Agent Lightning, and Healthbots. Register to watch:
1:02
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The latest Microsoft Research Forum episode is now available on-demand. Explore new ARO, Dion2, Magentic Marketplace, OptiMind, Agent Lightning, and Healthbots. Register to watch:

Microsoft Research

21,202,439 views • 7 months ago

New tools, models, repos, and papers out of Microsoft Research are here. Use AI and agents? It's worth watching: • MagenticLite from MSR AI Frontiers • Agentic GitHub workflows • Verification‑first agents • Meaning‑matching fine‑tuning • AI transition + the economy
2:17
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New tools, models, repos, and papers out of Microsoft Research are here. Use AI and agents? It's worth watching: • MagenticLite from MSR AI Frontiers • Agentic GitHub workflows • Verification‑first agents • Meaning‑matching fine‑tuning • AI transition + the economy

Microsoft Research

3,447,138 views • 5 months ago

AI is transforming the way we all live, work, and think. Join us for Microsoft Research Forum, where you'll learn about the most recent advances and hear bold new ideas from the global research community. See you on June 4 for Episode 3. Register now.
0:30
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AI is transforming the way we all live, work, and think. Join us for Microsoft Research Forum, where you'll learn about the most recent advances and hear bold new ideas from the global research community. See you on June 4 for Episode 3. Register now.

Microsoft Research

22,477,328 views • 2 years ago

Biology doesn't operate in silos, and neither should the AI representation of it. Quine is an early-stage research effort to create a multimodal world model of biology. By connecting insights across biological scales and modalities, Quine helps scientists computationally search a space far larger than intuition allows and prioritize hypotheses before they reach the lab. Experimental results provide important feedback, helping researchers sharpen future research directions.
1:58
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Biology doesn't operate in silos, and neither should the AI representation of it. Quine is an early-stage research effort to create a multimodal world model of biology. By connecting insights across biological scales and modalities, Quine helps scientists computationally search a space far larger than intuition allows and prioritize hypotheses before they reach the lab. Experimental results provide important feedback, helping researchers sharpen future research directions.

Microsoft Research

41,768 views • 18 days ago

Today in the journal Science: BioEmu from Microsoft Research AI for Science. This generative deep learning method emulates protein equilibrium ensembles – key for understanding protein function at scale.
1:53
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Today in the journal Science: BioEmu from Microsoft Research AI for Science. This generative deep learning method emulates protein equilibrium ensembles – key for understanding protein function at scale.

Microsoft Research

416,325 views • 1 year ago

Custom-made molecules are advancing medicine, materials, and agriculture, but producing them is slow and expensive. A new Nature paper highlights RetroChimera, a predictive model that helps accelerate chemical synthesis, helping researchers explore a wide range of molecules.:
0:20
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Custom-made molecules are advancing medicine, materials, and agriculture, but producing them is slow and expensive. A new Nature paper highlights RetroChimera, a predictive model that helps accelerate chemical synthesis, helping researchers explore a wide range of molecules.:

Microsoft Research

21,088 views • 26 days ago

The wait is over! Microsoft Research is sharing Skala, the new exchange-correlation functional, marking a major milestone in the accuracy/cost trade-off in DFT. Help us learn from your testing so we can improve. Available on Azure AI Foundry and GitHub.
1:20
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The wait is over! Microsoft Research is sharing Skala, the new exchange-correlation functional, marking a major milestone in the accuracy/cost trade-off in DFT. Help us learn from your testing so we can improve. Available on Azure AI Foundry and GitHub.

Microsoft Research

127,487 views • 1 year ago

A look at how coding agents behave at scale; evaluating AI models that find lymphoma lesions in PET/CT scans; understanding AI chatbot dependence; and advancing large-scale decision-making systems. Dive into the latest issue of Research Focus.:
2:00
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A look at how coding agents behave at scale; evaluating AI models that find lymphoma lesions in PET/CT scans; understanding AI chatbot dependence; and advancing large-scale decision-making systems. Dive into the latest issue of Research Focus.:

Microsoft Research

16,728 views • 1 month ago

Microsoft Chief Scientific Officer Eric Horvitz on what stood out at NeurIPS 2025, what’s next, and why these moments matter for the future of AI research.
2:11
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Microsoft Chief Scientific Officer Eric Horvitz on what stood out at NeurIPS 2025, what’s next, and why these moments matter for the future of AI research.

Microsoft Research

86,914 views • 10 months ago

What if pathology foundation models could do more with less? GigaPath-Flash and GigaTIME-Flash cut computational demands while maintaining strong performance, opening the door to larger studies and broader exploration.
0:20
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What if pathology foundation models could do more with less? GigaPath-Flash and GigaTIME-Flash cut computational demands while maintaining strong performance, opening the door to larger studies and broader exploration.

Microsoft Research

18,289 views • 1 month ago

Orchard is an open-source framework for the research community to train and evaluate AI agents across task types. It reduces complexity while supporting strong performance from smaller models by enabling researchers to reuse the same infrastructure.
0:20
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Orchard is an open-source framework for the research community to train and evaluate AI agents across task types. It reduces complexity while supporting strong performance from smaller models by enabling researchers to reuse the same infrastructure.

Microsoft Research

26,266 views • 2 months ago

Skala 1.1, the updated deep-learning exchange-correlation functional from Microsoft Research, provides greater accuracy, expanded accessibility across the computational chemistry ecosystem, and a living benchmark to track computational performance.
0:20
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Skala 1.1, the updated deep-learning exchange-correlation functional from Microsoft Research, provides greater accuracy, expanded accessibility across the computational chemistry ecosystem, and a living benchmark to track computational performance.

Microsoft Research

18,546 views • 1 month ago

Today, we welcome the 2026 Microsoft Research Fellowship cohort, an inspiring global community of fellows and advisors helping to shape what’s next across science, technology, and society. Join us in celebrating this year’s recipients: These contributions span the following themes: • AI for global and societal impact • AI fundamentals: scalable reasoning, model adaption and evaluation • Biological and scientific modeling • Foundational systems & infrastructure for AI • Human-AI collaboration and interaction • Multimodal & embodied intelligence
1:21
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Today, we welcome the 2026 Microsoft Research Fellowship cohort, an inspiring global community of fellows and advisors helping to shape what’s next across science, technology, and society. Join us in celebrating this year’s recipients: These contributions span the following themes: • AI for global and societal impact • AI fundamentals: scalable reasoning, model adaption and evaluation • Biological and scientific modeling • Foundational systems & infrastructure for AI • Human-AI collaboration and interaction • Multimodal & embodied intelligence

Microsoft Research

50,209 views • 6 months ago

LLMs do not get smarter just by remembering more. EvoLib turns experience into evolving knowledge, taking reusable skills and insights that help models learn and adapt across tasks long after deployment.
0:20
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LLMs do not get smarter just by remembering more. EvoLib turns experience into evolving knowledge, taking reusable skills and insights that help models learn and adapt across tasks long after deployment.

Microsoft Research

23,495 views • 2 months ago

A path, a fence, a knot. MindTopo sets a new benchmark for testing how AI understands topological relationships and highlights new opportunities to strengthen spatial reasoning and planning.
0:20
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A path, a fence, a knot. MindTopo sets a new benchmark for testing how AI understands topological relationships and highlights new opportunities to strengthen spatial reasoning and planning.

Microsoft Research

17,952 views • 2 months ago

Radiology AI is evolving beyond report generation. CARE-X explores a unified approach that combines flexible reasoning, calibrated predictions, and measurement-based tools for chest X-ray interpretation.
0:20
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Radiology AI is evolving beyond report generation. CARE-X explores a unified approach that combines flexible reasoning, calibrated predictions, and measurement-based tools for chest X-ray interpretation.

Microsoft Research

17,983 views • 2 months ago

Small language models learn to negotiate with SocialRL, PazaBench V2 expands speech AI evaluation across African languages, and EvoLib helps agents turn experience into knowledge. Plus: new methods for more reliable A/B testing and advances in AI-driven precision oncology.
2:00
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Small language models learn to negotiate with SocialRL, PazaBench V2 expands speech AI evaluation across African languages, and EvoLib helps agents turn experience into knowledge. Plus: new methods for more reliable A/B testing and advances in AI-driven precision oncology.

Microsoft Research

19,304 views • 2 months ago

Cryptographic code supports vital protections in modern computing systems. Learn how a new method helps verify code as developers write it while preserving speed and adaptability as it gets implemented and evolves.
0:20
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Cryptographic code supports vital protections in modern computing systems. Learn how a new method helps verify code as developers write it while preserving speed and adaptability as it gets implemented and evolves.

Microsoft Research

23,154 views • 3 months ago